160 results about "Viral pneumonia" patented technology

The invention provides a deep learning algorithm-based classification method of bacterial pneumonia and viral pneumonia in children. According to the method, a source data set is manually labeled; onthe basis of the combination of a full convolutional network semantic segmentation algorithm and a convolutional neural network algorithm, the full convolutional network semantic segmentation algorithm is adopted to perform lung region foreground segmentation on an image so as to obtain a region of interest, the extracted region of interest is inputted to a convolutional neural network model so asto train a classifier, and therefore, the category of an unknown chest X-ray image can be predicted, and the high-dimensional features of the region of interest are extracted; and a traditional imageprocessing method is adopted to extract the low-dimensional features of the region of interest; and the high-dimensional features and the low-dimensional features are used to train a non-linear classifier; and the category of the unknown X-ray image is predicted, and the type of the pneumonia of a patient can be judged. Since a main component analysis algorithm is used to perform dimensionality reduction on the features, and therefore, the amount of calculation can be reduced; and the features which have been subjected to mixed dimensionality reduction are inputted into the nonlinear classifier, and the category of the unknown X-ray image can be predicted.

A Chinese medicine "Qingfei oral liquid" for treating baby's viral pneumonitis is prepared from 10 Chinese-medicinal materials including ephedra, gypsum, bitter apricot kernel, red sage etc through grinding and distilling bitter apricot kernel to obtain liquid, decocting its dregs along with others twice, concentrating, depositing in alcohol, taking supernatant, recovering alcohol, adding water, boiling, filtering, mixing with cane sugar solution and said distilled liquid, adding water, and sterilizing. Its advantage is higher curative effect.

The invention relates to the technical field of the breeding of live hogs, and particularly relates to antiviral live-hog feed, which is prepared from 90 percent of basal feed, 6 percent of Chinese herbal medicinal additive and 4 percent of growth promoter, wherein the basal feed is prepared from corn, peanut meal, bean meal, rice bran and wheat bran; the Chinese herbal medicinal additive is prepared from herba houttuyniae, pericarpium citri reticulatae, herba taraxaci, radix bupleuri, fructus forsythiae, radix astragali seu hedysari, flos lonicerae, caulis lonicerae japonicae, radix isatidis and the like; the growth promoter is prepared from shrimp shell powder, bone powder, fish meal, folic acid, choline, calcium lactate and the like. The antiviral live-hog feed is complete and balanced in nutrition; the immunity of a hog can be enhanced; the infection rate of a virus is reduced; the use of an antibiotic and the residue of a medicine are reduced. Through the compatibility of multiple traditional Chinese medicinal materials, the antiviral live-hog feed has the effects of clearing away heat and toxic materials and being obviously antiviral, has obvious inhibiting effects on all of epidemic diarrhea, a porcine reproductive and respiratory syndrome, influenza viral pneumonia and the like, and can be used for replacing a conventional antibiotic; the residue of the medicine is reduced; the economic benefit of a breeder is improved.

The invention discloses an application of a compound to preparation of medicines for treating viral pneumonia, and relates to the technical field of drugs. The technical problem that novel antiviral drugs are deficient in the prior art, can be solved. The compound comprises a purine compound adopting the structure as shown in the formula 1, and / or an anthraquinone derivative adopting the structureas shown in the formula 2. The purine compound adopting the structure as shown in the formula 1, and / or the anthraquinone derivative adopting the structure as shown in the formula 2 both can show predominant effect for resisting viral pneumonia when being separately used or used jointly. Drugs for treating viral pneumonia, are prepared by the compound provided by the invention are more notable inactivity compared with clinical frontline drugs, and are better than drugs of ribavirin, oseltamivir and the like.

A Chinese medicine for treating upper respiratory tract infection, bronchitis, viral pneumonia, pyrogenic diseas, gynopathic inflammation, etc is prepared from houttuynia and honeysuckle flower through distilling extraction, extracting by water or alcohol, and mixing both extracts together. Its advantage is high curative effect.

The invention discloses compounds having virus resistance and a composition thereof. The composition comprises one or more of the 13 compounds comprising 6'-O-caffeoyl deacetyl asperulosidic acid methyl ester. The compounds having virus resistance and the composition thereof can be extracted from plants and can also be prepared by synthesis. The composition comprising the compounds having virus resistance can prevent and treat viral infection-caused diseases such as influenza, myocarditis, conjunctivitis, viral pneumonia, encephalitis, leukemia, hepatitis B, hepatitis C, AIDS, genitourinary system infection, EB virus infection, human papillomavirus infection and cytomegalovirus infection. The composition can be prepared into an oral preparation, an injection, a spray, a subcutaneous injection and an anus suppository.

