1583 results about "Domestic animal" patented technology

A method and apparatus for measuring the physical characteristics of livestock animals such as cattle and hogs. The apparatus of the invention includes a plurality of strategically positioned cameras that are used to obtain data concerning volumetric, curvilinear (surface) and linear measurements of livestock animals such as cattle and hogs and the full carcasses thereof. In accordance with the method of the invention, the data is analyzed to provide information that substantially assists the commercial producer of livestock animals in producing a high-quality end-product for the consumer while adding profitability to the enterprise.

Compounds of Formula I-a

and all pharmaceutically-acceptable forms thereof, are described herein.

The variables R₁, R₂, R₃, Z₁, Q, and A shown in Formula I-a are defined herein. Pharmaceutical compositions containing one or more compounds of Formula I-a, or a pharmaceutically acceptable form of such compounds, and one or more pharmaceutically acceptable carriers, excipients, or diluents are provided herein. Methods of treating patients suffering from certain diseases responsive to inhibition of tyrosine kinase activity are also given. In certain embodiments the diseases are responsive to inhibition of Btk activity and/or B-cell proliferation. Such methods comprise administering to such patients an amount of a compound of Formula I-a effective to reduce signs or symptoms of the disease. These diseases include cancer, an autoimmune and/or inflammatory disease, or an acute inflammatory reaction. Thus methods of treatment include administering a sufficient amount of a compound or salt as provided herein to decrease the symptoms or slow the progression of these diseases. Other embodiments include methods of treating other animals, including livestock and domesticated companion animals, suffering from a disease responsive to inhibition of kinase activity. Methods of treatment include administering a compound of Formula I-a as a single active agent or administering a compound of Formula I-a in combination with one or more other therapeutic agent. A method for determining the presence of Btk in a sample, comprising contacting the sample with a compound or form thereof of Formula I-a under conditions that permit detection of Btk activity, detecting a level of Btk activity in the sample, and therefrom determining the presence or absence of Btk in the sample.

A bedding article for a domestic animal comprising an outer textile casing defining a geometric shape for supporting a domestic animal, an inner filling, and a microbe-inhibiting agent or property applied to at least one of the outer textile casing and the inner filling. The bedding article may be fabricated in various shapes, designs, and styles; e.g., rectangular, circular, elliptical, with or without upstanding side walls, etc. A process for applying the microbe-inhibiting agent or property to at least one on the outer textile casing and the inner filling is provided. Application methods include spraying, dipping, brushing, and rolling the microbe-inhibiting agent or property onto at least one of the outer textile casing and the inner filling. An alternative embodiment includes an outer textile casing defining a geometric shape for supporting a domestic animal, an inner filling, a lining therebetween, and a microbe-inhibiting agent or property applied to at least one of the outer textile casing, the inner lining, and the inner filling.

Compounds of Formula I

and all pharmaceutically acceptable forms thereof, are described herein.

The variables R₁, R₂, R₃, Z₂, and Q, shown in Formula I are defined herein.

Pharmaceutical compositions containing one or more compounds of Formula I, or a pharmaceutically acceptable form of such compounds, and one or more pharmaceutically acceptable carriers, excipients, or diluents are provided herein.

Methods of treating patients suffering from certain diseases responsive to inhibition of tyrosine kinase activity are also given. In certain embodiments the diseases are responsive to inhibition of Btk activity and/or B-cell proliferation. Such methods comprise administering to such patients an amount of a compound of Formula I effective to reduce signs or symptoms of the disease. These diseases include cancer, an autoimmune and/or inflammatory disease, or an acute inflammatory reaction. Thus methods of treatment include administering a sufficient amount of a compound or salt as provided herein to decrease the symptoms or slow the progression of these diseases.

Other embodiments include methods of treating other animals, including livestock and domesticated companion animals, suffering from a disease responsive to inhibition of kinase activity.

Methods of treatment include administering a compound of Formula I as a single active agent or administering a compound of Formula I in combination with one or more other therapeutic agent.

A method for determining the presence of Btk in a sample, comprising contacting the sample with a compound or form thereof of Formula I under conditions that permit detection of Btk activity, detecting a level of Btk activity in the sample, and therefrom determining the presence or absence of Btk in the sample.

Substituted biphenyl-4-carboxylic acid arylamide analogues capable of modulating receptor activity, are provided. Such ligands may be used to modulate receptor activity in vivo or in vitro, and are particularly useful in the treatment of pain and other conditions associated with receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for receptor localization studies.

