64 results about "Aorta aortic" patented technology

The invention discloses an artificial heart valve near-physiological pulsation fluid external evaluation device and method, and relates to the technical field of heart valve testing.The artificial heart valve near-physiological pulsation fluid external evaluation device comprises a supporting frame, a driving unit, a tested valve installation unit and an artery and peripheral loop unit, the driving unit provides power for liquid flowing, and the tested valve installation unit is used for fixing an artificial heart valve; and a liquid volume assembly and a resistance assembly of the artery and peripheral loop unit can simulate the compliance and resistance of aorta blood vessels and peripheral artery blood vessels, so that the pressure waveform simulation of the systemic circulation loop is more accurate. On the basis of the air cavity, the elastic corrugated pipes with different frequency responses are arranged, the compliance and rebound resilience of the aorta are simulated, a device for rapidly replacing the tested valve is designed, and the mechanical property of the simulated human body aorta is adjusted by adjusting the parameters such as the output frequency and the vibration amplitude of the driving unit; real pressure and flow waveforms under different physiological / pathological conditions are simulated, and a more accurate and convenient detection environment is realized.

The invention discloses an ultrasonic imaging system and method based on a heart surface, a medium and a product, the system comprises an ultrasonic detection assembly and an imaging terminal which are in communication connection, an ultrasonic transducer is packaged at the head end of an attached ultrasonic probe in the ultrasonic detection assembly, and an acoustic window on the ultrasonic transducer is planar; the ultrasonic transducer is used for being attached to the surface of the heart or the aorta, and the plane of the ultrasonic transducer is parallel to the plane of the acoustic window; and the imaging terminal is used for generating a sound velocity mask pattern according to the reference ultrasonic image, determining echo time delay data according to the sound velocity mask pattern, synthesizing and reconstructing the radio frequency signal data according to the echo time delay data to obtain an ultrasonic image, performing motion compensation on the image sequence, performing multi-modal fusion on the ultrasonic image subjected to motion compensation, and obtaining a final ultrasonic image. The problem of acoustic interference of anatomical structures such as the chest wall and the esophagus in a traditional echocardiography technology is solved, and real-time and high-quality image support is provided for cardiac surgery.

The application provides an aortic dissection rupture sealing device, which comprises a body having a hollow flow channel extending along the axial direction of the body, the hollow flow channel penetrating the rupture for conducting the true lumen of the aorta and the branch blood vessel, and the body being used for connecting a stent located in the branch blood vessel; and an anchoring part arranged on the body and surrounding the hollow flow channel, and anchored to the surrounding intima at the rupture, so as to prevent the fluid from conducting between the true lumen and the false lumen formed at the rupture. By using the above scheme, the rupture sealing effect can be improved, the continuous expansion of the false lumen caused by the incomplete rupture sealing and the residual liquid leakage can be avoided, and the blood supply stability of the branch blood vessel can be ensured, so that the blood supply demand of the internal organs, the spinal cord and the like supplied by the branch blood vessel can be met.

Method for determining the position of windows in aortic endoprostheses, using images from preoperative CT computed tomography, wherein such endoprosthesis comprises a tubular sleeve (1) having a diameter slightly greater than the diameter of such aorta, on which one or more windows (2) must be made in correspondence with the centre of origin of a blood vessel branching from such aorta. The method comprises the following steps: a) on the axial image of such tomography, calculating the aortic arc of circle (AA) between the position (PB) of such centre of origin of the vessel with respect to a reference point (OA) taken on the circumference of the aorta, b) calculating a conversion parameter (P) dependent on the difference between the diameter of the aortic artery and that of the tubular sleeve (1), c) determining the position of the window (PF) on the prosthesis by calculating the arc of circle on the prosthesis (AM) between a reference point (OM) taken on the tubular sleeve (1), placed in juxtaposition to such reference point (OA) on the aorta (A), and such position (PF), by subtracting the value of such conversion parameter (P) from the value of the aortic arc of circle (AA).

