108 results about "Aorta part" patented technology

The invention relates to the technical field of medical image processing, in particular to an aortic valve automatic segmentation method based on a multi-temporal CTA image. The method comprises the following steps: identifying a laminar flow dark area and a vortex bright area on a cross section of an aortic sinus area; according to the first feature size of the laminar flow dark area and the second feature size of the vortex bright area, the valve leaflet-sinus wall spacing is determined; determining a first deviation index according to the change trend of the valve leaflet-sinus wall spacing in the cardiac cycle; determining a second deviation index according to a difference characteristic between the CT value of the laminar flow dark area and the CT value of the eddy current bright area; if the first deviation index and the second deviation index both exceed the corresponding threshold values, judging that the data is in a to-be-corrected time phase; correcting the spacing by using the correction weight calculated by the second deviation index; and extracting key parameters of each time phase on the longitudinal section, and associating the corrected valve leaflet-sinus wall spacing to construct a valve three-dimensional dynamic model, thereby facilitating the three-dimensional dynamic model to output more accurate valve motion data.

The invention discloses application of lobetyolin in preparation of a medicine for treating atherosclerosis, and belongs to the field of biological medicine. The atherosclerosis comprises atherosclerosis induced by a high methionine diet. Through verification, IL-33 in aortic tissues of ApoE <- / -> mice with high methionine diet is remarkably increased, and the expression level of IL-33 in the aortic tissues of the mice is remarkably reduced compared with that of a model group after the mice are treated by lobetyolin. It is proved that lobetyolin has a positive regulation effect on treatment of atherosclerosis. Through molecular docking analysis, the binding energy between the lobetyolin and the IL-33 is-7.3 kcal / mol, which indicates that the IL-33 and the lobetyolin have good binding stability. The invention provides a new idea for clinical treatment of atherosclerosis.

A method of performing a neurovascular procedure includes providing an assembly including a guidewire having a guidewire hub, an access catheter having an access catheter hub, and a guide catheter having a guide catheter hub. The method includes coupling the guidewire hub to a first hub adapter, coupling the access catheter hub to a second hub adapter, and coupling the guide catheter hub to a third hub adapter. Each of the first hub adapter, the second hub adapter and the third hub adapter is movably carried by a support table. The method includes driving the assembly in response to movement of each of the first hub adapter, the second hub adapter and the third hub adapter along the support table until the assembly is positioned to achieve supra-aortic vessel access.

The invention discloses an ultrasonic imaging system and method based on a heart surface, a medium and a product, the system comprises an ultrasonic detection assembly and an imaging terminal which are in communication connection, an ultrasonic transducer is packaged at the head end of an attached ultrasonic probe in the ultrasonic detection assembly, and an acoustic window on the ultrasonic transducer is planar; the ultrasonic transducer is used for being attached to the surface of the heart or the aorta, and the plane of the ultrasonic transducer is parallel to the plane of the acoustic window; and the imaging terminal is used for generating a sound velocity mask pattern according to the reference ultrasonic image, determining echo time delay data according to the sound velocity mask pattern, synthesizing and reconstructing the radio frequency signal data according to the echo time delay data to obtain an ultrasonic image, performing motion compensation on the image sequence, performing multi-modal fusion on the ultrasonic image subjected to motion compensation, and obtaining a final ultrasonic image. The problem of acoustic interference of anatomical structures such as the chest wall and the esophagus in a traditional echocardiography technology is solved, and real-time and high-quality image support is provided for cardiac surgery.

The subject of the invention is a delivery system for delivering a self-expanding endoluminal prosthesis to the patient's ascending aorta and aortic valve, the system comprising: - an inner tube (33), extending along a longitudinal Y axis of the delivery system (100), from an atraumatic distal tip (27) to a handle (37); - a metal tube (32), slide-fitted on the inner tube (33), and extending from the internal space of the distal tip (27) to a handle (37); - an outer tubular catheter shaft (22) slide-fitted on the metal tube (32), the catheter shaft (22) is brought out from the handle (37) and is terminated by a capsule (20), containing inside the radially compressed on the metal tube (32), self-expanding endoluminal prosthesis (1) having defined construction and covered at least partially by a coating (16), - the capsule (20) has closed position when is closed by the tip (27) and has open position when the capsule (20) and the tip (27) are displaced relative to each other; wherein the distal part of the metal tube (32) is equipped with receiving means (41, 42) on which the distal locking means (7) of prosthesis (1) are removably embedded and blocked in the inner space of the tip (27) and the delivery system (100) comprises also removable holding means (45, 45') retaining the proximal locking means (9) of the prosthesis (1), so that when the capsule (20) is in its fully open position, the prosthesis (1) is still maintained partially compressed, holding its crimping length.

