96 results about "Brachial artery" patented technology

Provided herein are methods and apparatus for stroke volume determination by bioimpedance from a patient's upper arm, or brachium, utilizing pulsations of the brachial artery contained therein. The apparatus includes two or more spaced apart alternating current flow electrodes positioned on the patient's arm proximate the brachial artery and two or more spaced apart voltage sensing electrodes positioned on the patient's arm proximate the brachial artery. The voltage sensing electrodes are positioned between the alternating current flow electrodes on the arm. An alternating current source is electrically connected to the alternating current flow electrodes and a voltmeter electrically is connected to the voltage sensing electrodes. A data input device is provided along with a processing unit in communication with the data input device, the alternating current source, alternating current flow electrodes, the voltmeter, and voltage sensing electrodes. The processing unit is capable of using data from the data input device and voltage sensing electrodes to calculate the stroke volume of the patient.

With an introducing catheter (A) accommodated by a diagnostic-therapeutic catheter (B), the necessity of a sheath is eliminated to render the diagnostic-therapeutic catheter (B) as large as the sheath. This enables a manipulator to fully treat a patient with the use of diagnostic-therapeutic catheter (E). With the elimination of the sheath, the diagnostic-therapeutic catheter (B) is directly inserted into tubular human organs (e.g., radial artery and brachial artery). Coaxially provided are inner and outer tubes 12, 13 with the diagnostic-therapeutic catheter (B) to have an annular space 14, at least a part of which forms a drug-releasable open end 15 exposed to a shaft portion 11. The outer tube 13 has a plurality of drug-releasable side holes 9 to release an anti-spasmodic drug toward a blood vessel through the drug-releasable open end 15.

The invention discloses a noninvasive continuous human body arterial blood pressure measuring method and equipment. The noninvasive continuous human body central arterial blood pressure measuring method comprises the steps as follows: calculating individualization parameters of a to-be-measured person artery blood vessel network model according to acquired pulse wave forms of radial arteries and brachial arteries; calculating radial artery blood pressure systolic pressure, diastolic pressure and blood pressure wave forms according to radial artery pulse wave speeds and artery blood vessel network parameters; calculating ascending aorta-radial artery transfer functions; further calculating central arterial blood pressure. The noninvasive continuous human body central arterial blood pressure measuring equipment consists of a signal processing and analyzing unit, a pulse wave and motion signal acquisition unit worn on the wrist as well as an electro-cardio and motion signal acquisition unit worn in front of the chest. According to the method and the equipment, electrocardiograms, the radial artery blood pressure, the central arterial blood pressure as well as motions and postures are monitored simultaneously, heart rate and electro-cardio morphological parameters are analyzed in various motion states, artery network model parameters and blood pressure parameters, particularly central arterial pressure wave form parameters, are analyzed, and the method and the equipment have great significance for prevention and control on cardiovascular diseases, particularly for prevention and control on high-risk diseases such as the hypertension, the coronary heart disease and the like.

Provided herein are methods and apparatus for stroke volume determination by bioimpedance from a patient's upper arm, or brachium, utilizing pulsations of the brachial artery contained therein. The apparatus includes two or more spaced apart alternating current flow electrodes positioned on the patient's arm proximate the brachial artery and two or more spaced apart voltage sensing electrodes positioned on the patient's arm proximate the brachial artery. The voltage sensing electrodes are positioned between the alternating current flow electrodes on the arm. An alternating current source is electrically connected to the alternating current flow electrodes and a voltmeter electrically is connected to the voltage sensing electrodes. A data input device is provided along with a processing unit in communication with the data input device, the alternating current source, alternating current flow electrodes, the voltmeter, and voltage sensing electrodes. The processing unit is capable of using data from the data input device and voltage sensing electrodes to calculate the stroke volume of the patient.

