34 results about "Aorta aortic" patented technology

The invention discloses an ultrasonic imaging system and method based on a heart surface, a medium and a product, the system comprises an ultrasonic detection assembly and an imaging terminal which are in communication connection, an ultrasonic transducer is packaged at the head end of an attached ultrasonic probe in the ultrasonic detection assembly, and an acoustic window on the ultrasonic transducer is planar; the ultrasonic transducer is used for being attached to the surface of the heart or the aorta, and the plane of the ultrasonic transducer is parallel to the plane of the acoustic window; and the imaging terminal is used for generating a sound velocity mask pattern according to the reference ultrasonic image, determining echo time delay data according to the sound velocity mask pattern, synthesizing and reconstructing the radio frequency signal data according to the echo time delay data to obtain an ultrasonic image, performing motion compensation on the image sequence, performing multi-modal fusion on the ultrasonic image subjected to motion compensation, and obtaining a final ultrasonic image. The problem of acoustic interference of anatomical structures such as the chest wall and the esophagus in a traditional echocardiography technology is solved, and real-time and high-quality image support is provided for cardiac surgery.

Method for determining the position of windows in aortic endoprostheses, using images from preoperative CT computed tomography, wherein such endoprosthesis comprises a tubular sleeve (1) having a diameter slightly greater than the diameter of such aorta, on which one or more windows (2) must be made in correspondence with the centre of origin of a blood vessel branching from such aorta. The method comprises the following steps: a) on the axial image of such tomography, calculating the aortic arc of circle (AA) between the position (PB) of such centre of origin of the vessel with respect to a reference point (OA) taken on the circumference of the aorta, b) calculating a conversion parameter (P) dependent on the difference between the diameter of the aortic artery and that of the tubular sleeve (1), c) determining the position of the window (PF) on the prosthesis by calculating the arc of circle on the prosthesis (AM) between a reference point (OM) taken on the tubular sleeve (1), placed in juxtaposition to such reference point (OA) on the aorta (A), and such position (PF), by subtracting the value of such conversion parameter (P) from the value of the aortic arc of circle (AA).

The invention discloses an application of methylene blue in preparation of drugs for preventing and treating aortic dissection and aortic aneurysm, which proves that after methylene blue is orally taken in an aortic aneurysm mouse model, expansion of aortic diameter can be inhibited and occurrence rate of aortic dissection and aortic aneurysm can be reduced after methylene blue is given. Abnormal aorta dilatation of mice and disorder and fracture of elastic fibers caused by BAPN water drinking are improved. Therefore, the death rate of the BAPN-induced aortic dissection and aortic aneurysm mice can be reduced and the disease progress of the aortic dissection and aortic aneurysm can be delayed by giving the methylene blue, so that the expansion condition of the aorta of the mice is improved and the survival rate is increased.

Disclosed are a method for calculating blood flow and shear stress of aorta having a bicuspid aortic valve, readable medium storing the method and a medical device using the method. A method for calculating blood flow and shear stress of aorta having a bicuspid aortic valve, which is performed by an electronic device, the method comprises receiving characteristic values of a bicuspid aortic valve, and calculating blood flow per unit area and shear stress applied to the aorta in a bipolar coordinate system of governing equation.

According to an aspect of the present invention, there is provided a method for imaging vasa vasorum density of a vessel in the body such as coronary and carotid arteries and the aorta and thereby assessing the risk of adverse health outcomes for a patient, comprising administering a contrast agent to the patient; performing a contrast-enhanced CT scan to measure Hounsfield distribution and heterogeneity related to vasa vasorum density in and around the vessel wall of a patient; analyzing the data to determine a metric related to the density of the vasa vasorum; and recommending a diagnostic and / or therapeutic next step to the patient to prevent adverse health outcomes based at least in part on the metric related to the vasa vasorum density.

A vascular implant is provided for increasing the efficiency of blood flow through an aorta. The vascular implant includes a tubular shunt having a lumen for allowing blood to pass between an aorta and an inferior vena cava. An expandable reservoir is sized for placement in the inferior vena cava. The reservoir has a first region coupled to the tubular shunt and may include a second region formed with an exit port for allowing some blood to escape the reservoir into the inferior vena cava. The exit port reduces the possibility of stagnation in the reservoir. High pressure blood from the aorta temporarily passes through the tubular shunt and into the reservoir, such as during systole. When blood pressure reduces in the aorta, blood from the reservoir passes from the reservoir and through the shunt where it reenters the aorta, such as during diastole.