The retractor for thoracoabdominal aorta replacement comprises a clamping assembly connected with an operating bed, the upper half portion of the clamping assembly is connected with a first connecting rod through a first locking assembly, the other end of the connecting rod is connected with two symmetrically-arranged universal balls through a second locking assembly, the universal balls are connected with a second connecting rod, and the second connecting rod is connected with a second connecting rod. A plurality of first traction assemblies and a plurality of second traction assemblies are installed on the second connecting rod through third locking assemblies. The device can be installed at any position of an operating bed, the second connecting rod can rotate by 360 degrees through the universal ball, the device adapts to patients with different fatnesses, the mounting angle and the mounting position can be adjusted through various locking assemblies, the device further adapts to patients with different body types, the whole structure can be detached into single structures to be disinfected and maintained, and the device is very convenient to use.

The application discloses a multi-delivery-site asymmetric positioning cross-valve catheter, and particularly relates to the technical field of cross-valve catheters, which comprises an expansion piece, a guide sheath and movable pieces. The expansion piece is provided with through grooves penetrating through the peripheral wall, and the number of the through grooves is at least one; accordingly, the through grooves divide the expansion piece into at least two sub-pieces; one end of each of the sub-pieces is connected through a closed ring-shaped part, and the other end of each of the sub-pieces is fixed with a single movable piece; the number of the movable pieces is matched with the number of the sub-pieces; each of the sub-pieces is provided with an expansion part, and the expansion part comprises at least four mechanical sub-pieces; the head of the guide sheath is arranged in the hollow interior of the closed ring-shaped part, and the middle part of the guide sheath is provided with a hole through which a cross-valve guide wire passes. The cross-valve catheter pushes the tail pipe of the sub-piece, so that the mechanical sub-pieces have different expansion sizes, the outer sides of the mechanical sub-pieces are attached to the ascending aorta, the coaxiality of the distal end opening of the catheter and the expected cross-valve point is improved, and the catheter is stabilized.

The application provides an auxiliary identification method and system for aortic dissection, and the method comprises the following steps: acquiring chest cavity plain scan images of a user's aorta through a CT device, and identifying cross-sectional contour images of the aorta in each chest cavity plain scan image through an image edge recognition algorithm; identifying edge structure information of each cross-sectional contour image, and extracting image features of each cross-sectional contour image; identifying each abnormal image area and abnormal information thereof in each cross-sectional contour image, identifying the abnormal type and abnormal degree of each cross-sectional contour image based on the abnormal information of each abnormal image area, and obtaining auxiliary identification information of aortic dissection of the user through an aortic dissection analysis strategy, aortic dissection probability prediction and prediction reasons. The scheme can improve the auxiliary identification efficiency of aortic dissection in emergency.

Systems and apparatus are provided for using a non-invasively monitored uncalibrated pressure signal from a patient to compute cardiac output and other cardio-vascular parameters, thereby providing safe, effective, reliable and low cost monitoring of patient health. Wearable devices are disclosed that include a sensor array for obtaining patient data that is used to provide an estimate of aortic systolic blood pressure, cardiac output, and end-systolic elastance that may be determined without the need for a cuff.