The invention provides a pulse wave acquisition device and a non-invasive blood pressure continuous beat-to-beat measuring system and method. The pulse wave acquisition device of an arm sleeve structure is adopted for the system to acquire brachial artery pulse wave signals and radial artery pulse wave signals, the system is low in power consumption, long in running time and more convenient and more comfortable to wear, and influences of inflation stimulus on an inflatable cuff on blood pressure measurement accuracy are avoided. A hemodynamic force detection analyzer in the system is connected with the pulse wave acquisition device wirelessly, and acquires, calculates and analyzes the brachial artery pulse wave signals and the radial artery pulse wave signals which are acquired by the pulse wave acquisition device; by combining the non-invasive blood pressure continuous beat-to-beat measuring method, non-invasive continuous beat-to-beat measurement of the blood pressure of a detected object is achieved, measurement operation is simplified, measurement accuracy is guaranteed, and the problem that because a non-invasive blood pressure measuring device and method in the prior art are tedious in operation and low in accuracy, continuous beat-to-beat measurement of blood pressure is hard to achieve is solved.

A “relaxoscope” (100) detects the degree of arterial endothelial function. Impairment of arterial endothelial function is an early event in atherosclerosis and correlates with the major risk factors for cardiovascular disease. An artery (115), such as the brachial artery (BA) is measured for diameter before and after several minutes of either vasoconstriction or vasorelaxafion. The change in arterial diameter is a measure of flow-mediated vasomodification (FMVM). The relaxoscope induces an artificial pulse (128) at a superficial radial artery (115) via a linear actuator (120). An ultrasonic Doppler stethoscope (130) detects this pulse 10-20 cm proximal to the point of pulse induction (125). The delay between pulse application and detection provides the pulse transit time (PTT). By measuring PTT before (160) and after arterial diameter change (170), FMVM may be measured based on the changes in PTT caused by changes in vessel caliber, smooth muscle tone and wall thickness.

The invention discloses a non-invasive central aortic blood pressure measuring method and device. The non-invasive central aortic blood pressure measuring method includes, according to a human artery network model based on viscous fluid mechanics, a method of calculating artery network model personalized parameters of a measured person through measured radial artery and brachial artery pulse wave signals and arm blood pressure values, a method of calculating an ascending aorta-radial artery transfer function and a method of calculating central arterial pressure waveforms through measured central arterial pressures. The non-invasive central aortic blood pressure continuous measuring device comprises a pulse wave signal processing and analysis unit and a radial artery and brachial artery pulse wave signal acquisition unit worn on a wrist. The method is different from an existing general transfer function method, the artery network model parameters of each person to be measured are measured and calculated and the artery network model parameters are numerical characteristics of the cardiovascular system states of the person to be measured with the calculated central arterial pressure waveforms, and the method and device has important meanings in prevention, curing and control of cardiovascular diseases, especially high-risk diseases, such as hypertensions and coronary heart diseases.

Methods are provided for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. Methods include partial or complete obstruction of the femoral or iliac arteries or the inferior vena cava, external compression of the iliac, femoral, or brachial arteries, placing the patient in a trendelenberg position, applying one or more compression members to the extremities, or removing portion(s) of cerebral spinal fluid. Partial obstruction of a vessel can be accomplished by a device comprising an elongate catheter and a distally mounted expandable member. The expandable member may comprise one or two balloons. Other medical devices, such as an angioplasty, stent, or atherectomy catheter, can be inserted distal the expandable member to provide additional therapeutic intervention.

The present invention relates to a device and a method for estimating central systolic blood pressure based on oscillometric signals from brachial artery by the use of a pressure cuff.

The invention relates to a body anti-corrosive preservation solution. The raw materials in percentage by weight of the preservation solution are: 10 to 40 percent of glycerol, 10 to 70 percent of ethanol, 1 to 20 percent of metacetonic acid, 0.1 to 20 percent of hexamethylene tetramine, 0.2 to 10 percent of 5-chloro-2-methyl-4-isothiazoline-3-ketone, 0.1 to 1 percent of peppermint oil and the balance being water. The application mode of the preservation solution comprises the following steps: the anti-corrosive preservation solution is injected into the digestive system of a body from the oral cavity or the nose and the throat of the body; the anti-corrosive preservation solution is injected through an aortic arch, a brachial artery or a femoral artery; and the anti-corrosive preservation solution can also be used to wipe the surface of a body by a tampon dipped in the preservation solution. The body anti-corrosive preservation solution is nontoxic and harmless to an operator and is easy to operate; moreover, the preservation solution has no influence on the environment and excellent anti-corrosive effects, and can ensure that a body maintains a natural state and softness in a natural state (at room temperature) for 5 to 12 days. In addition, the preservation solution can be used repeatedly and has a simple preparing method, easily obtained raw materials and strong maneuverability; moreover, the preservation solution has convenient practical application and is propitious to popularize and use.