The application provides an aortic dissection rupture sealing device, which comprises an anchoring part, a hollow flow channel, and an intima around the rupture, so as to prevent the fluid communication between the true lumen of the aorta and the false lumen formed at the rupture; a stent, which is adjustably coupled to the anchoring part, has a connecting end and a free end, and at least the free end of the stent is located in a branch blood vessel; and the stent has a hollow structure in communication with the hollow flow channel and is supported in the branch blood vessel to communicate the true lumen and the branch blood vessel. The above scheme can avoid the continuous expansion of the false lumen caused by the incomplete sealing of the rupture and residual shunt, and at the same time, the blood supply of the blood vessel channel is retained to ensure the stability of the blood supply of the branch blood vessel, which is beneficial to meet the blood supply demand of the internal organs, spinal cord and the like supplied by the branch blood vessel.

The application provides an auxiliary identification method and system for aortic dissection, and the method comprises the following steps: acquiring chest cavity plain scan images of a user's aorta through a CT device, and identifying cross-sectional contour images of the aorta in each chest cavity plain scan image through an image edge recognition algorithm; identifying edge structure information of each cross-sectional contour image, and extracting image features of each cross-sectional contour image; identifying each abnormal image area and abnormal information thereof in each cross-sectional contour image, identifying the abnormal type and abnormal degree of each cross-sectional contour image based on the abnormal information of each abnormal image area, and obtaining auxiliary identification information of aortic dissection of the user through an aortic dissection analysis strategy, aortic dissection probability prediction and prediction reasons. The scheme can improve the auxiliary identification efficiency of aortic dissection in emergency.

The invention discloses an application of methylene blue in preparation of drugs for preventing and treating aortic dissection and aortic aneurysm, which proves that after methylene blue is orally taken in an aortic aneurysm mouse model, expansion of aortic diameter can be inhibited and occurrence rate of aortic dissection and aortic aneurysm can be reduced after methylene blue is given. Abnormal aorta dilatation of mice and disorder and fracture of elastic fibers caused by BAPN water drinking are improved. Therefore, the death rate of the BAPN-induced aortic dissection and aortic aneurysm mice can be reduced and the disease progress of the aortic dissection and aortic aneurysm can be delayed by giving the methylene blue, so that the expansion condition of the aorta of the mice is improved and the survival rate is increased.

An occlusion assembly for occluding the aorta of a patient is presented. The occlusion assembly includes an elongate shaft of two separate extrusions to which an elastomeric balloon envelope is bonded to an end of each. A support wire extends through the elongates shaft and the balloon envelope. At a distal end of the shaft, the support wire is provided with an atraumatic J-tip. At the proximal end of the shaft the proximal end of the support wire is secured to a proximal hub to give the entire assembly sufficient stiffness to be advanced into the vasculature of the patient. The balloon envelope is pre-molded to have a reverse teardrop or “ice cream cone” like shape and will maintain that general shape throughout inflation to the fully inflated state. If the balloon envelope is over inflated, the balloon envelope will advance distally and proximally (lengthening) along the support wire without damage to the surrounding vessel.

The invention relates to the technical field of medical image processing, and relates to an aortic dissection noninvasive blood flow velocity measurement method, system and device and a storage medium. The aortic dissection noninvasive blood flow velocity measurement method comprises the following steps: acquiring four-dimensional computed tomography angiography image data to be detected; analyzing the four-dimensional computed tomography angiography image data by using an optical flow method to obtain an aorta blood flow velocity field; analyzing the four-dimensional computed tomography angiography image data, segmenting an aorta image and extracting a center line of the aorta; determining the open area of each position of the aorta according to the aorta image and the center line of the aorta; and determining the instantaneous flow velocity of each position of the aorta according to the aorta blood flow velocity field and the overflowing area of each position of the aorta to obtain a blood flow velocity measurement result. According to the invention, the blood flow velocity of the aorta can be accurately identified.

Disclosed are a method for calculating blood flow and shear stress of aorta having a bicuspid aortic valve, readable medium storing the method and a medical device using the method. A method for calculating blood flow and shear stress of aorta having a bicuspid aortic valve, which is performed by an electronic device, the method comprises receiving characteristic values of a bicuspid aortic valve, and calculating blood flow per unit area and shear stress applied to the aorta in a bipolar coordinate system of governing equation.

