The invention relates to a centrifugal combined indefinite chill cast-iron roller and a preparation method thereof, pertaining to steel rolling technical field. The chemical composition of a roll barrel is (weight percent): 3.2-3.8 C, 3.8-4.5 Ni, 1.2-1.8 Cr, 0.2-0.4 Mo, 0.2-0.5Cu, 1.0-1.8 Si, <0.8Mn, 0.10-0.30 Nb, 0.05-0.20 V, 0.05-0.20 Ti, 0.04-0.07Mg, 0.02-0.05 Y, 0.01-0.03 Sb, and the rest are Fe and unavoidable microimpurity. The invention employs a electric stove to produce a roller, and the roller is moulded with centrifugal casting method; the roller is characterized by high strength and hardness, good toughness, hardness uniformity and hardenability, excellent wear resistance and oxidation resistance and the anti-cold shock and heat shock properties are also good; no phenomena like breaking, peeling, crazing and steel sticking are in the operation process; the service performance is apparently better than high nickel-chrome indefinite chill cast-iron roller; the processing technique is simple, high-heat treatment is not needed and the production cost is low. The invented roll has the advantages that: the rolling mill operating rate is significantly improved, the production cost of mill bar is reduced, the surface quality of the mill bar is improved and the economic and social benefits are good.