Method to obtain continuous recording of the central arterial blood pressure waveform noninvasively utilizes dual (distal occlusion and proximal) brachial artery occlusion cuffs and dual external osculation. The distal arterial occlusion cuff eliminates venous stasis artifact and flow related gradient from aorta to the brachial artery. The proximal cuff measures, and delivers, dual external oscillation. The dual external oscillation allows measurement of the arterial compliance at a multitude of transmural pressure values during each cardiac cycle. Transmural pressure / arterial compliance and arterial pressure curves are subsequently reconstructed using dual external oscillation. The curves consist of two parts, rapid and slow parts, both at the frequency higher than the arterial pulse.

The invention discloses a vascular endothelial function detecting device based on fingertip temperature change. The vascular endothelial function detecting device is used in the field of medical instruments and comprises a device main machine with a main control circuit board and a function module led out from the device main machine and connected with the main control circuit board. The function module comprises a blood blocking module for controlling of brachial artery blood flowing, a temperature measuring module for measuring fingertip temperature change and an oxyhemoglobin saturation measuring module for measuring fingertip oxygen content of blood. A complex algorithm using the fingertip temperature change to deduce blood vessel diameter change rate is built in the main control circuit board, complex processes of a measuring method achieve automation and intelligentization, detecting cost and device price are reduced, most people can achieve self-management of cardiovascular health state at home, monitoring cost is effectively reduced, operation process is simplified, support can be provided for families and primary hospitals to conduct cardiovascular disease early prevention and diagnosis, and the device has great significance for early prevention of cardiovascular diseases.

An apparatus for measuring hydrodynamic parameters, especially for Augmentation Index (Aix) and / or Ejection Duration (ED), by non-invasive, cuff based occlusive, blood pressure measurement, which apparatus comprises occlusive, oscillometric automatic blood pressure meter and units. There can also be a method for non-invasive measurement of hemodynamic characteristics, especially AN and / or ED with an occlusive, pressure sensor cuff, placed on the brachial artery, wherein the apparatus according to the invention samples and analyzes and evaluates the signal flow of the oscillations of pulse waves using an unusual stepwise blood pressure measurement.

The Access guide catheter provides passage for therapeutic and diagnostic devices through vessels or conduits that return substantially in a direction from which they originated. One application is for delivery of therapeutic catheters to the carotid or cerebral arteries via access from the radial or brachial artery. The guide catheter enters the aorta from one of the great vessels, forms a closed loop in the aorta, and is directed back into a great vessel in an opposed direction. The distal portion of the guide catheter is advanced into the great vessel for support. Further support is attained by providing tension to the proximal shaft of the guide catheter. Flexibility of the guide catheter allows diagnostic angiograms to be performed prior to delivery of a therapeutic catheter or device.

The invention discloses a method for calculating heart and vessel functional parameters based on blood pressure and pulses of four limbs, and belongs to the technical field of biomechanics. The arterial blood pressure and pressure pulse waves of the four limbs are detected through a pulse wave sensor and a blood pressure sensor, and noninvasive synchronous detection on the heart function, the rete arteriosum hardenability and blood flow parameters of the heart and the vascular function is achieved. The method comprises the steps that blood pressure and pulse wave information of the brachial artery and ankle artery of the four limbs are firstly collected, a series of collected pulse waves are subjected to waveform averaging, and average waveforms of the brachial artery and ankle artery of the four limbs are obtained respectively. The relation between the pulse waves of the four limbs, a pressure gradient and blood flow is set up based on the waveform characteristic parameters acquired through waveform analysis and the nonlinear pulse wave theory, and then the heart and vessel functional parameters are calculated on the basis of the blood flow and four limb pulse and blood pressure data. According to the method, a frequent and noninvasive detecting means easy to operate, fast in output and low in price is provided for a heart and vessel system.

