The invention discloses a traditional Chinese medicine composition for treating chronic renal failure and complications thereof. The traditional Chinese medicine composition is prepared from parched hawthorn fruits, parched pericarpium citri reticulatae, radix angelica sinensis, parched radix paeoniae alba, fructus aurantii parched with bran, pericarpium citri reticulatae viride, radix paeoniae rubra, flos carthami, periostracum cicada, raw radix astragalis, rhizoma curcumae parched with aged vinegar, rhizoma chuanxiong, parched cowherb seeds, rhizoma sparganii parched with aged vinegar, Chinese magnoliavine fruits baked with honey, herb of snow of June, ginseng, prepared radix et rhizoma rhei, honey-fried licorice roots, rhizoma atractylodis macrocephalae parched with soil, rhizoma smilacis glabrae, cassia twigs, leeches, eupolyphaga sinensis and lumbricus. According to the traditional Chinese medicine composition, 25 traditional Chinese medicine materials are carefully selected based on the treatment principles of mainly treating root causes, combining symptoms with root causes, strengthening the body resistance to eliminate pathogenic factors and coordinating yin and yang and have the effects of strengthening the spleen and benefiting qi, stimulating menstrual flow and activating blood circulation, removing damp turbidity toxins, and nourishing the lung, chronic renal failure and uremia can be rapidly and effectively treated, and experiments show that the effective rate of the traditional Chinese medicine composition on uremia reaches 70% or above.