Compounds of Formula (I) are provided, as are methods for their preparation. The variables W, X, Y, Z, R₅, R₈ and Ar in the above formula are defined herein. Such compounds may be used to modulate ligand binding to GABA_A receptorsin vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting GABA_A receptors (e.g., receptor localization studies).

A system and method for providing access to animal food utilizes identification tags on domestic animals, generally attached to a collar. The identification tag generates a signal that is detected by a receiver mounted on an enclosed food container. When the receiver detects a pre-selected acceptable signal from an animal, it activates a motor that causes a movable portion of the container to move to an open position. If the signal is no longer detected by the receiver, it activates the motor to move the movable portion of the container to a closed position. If the receiver detects a signal from an identification tag that is not one of the pre-selected signals, it activates the motor to move the movable portion of the container to a closed position.

The invention discloses an efficient mixing and feed feeding integrated machine. The efficient mixing and feed feeding integrated machine comprises a bottom plate, roller wheels and a charging hopper, wherein the downside of the charging hopper communicates with a crushing box, the crushing box communicates with a mixing box through a discharging pipe, the top of the mixing box is fixedly connected with a third driving motor through bolts, the third driving motor is connected with a second rotating shaft, the upper part of the second rotating shaft is fixedly connected with transverse stirring plates, and vertical stirring plates are arranged below the transverse stirring plates. According to the efficient mixing and feed feeding integrated machine, an extruding and pushing device is arranged and is used for carrying out repeated extrusion on feeds in the charging hopper, so that the blockage of the charging hopper is avoided, and the efficiency of crushing is increased; crushing rollers and crushing knife blades are arranged and are used for carrying out many-staged crushing on the feeds, so that the effect of crushing is improved; the vertical stirring plates are arranged, so that the feeds are thoroughly mixed, the uniformity and fineness of feed are improved, and the absorption of domestic animals is facilitated; and fan-shaped scrapers and spray nozzles which are distributed along circumference are arranged, so that discharging is facilitated, and feed residue is avoided.

A topical insect repellent with extended duration of protection was obtained from mixtures of molecules based on two or more volatile repellent organic molecular species occurring naturally on the human skin surface. The novel repellent comprises mixtures of lower, intermediate, and higher volatility organic molecules. Active ingredients for formulations are obtained from homologous series of carboxylic acids, alcohols, ketones, and lactones which span a similar range of volatility and which occur naturally on the skin surface. Volatile silicone fluid imparts mildness and water repellency to the repellent formulations. The new natural repellent exhibits the longevity and repellency that is comparable to N,N-diethyl-m-toluamide (DEET), a synthetic compound employed in almost all commercial formulations, but the inventive natural repellent is more acceptable than DEET, which has an unpleasant odor and imparts a greasy feel to the skin. The inventive insect repellent, formulated in a volatile silicone fluid, was shown to repel and incapacitate stable flies. This finding demonstrated that repellency was not limited to mosquitoes, but extends to other biting flies or insects, thus demonstrating the utility of the novel insect repellent for protecting pets and livestock as well as humans.

The invention relates to a producing technology of a biologic ferment complete feed, which adopts the following weight shares: mixed bacteria 0.2 to 0.5 share, mushroom bacteria dregs 35 to 45 shares, bean pulp 20 to 30 shares, raw oyster 1 to 3 shares, and wheat bran 10 to 25 shares; the mushroom bacteria dregs, the bean pulp, the raw oyster and the wheat bran are mixed and smashed and sieved through a 20 to 30 mesh sieve; the mixed bacteria is mixed into the shares and blended evenly; all mixed materials are positioned into a ferment pool to be sealed and fermented; the ferment temperature is 35 plus or minus 3 DEG C; the feed is made after fermenting 130 to 145 hours. The biologic ferment complete feed produced by the invention technology can effectively improve the animal digestive system function, strengthen the food absorbing volume of the animal, restrict the disease causing bacteria in the animal body, adjust the beneficial bacteria balance in the animal body, lead the animal nutrition to reach the green nuisance free standard, and improve the appearance condition of the animal, thus overcoming the problem that the weight increasing of the domestic animal caused by the over high coarse fiber content in the bacteria bran is influenced.