Provided herein are methods and apparatus for stroke volume determination by bioimpedance from a patient's upper arm, or brachium, or a patient's thorax, utilizing pulsations of the arteries contained therein. The apparatus includes two or more spaced apart alternating current flow electrodes positioned on the patient's arm or thorax and two or more spaced apart voltage sensing electrodes positioned on the patient's arm or thorax and in-between alternating current flow electrodes. The system and method utilizes the mean value of the second time-derivative of the cardiogenically induced impedance variation of the patient using the measured voltage from the voltage sensors in calculating the stroke volume of the patient.

The invention discloses a multifunctional diabetic foot detector, which comprises a multifunctional measuring tablet, the multifunctional measuring tablet, which serves as a sole, is connected to an inflatable sleeve vamp and an inflatable sleeve leg, so that the structure of a boot is formed, and a central processor is arranged on the lower surface of the multifunctional measuring tablet; and also comprised are a large-size toe sleeve, small-size toe sleeves, an inflatable brachial artery sleeve, and a transcutaneous oxygen pressure electrode. The multifunctional diabetic foot detector evaluates the peripheral circulation state of a patient with diabetic feet by measuring the dorsal artery of the foot, an ankle-brachial index, a toe-brachial index, transcutaneous oxygen pressure and foot temperature, evaluates the disease degree of the peripheral nerves of the patient by analyzing touch (pain) sense, the perspiration function and vibration sense and outputs the basal metabolic rate and plantar pressure distribution of the diabetic patient to serve as a subjective basis for the disease degree of the patient with diabetic feet, and the multifunctional diabetic foot detector can play a guiding role in precise treatment for patients with diabetic feet, and can also play an important role in the formulation of diabetic foot treatment solutions through cloud analysis data.

The invention discloses a method for estimating pulse pressure of a central aorta by using pressure pulse wave vibration signals of a tourniquet. The method comprises the steps of (I) providing an equation for estimating the pulse pressure of the central aorta; (II) measuring the pressure pulse wave vibration signals in the tourniquet, wherein the pressure pulse wave vibration signals comprise brachial artery systolic pressure, brachial artery diastolic pressure and the pressure pulse wave vibration signal waveforms in the tourniquet; (III) averaging the pressure pulse wave vibration signal waveforms and carrying out correction by using the systolic pressure and the diastolic pressure; (IV) analyzing the corrected pressure pulse wave vibration signal waveforms to obtain a plurality of characteristic signal values, wherein the characteristic signal values are independent estimating variables of the equation of the step (I); (V) substituting the numerical value of the estimating variables into the equation for estimating the pulse pressure of the central aorta to obtain the pulse pressure of the central aorta. The invention further provides a device for estimating the pulse pressure of the central aorta by using the pressure pulse wave vibration signals of the tourniquet by using the method.

The invention discloses a blood pressure measurement instrument, which comprises a finger sleeve, a cuff, a finger sleeve pressure sensor module, a cuff pressure sensor module, an air source module, an AD acquisition module, a processor module and the like, wherein the processor module comprises a linear inflation control part, an oscillation wave extraction part and a blood pressure parameter calculating part; the linear inflation control part is used for achieving various working modes of the finger sleeve or the cuff; and the oscillation wave extraction part is used for extracting a pressure oscillation wave signal acquired by the linear inflation control part. According to the blood pressure measurement instrument disclosed by the invention, blood pressure is measured by finger of a finger sleeve pressurizing method, without blocking the blood flow of brachial artery, so as to reduce influence, in particular influence in sleep, on a patient at the utmost; and the blood pressure is calibrated by virtue of a pulse wave blood pressure calibration technology (the cuff and the finger sleeve), so that measurement precision is improved.

A “relaxoscope” (100) detects the degree of arterial endothelial function. Impairment of arterial endothelial function is an early event in atherosclerosis and correlates with the major risk factors for cardiovascular disease. An artery (115), such as the brachial artery (BA) is measured for diameter before and after several minutes of either vasoconstriction or vasorelaxation. The change in arterial diameter is a measure of flow-mediated vasomodification (FMVM). The relaxoscope induces an artificial pulse (128) at a superficial radial artery (115) via a linear actuator (120). An ultrasonic Doppler stethoscope (130) detects this pulse 10-20 cm proximal to the point of pulse induction (125). The delay between pulse application and detection provides the pulse transit time (PTT). By measuring PTT before (160) and after arterial diameter change (170), FMVM may be measured based on the changes in PTT caused by changes in vessel caliber, smooth muscle tone and wall thickness.

