159 results about "Case fatality rate" patented technology

The invention relates to the field of monitoring of health of livestock and discloses a method for monitoring health of domestic animals and a system. The method comprises the steps: adorning each domestic animal with an electronic tag, arranging a corresponding electronic tag reader in an exercise area of the domestic animals, and arranging an image pick-up device, which is used for acquiring video images of exercise of the domestic animals, in the exercise area of the domestic animals; acquiring an electronic tag identity and individual moving track information corresponding to the corresponding electronic tag identity of each domestic animal by using the video images acquired by the electronic tag reader and the image pick-up device; acquiring a total amount of displacements of each domestic animal once in each interval time T1 by using the individual moving track information; acquiring feed intake condition of each domestic animal; and acquiring water intake condition of each domestic animal. According to the method and the system, moving tracks of domestic animal individuals can be tracked in real time based on electronic tag identities of the domestic animals, locations, amount of exercise, feed intake condition and water intake condition can be monitored, the accurate monitoring on health statuses of the domestic animal individuals is facilitated, and the medication andcase-fatality rate of the domestic animals is reduced.

A system and method are provided for diagnosis of animal respiratory diseases using auscultation techniques. Animal lung sounds are recorded and stored as digitized data. Algorithms are applied to the data producing an output indicative of the health of the animal. Another method determines effectiveness of antibiotics administered to animals based upon observed relationships between lung score categories obtained from auscultation. A comparison is made between sample populations of animals that receive different classifications of antibiotics, and this data is compared to lung score categories observed for each of the animals that received the antibiotics. A statistical analysis is conducted to confirm statistical differences in case fatality rates between lung score categories. Insignificant differences in mortality rates across a range of lung score categories indicates the particular antibiotic administered is not effective, whereas a reduced fatality rate associated with lower lung scores indicates a level of antibiotic effectiveness.

A photoelectric factor (PEF) that is corrected for standoff effects is obtained from measurements made with a single detector. A first PEF is obtained using a first pair of soft and hard windows and a second PEF is obtained using a second pair of soft and hard windows. Additional correction to the PEF may be made using a formation density measured by the logging tool.

It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b)

The invention discloses a traditional Chinese preparation used for treating myocardial infarction caused by myocardial ischemia which comprises the following traditional Chinese materials with the weight account: ginseng of 17 to 22, water frog of 8 to 12, schisandra of 8 to 12, aconite of 8 to 12, salvia of 8 to 12, platyciad semen of 18 to 22, gadfly of 8 to 12, pinellia ternate of 8 to 12, panax notoginseng of 8 to 12, ligusticum wallichii of 8 to 12, musk of 0.8 to 1.2, melon of 13 to 17, Chinese onion of 13 to 17. The invention has the advantages of replenishing qi, activating blood and eliminating phlegm, treating myocardial infarction caused by myocardial ischemia by combining with the western medicine treatment, and reducing the incidence of arrhythmia, pump failure, embolization and other complications obviously; intravenous thromboly treatment significantly lowers the hospitalized death rate.

The invention relates to a hepatic functional reserve detector capable of removing blood oxygen fluctuation interference. The hepatic functional reserve detector consists of a photoelectric finger clip sensor, a data memory, a liquid crystal display module, a light source driving circuit, a microprocessor, a signal separating circuit, a signal amplifying circuit, an A/D (analog/digital) conversion circuit, a wireless communication module and a computer, the photoelectric finger clip sensor is respectively connected with the data memory and the liquid crystal display module via the light source driving circuit and the microprocessor, the photoelectric finger clip sensor is connected with the microprocessor via the signal separating circuit, the signal amplifying circuit and the A/D conversion circuit, the microprocessor is connected with the wireless communication module, and the computer is connected with the wireless communication module via Bluetooth. A concentration spectrum of indocyanine green (ICG) pigment used as indicator is separated from a blood oxygen absorbing spectrum, inference of low blood oxygen and blood oxygen fluctuation to pigment concentration measurement is suppressed, a diluted concentration curve of the ICG pigment injected via a vein is accurately measured, the purpose of non-invasively and continuously measuring cardiovascular and hepatic haemodynamics parameters such as pigment blood plasma disappearance rate K, 15-minute detaining rate R15 and the like is achieved, surgery risks can be accurately predicted by means of detecting hepatic functional reserve, a proper therapy mode is selected, and operative mortality and postoperative complications can be effectively reduced.

