Provided are
fibrous composites prepared by methods of the present invention, comprising oxides and biodegradable polymers, in which the fibers are made of
aerogel-like
oxide materials having nanometer-sized pores. The fibrous composition advantageously has, at least, the following characteristics: (i) a very high
nanoporous surface area, which also permits
nucleation of crystallites; (ii) mesoporous / macroporous interspacial networks between the fibers, providing high bioactivity and a high transport rate; (iii) macropores for natural one-like tissue growth; (iv) good mechanical properties for handling and for
implant support; and (v) biodegradability for
implant dissolution and time-variable mechanical properties. Further provided are methods for using the bioactive biodegradable
fibrous composites as osteogenic composite materials for
tissue engineering, tissue re-growth, bone implants, and bone repair, and / or for the delivery of drugs or therapeutic compounds.