The invention relates to a vascular function noninvasive detecting method and device, and belongs to the field of medical measuring methods and devices. The device is characterized in that the device is combined by a plurality of physiological signal collecting modules which consist of a temperature module, a blood pressure cuff module and a blood oxygen module. The method comprises the following steps: according to the change of parameters of a finger end temperature signal, a blood oxygen signal and a pulse wave signal when the brachial artery is blocked and released, the collected data by clinical tests, and a signal processing and statistical analysis method, establishing a quantitative evaluation formula of the condition of the vascular function, and evaluating the condition of the vascular function. The method and device has the advantages of no invasion, simplicity in operation, and convenience in clinical application. The invention also provides a corresponding hardware structure and corresponding software for the vascular function noninvasive detection.

A non-invasive detection system with a peripheral vascular blood flow adjusting function comprises a data collecting module, a filtering module, a feature point / section identification module, a data analysis module and a blood flow adjusting function evaluation module. Cuff downstream front arm or hand skin blood flow volume signals are continuously measured before and after blood flow of the brachial artery is blocked by means of the method that the unilateral upper arm is pressurized through a cuff, after the blood flow volume signals are subjected to filtering treatment, a stable blood flow section before compression of the cuff and a congestion section after relieving of cuff compression are identified, and the specific value of average blood flow volumes of the congestion section and the stable blood flow section is calculated to obtain the index of quantitative evaluation for the peripheral vascular blood flow adjusting function. The non-invasive effect is achieved in the whole operating process, the measuring time is short, through feature analysis for a time registration curve of the blood flow, a blood flow changing section dominated by peripheral vascular ischemic reaction is identified, the influence of the upstream artery endothelial function on peripheral blood flow signals can be effectively excluded to achieve targeted evaluation on the human body peripheral vascular blood flow adjusting function, and the pretty good application prospects are achieved.

A method and apparatus determine certain cardiac medical parameters that are useful is diagnosing cardiovascular disease. The apparatus is designed to carry out the method, which includes the steps of:(a) inflating a blood pressure cuff on the brachial artery to a supra-systolic pressure;(b) sensing a sequence of pressure pulse waveforms associated with the brachial artery that result from a plurality of cardiac ejection cycles;(c) averaging the waveforms to produce an average, representative waveform having an initial, incident wave portion and a reflected wave portion;(d) analyzing the representative waveform to determine a value of one or more cardiac medical parameters including the reflection wave ratio (RWR), the reflected wave transit time (RWTT), the maximum amplitude of the initial pressure wave (PS1), the maximum rise (slope) of the initial pressure wave (dp / dt), and / or the systolic ejection period (SEP); and(e) displaying the value of the medical parameter(s).

A method and apparatus are disclosed for determining certain cardiac medical parameters that are useful is diagnosing and treating cardiovascular disease. The apparatus is designed to carry out the method, which includes the steps of:(a) inflating a blood pressure cuff on the brachial artery to a supra-systolic pressure;(b) sensing a sequence of pressure pulse waveforms associated with the brachial artery that result from a plurality of cardiac ejection cycles;(c) averaging the waveforms to produce an average, representative waveform having an initial, incident wave portion and a reflected wave portion;(d) analyzing the representative waveform to determine a value of one or more cardiac medical parameters including the reflection wave ratio (RWR), the reflected wave transit time (RWTT), the maximum amplitude of the initial pressure wave (PS1), the maximum rise (slope) of the initial pressure wave (dp / dt), and / or the systolic ejection period (SEP); and(e) displaying the value of the medical parameter(s).