The invention belongs to the medical field, providing a process for screening colorectal cancer, which screens colorectal cancer through utilizing the hyper-methylation of SFRP 2 gene in feces, and finishes the screening through making specimen, collecting data and treating data. The invention has extreme higher accuracy, and provides a new process for the early discovery and early diagnosis treatment, has reasonable design, free wound, small suffering and low cost, can be a screening process of colorectal cancer, which can increase the curative rate of colorectal cancer at large amplitude if applied in clinics, reduces the fatality rate of colorectal cancer in our country, and has extreme higher economical and social benefits.

The invention relates to a freeze-drying composition of a posaconazole prodrug and a preparation method and application of the freeze-drying composition of the posaconazole prodrug. The freeze-drying composition has the advantages that the freeze-drying composition is high in water solubility, and safety of the freeze-drying composition is guaranteed due to the fact that cyclodextrins auxiliary materials need not to be added during the preparation of the freeze-drying composition; the freeze-drying composition is suitable for being used for treating various amphotericin-intolerant or refractory adult invasive fungal infections; the freeze-drying composition is used as a preventive drug for high-risk patients, the freeze-drying composition is applicable to patients above 13 years old and with impaired immunity and especially applicable to patients who have graft versus host disease (GVHD) after hematopoietic stem cell transplant, patients with leukemia and patients with long-term leukopenia due to chemotherapy; compared with control drugs such as fluconazole and itraconazole, the freeze-drying composition can effectively prevent invasive aspergillosis and can lower the mortality related to the invasive fungal infections.

The present invention is mass spectral model for detecting liver cancer serum characteristic protein and its preparation process, and belongs to the field of protein fingerprint detecting technology. The present invention screens 17 characteristic proteins including 6 up regulation proteins and 11 down regulation proteins, selects two or more proteins out of the 17 characteristic proteins and establishes two or more stage classification tree with the clinical peak values of the proteins to constitute the detection model for detecting the liver cancer serum characteristic protein. The present invention lays foundation for further discovering new liver cancer biological mark, and the model has over 90 % specificity, sensitivity and positive predicting rate in liver cancer diagnosis.

The invention relates to a brain fixed-point sub-hypothermia control device. The brain fixed-point sub-hypothermia control device comprises an intrusive guide tube, temperature detection elements, a control system, a liquid cooling device and a liquid pushing device, wherein the temperature detection elements (2, 2') are used for respectively monitoring the temperatures of an inlet and an outlet of the intrusive guide tube (1); the temperature detection element (2'') is used for monitoring the temperature of the output cooling liquid of the liquid cooling device (4); and the control system (3) is used for sending a control signal to start the liquid pushing device (5) to push the cooled liquid into the inlet of the intrusive guide tube at a certain speed. With the adoption of the brain fixed-point sub-hypothermia control device, the brain cooling part can be accurately positioned, the cooling process is timely and quick, and the sub-hypothermia state can be accurately and reliably maintained; in addition, acute and serious cerebral edema can be controlled, and conditions are created for promoting recovery of brain function, so that the brain fixed-point sub-hypothermia control device plays an important role in reducing fatality rate and disability rate.

The invention provides a fluorescent RT-RAA (Reverse Transcription Recombinase Aid Amplification) primer for detecting MERS-CoV (Middle East Respiratory Syndrome Coronavirus), a fluorescent probe andapplication of the fluorescent RT-RAA primer and the fluorescent probe in detecting the MERS-CoV. The fluorescent RT-RAA primer and the fluorescent probe, disclosed by the invention, are capable of quickly and qualitatively detecting the MERS-CoV in a throat swab sample, detection can be carried out under the normal temperature of 39 DEG C, a diagnosis result can be obtained within 20 minutes, andthe detection time is greatly shortened; the fluorescent RT-RAA primer and the fluorescent probe are stronger in specificity and higher in sensitivity, quick diagnosis and whole-process monitoring onan epidemic situation can be completely met, and time is bought for early diagnosing and early treating the epidemic situation, reducing a case fatality rate and controlling the epidemic situation.