The invention discloses an aorta covered stent and an aorta stent system, and belongs to the technical field of medical instruments.The aorta covered stent comprises a tubular covered film, end outer wave-shaped stents are arranged on the outer walls of the two ends of the tubular covered film, and an end inner wave-shaped stent is arranged on the inner wall of at least one end; the wave troughs of the end inner wave-shaped stent are fixedly connected with the end of the tubular covering film, the wave crests and the wave crests of the end outer wave-shaped stent are arranged in a staggered mode, and the connecting beams connecting the wave crests and the wave troughs are slidably connected to the end of the tubular covering film at intervals. The aorta stent system comprises a stent conveying system and an aorta covered stent. The stent conveying system comprises a conveying catheter and a stent conveyor. After the end part of the aorta covered stent is compressed, the wave crest of the wave-shaped stent in the end part can extend out of the port of the tubular covered stent to be hooked and loaded with a stent conveying system; after the aorta covered stent is released, the wave crests of the corrugated stent in the end part can be shrunk into the tubular covered stent, so that stimulation to aorta blood vessels is avoided.

Disclosed herein are related to a system, a method, and a non-transitory computer readable medium for simulating, predicting, or estimating, based on machine learning neural networks, wall stress of a body part. In one approach, a first neural network automatically detects features in multiple images of a body part. For example, the first neural network may detect, for each image, a lumen and a wall of an aorta. According to the detected features, a second neural network may simulate, estimate, or predict wall stress of the body part in response to pressure applied to the body part. For example, a model generator can generate a three-dimensional model of the body part according to the detected features in the multiple images, and the second neural network can simulate, estimate, or predict wall stress of the body part according to the three-dimensional model.

The percutaneous intervention type axial flow blood pump comprises an impeller assembly, a flexible shaft transmission assembly and a handle assembly, the impeller assembly and the handle assembly are connected through the flexible shaft transmission assembly, the flexible shaft transmission assembly comprises a flexible shaft, a transition sleeve and a protective sleeve, the transition sleeve is connected with a flow guide tail cone of the impeller assembly, and the protective sleeve is connected with the impeller assembly. One end of the protective sleeve is fixed to the inner wall of the transition sleeve, the other end of the protective sleeve is connected with the handle assembly, the handle assembly is provided with an in-vitro micro motor in transmission connection with one end of the flexible shaft, and the other end of the flexible shaft is connected with an impeller rotor of the impeller assembly. The impeller assembly and part of the flexible shaft transmission assembly of the axial flow blood pump are percutaneously implanted into the body of a patient, the handle assembly is located outside the body, and the impeller assembly is kept fixed in the descending aorta through an elastic support of the impeller assembly. The axial flow blood pump adopts an in-vitro micro motor and flexible shaft transmission mode, and the problems that the temperature rise of an axial flow blood pump with a built-in motor is too high, abrasion particles are separated out, and fault inspection is not convenient are solved.

The invention provides a guide-wire-free integrated balloon catheter system which comprises a balloon dilatation mechanism, a balloon catheter body and a balloon catheter body, the balloon dilatation mechanism comprises a first balloon, a second balloon and a balloon pushing rod, and the first balloon and the balloon pushing rod are arranged in a penetrating mode; the first balloon is used for blocking an aorta I region; the second balloon and the balloon pushing rod are arranged in a penetrating manner; and the second balloon is used for blocking an aorta III region. According to the technical scheme, the hemostasis and plugging effects are improved.

The present disclosure provides a method and an apparatus for assessing a physiological signal quality based on an IABP device, and relates to the technical field of medical instruments. The method includes: acquiring, in the operation process of an IABP device, physiological signal of a patient treated by the IABP device, where the physiological signal include an electrocardiographic signal and / or an arterial blood pressure signal; extracting signal parameter values of the physiological signal, where the signal parameter values include: a first kurtosis, a skewness, an effective signal ratio, a second kurtosis, and a dominant frequency; performing signal quality assessment on the physiological signal based on the signal parameter values; and implementing, based on the physiological signal, intra-aortic balloon counterpulsation in response to a signal quality assessment result represents that the signal quality of the physiological signal satisfies a preset signal quality requirement.

The present application belongs to the technical field of medical operation auxiliary, and particularly relates to a precise tension control method and system for aortic repair operation. By acquiring the edge information and repair displacement of the repair area, the present application can not only evaluate the feasibility of the repair operation, but also obtain multiple executable repair plans through simulation calculation, so that the doctor can pre-plan the best repair scheme before the operation is implemented, greatly improving the success rate and safety of the operation. At the same time, the tension parameters in the repair process can be monitored in real time during the operation, ensuring that the repair process is carried out within a safe range, preventing the repair area from being stretched or compressed excessively, avoiding surgical risks, and through precise control of tension and optimization of repair plans, the operation time is shortened, the operation efficiency is improved, and the postoperative recovery time and complication risk of the patient are reduced.