The invention relates to an endothelial cell function screening and diagnosing apparatus, which is equipment for screening and diagnosing endothelial cell functions and belongs to a medical instrument. The endothelial cell function screening and diagnosing apparatus comprises a peripheral circulation blood volume pulse wave digitalized detector, an automatic brachial artery pressurizing device, an embedded system with an expanded diagnosis function, an arithmetic module, a touch screen, a printing and expanding port and the like. The total endothelial cell function screening and diagnosing apparatus is a portable floor-mounted machine, and realizes spectrum analysis of peripheral circulation blood volume pulse waves under a flow-mediated condition, and a result of the spectrum analysis is excellently relevant to the endothelial cell functions. The endothelial cell function screening and diagnosing apparatus has the advantages that brachial artery blockage time is short, screening and diagnosing are simple, convenient and fast, a total process of recovering to a normal state from vasodilation caused by the flow-mediated condition can be observed, and the endothelial cell function screening and diagnosing apparatus is fine in reproduction, high in precision, low in cost and easy in popularization, and has the expanded diagnosis function.

Provided herein are methods and apparatus for stroke volume determination by bioimpedance from a patient's upper arm, or brachium, or a patient's thorax, utilizing pulsations of the arteries contained therein. The apparatus includes two or more spaced apart alternating current flow electrodes positioned on the patient's arm or thorax and two or more spaced apart voltage sensing electrodes positioned on the patient's arm or thorax and in-between alternating current flow electrodes. The system and method utilizes voltage sensed by the voltage sensing electrodes to calculate a cardiogenically induced impedance variation value of the patient, and to determine a stroke volume of the patient by multiplying the cardiogenicaly induced impedance variation value by a volume conductor VC and by a left ventricular ejection time TLVE.

The invention relates to a method for measuring blood pressure with electrical korotkoff sound measuring assisted sphygmomanometer. The method comprises detecting korotkoff sound at the brachial artery with korotkoff sound probe and transporting the sound to a korotkoff sound controller through cable; recording, processing, and judging the korotkoff sound with the korotkoff sound controller, suggesting fetching systolic pressure and diastolic pressure by emitting rhythmic call isochronous with the pulse of the detectors according to medical diagnosis requirement (the first sound of the korotkoff sound and the last sound of the changed korotkoff sound); and fetching the systolic pressure at the first rhythmic call and diastolic pressure at the last rhythmic call. The invention strictly adopts korotkoff sound as detecting target for blood pressure measurement, can accurately and reliably transform weak korotkoff sound into isochronous rhythmic call hearable for human, and helps gauger fetch blood pressure measure value directly from matched pressometer, thereby realizing real electronization for measuring blood pressure with korotkoff sound.

The invention discloses an ischemic preconditioning training sleeve belt device based on APP control. The ischemic preconditioning training sleeve belt device is characterized by comprising a sleevelet, a main airbag, an auxiliary airbag, a host, a pressure sensor, a heart rate sensor, a microphone sensor and a mobile terminal APP, the main airbag and the auxiliary airbag are mutually parallel and are both located in the sleevelet, and when the sleeve belt device is worn on the human body big arm, the main airbag is located above the human body brachial artery. In the ischemic preconditioning training sleeve belt device based on the APP control, the auxiliary airbag and antiskid belt protrusions are added, and the error resulted from airbag deviation in the measurement process is effectively prevented; through the addition of electrode massage plasters, the human body can quickly receiver from a paralysis state, and the ischemic preconditioning training sleeve belt device has a certain healthcare function; meanwhile, the covered cloth of the sleeve belt has good breathability and antibacterial activity, and breeding of bacteria due to sweating is effectively avoided.

The invention discloses an electrical impedance detector for artery endothelial functions of arteries and a method, which belong to the technical field of medical instruments. The electrical impedance detector comprises a front arm upper electrode, a front arm lower electrode, a high-frequency low-amplitude constant-current-source generator, an alternating-current voltage detecting circuit, a signal amplifier, a filter circuit, an A / D (analog / digital) conversion circuit and a computer. The alternating-current voltage detecting circuit detects voltage change, analog voltage signals of alternating-current voltage are converted into digital signals by the amplifier, the filter circuit and the A / D conversion circuit, and the digital signals are inputted to the computer. An electrical impedance changing curve along with time and brachial artery blood flow-mediated dilation are calculated, and the curve and a brachial artery dilation analysis result are displayed on a display finally. Compared with the prior art, the method has the advantages that instruments are simple, cost is low, miniaturization is realized, popularization is easy, and market prospect is wide.