This invention provides one agent case by use of blood vessel and endothelium function to adjust its important praline carboxypeptidase gene mononucleotide polymorphism bit E112D gene and conception imperfect rate relationship on the channel to predict the incidence rate, wherein when the gene is of 112EE pure wild type, the incidence rate is low and when gene is of 112ED mixture or 112DD pure burst type the incidence rate is high. This agent case comprises the E112D polymorphism gene parting oligonucleotide and relative agents.

The invention relates to the field of biomedicine, and specifically relates to an enterovirus 71 antigen detection test strip (colloidal gold method) and a preparation method and application thereof. Enterovirus 71 can cause hand-foot-and-mouth disease, which has largegeneration proportion of severe infections (viral encephalitis, meningomyelitis virus and pulmonary edema), and a high death rate reaching 10%-25%. The test strip of the invention is used for rapid diagnosis of EV(enterovirus)71 infection. A virus separation and an RT-PCR (reverse transcription-polymerase chain reaction) are methods first used for EV71 antigen detection, but are not suitable for primary clinic usage due to defects of difficult operation and high costs, etc. The invention overcomes the above insufficiencies and provides a reagent, which is highly demanded in clinic detection, simply operated, suitable for various medical disease control sections, and capable of detecting EV71 antigens in human oropharyngeal swabs, bubble liquid, serum or excrement, and also provides the preparation method and application thereof. A technical scheme is as follows: a specimen is dropped on a sample pad, and the EV71 antigen wherein combines with a gold-labeled EV71 polyclonal antibody in a gold-labeled pad and migrates along a chromatography membrane. A detected line captures colloidal gold particles to form a red line visible to naked eyes, so as to realize detection of the EV71 antigen.

The invention relates to an optimum mass spectrometry model and a preparation method thereof for detecting the feature protein of breast cancer, belonging to the field of mass spectrometry detection technique. The invention is characterized in that eight up-regulated proteins and three lower-regulated proteins are screened from the blood serum to be used as the feature proteins; any two or more proteins of the eleven proteins are chosen so as to establish a blood serum feature protein mass spectrometry model of identification with two in a group for patients with breast cancer and normal people, and patients with benign breast disease, lymphatic metastasis of breast cancer and remote metastasis of breast cancer according to the mass-charge ratio m/z of each protein peak and the critical peak average value of the protein; the preparation method of the invention provides a foundation for further discovering new breast cancer biological marks. The method of the invention is better than any single detection method adopted currently for the detection of the breast cancer, and provides a non-invasive technique for the early detection and early treatment of the breast cancer, thus providing a new method for reducing the mortality of the breast cancer, improving the cure rate of the breast cancer and screening and examining the breast cancer for high-risk population further.

The invention provides an infectious disease monitoring and early warning method and device. The method comprises the steps: pre-constructing a preset feature set, wherein the preset feature set is determined according to the known infectious disease feature set; when a monitoring and early warning demand exists, obtaining a to-be-monitored electronic medical record first, and extracting the structured data and the post-structured data from the to-be-monitored electronic medical record; determining feature information of the to-be-monitored electronic medical record according to the structureddata and the post-structured data; comparing the feature information with feature information in a preset feature set, and determining the type of the infectious disease in the to-be-monitored electronic medical record; monitoring whether the number of unknown infectious diseases in the infectious disease types reaches a preset threshold value or not in real time; and when the number of unknown infectious diseases in the infectious disease types reaches the preset threshold value, determining that the unknown infectious diseases are to-be-confirmed newly-added infectious diseases so as to realize monitoring and early warning of the unknown infectious diseases. According to the invention, unknown infectious diseases can be discovered in time to reduce the infection probability of people, so that the case fatality rate is reduced.

