737 results about "Diagnosis treatment" patented technology

A method of providing diagnosis capability, diagnosis of the effects of treatment or diagnosis of distinctive capabilities of a test subject, the method can comprise the steps of: (a) carrying out a series of tests on a group of subjects of at least two modal measures, the modal measures comprising brain-body function, brain structure, neuropsychological, personality, genetics, personal history, performance and behaviour; and (b) examining the inter-relationships between the modal measures to output an analysis of the inter-relationships of two or more measures of the tests results of the group of subjects.

The present invention relates to novel colon or colon cancer related polynucleotides and the polypeptides encoded by these polynucleotides herein collectively known as "colon or colon cancer antigens," and the use of such colon or colon cancer antigens for detecting disorders of the colon, particularly the presence of colon cancer and colon cancer metastases. More specifically, isolated colon or colon cancer associated nucleic acid molecules are provided encoding novel colon or colon cancer associated polypeptides. Novel colon or colon cancer polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human colon or colon cancer associated polynucleotides and / or polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and / or prognosing disorders related to the colon, including colon cancer, and therapeutic methods for treating such disorders. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and / or compositions for inhibiting the production and function of the polypeptides of the present invention.

Disclosed are methods for detecting, diagnosing, treating and preventing non-small cell lung cancer using differentially expressed genes. Furthermore, novel human genes, whose expression is elevated in non-small cell lung cancer compared to non-cancerous tissues, are provided. Also disclosed are agents for treating and preventing non-small cell lung cancer as well as methods for identifying further compounds for treating and preventing non-small cell lung cancer.

Systems and methods are provided for collecting, preparing, and / or analyzing a biological sample. A sample collection site may be utilized with one or more sample processing device. The sample processing device may be configured to accept a sample from a subject. The sample processing device may perform one or more sample preparation step and / or chemical reaction involving the sample. Data related to the sample may be sent from the device to a laboratory. The laboratory may be a certified laboratory that may generate a report that is transmitted to a health care professional. The health care professional may rely on the report for diagnosing, treating, and / or preventing a disease in the subject.

The present invention provides improved methods and systems for diagnosis, prevention, and treatment of a bone related condition such as osteoporosis. The present invention integrates bone mass measurement techniques with various preventive and treatment measures to create a protocol for prevention and treatment of the bone related condition. In one embodiment, a medical practitioner treats bone mass degradation occurring in a patient by measuring a bone characteristic level in at least one of the patient's bones to yield a score, conducting a gait analysis to yield a gait characterization, measuring a bone mass marker concentration in at least one of the patient's body fluids to yield a bone marker level, and prescribing one or more therapies. Optionally, the treatment may include designating a future time to repeat the measurement of a bone characteristic level, the gait analysis, and the measurement of bone marker level.

A system and a method for managing patient treatment stores in the database a patient history for each patient including data related to observations, test results, diagnoses, treatment regimen(s) and a treatment plan associated with the patient. The treatment plan is administered to the patient and medical device operating data related to the tasks of the associated treatment regimen is stored in the database. A reminder is issued if a task associated with the treatment regimen is not completed on time and the effectiveness of the treatment regimen is evaluated based upon the data stored in the database so that only effective treatment regimens are retained in the system. The system performs treatment planning, treatment monitoring, hospital monitoring, healthcare insurance billing, patient billing, research and analysis support, supply chain management and personnel scheduling.

The invention provides methods for diagnosing, treating, or evaluating inflammatory and autoimmune diseases by sampling peripheral blood, serum, plasma, tissue, cerebrospinal fluid, or other bodily fluids from a human subject having a suspected diagnosis. The sample is analyzed for the presence and amount of certain cytokines, which provides the diagnosis, prognosis or evaluation of therapeutic response.

Systems and methods are provided for collecting, preparing, and / or analyzing a biological sample. A sample collection site may be utilized with one or more sample processing device. The sample processing device may be configured to accept a sample from a subject. The sample processing device may perform one or more sample preparation step and / or chemical reaction involving the sample. Data related to the sample may be sent from the device to a laboratory. The laboratory may be a certified laboratory that may generate a report that is transmitted to a health care professional. The health care professional may rely on the report for diagnosing, treating, and / or preventing a disease in the subject.