The invention discloses a CT aorta robustness three-dimensional segmentation method and device based on deep learning, and relates to the technical field of medical image processing, and the method comprises the steps: extracting an aorta slice sequence frame by frame; carrying out linear interpolation and thresholding on the extracted probability graph; setting the initial segmentation mask of the current slice as an initialization prompt of a medical video segmentation model with a memory mechanism; for the initial slice image, calling an initialized memory state function through a medical video segmentation model, generating an initial segmentation result of the initial slice, and encoding the initial segmentation result into an initial memory state; calling a propagation tracking state function to automatically predict an aorta original mask of a current slice through a medical video segmentation model by using memory states established in previous several frames of slices and a current slice image, and obtaining a prediction mask; and carrying out weighted fusion and three-dimensional reconstruction on the prediction mask and the preliminary segmentation mask. According to the method, full-automatic and robust three-dimensional segmentation of the CT aorta is realized.

The application discloses an in-vitro splicing method of a covered stent and the covered stent. The in-vitro splicing method of the covered stent comprises the following steps: constructing a digital model of an aortic vessel segment of a patient's affected part; generating a physical model of the aortic vessel segment of the patient's affected part according to the digital model; selecting a plurality of stent units and placing the plurality of stent units in the physical model; and connecting every two adjacent stent units to connect the plurality of stent units into an integral covered stent. The covered stent is formed by the in-vitro splicing method of the covered stent. The covered stent constructed by the application has higher conformity with the shape of the aorta of the patient's affected part, has better stability, is more in line with the physiological characteristics of human blood flow, and can be sent into the body as a whole when the covered stent is transported into the body, thereby reducing the operation in the body and improving the safety.

A robotic surgical method for repair of an infrarenal aortic aneurysm with an aneurysm sac in an aorta of a patient includes introducing at least one arm and a camera of a robotic surgical system into designated ports of the patient. Then, a graft is attached to a proximal wall of the aorta. The aneurysm sac is decompressed by inflating an intravascular balloon and initiating flow in an arteriovenous circuit. Anterior posterior walls of the aneurysm sac are stapled and the robotic incisions are closed. A method for inserting a conduit includes deploying an intimal umbrella, partially expanding an expandable graft, deploying an adventitial umbrella, and fully inflating the expandable stent.

An axially compressible bare stent for an aorta, formed by interleaving at least two wires having different diameters, i.e., a first wire and a second wire, in an overlapping manner. In a natural release state, the bare stent has a metal coverage of at least 30%. The first wire has a diameter of 20-150 μm, and the second wire has a diameter of 150-600 μm. During the use in the treatment of aortic aneurysms and / or aortic dissection lesions, low liquid permeability and a strong radial support force are provided at a desired location in an aorta by means of the axial compressibility of the bare stent.

The invention provides a covered stent system for curing total aortic dissection, which comprises a main stent, a large crevasse plugging device and a non-clogging blood flow branch stent, the main stent is used for blocking the crevasse, the main stent comprises a main stent skeleton and a micropore covering film, the large crevasse plugging device is wrapped in the main stent, and the micropore covering film is arranged in the main stent skeleton. The microporous stent is used for supporting the structure of a lesion position with a large crevasse, and the microporous stent is used for enabling some small branch passages to be unblocked; however, if a large crevasse exists at a non-branch position, the micropore of the micropore stent still causes the expansion of the interlayer, and at the moment, a large crevasse plugging device needs to be used. According to the invention, full aorta continuous treatment is realized: the main stent is designed to cover the whole course of thoracico-abdominal aorta and can be connected with an implanted individualized thoracico-aorta stent system to form a complete treatment scheme of the full aorta.

The invention provides a wound first-aid aorta occlusion double-balloon device which is characterized in that the near end of an inner tube is connected with the far end of a first balloon; the far end of the inner tube penetrates through the second balloon and is connected with the near end of the first liquid connector; the outer wall of the inner tube is connected with the near end of the second balloon, and the outer wall of the inner tube is connected with the far end of the second balloon; the near end of the outer tube is connected with the near end of the second balloon, and the near end of the outer tube is communicated with the second balloon; the far end of the outer tube is connected with the near end of the second liquid connector; the outer pipe is sleeved outside the inner pipe; the first connector cover is used for covering the far end of the first liquid connector, and the second connector cover is used for covering the far end of the second liquid connector. According to the double-balloon device for trauma first aid aorta occlusion, bleeding at the far end of the aorta can be controlled after the first balloon and the second balloon are filled, and stage occlusion of blood flow in blood vessel cavities of the aorta I area and the aorta III area is achieved, so that the flow of blood flowing to the brain and the heart is increased.