The invention discloses a traditional Chinese medicine composition for treating acute stroke and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following raw medicines: senna leaf, giant knotweed rhizome, artificial bovine calculus powder, concretio silicea bambusae and trichosanthes fruit seed. The traditional Chinese medicine composition provided by the invention has the efficacy of dredging intestines and inducing resuscitation, is suitable for the symptoms of viscera and phlegm retention and viscera qi obstruction caused by the acute stroke, and is used for treating phlegm retention and viscera qi obstruction of yang and yin shutting syndromes of viscera caused by the stroke. The traditional Chinese medicine composition for treating patients suffering from acute stroke can improve clinical curative effect, reduce mortality and improve the life quality of patients; and the clinical application is safe without side effects.

The invention discloses a kit for testing H7N9 bird flu virus using real time fluorescence quantitative PCR, which is characterized in that the kit comprises: (1) a RNA extraction reagent, a reverse transcription reagent and a real time fluorescence quantitative PCR amplification reaction reagent; (2) two pairs of primers H7-F, H7-R and N9-F and N9-R for amplification of sample, and corresponding probes N7-probe and N9-probe. The kit for testing H7N9 bird flu virus nucleic acid of the present invention can test H7N9 bird flu virus by virus RNA extraction, reverse transcription and real time fluorescence quantitative PCR, and has the advantages of high accuracy, high sensitivity, high singularity and short detection window period, etc., and can provide early diagnosis and early treatment of epidemic disease and reduced case fatality rate and time for epidemic situation control.

A novel venous thromboembolism risk and prognosis prediction model is produced through the following steps: (1) establishing a new special personal risk scoring model for assessing the VTE of diabetology inpatients according to the age, the gender, the duration of diabetes, the blood sugar level, the body mass index, the blood pressure, uric acid and other diabetic patient VTE related risk factors; and (2) establishing a diabetolog VTE prognosis model according to the pulmonary embolism severity index score, the dual-energy CT lung perfusion imaging relative enhancement value, the pulmonary artery occlusion index, the C-response protein, the D-dimer and other indicators. The venous thromboembolism risk and prognosis prediction model for diabetology inpatients is clinically verified to be helpful for early diagnosis and judgment prognosis of diabetic patients with venous thromboembolism, so the disability rate and the case fatality rate are reduced.

The invention provides a traditional Chinese medicine composition and application thereof in prevention and treatment of viral pneumonia. According to the traditional Chinese medicine composition, 40-130 parts of fructus forsythiae, edible tulip, honeysuckle, scutellaria baicalensis and folium isatidis are used as basic components, and 50-110 parts of a qi-tonifying yin-nourishing component, 20-50parts of a spleen-tonifying circulation-assisting component, 15-50 parts of a phlegm-heat-clearing component, 14-50 parts of a phlegm-eliminating masses-resolving component and 20-50 parts of a lung-promoting, lung-moistening, lung-astringing and asthma-preventing component which accord with incompatibility of traditional Chinese medicines are matched. The traditional Chinese medicine compositionhas the effects of clearing away heat and toxic materials, dispelling wind and promoting exterior syndrome, relieving cough and reducing sputum and tonifying qi and yin, is suitable for treating thenovel coronavirus pneumonia, can effectively relieve symptoms of patients with the novel coronavirus pneumonia and improve prognosis, reduces the diseaseseverity-causing rate and the case fatality rate, and is clear and remarkable in curative effect.

The invention discloses a feed for preventing fish infectious hematopoietic necrosis and a preparation method thereof. The feed is prepared from the following raw materials: pumpkin powder, sorghum, barley, couch grass root, bran, bitter gourd, mung bean flour, lotus root starch, sweet potato powder, kelp powder, celery bran, black sesame bran, dried orange peel, lotus leaf and trace-element premix. The preparation method comprises the following steps: breaking, proportioning and granulating. The feed disclosed by the invention has the beneficial effects that the feed, which contains traditional Chinese medicine additives having functions of benefiting qi and nourishing blood, detoxifying and dredging collaterals, can be used for dredging collaterals, detoxifying, promoting normal generation of qi and blood, and achieving a remarkable curative effect on preventing fish infectious hematopoietic necrosis, and the feed can be used for controlling diseases timely and reducing the fatality rate; and meanwhile, the feed is low in medicine residue and cost, and suitable for application in large area and market popularization.