The internal leakage prevention structure comprises a plurality of separation blade single bodies arranged on the outer surface of the covered stent, each separation blade single body comprises a separation blade main body and a supporting wire, the separation blade main body is in a blade shape or a flipper shape, a roughening structure is arranged on the surface of the separation blade main body, and the supporting wire is arranged on the surface of the separation blade main body. One end of the support wire is connected with the catch main body, and the other end of the support wire is fixedly connected with the covered stent; a certain included angle is formed between the blocking piece single bodies and the side wall of the covered stent, part of the blocking piece single bodies are arranged around a pre-windowing hole of the covered stent, the rest of the blocking piece single bodies are arranged on the outer surface of the covered stent in a multi-position scattered mode, and the multiple blocking piece single bodies integrally form a breakwater-shaped structure. After the speed of leaked blood flow is reduced, thrombus is slowly generated, the leaked blood flow is naturally blocked, and therefore the probability of internal leakage is reduced.

A stent graft assembly including a main body and a branch coupling extending radially from the main body. A proximal end of the single branch stent device is configured to seal in an ascending portion of an aorta. The assembly further includes a modular stent device including a proximal end and a distal end. The proximal end of the modular stent graft is configured to couple to a distal end of the single branch stent device. The modular stent device includes a main body configured to couple inside the main body of the single branch stent device. The modular stent device includes a bypass gate and an artery leg. The modular stent device is configured to bifurcate at a bifurcation point from the main body to the bypass gate and the artery leg outside of and distal the distal end of the single branch stent device.

The present application relates to the technical field of medical image processing, and in particular to an aortic valve automatic segmentation method based on multi-phase CTA images. The method identifies the laminar flow dark area and the vortex light area on the cross section of the aortic sinus region; determines the leaflet-sinus wall distance according to the first characteristic size of the laminar flow dark area and the second characteristic size of the vortex light area; determines the first deviation index according to the change trend of the leaflet-sinus wall distance in the cardiac cycle; determines the second deviation index according to the difference characteristics between the CT value of the laminar flow dark area and the CT value of the vortex light area; if the first deviation index and the second deviation index both exceed the corresponding threshold, it is determined that the data is in the phase to be corrected; corrects the distance by using the correction weight calculated by the second deviation index; extracts the key parameters of each phase on the longitudinal section, associates the corrected leaflet-sinus wall distance to construct a three-dimensional dynamic model of the valve, and thus the three-dimensional dynamic model outputs more accurate valve motion data.

A vascular graft deployment tool can include a handle, an elongate mandrel positioned distal to the handle, a vascular graft at least partially disposed coaxially about the mandrel, a sheath assembly including a distal sheath portion and a proximal sheath portion, wherein the distal and proximal sheath portions are configured to constrain the vascular graft against the mandrel at an insertion diameter, and an actuator movable relative to the handle and engaging the sheath assembly, wherein operation of the actuator causes at least one of the distal and proximal sheath portions to longitudinally separate to free at least a portion of the vascular graft. Further, the vascular graft is expandable from an insertion state to a deployed state, and at least two suture envelopes are positioned between opposite end portions of the vascular graft.

The application discloses an artificial blood vessel stent with anticoagulation performance and a construction method thereof. After a pig heart aorta blood vessel is subjected to decellularization treatment, a pre-gel solution is prepared by compounding polyvinyl alcohol and methacrylated gelatin, a designed model is printed into a hollow tubular mold by using 3D printing, the pre-gel solution is injected into the mold to obtain an artificial blood vessel stent with controllable shape and size after cross-linking, and finally, the artificial blood vessel stent loaded with heparin is obtained by loading the heparin on the prepared stent. The material for preparing the pre-gel solution is selected, and the advantages of the material functions can be complemented. The decellularized matrix is beneficial to cell adhesion, proliferation and differentiation; the compounding of polyvinyl alcohol and methacrylated gelatin improves the mechanical properties of the stent and improves the cell adhesion. The heparin is loaded on the artificial blood vessel stent to improve the anticoagulation performance of the stent and prevent the formation of thrombus. The stent serves as an excellent biomedical material and has a wide application prospect in the fields of cardiovascular tissue engineering and biology.