The invention provides effective technology for extracting active ingredients of Entermorpha and a method for preparing an Entermorpha alga fertilizer. The method is characterized by comprising: taking the Entermorpha as a raw material, effectively extracting the active ingredients of the Entermorpha through technical processes such as pretreatment of raw materials, leaching, neutralization, concentration and combination, taking an extracting solution as a base fluid, combining the extracting solution with at least one composition of humic acid, urea, potassium dihydrogen phosphate, potassiumsulfate, monoammonium phosphate and microelement, and preparing the high-activity Entermorpha alga fertilizer. The Entermorpha alga fertilizer is rich in active substances of algae, not only can strengthen photosynthesis of crops, increase the yield of the crops and improve the product quality but also can strengthen the cold resistance, the drought resistance, the stress resistance and the disease resistance of the crops, promote earliness of the crops and increase the fertile flower percentage and the fertile fruit percentage, has lower production cost, good solubility and safe use, is friendly and harmless to human beings, domestic animals and the natural environment, and is a novel environment-friendly fertilizer suitable for modern agriculture.

The invention discloses a slowly-released compound acidifier for poultry and livestock feed, a preparation method thereof and feed containing the same. The compound acidifier comprises the following compositions in part by weight: 30 to 80 parts of complex organic acid, 15 to 50 parts of supplementary materials and 5 to 20 parts of coating agents. The complex organic acid is citric acid, fumaric acid, malic acid, lactic acid, linoleic acid, crataegolic acid, ursolic acid, chlorogenic acid, glycyrrhizic acid and oleanolic acid, and the supplementary materials are silicon dioxide, hydroxypropyl methylcellulose and ethyl cellulose. The acidifier is scientifically proportioned, has strong efficiency and is long-acting and slow-releasing, nutrients in the feed are free from being damaged, the acidifier has good fluidity and is easy to be uniformly mixed with the feed, the digestive absorption of nutrients can be promoted, the conversion rate of the feed can be improved, the productivity of poultry and livestock can be improved, the time for domestic animals for sale can be effectively shortened, the health of gastrointestinal mucosa of the animals can be protected, the immunologic function of the animals can be strengthened, and diseases can be prevented.

A protective coat for domestic animals, such as dogs, is reversible to alternatively protect against heat or cold. The coat is made of a light-weight flexible material that is preferably fastened with the use of hook-and-loop fastening strips. The coat is a two-ply garment, one ply providing a water-repellent surface, while the second ply provides a heat radiation-reflective surface. The preferred material used in constructing the pet garment is Astrolon TM . The coat is a lamination of two sheets providing the desired protective qualities. The first sheet is aluminized clear polyethylene, and the second sheet is a colored polyethylene. The two sheets are heat-fused together. A cloth piping is sewn around the side edges of the lamination.

Substituted biaryl piperazinyl-pyridine analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

The present invention is directed toward animal feeding devices, and more particularly, to an elevated feeding apparatus for domestic animals such as dogs and cats. The device is constructed and arranged to be used for pet feeding with or without riser legs and provides space saving features for shipping and storage. As a space saving feature, the dish retainer is provided with a first fastener system positioned under the dish retainer so that riser legs can be stored in a nested state with respect to each other and within the confines of the perimeter wall. A second fastener system is provided near the distal ends of the dish retainer for attachment of the riser legs to elevate the dish retainer when desired.

The invention discloses a green biological active feed, which relates to the technical field of feeds. The green biological active feed is prepared from the following materials in part by weight: 40 to 80 parts of straw, 5 to 30 parts of corn four, 5 to 25 parts of cake dregs, 5 to 25 parts of wheat bran, 0.1 to 0.2 part of complex bacteria and 0.1 to 0.2 part of complex enzyme. During preparation, the straw is crushed and then is uniformly mixed with the corn flour, the cake dregs and the wheat bran; the complex bacteria and the complex enzyme are mixed into the mixture; water is added into the mixture to ensure that the water content reaches 45 to 50 percent, and the mixture is filled in a big tank, sealed and stored for later use; or the mixture is baked or dried by natural wind for storage and later use. The green biological active feed has the following advantages of: (1) improving the balance of intestinal flora, and improving the feed utilization rate; (2) promoting the growth of meat livestock and poultry, and shortening the breeding cycle; (3) strengthening the body conditions of laying hens, ducks and geese, and having a significant strengthening action on prolonging theegg-laying peak period; (4) strengthening the body condition of female domestic animals, and improving the yielding rate; (5) strengthening the body conditions of the livestock and poultry, enhancingthe disease prevention and disease resisting capacities, and reducing the sickness rate; and (6) purifying the culture environment, and improving the meat quality due to no public nuisances and no residues.