The invention relates to the technical field of feeds, and particularly discloses a feed additive and a piglet feed comprising the same. The feed additive disclosed by the invention is prepared from Chinese herbal medicines of herba portulacae, cactus and astragalus membranaceus by virtue of mixing according to a certain proportion. According to the feed additive disclosed by the invention, the case fatality rate of piglets can be reduced, and the piglet immunity is improved. The feed additive is added in the piglet feed, so that the growth of the piglets can be promoted, the average daily feed intake and the feed conversion ratio of the weaned piglet are increased, the feed efficiency is improved, and the economic benefit of piglet culturing is increased.

A sublow-temp cerebral protecting and therapeutic apparatus with semiconductor refrigeration is composed of a point-type temp sensor arranged in blood vessel, a constant-temp device for outputting sublow-temp perfusion and delivering it via blood vessel into cerebral region, a controller for the closed-loop control to the temp of perfusion, and a power supply. It can decrease the complications.

The invention discloses primers for detecting H7N9 avian influenza virus by using real-time fluorescence quantitative PCR. The primers include: (1) primers and a probe which are used for detecting avian influenza virus envelope hemagglutinin H7; and (2) primers and a probe which are used for detecting H7N9 avian influenza virus neuraminidase N9. By virtue of the primers disclosed by the invention, H7N9 avian influenza virus can be detected through the extraction of the virus RNA, reverse transcription and real-time fluorescence quantitative PCR. The primers and the method, disclosed by the invention, have the advantages of high accuracy, high sensitivity, high specificity and short detection window phase and can be used for buying more time for early diagnosis, early treatment, reduction of case fatality rate and epidemic situation control.

The invention discloses a feed special for newly-hatched ducklings capable of achieving nutrient balance and low fatality rate. The feed is prepared from, by weight, 20-50 parts of silkworm chrysalis meal, 5-15 parts of rye bran, 8-16 parts of cottonseed cake, 10-18 parts of cornstalk powder, 10-20 parts of cabbage caterpillar dry powder, 5-12 parts of water hyacinth dry powder, 2-6 parts of rice flour, 2-7 parts of doederlein spikemoss herb, 1-2 parts of gravel, 0.1-0.6 part of yeast protein meal, 1-3 parts of fructooligosaccharide, 0.5-1.5 parts of choline chloride, 0.1-0.4 part of vitamin, 0.01-0.06 part of high-temperature-resisting phytase, 2-5 parts of granulesten oil, 1-2 parts of sodium carboxymethylcellulose and 2-7 parts of modified soya bean lecithin. The feed can meet the requirement of meat ducklings 5-20 days old for nutrients, digestive utilization ratio is high, nutrient balance is achieved, and fatality rate can be reduced.

The invention discloses a suckling pig and piggy feed for preventing diarrhoea and a preparation method thereof. The feed consists of the raw materials in parts by weight: 200-300 parts of maize flour, 150-200 parts of wheat bran, 100-150 parts of millet flour, 70-90 parts of maize germs, 70-80 parts of whey powder, 50-70 parts of small fish and shrimps, 10-20 parts of lard, 20-30 parts of hedera helix stems, 20-30 parts of musa basjoo stems and leaves, 10-20 parts of cattail stems and leaves, 30-40 parts of malt flour, 7-9 parts of black sesame seeds, 4-6 parts of fennel seeds, 15-20 parts of cannabis meal, 10-15 parts of flax meal, 2-3 parts of ginger, 1-2 parts of sweetberry jointfir , 3-4 parts of spanishneedles herbs, 2-3 parts of plantain herbs, 1-2 parts of agaricus blazei, and 15-20 parts of attractants. The feed disclosed by the invention can well prevent the disease of the diarrhoea for suckling pigs and piggies, treat the suckling pigs and the piggies with the disease of the diarrhoea, can alleviate the state of an illness, and reduce the case fatality rate; at the same time, the feed can promote the suckling pigs and the piggies to grow and gain weight stably, so that the economic benefits of breading the suckling pigs and the piggies are improved.