The application belongs to the technical field of medical devices, and relates to a delivery system for a prosthetic valve, which comprises a guide wire, an ultrasonic probe and a processing module. The guide wire is used to build a delivery channel for a prosthetic valve to be delivered, and the end of the guide wire is provided with a guide wire head. The ultrasonic probe is arranged on the guide wire head, and is used to emit ultrasonic signals to the aorta and receive ultrasonic echo signals. The processing module is used to receive and respond to the ultrasonic echo signals, determine an aortic valve opening area according to the ultrasonic echo signals, output a first control instruction according to the aortic valve opening area and a current position of the guide wire head obtained in advance, and drive the guide wire head to move to the aortic valve opening area. The application reduces the difficulty of over-valve operation, shortens the operation time, avoids other surgical risks caused by long operation time, and has high safety.

The invention provides a training evaluation method and device for balloon blocking hemostasis, a medium and a product, and relates to the technical field of intelligent teaching. And respectively acquiring static pressure data reflecting the mechanical characteristics of the blood vessel wall and dynamic pressure data reflecting the hemodynamic characteristics. On the basis, the system combines specific preset bleeding case data, and determines hemostasis pressure ranges and partial hemostasis pressure ranges corresponding to different areas of the aorta under specific operation conditions through calculation. When a user operates, the system can call the matched pressure range standard according to the current real-time blocking position and the target operation combination parameter, and compares the collected real-time blocking pressure with the matched pressure range standard. According to the scheme, the technical problem that an existing simulation training system is difficult to adapt to complex fluid mechanics changes of a simulated person in different physiological states is solved.

Provided are an artificial intelligence AI-based simulation device and method for supporting procedure planning in transcatheter aortic valve implantation. The device receives patient-specific medical images, such as computed tomography data, and generates a three-dimensional (3D) model of the aortic root and native valve. An artificial valve is virtually inserted into the 3D model, and the virtual implantation model is automatically converted into mesh data suitable for Computational Fluid Dynamics (CFD) and Fluid-Structure Interaction (FSI) analysis. The processor performs CFD / FSI simulations to evaluate hemodynamic changes, structural stresses, and potential device-tissue interactions. Based on the analysis, the system outputs predicted risks of procedure-related complications (including coronary obstruction, annular rupture, paravalvular leakage, and valve deformation) and provides guideline data for selecting valve size, implantation depth, and insertion angle. The disclosed device and method enable accurate, patient-specific prediction and visualization, thereby assisting clinicians in establishing safe and optimized TAVI procedure plans.

The invention discloses a river network flood control situation studying and judging method and system based on blood vessel-nerve collaborative bionics. According to the method, a multi-source monitoring sensing network is constructed in a river network in a bionic mode to collect hydrological data in real time, the river network is divided into three levels of aorta, arteries and capillaries according to human body blood vessel grading characteristics, and a dynamic regulation and storage model is constructed in combination with an improved Saint-Venant equation set and a Manning formula. And calculating a basic conveying index, a dynamic buffer index, a structural stability index and an instantaneous risk pressure index. A comprehensive bearing capacity index is generated through a bearing capacity-pressure framework, five-level situation risk grading is achieved, and finally visual study, judgment and early warning are conducted based on a GIS platform. According to the invention, the accuracy and foresight of river network flood control regulation and control are improved.

The invention belongs to the technical field of medicine, and discloses a thoracic aorta in-situ fenestration and whole-course brain protection integrated device and method. According to the method, a bundling balloon is formed by a plurality of small balloons, the different small balloons are controlled to be inflated or shrunk under pressure relief, and the angle of a puncture needle is adjusted through the bundling balloon catheter. And the far-end protection umbrella covers the cluster balloon catheter and is used for preventing thrombus from escaping to the far end. According to the invention, the bundling balloon composed of a plurality of small balloons is designed, and the angle of the puncture needle is adjusted by controlling the different small balloons to expand by filling or shrink by releasing pressure, so that the time for an instrument to enter a membrane rupture window is greatly shortened, and the positioning accuracy of a membrane rupture point of the covered stent is improved; meanwhile, a far-end protective umbrella is arranged to prevent thrombus and other foreign matters from escaping to the far end.

