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Electrical impedance detector for artery endothelial functions of arteries and method

A technology of endothelial function and electrical impedance, applied in diagnostic recording/measurement, medical science, sensors, etc., can solve problems such as time-consuming, inconvenient to use in communities or families, and expensive instruments and equipment

Inactive Publication Date: 2012-07-11
DALIAN UNIV OF TECH +1
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  • Summary
  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

Ultrasonic measurement of brachial artery endothelial function is considered a "promising technology" by the American Heart Association, but using this method to detect changes in arterial diameter requires precise positioning of the arterial diameter, which is not only cumbersome and time-consuming, but also Related instruments and equipment are expensive, and it is not easy to promote to the community or simple use at home

Method used

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  • Electrical impedance detector for artery endothelial functions of arteries and method
  • Electrical impedance detector for artery endothelial functions of arteries and method
  • Electrical impedance detector for artery endothelial functions of arteries and method

Examples

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Embodiment Construction

[0052] Such as figure 1 As shown, place the electrodes on both ends of the forearm to be tested; image 3 The detection circuit and computer system shown collect, store and analyze detection signals.

[0053] In this embodiment, the platinum wire is used as the electrode, and the cuff attached to the conventional sphygmomanometer is used as the brachial artery pressure device.

[0054] First detect and record the forearm impedance Z of the human body at rest baseline ; Pressurize the brachial artery with the air cuff that comes with a conventional mercury sphygmomanometer, block the blood flow of the brachial artery for a certain period of time (usually about 5 minutes), and then release it. time curve, such as Figure 4 Shown; Calculate the minimum value Z of the curve min . Finally, calculate the maximum change rate FMD of electrical impedance according to formula (12) z .

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Abstract

The invention discloses an electrical impedance detector for artery endothelial functions of arteries and a method, which belong to the technical field of medical instruments. The electrical impedance detector comprises a front arm upper electrode, a front arm lower electrode, a high-frequency low-amplitude constant-current-source generator, an alternating-current voltage detecting circuit, a signal amplifier, a filter circuit, an A / D (analog / digital) conversion circuit and a computer. The alternating-current voltage detecting circuit detects voltage change, analog voltage signals of alternating-current voltage are converted into digital signals by the amplifier, the filter circuit and the A / D conversion circuit, and the digital signals are inputted to the computer. An electrical impedance changing curve along with time and brachial artery blood flow-mediated dilation are calculated, and the curve and a brachial artery dilation analysis result are displayed on a display finally. Compared with the prior art, the method has the advantages that instruments are simple, cost is low, miniaturization is realized, popularization is easy, and market prospect is wide.

Description

technical field [0001] The invention belongs to a medical detection method and an instrument, and relates to a non-invasive early diagnosis method for cardiovascular diseases, in particular to a non-invasive detection method and an instrument for vascular endothelial function. Background technique [0002] In recent years, the incidence, disability, recurrence and death of heart disease and cerebral apoplexy have increased sharply, and the annual direct treatment costs have also shown a sharp increase, which has caused a heavy burden on patients' families and society. A large number of studies have shown that atherosclerosis is one of the important reasons for the occurrence and development of cardiovascular and cerebrovascular diseases. Arterial endothelium, as a functional barrier between blood flow and vascular wall, not only maintains the integrity of vascular structure, but also regulates the growth of vascular cells, regulates anticoagulant and fibrinolytic systems, me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/053
Inventor 覃开蓉陈英
Owner DALIAN UNIV OF TECH
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