With an introducing catheter (A) accommodated by a diagnostic-therapeutic catheter (B), the necessity of a sheath is eliminated to render the diagnostic-therapeutic catheter (B) as large as the sheath. This enables a manipulator to fully treat a patient with the use of diagnostic-therapeutic catheter (E). With the elimination of the sheath, the diagnostic-therapeutic catheter (B) is directly inserted into tubular human organs (e.g., radial artery and brachial artery). Coaxially provided are inner and outer tubes 12, 13 with the diagnostic-therapeutic catheter (B) to have an annular space 14, at least a part of which forms a drug-releasable open end 15 exposed to a shaft portion 11. The outer tube 13 has a plurality of drug-releasable side holes 9 to release an anti-spasmodic drug toward a blood vessel through the drug-releasable open end 15.

The invention encompasses methods and devices for diagnosing, theranosing, or prognosing a condition in a patient by enriching a sample in rare cells or other particles. The devices can be a microfluidic device comprising an array of obstacles and one or more binding moieties. The devices and methods can allow for enrichment of cells based on size and affinity, recovery of cells or other particles in locations on the microfluidic device, release of cells or other particles from the microfluidic device, flow of sample through the microfluidic device, and retention of rare cells or other particles from a sample obtained from a patient having a condition.

A system integrates diagnostic, therapeutic, monitoring and other devices commonly found in a healthcare environment into a Hospital Information System (HIS) to improve the delivery of healthcare. The system uses intelligent, networked diagnostic, therapeutic, monitoring and other devices to provide device performance and availability information. A medical device management system includes a repository of patient medical records and a scheduling system for use in scheduling of a medical procedure for a particular patient. A configuration manager in bidirectional communication with a medical device automatically initiates pre-configuration of the medical device for use in the medical procedure using medical record information of the particular patient derived from the repository, in response to scheduling of the particular patient to receive the medical procedure.

Systems and methods which operate to identify interventional instruments and / or other objects in images are shown. Embodiments operate to extract relevant information regarding interventional instruments from a multi-dimensional volume for presenting the information to a user in near real-time with little or no user interaction. Objects may be identified by segmenting a multi-dimensional volume, identifying a putative object of interest in multiple multi-dimensional volume segments, and determining a position of the object of interest within the multi-dimensional volume using the putative object of interest segment identifications. Identification of objects of interest according to embodiments may be utilized to determine an image plane for use in displaying the objects within a generated image, to track the objects within the multi-dimensional volume, etc., such as for medical examination, interventional procedures, diagnosis treatment, and / or the like.

A diagnostic / treatment instrument such as a handpiece equipped with a dental treatment tool, etc. is provided with a light radiating unit that can distinctively detect a dental lesion, to facilitate the treatment of the lesion. A light source for emitting light that can distinctively detect the lesion is mounted near the head of the handpiece to which a diagnostic / treatment tool can be attached. The light emitted from the light source illuminates an area forward of the diagnostic / treatment tool. Alternatively, the light source comprises a plurality of light-emitting devices which are arranged around the periphery of the forward end of the handpiece head in such a manner as to encircle the diagnostic / treatment tool, and radiates light to illuminate the area forward of the diagnostic / treatment tool. When an oral cavity is illuminated with the light, a clinician can observe reflected fluorescent light by using a filtering function that passes the fluorescent light, and thus the clinician can perform the treatment while checking the lesion.

The present invention is a natural, cell-free tissue replacement that does not require difficult or extensive preparation made by washing tissue replacement in a solution including one or more sulfobetaines and an anionic surface-active detergent and washing the tissue replacement in serial solutions of the buffered salt to remove excess detergent. The natural, cell-free tissue replacement may be a nerve graft that supports axonal regeneration, guides the axons toward the distal nerve end and / or is immunologically tolerated. Other forms of the invention are a composition and kit prepared by the method of making a native, cell-free tissue replacement. The present invention may be modified for use in diagnostic, therapeutic, and prophylactic applications.