The application discloses an aortic dissection identification model construction method and identification method and related devices, and relates to the technical field of artificial intelligence, and comprises the following steps: training a teacher network model by using an echocardiogram data set of non-aortic dissection containing a large number of data samples, so that the trained teacher network model has good generalization ability. The data samples in the echocardiogram data set of the aorta are respectively input into the trained teacher network model and a student network model, the model parameters of the student network model are adjusted according to the difference between the trained teacher network model and the student network model in a preset feature recognition result and the difference between the recognition result of the student network model and a label true value, the student network model can learn the generalization ability of the teacher network model, the student network model can be trained based on a small amount of aortic dissection data samples, and the accuracy of the student network model in identifying the aortic dissection can also be ensured.

A robotic surgical method for repairing a subrenal aortic aneurysm having an aneurysm sac in an aorta of a patient includes introducing at least one arm of a robotic surgical system and a camera into a specified portal of the patient. A graft is then attached to the proximal wall of the aorta. The aneurysm balloon is decompressed by inflating the intravascular balloon and inducing flow in the arteriovenous circuit. The anterior and posterior walls of the aneurysm sac are stapled and the robotic incision is closed. A method for inserting a tube includes deploying an intimal umbrella, partially expanding an expandable graft, deploying an outer membrane umbrella, and fully inflating the expandable stent.

A compliant stent implant is provided for deployment into a descending aorta to reduce the clinical impact of a hardened aorta. The compliant stent implant includes a tubular body extending between a proximal end and a distal end and including a proximal anchoring section terminating at the proximal end and a distal anchoring section terminating at the distal end. Each section is adapted to move from a restricted state to an expanded state. The treatment section is interposed between the proximal anchoring section and the distal anchoring section and is adapted to move from an undeployed state having a first volume to a deployed state having a second volume, where in the undeployed state, the treatment section has an undeployed diameter less than a restricted diameter of the distal anchoring section and the proximal anchoring section in the restricted state, and where in the deployed state, the treatment section has an undeployed diameter less than a restricted diameter of the distal anchoring section and the proximal anchoring section in the restricted state. And wherein the difference between the first volume and the second volume is sufficient to retain 20% to 70% of the volume of blood ejected during constriction.

The invention relates to an aorta three-dimensional model reconstruction method and device, and the method comprises the following steps: carrying out the preprocessing of an aorta scanning image, and obtaining an enhanced scanning image; global anatomical perception is carried out on the enhanced scanning image, and an anatomical topological structure of the aorta full view is obtained; performing local texture optimization on the anatomical topological structure to obtain a locally optimized aorta model; and based on the locally optimized aorta model, performing a post-processing pipeline of curved surface reconstruction and grid optimization to obtain an aorta three-dimensional model. According to the technical scheme, a cascade global-local feature collaborative learning framework is adopted, anatomical alignment of global features and local features is achieved, the segmentation precision of a true and false cavity interface is improved, and the feature drift problem of a traditional cascade model is solved; by means of a post-processing pipeline for curved surface reconstruction and grid optimization, more than 90% of stepped artifacts are eliminated, the grid does not need to be manually repaired, and the strict requirement of CFD simulation is met.

The application discloses a blood pressure calculation method and equipment based on cross-scale fluid-solid coupling and considering nonlinear biomechanical characteristics of an aorta, and the method comprises the following steps: establishing a three-dimensional ideal aorta geometric model; establishing a zero-dimensional heart lumped parameter model to simulate the process that the heart pumps blood to the aorta inlet through periodic contraction and diastole; establishing a zero-dimensional three-element Windkessel model of small arteries to simulate blood flow microcirculation of peripheral small arteries; establishing a blood vessel wall biomechanical model containing residual stress of the aorta wall and active contraction of smooth muscle cells to obtain a pressure-radius relationship of the aorta wall as a fluid wall boundary condition to simulate the change process of the aorta radius in blood circulation; and coupling the three-dimensional ideal geometric model of the aorta, the zero-dimensional heart lumped parameter model and the zero-dimensional three-element Windkessel model to construct a cross-scale fluid-solid coupling system of hemodynamics, and the blood pressure in the aorta is calculated through iterative solution.