The present disclosure generally relates to implantable medical devices, and, in some embodiments, to a prosthetic aortic implant. Such implantable devices may be useful in the treatment of acute aortic dissections (AADs). related systems and methods are also provided. In some embodiments, the prosthetic aortic implant comprises an expandable support structure and at least a first portion sized and configured to be positioned within an ascending portion of a native aorta of a subject. In some embodiments, the first portion comprises a non-porous layer and a porous layer. In some embodiments, the first portion is sized and configured to engage an aortic root of the native aorta. In some embodiments, the prosthetic aortic implant is designed and configured to engage with and / or receive an aortic valve implant.

According to an aspect of the present invention, there is provided a method for imaging vasa vasorum density of a vessel in the body such as coronary and carotid arteries and the aorta and thereby assessing the risk of adverse health outcomes for a patient, comprising administering a contrast agent to the patient; performing a contrast-enhanced CT scan to measure Hounsfield distribution and heterogeneity related to vasa vasorum density in and around the vessel wall of a patient; analyzing the data to determine a metric related to the density of the vasa vasorum; and recommending a diagnostic and / or therapeutic next step to the patient to prevent adverse health outcomes based at least in part on the metric related to the vasa vasorum density.

A vascular implant is provided for increasing the efficiency of blood flow through an aorta. The vascular implant includes a tubular shunt having a lumen for allowing blood to pass between an aorta and an inferior vena cava. An expandable reservoir is sized for placement in the inferior vena cava. The reservoir has a first region coupled to the tubular shunt and may include a second region formed with an exit port for allowing some blood to escape the reservoir into the inferior vena cava. The exit port reduces the possibility of stagnation in the reservoir. High pressure blood from the aorta temporarily passes through the tubular shunt and into the reservoir, such as during systole. When blood pressure reduces in the aorta, blood from the reservoir passes from the reservoir and through the shunt where it reenters the aorta, such as during diastole.

The invention discloses a CT aorta robustness three-dimensional segmentation method and device based on deep learning, and relates to the technical field of medical image processing, and the method comprises the steps: extracting an aorta slice sequence frame by frame; carrying out linear interpolation and thresholding on the extracted probability graph; setting the initial segmentation mask of the current slice as an initialization prompt of a medical video segmentation model with a memory mechanism; for the initial slice image, calling an initialized memory state function through a medical video segmentation model, generating an initial segmentation result of the initial slice, and encoding the initial segmentation result into an initial memory state; calling a propagation tracking state function to automatically predict an aorta original mask of a current slice through a medical video segmentation model by using memory states established in previous several frames of slices and a current slice image, and obtaining a prediction mask; and carrying out weighted fusion and three-dimensional reconstruction on the prediction mask and the preliminary segmentation mask. According to the method, full-automatic and robust three-dimensional segmentation of the CT aorta is realized.

To provide an aortic cannula for ex vivo organ care system.SOLUTION: An aortic cannula for use in an ex vivo organ care system is provided, comprising: a cannula body that comprises a fitting adapted to connect to an organ care system, and an aorta interface to contact an aorta; and a pivot arm strap operably connected to a pivot mount, wherein the pivot mount allows the pivot arm strap to uniformly contact the aorta to hold the aorta on the aorta interface.SELECTED DRAWING: Figure 1

The invention discloses application of salvia miltiorrhiza-kudzu vine root vesicle-like nanoparticles, and belongs to the technical field of biological medicines. Salvia miltiorrhiza-kudzu vine root vesicle-like nanoparticles (SPVLNs) are extracted and purified from a salvia miltiorrhiza-kudzu vine root decoction by adopting a differential ultra-high-speed centrifugation method, and the SPVLNs have good blood compatibility, so that when the SPVLNs are applied to treatment of abdominal aortic aneurysm, the SPVLNs can be used for treating abdominal aortic aneurysm, and the SPVLNs can be used for treating abdominal aortic aneurysm. The traditional Chinese medicine composition is capable of obviously relieving thickening of blood vessel walls, reducing infiltration cells of a middle artery membrane and an outer artery membrane, improving reduction and breakage of elastic fibers of the blood vessel walls, increasing extensibility of the elastic fibers of the blood vessel walls, reducing the content of tissue muscle fibers and collagenous fibers and reducing the fibrosis degree of the collagenous fibers; the pathological change, caused by Ang II, of the abdominal aorta of the mouse is obviously improved, and safety and non-toxicity are achieved.