The utility model provides an in-situ windowing membrane rupture device for a covered stent, which relates to the field of medical instruments and comprises an outer tube, a middle-layer positioning tube, an inner-layer positioning tube and a membrane rupture guide wire which are sequentially sleeved from outside to inside and can relatively axially slide two by two, an elastic expansion part is connected to the peripheral surface of the far-end section of the middle-layer positioning tube and has an expansion state of expanding in the radial direction to be spherical and a contraction state of contracting in the radial direction; the outer tube can axially slide relative to the middle-layer positioning tube, so that the elastic expansion part is accommodated or released in the outer tube; the far-end face of the inner-layer positioning pipe is provided with concave-convex positioning sawteeth facing the far-end direction. The aorta covered stent at least relieves the technical problem that in the prior art, when an aorta covered stent is subjected to in-situ windowing and membrane rupture, guide wire positioning is not accurate.

The application provides a split aortic regurgitation valve stent and artificial valve, the valve stent comprises a stent body and a positioning member, the positioning member is sleeved on the outer periphery of the stent body, one end of the positioning member is movably connected to one end of the stent body through a soft connection structure; the stent body is divided into an inflow end and an outflow end along the axial direction; the positioning member has a plurality of positioning rods connected in sequence, the middle part of the positioning rod is formed with a bent positioning foot towards the inflow end, the two ends of the positioning rod are connected to the outflow end through the soft connection structure and towards the outflow end, a threaded sleeve is arranged on the bent positioning foot, and the threaded sleeve is used for being connected with a traction thread in a threaded mode to control the opening angle of the positioning member in the implantation process through the traction thread. The opening angle of the positioning member is controllable, and the risk of sinus injury is relatively low.

The invention discloses a method and a system for predicting the mechanical property of a blood vessel and calcified plaque material. The method comprises the following steps: constructing a three-dimensional geometric model containing an aorta root blood vessel wall, an autologous valve and a calcified plaque; constructing a bracket geometric model actually implanted in the operation; using finite element analysis to simulate the implantation process of the stent, and obtaining the geometric morphology index of the simulated stent valve ring; based on the obtained geometrical morphology indexes of the stent valve ring, the material mechanical property with clinical value of the target patient is determined; obtaining material mechanical properties with clinical values of a plurality of target patients and corresponding clinical feature data thereof, and constructing a data set; based on the constructed data set, a nonlinear regression model is adopted to construct a prediction model of clinical features and material mechanical properties; and performing prediction by using the prediction model. By adopting the method and the system, the mechanical property of the individual material can be obtained noninvasively, and the mechanical property of the new patient material can be predicted by associating the mechanical property with the clinical characteristics.

The present disclosure relates to a stent for the full length of an aorta, a stent kit, and a stent delivery system. The stent is provided with a stent body and a cavity formed by means of enclosure of the stent body. The stent has a length of 200 mm-600 mm and an outer diameter gradually tapered from 60 mm-30 mm to 30 mm-10 mm; and the stent body is woven of at least two wires with different diameters and is configured to be compressible and extensible at any position in the axial direction of the stent in a released state, wherein a first wire has a diameter of 20 µm-150 µm, the second wire has a diameter of 150 µm-800 µm, and at least one branch stent fixing mechanism is arranged in the cavity.

This invention belongs to the field of medical devices and discloses a vascular rupture sealing device, including a sealing assembly and a driving assembly. The sealing assembly includes a first sealing part, a second sealing part, and an elastic sealing component. This invention enables the elastic sealing component to deform outwards when the first and second sealing parts compress it. This deformation causes the pressing part to extend outwards. The thickening reduces the rolling effect, allowing the pressing parts at both ends to move relative to each other and press against both sides of the aortic intima for sealing. Furthermore, the smaller diameter before deformation facilitates insertion into the rupture, making installation convenient, the structure simpler, and more effective.