The application discloses application of Danshen-Gegen vesicle-like nanoparticles and belongs to the technical field of biological medicine. The Danshen-Gegen vesicle-like nanoparticles (SPVLNs) are extracted and purified from Danshen-Gegen decoction liquid by using a differential super-high-speed centrifugation method. The SPVLNs have good blood compatibility. When the SPVLNs are applied to treating abdominal aortic aneurysm, the SPVLNs can obviously relieve thickening of a blood vessel wall, reduce infiltrative cells of an arterial media and an adventitia, improve reduction and fracture of elastic fibers of the blood vessel wall, increase stretchability of the elastic fibers of the blood vessel wall, reduce contents of tissue muscle fibers and collagen fibers, reduce a fibrosis degree of the collagen fibers, obviously improve pathological changes of a mouse abdominal aorta caused by Ang II, and are safe and non-toxic.

An occlusion assembly for occluding the aorta of a patient is presented. The occlusion assembly includes an elongate shaft of two separate extrusions to which an elastomeric balloon envelope is bonded to an end of each. A support wire extends through the elongates shaft and the balloon envelope. At the proximal end of the shaft the proximal end of the support wire is secured to a proximal hub to give the entire assembly sufficient stiffness to be advanced into the vasculature of the patient. The balloon envelope is pre-molded to have a reverse teardrop or “ice cream cone” like shape and will maintain that general shape throughout inflation to the fully inflated state. If the balloon envelope is over inflated, the balloon envelope will advance distally and proximally (lengthening) along the support wire without damage to the surrounding vessel.

This invention provides a vascular model capable of simulating various pathological conditions in the coronary arteries, as well as a catheter testing method and catheter training method using this model. [Solution] A vascular model that simulates a coronary artery, comprising an inlet portion 22 formed on the main body that simulates the aorta, and a passage portion 30 extending from the inlet portion 22 that simulates the coronary artery, wherein a part of the passage portion 30 is formed on a replaceable portion 23 that can be attached to and detached from the main body. The replaceable portion 23 may have a convex lesion simulation portion 40 on the inner surface of the passage portion 30, or it may have a stenosis simulation portion 41 in which the inner diameter of the passage portion 30 is smaller than the inner diameter of the inlet portion 22.

Systems and methods for partial aortic occlusion are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient, and a catheter controller unit that causes the device to expand and contract to restrict blood flow through the aorta. The system also may include sensors for measuring blood pressure distal and proximal to the expandable device. The system further may include non-transitory computer readable media having instructions stored thereon, wherein the instructions, when executed by a processor coupled to the sensors, cause the processor to estimate aortic blood flow based on the measured blood pressures and corresponding waveforms, compare the estimated aortic blood flow with a target aortic blood flow range, generate an alert if the estimated aortic blood flow falls outside the target aortic blood flow range, and cause the catheter controller unit to adjust expansion and contraction of the expandable device to adjust an amount of blood flow through the aorta if the estimated aortic blood flow falls outside the target aortic blood flow range.

The application discloses a kind of method, system and device for calculating aortic cross section axial and size, belong to medical detection technical field.The method for calculating aortic cross section axial and size is by reading aortic cross section original drawing and marking chart, picture information is data, then according to PCA algorithm principle calculation aortic cross section axial direction, finally linear interpolation is carried out to axial line, solve the problem of striding pixel point caused by traversing edge coordinate when pixel interval is larger, calculate the size of aortic cross section axial line.The application considers aortic cross section global pixel point simultaneously, constructs covariance matrix using the energy distribution of pixel point coordinates in each direction in two-dimensional space, and uses covariance matrix and stretches, rotates covariance matrix to decompose feature vector to determine the axial direction and size of aorta, realize the conversion from high dimension to low dimension of data to achieve the accurate calculation of aortic cross section axial direction and size.

Whether to deploy a cerebral embolic protection (CEP) device is determined by initially retrieving one or more image of at least part of an aorta. The image includes an aortic valve. The image is segmented to identify the aortic valve, an aortic arch, and a plurality of branching blood vessels downstream of the aortic valve. Plaque in a segment of the image at or adjacent the aortic valve is identified, and a vulnerability score associated with the plaque is generated. Dynamics of blood flow in the aortic arch and at least one of the plurality of branching blood vessels is evaluated. It is then determined whether a CEP device should be deployed at least partially based on the vulnerability score. A CEP device is selected at least partially based on the dynamics of blood flow in the aortic arch.