A remote command center for providing services to geographically dispersed hospitalized patients. A datastore accessible to the remote command center receives patient data from geographically dispersed hospitalized patients. Monitored data elements of geographically dispersed hospitalized patients are also received at the remote command center and stored in the datastore. A smart alert module generates and applies patient specific rules to selected data elements. If a patient-specific rule for a hospitalized patient has been contravened, an alert is issued from the remote command center. A patient care module displays selected data elements of the hospitalized patients at the remote command center. A decision support module applies decision support algorithms to selected data elements of a hospitalized patient and to user input to provide patient care advice. Patient care advice comprises a diagnosis, a method of treatment, and a laboratory protocol. The decision support module may also write orders for medication, laboratory protocols and surgical procedures.

The invention herein disclosed is related to epitopes useful in methods of diagnosing, treating, and preventing coeliac disease. Therapeutic compositions which comprise at least one epitope are provided.

Images and quantitative analytical data are displayed in an interactive manner to a user to facilitate efficient and effective diagnosis, treatment, and assessment of an abnormality or pathology. Images acquired over time, which may be acquired with scanners of various modalities, are registered, displayed in a single image, and comparatively quantified to provide historical analysis of a given abnormality or pathology. The historical images and quantitative data may then be analyzed to determine the effectiveness of an applied treatment and provide additional guidance for a to-be implemented treatment. The images may include anatomical images or functional images. The quantitative data may be displayed in an interactive tabular format or displayed graphically through histograms, charts, graphs, and the like.

A system and method for standardizing care in a hospital environment. Information concerning the latest care and practice standards for a given condition is provided to a decision support module. The decision support module comprises decision support algorithms that reflect a standardize guideline of practice for a particular medical condition. The general categories of cardiovascular, endocrinology, general, gastrointestinal, hematology, infectious diseases, neurology, pharmacology, pulmonary, renal, surgery, toxicology, trauma all have guidelines and practice standards associated with them. Patient data and user input are inputted to the decision support algorithm. The user may be prompted for user input, and an assessment is made of the patient so as provide patient care advice for the patient. Examples of patient care advice are a diagnosis, a method of treatment, and a laboratory protocol.

Compositions and methods for diagnosing, treating and / or preventing cancers characterized by CDH17 overexpression based on the detection of CDH17 or the use of CDH17 as a target for therapeutic intervention or prophylactic intervention are provided. Methods for diagnosing and / or monitoring liver cancers using the expressing of CDH17 involve detecting and / or quantitating the CDH17 protein or encoding nucleic acids (DNA or RNA) in a biological sample such as urine from the subject. Methods for treating liver cancers using CDH17 as a target and of sensitizing cells with aberrant expression of CDH17 have also been developed. The methods include suppression or knockdown of the expression of CDH17 by administering an effective amount of a CDH17 inhibitor.

The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and / or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.

The invention discloses a remote medical system. The system comprises a portable medical instrument which can be worn on the human body, hospital wireless communication equipment, a hospital medical server and a doctor diagnosis terminal, wherein the portable medical instrument is worn on the human body to acquire data of the human body, and sends the data to the hospital wireless communication equipment in a wireless communication mode; the hospital wireless communication equipment transmits the received data to the hospital medical server; and the hospital medical server sends the data to the doctor diagnosis terminal. The medical instrument and the hospital wireless communication equipment of the remote medical system are communicated in a wireless mode, so that users can receive remote diagnosis treatment. In addition, because the portable medical instrument can be worn on the human body, the user can exercise freely. Moreover, the remote medical system also achieves a medical network which connects a pharmacy terminal, an apparatus room terminal, an accounting center terminal, and the like so as to ensure that people remotely solve a series of problems of medical treatment, payment, and the like.