Compounds of Formula (1) are provided, as are methods for their preparation. The variables Z₁, Z₂, Z₃, R₄, R₅, R₆, R₇, R₈, and Ar in the above Formula are defined herein. Such compounds may be used to modulate ligand binding to GABA_A receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals, and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting GABA_A receptors (e.g., receptor localization studies).

Substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

The present invention for a puppy apartment for use by domestic animals includes a container portion and a room divider having a kennel opening thereby allowing the animal to pass between apartment bedroom and bathroom portions. Adjustable apartment boundary regions for bathroom, bedroom, and living areas are adaptably configured to accommodate the pet in a comfortable domestic training environment. The present invention includes a method for providing positive and consistent household pet puppy training with the puppy apartment device.

The present invention proposes formative agent of protein complex, in which a polyphenol is useful component, and the agent is useful as gene complex, cell adhesion inhibitor or immune tolerogen. The polyphenol of forming the agent is selected from catechin group consisting of epigallocatechin-gallate, tannic acids, or proanto-dianisidine, a protein of the protein complex is selected from proteins consisting of animal proteins composed of polypeptide chain of peptide-combined amino acids, vegetative proteins, nucleus proteins, glycogen proteins, lipo-proteins and metal proteins, the gene complex comprises by compositing genes by polyphenol catechins in order to introduce genes to cells of animals or human bodies, a cell composed of the cell adhesion inhibitor is selected from cells consisting of an animal cell including a stem cell, skin cell, mucosa cell, hepatocyte, islet cell, neural cell, cartilage cell, endothelial cell, epidermal cell, osteocyte or muscle cell isolated from human or animal organism, or sperm, ovum or fertilized egg of domestic animals or fishes and a tissue or an organ for transplantation of the immune tolerogen is selected from the tissue or the organ consisting of skin, blood vessel, cornea, kidney, heart, liver, umbilical cord, bowels, nerve, lung, placenta or pancreas.

Compounds of Formula I are provided.

In which the variables are as described herein. Such compounds may be used to modulate CB1 activity in vivo or in vitro, and are particularly useful in the treatment of conditions responsive to CB1 modulation in humans, domesticated companion animals and livestock animals, including appetite disorders, obesity and addictive disorders. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies and various in vitro assays.

Multiple strains and species of Campylobacter were found to share a common glycan moitie which is present in a plurality of surface-exposed glycoproteins. This glycan has the formula: GalNAc-a1,4-GalNAc-a1,4-[Glc-β1,3]GalNAc-a1,4-GalNAc-a1,4-GalNAc-a1,3-Bac, wherein Bac is 2,4-diacetamido-2,4,6-trideoxy-D-glucopyranose. This glycan and immunologically active fragments of it have use as vaccines against campylobacter infection in humans and animals. As well, antibodies which specifically bind these compounds may be provided. Such antibodies and vaccines may be used to prevent or neutralize campylobacter infections in livestock thereby preventing this pathogen from entering the human food chain. The glycan may be linked to one or more amino acids to form a glycopeptide. As well, a method for determining the glycan structure of an intact glycoprotein consists of subjecting a sample to high resolution magic angle spinning nuclear magnetic resonance (HR-MAS-NMR) spectroscopy.

A therapeutic gel pad for household pets and farm animals is worn on a pet's injured or sensitive body part to facilitate healing and provide protection or treatment. The therapeutic gel pad includes a base gel layer and an upper gel layer appointed to intimately contact a body region of the household animal and/or farm animal. The therapeutic gel pad may comprise a massaging gel sole or may comprise a gel inner layer or gel pad and may be provided with a securing member for securing the pad to the animal's body. Advantageously, the therapeutic gel pad may directly deliver medicament to the injury. It may also provide cold treatment or hot treatment therapies, while providing cushioning, shock absorption and protection from dirt and debris.

The application discloses a multi-chamber, multi-formulation fluid delivery system, comprising a multi-chamber applicator in fluid communication with multi-chamber packaging. Applicators according to the instant disclosure have reduced squeeze-strength requirements, and are useful for dispensing fluids, including medicaments, to animals, including livestock animals. The multi-chamber packaging provides separate storage for formulations containing incompatible active ingredients, and is suitable for use with the multi-chamber applicator. The application also discloses methods for using the system to simultaneously deliver multiple active ingredients, at least some of which are not suitable for co-formulation, thus reducing the time, economic burden and animal stress involved with applying multiple, separate formulations to animals.