The application discloses an in-vitro splicing method of a covered stent and the covered stent. The in-vitro splicing method of the covered stent comprises the following steps: constructing a digital model of an aortic vessel segment of a patient's affected part; generating a physical model of the aortic vessel segment of the patient's affected part according to the digital model; selecting a plurality of stent units and placing the plurality of stent units in the physical model; and connecting every two adjacent stent units to connect the plurality of stent units into an integral covered stent. The covered stent is formed by the in-vitro splicing method of the covered stent. The covered stent constructed by the application has higher conformity with the shape of the aorta of the patient's affected part, has better stability, is more in line with the physiological characteristics of human blood flow, and can be sent into the body as a whole when the covered stent is transported into the body, thereby reducing the operation in the body and improving the safety.

The present invention provides a ventricular assist blood pumping device, which relates to the field of medical device technology. The blood pumping device comprises: a pumping vessel, a pump, and a one-way valve; the pumping vessel is provided with an inlet and an outlet; the inlet is arranged in the left ventricle and / or left atrium, and the outlet is arranged in the aorta; the head end of the pumping vessel is implanted in the heart through minimally invasive surgery, and the end of the pumping vessel is connected to the pump; a one-way valve is provided in the pumping vessel, so that the outlet is closed and the inlet is open when the blood pumping device is drawing blood; and the inlet is closed and the outlet is open when blood is transfused; the blood pumping device uses the positive and negative pressures during blood transfusion and drawing to control the opening and closing of the inlet and outlet through the one-way valve, thereby achieving the function of pumping blood in the ventricle and / or atrium into the aorta, and the blood pumping device stops transfusion during blood drawing, and stops drawing blood during transfusion, and can generate pulsatile blood flow like a healthy heart, so that the patient has a normal pressure difference between systolic and diastolic blood pressure, maintaining healthy physiological functions.

A robotic surgical method for repair of an infrarenal aortic aneurysm with an aneurysm sac in an aorta of a patient includes introducing at least one arm and a camera of a robotic surgical system into designated ports of the patient. Then, a graft is attached to a proximal wall of the aorta. The aneurysm sac is decompressed by inflating an intravascular balloon and initiating flow in an arteriovenous circuit. Anterior posterior walls of the aneurysm sac are stapled and the robotic incisions are closed. A method for inserting a conduit includes deploying an intimal umbrella, partially expanding an expandable graft, deploying an adventitial umbrella, and fully inflating the expandable stent.

An axially compressible bare stent for an aorta, formed by interleaving at least two wires having different diameters, i.e., a first wire and a second wire, in an overlapping manner. In a natural release state, the bare stent has a metal coverage of at least 30%. The first wire has a diameter of 20-150 μm, and the second wire has a diameter of 150-600 μm. During the use in the treatment of aortic aneurysms and / or aortic dissection lesions, low liquid permeability and a strong radial support force are provided at a desired location in an aorta by means of the axial compressibility of the bare stent.

The invention provides a covered stent system for curing total aortic dissection, which comprises a main stent, a large crevasse plugging device and a non-clogging blood flow branch stent, the main stent is used for blocking the crevasse, the main stent comprises a main stent skeleton and a micropore covering film, the large crevasse plugging device is wrapped in the main stent, and the micropore covering film is arranged in the main stent skeleton. The microporous stent is used for supporting the structure of a lesion position with a large crevasse, and the microporous stent is used for enabling some small branch passages to be unblocked; however, if a large crevasse exists at a non-branch position, the micropore of the micropore stent still causes the expansion of the interlayer, and at the moment, a large crevasse plugging device needs to be used. According to the invention, full aorta continuous treatment is realized: the main stent is designed to cover the whole course of thoracico-abdominal aorta and can be connected with an implanted individualized thoracico-aorta stent system to form a complete treatment scheme of the full aorta.