The portable handheld medical diagnostic tool incorporates camcorder technology and combines multiple diagnostic attachments commonly use by physicians and medical personnel. When attached with various portable instruments, it can be a powerful tool for teaching, diagnostics, therapy of illnesses by virtue of real-time video, audio and other sensory feed on the portable handheld medical diagnostic tool. Video, audio and sensory data can then be transfer to computers or other electronic systems for medical presentation and training or for medical diagnostics. This ability is presently not available.

The present invention relates to MHC-peptide complexes and uses thereof in the diagnosis of, treatment of or vaccination against a disease in an individual. More specifically the invention discloses MHC complexes comprising Mycobacterium tuberculosis antigenic peptides and uses there of.

The present invention relates to compositions and fusion proteins containing at least two Mycobacterium sp. antigens, and nucleic acids encoding such compositions and fusion proteins. The compositions of the invention increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection.

An improvement in a method for closed-chest, video-assisted diagnostic or surgical treatment of a patient is provided. The improvement comprises draping a video monitor with a transparent sterile surgical drape and positioning the draped monitor within the surgical field so that a surgeon can perform an internal surgical or diagnostic procedure and view it on the monitor to provide improved visual alignment for the surgeon. A flexible, sterile drape for covering the video monitor is disclosed. An apparatus for assisting the surgeon in performing closed-chest, video-assisted surgical or diagnostic treatment of a patient is disclosed which comprises a movable cabinet having an adjustable arm to which is affixed a video monitor that can be extended into the surgical field of an operating room to improve the visualization of the surgery performed by the surgeon. An improved operating table for assisting a surgeon in performing closed-chest, video-assisted surgical or diagnostic treatment of a patient is also disclosed along with endoscopic visualization apparatus and an improved design of a view scope that allows the doctor to get closer to a patient during the operation.

A method and system for integrating radiological and pathological information for cancer diagnosis, therapy selection, and monitoring is disclosed. A radiological image of a patient, such as a magnetic resonance (MR), computed tomography (CT), positron emission tomography (PET), or ultrasound image, is received. A location corresponding to each of one or more biopsy samples is determined in the at least one radiological image. An integrated display is used to display a histological image corresponding to the each biopsy samples, the radiological image, and the location corresponding to each biopsy samples in the radiological image. Pathological information and radiological information are integrated by combining features extracted from the histological images and the features extracted from the corresponding locations in the radiological image for cancer grading, prognosis prediction, and therapy selection.

Methods, kits and compounds are provided that relate to the diagnosis, treatment, and / or prevention of preeclampsia.

Disclosed are capsid-modified rAAV particles and expression vectors, as well as compositions and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and using novel capsid-protein-mutated particle or rAAV vector constructs in a variety of diagnostic and therapeutic applications including, inter alia, as delivery agents for diagnosis, treatment, or amelioration of one or more diseases, disorders, or dysfunctions of the mammalian eye. Also disclosed are methods for subretinal delivery of therapeutic gene constructs to mammalian photoreceptors and retinal pigment epithelial cells, as well as use of the disclosed compositions in the manufacture of medicaments for a variety of in vitro and / or in vivo applications including the treatment of a variety of inherited retinal diseases.

The present invention relates to peptides that bind with high specificity and which functionally interact with the transferrin receptor (“TfR”) and which may be used in making molecular vehicles that carry biomolecules across membranes, including, e.g., across the blood brain barrier or the gastrointestinal tract. TfR specific binding moieties may also be used alone or as components in specific molecules that target the transferrin / transferrin receptor transport system. The invention relates more specifically to VNAR single chain antibodies derived from nurse shark that bind to TfR, compounds and compositions comprising a TfR specific VNAR binding moiety, methods for preparing them, diagnostic and therapeutic methods of use in vitro or in vivo, e.g., to diagnose, treat and / or prevent a pathological condition, disorder or disease in which it is beneficial to deliver a heterologous biomolecule across the blood brain barrier by association with a TfR specific VNAR binding moiety. Other uses for TfR specific VNAR binding moieties of the invention include, e.g., regulating the interaction of iron-charged transferrin with TfR (receptor cycling or cell surface presentation), such as may be therapeutic in treatment of certain cancer cells and tumors of various tissue types.