The invention relates to the technical field of medical instruments, in particular to an aortic cannula with controllability. Comprising a tube body including an insertion end; the first water bag is connected with the pipe body and surrounds the pipe body, and the space in the first water bag is independent of the space in the pipe body; the second water bag is connected with the pipe body and surrounds the pipe body, the space in the second water bag is independent of the space in the pipe body, and in the extending direction of the pipe body, the first water bag is close to the inserting end relative to the second water bag; wherein the insertion end and the first water bag are configured to be inserted into an incision, the first water bag is filled with water after being inserted into the incision, the pouch line is used for tightening the incision after the first water bag is inserted into the incision, the first water bag in the water filling state is close to the inner wall of the aorta under the action of blood pressure so as to seal the incision, and the second water bag is configured to be exposed outside the incision. The second water bag is filled with water after the first water bag is filled with water. The depth controllability, the fixing firmness and the sealing reliability of the aortic cannula are realized, and the surgical accident risk is reduced.

One or more systems, structures, and / or methods are provided. An aortic root repair system may include a first structure including a first tube, a ring extending circumferentially along the first tube and configured to be coupled to ventricular tissue of a patient, and a first plurality of protrusions, extending from the first tube. The first plurality of protrusions may include a first protrusion configured to be coupled to first aortal tissue of an aorta of the patient, and a second protrusion configured to be coupled to second aortal tissue of the aorta. The aortic root repair system may include a second structure including a second tube, and a second plurality of protrusions, extending from a first side of the second tube, including a third protrusion configured to be coupled to the first protrusion and the second protrusion.

This application provides a method, apparatus, device, medium, and program product for obtaining the aortic centerline, comprising: preprocessing a CTA image based on a pre-trained convolutional neural network algorithm to obtain target segmentation prediction results and trunk segmentation prediction results; preprocessing the CTA image based on a pre-trained convolutional neural network algorithm to obtain target segmentation prediction results and trunk segmentation prediction results for the target aorta; obtaining a set of vessel vertices and a first set of endpoints for vessel segments in the target aorta based on the vascular skeleton line of the target segmentation prediction results; extracting the aortic sinus endpoints from the first set of endpoints based on the trunk segmentation prediction results, and determining a second set of endpoints; extracting a second shortest path set from the first shortest path set based on the Dijkstra algorithm and the set of vessel vertices, and determining the second shortest path set as the aortic centerline to improve the efficiency of obtaining the aortic centerline.

The catheter assembly for slitting a dissection membrane of an aorta of a patient includes a first catheter configured to be inserted into a true lumen located on a first side of the dissection membrane a second catheter configured to be inserted into a false lumen located on a second side of the dissection membrane, and an electrically conductive wire electrically conductively joined to the first and the second catheters. The wire is further configured to be energized with electrical current such that the dissection membrane can be slit by the wire A method is also provided.

The application provides an aortic dissection rupture sealing device, which comprises an anchoring part, a hollow flow channel, and an intima around the rupture, so as to prevent the fluid communication between the true lumen of the aorta and the false lumen formed at the rupture; a stent, which is adjustably coupled to the anchoring part, has a connecting end and a free end, and at least the free end of the stent is located in a branch blood vessel; and the stent has a hollow structure in communication with the hollow flow channel and is supported in the branch blood vessel to communicate the true lumen and the branch blood vessel. The above scheme can avoid the continuous expansion of the false lumen caused by the incomplete sealing of the rupture and residual shunt, and at the same time, the blood supply of the blood vessel channel is retained to ensure the stability of the blood supply of the branch blood vessel, which is beneficial to meet the blood supply demand of the internal organs, spinal cord and the like supplied by the branch blood vessel.

The invention belongs to the field of gene protein function research, and particularly relates to application of an FSTL1 gene or protein in preparation of a medicine for preventing and / or intervening abdominal aortic aneurysm. It is found for the first time that the FSTL1 can reduce the occurrence rate of abdominal aortic aneurysm of mice, reduce the maximum diameter of the abdominal aorta of the mice and relieve the elastic fiber fracture degree of the abdominal aorta of the mice, and therefore the FSTL1 has the potential of serving as a medicine for preventing and / or intervening the abdominal aortic aneurysm.

The invention belongs to the technical field of medical instruments, and particularly relates to an ascending aorta covered stent with biomechanical property, which comprises a support skeleton, the inner side and the outer side of the support skeleton are both covered with films, the support skeleton is formed by spirally winding functional metal wires, the functional metal wires are formed by spirally winding composite wires, and the functional metal wires are wound by the composite wires. And the composite filament is formed by weaving a plurality of strands of filaments. In terms of overall performance, the large vessel covered stent can be highly synchronized with radial expansion / retraction, circumferential stretching, longitudinal displacement and slight torsion generated by the ascending aorta in the cardiac contraction and diastole period, and therefore natural physiological movement of the aorta is effectively simulated.