The invention provides a wound first-aid aorta occlusion double-balloon device which is characterized in that the near end of an inner tube is connected with the far end of a first balloon; the far end of the inner tube penetrates through the second balloon and is connected with the near end of the first liquid connector; the outer wall of the inner tube is connected with the near end of the second balloon, and the outer wall of the inner tube is connected with the far end of the second balloon; the near end of the outer tube is connected with the near end of the second balloon, and the near end of the outer tube is communicated with the second balloon; the far end of the outer tube is connected with the near end of the second liquid connector; the outer pipe is sleeved outside the inner pipe; the first connector cover is used for covering the far end of the first liquid connector, and the second connector cover is used for covering the far end of the second liquid connector. According to the double-balloon device for trauma first aid aorta occlusion, bleeding at the far end of the aorta can be controlled after the first balloon and the second balloon are filled, and stage occlusion of blood flow in blood vessel cavities of the aorta I area and the aorta III area is achieved, so that the flow of blood flowing to the brain and the heart is increased.

The application relates to the technical field of medical image processing, and relates to an aortic dissection noninvasive blood flow velocity measurement method, system, device and storage medium; the aortic dissection noninvasive blood flow velocity measurement method comprises the following steps: acquiring four-dimensional computed tomography angiography image data to be detected; analyzing the four-dimensional computed tomography angiography image data by using an optical flow method to obtain an aortic blood flow velocity field; analyzing the four-dimensional computed tomography angiography image data, segmenting an aortic image and extracting a center line of the aorta; determining the flow area of each position of the aorta according to the aortic image and the center line of the aorta; determining the instantaneous flow velocity of each position of the aorta according to the aortic blood flow velocity field and the flow area of each position of the aorta, and obtaining a blood flow velocity measurement result. The application can accurately identify the blood flow velocity of the aorta.

The application discloses an aortic dissection identification model construction method and identification method and related devices, and relates to the technical field of artificial intelligence, and comprises the following steps: training a teacher network model by using an echocardiogram data set of non-aortic dissection containing a large number of data samples, so that the trained teacher network model has good generalization ability. The data samples in the echocardiogram data set of the aorta are respectively input into the trained teacher network model and a student network model, the model parameters of the student network model are adjusted according to the difference between the trained teacher network model and the student network model in a preset feature recognition result and the difference between the recognition result of the student network model and a label true value, the student network model can learn the generalization ability of the teacher network model, the student network model can be trained based on a small amount of aortic dissection data samples, and the accuracy of the student network model in identifying the aortic dissection can also be ensured.

34 ABSTRACT The invention relates to a catheter assembly for slitting a dissection membrane of an aorta of a patient which comprises an elongate first catheter (2), an elongate second catheter (4), and a cutting wire (6). The elongate first catheter (2) has a lumen (24) extending therethrough and a first catheter end portion (22) configured to be inserted into a lumen of an aorta of a patient. The first catheter end portion (22) defines a first direction (d1) and comprises an opening (26). The lumen (24) of the first catheter end portion (22) opens into an external space (A) via the opening (26). The elongate second catheter (4) is disposed movably within the lumen (24) of the first catheter (2) and has a second catheter end portion (42). The second catheter end portion (42) is movable relative to the first catheter (2) between a first state and a second state. When in the first state, the second catheter end portion (42) is disposed at least essentially within the lumen (24) of the first catheter (2). When in the second state, the second catheter end portion (42) extends through the opening (26) into the external space (A) outside of the first catheter (2). The second catheter end portion (42) is flexible and has a free end (44) which defines a free end direction (df) in dependence on a flexural state of the second catheter end portion (42). The cutting wire (6) extends through the lumen (24) of the first catheter (2) and is fixed to a fixation point (64) on the second catheter end portion (42). The cutting wire (6) is configured to be energized with electrical current. The configuration is such that when the second catheter end portion (42) is in the first state, the free end (44) assumes a first orientation relative to the first catheter end portion (22), and, when the second catheter end portion (42) is in the second state, the free end (44) can be moved via a manipulation of the cutting wire (6) into a second orientation relative to the first catheter end portion (22), wherein the second orientation differs from the first orientation. [Fig. 7a]

A robotic surgical method for repairing a subrenal aortic aneurysm having an aneurysm sac in an aorta of a patient includes introducing at least one arm of a robotic surgical system and a camera into a specified portal of the patient. A graft is then attached to the proximal wall of the aorta. The aneurysm balloon is decompressed by inflating the intravascular balloon and inducing flow in the arteriovenous circuit. The anterior and posterior walls of the aneurysm sac are stapled and the robotic incision is closed. A method for inserting a tube includes deploying an intimal umbrella, partially expanding an expandable graft, deploying an outer membrane umbrella, and fully inflating the expandable stent.

A compliant stent implant is provided for deployment into a descending aorta to reduce the clinical impact of a hardened aorta. The compliant stent implant includes a tubular body extending between a proximal end and a distal end and including a proximal anchoring section terminating at the proximal end and a distal anchoring section terminating at the distal end. Each section is adapted to move from a restricted state to an expanded state. The treatment section is interposed between the proximal anchoring section and the distal anchoring section and is adapted to move from an undeployed state having a first volume to a deployed state having a second volume, where in the undeployed state, the treatment section has an undeployed diameter less than a restricted diameter of the distal anchoring section and the proximal anchoring section in the restricted state, and where in the deployed state, the treatment section has an undeployed diameter less than a restricted diameter of the distal anchoring section and the proximal anchoring section in the restricted state. And wherein the difference between the first volume and the second volume is sufficient to retain 20% to 70% of the volume of blood ejected during constriction.

The invention relates to an aorta three-dimensional model reconstruction method and device, and the method comprises the following steps: carrying out the preprocessing of an aorta scanning image, and obtaining an enhanced scanning image; global anatomical perception is carried out on the enhanced scanning image, and an anatomical topological structure of the aorta full view is obtained; performing local texture optimization on the anatomical topological structure to obtain a locally optimized aorta model; and based on the locally optimized aorta model, performing a post-processing pipeline of curved surface reconstruction and grid optimization to obtain an aorta three-dimensional model. According to the technical scheme, a cascade global-local feature collaborative learning framework is adopted, anatomical alignment of global features and local features is achieved, the segmentation precision of a true and false cavity interface is improved, and the feature drift problem of a traditional cascade model is solved; by means of a post-processing pipeline for curved surface reconstruction and grid optimization, more than 90% of stepped artifacts are eliminated, the grid does not need to be manually repaired, and the strict requirement of CFD simulation is met.

The application discloses a blood pressure calculation method and equipment based on cross-scale fluid-solid coupling and considering nonlinear biomechanical characteristics of an aorta, and the method comprises the following steps: establishing a three-dimensional ideal aorta geometric model; establishing a zero-dimensional heart lumped parameter model to simulate the process that the heart pumps blood to the aorta inlet through periodic contraction and diastole; establishing a zero-dimensional three-element Windkessel model of small arteries to simulate blood flow microcirculation of peripheral small arteries; establishing a blood vessel wall biomechanical model containing residual stress of the aorta wall and active contraction of smooth muscle cells to obtain a pressure-radius relationship of the aorta wall as a fluid wall boundary condition to simulate the change process of the aorta radius in blood circulation; and coupling the three-dimensional ideal geometric model of the aorta, the zero-dimensional heart lumped parameter model and the zero-dimensional three-element Windkessel model to construct a cross-scale fluid-solid coupling system of hemodynamics, and the blood pressure in the aorta is calculated through iterative solution.

The application discloses application of Danshen-Gegen vesicle-like nanoparticles and belongs to the technical field of biological medicine. The Danshen-Gegen vesicle-like nanoparticles (SPVLNs) are extracted and purified from Danshen-Gegen decoction liquid by using a differential super-high-speed centrifugation method. The SPVLNs have good blood compatibility. When the SPVLNs are applied to treating abdominal aortic aneurysm, the SPVLNs can obviously relieve thickening of a blood vessel wall, reduce infiltrative cells of an arterial media and an adventitia, improve reduction and fracture of elastic fibers of the blood vessel wall, increase stretchability of the elastic fibers of the blood vessel wall, reduce contents of tissue muscle fibers and collagen fibers, reduce a fibrosis degree of the collagen fibers, obviously improve pathological changes of a mouse abdominal aorta caused by Ang II, and are safe and non-toxic.