The invention relates to an in-situ gel preparation of potassium dehydroandrographolide succinate and a preparation method thereof. The preparation is prepared from potassium dehydroandrographolide succinate (dehydration andrographolide butanedioic acid ester single sylvite half), in-site gel substrates recognized in the field, and other pharmaceutic adjuvants necessary for other pharmacy by using water as a solvent. In-situ gel of potassium dehydroandrographolide succinate is liquid freely moving outside a body, and forms semisolid gel after patients take the gel. The invention has the advantages of definite effect, stable performance, simple preparation, convenient administration, strong compliance for patients, no toxic and side effect, no untoward effect, high bioavailability, and on the like. The in-situ gel preparation has good antipyretic and antiinflammatory action, can be used for clinically treating viral respiratory tract infection and viral pneumonia, can be used as alternative medicine for potassium dehydroandrographolide succinate injection, and is particularly suitable for infants and patients who have trouble in taking medicine.

The invention discloses an extract of Rheum lhasaense A.J.Li etP.K.Hsiao and application of the extract of Rheum lhasaense A.J.Li etP.K.Hsiaoin in preparation of a medicine for preventing and / or treating viral pneumonia. The effective ingredients of the extract of Rheum lhasaense A.J.Li etP.K.Hsiao are toluylene substances which mainly are piceatannol3'-O-glucoside, polydatin, methyl polydatin, piceatannol and resveratrol. The extract has various pharmacological activities such as antiviral, antibacterial, anti-inflammatory, and scavenging free radicals, can significantly reduce the lung indexof coronavirus-infected mice, is anti-shock, and can be used to prepare pharmaceutical preparations for preventing and treating viral pneumonia.

The invention belongs to the field of preparations of biotechnology medicines, and relates to an interferon lambda-containing aerosol inhalant. The aerosol inhalant contains 1-1000 micrograms of interferon lambda and a right amount of pharmaceutical adjuvant of the aerosol inhalant in a single dosage of administration; preferentially, the aerosol inhalant contains 5-100 micrograms of interferon lambda and a right amount of pharmaceutical adjuvant of the aerosol inhalant in a single dosage of administration; more preferentially, the aerosol inhalant contains 10-50 micrograms of interferon lambda and a right amount of pharmaceutical adjuvant of the aerosol inhalant in a single dosage of administration. Compared with the traditional interferon alpha-containing aerosol inhalant, the interferon lambda-containing aerosol inhalant obviously improves the treatment effect when being used for treating viral pneumonia.

The invention belongs to the field of a biotechnology medicine preparation, and relates to an interferon aerosol propellant. The single-time administration dosage of the interferon aerosol contains 1 to 100 [mu]g of interferon and a proper number of aerosol propellant pharmaceutically acceptable auxiliary materials; and the interferon consists of interferon Alpha and interferon Lambda with the weight ratio being (1:19) to (19:1). Compared with the aerosol propellant singly using the interferon Alpha and the aerosol propellant singly using the interferon Lambda, the interferon aerosol propellant provided by the invention obviously improves the curative effect when being used for treating viral pneumonia.

The invention provides a traditional Chinese medicine composition and application thereof in prevention and treatment of viral pneumonia. According to the traditional Chinese medicine composition, 40-130 parts of fructus forsythiae, edible tulip, honeysuckle, scutellaria baicalensis and folium isatidis are used as basic components, and 50-110 parts of a qi-tonifying yin-nourishing component, 20-50parts of a spleen-tonifying circulation-assisting component, 15-50 parts of a phlegm-heat-clearing component, 14-50 parts of a phlegm-eliminating masses-resolving component and 20-50 parts of a lung-promoting, lung-moistening, lung-astringing and asthma-preventing component which accord with incompatibility of traditional Chinese medicines are matched. The traditional Chinese medicine compositionhas the effects of clearing away heat and toxic materials, dispelling wind and promoting exterior syndrome, relieving cough and reducing sputum and tonifying qi and yin, is suitable for treating thenovel coronavirus pneumonia, can effectively relieve symptoms of patients with the novel coronavirus pneumonia and improve prognosis, reduces the diseaseseverity-causing rate and the case fatality rate, and is clear and remarkable in curative effect.

The invention discloses application of paederoside acid shown as a formula 1 or a plant extract containing the same in medicaments in preparing anti-influenza A virus. The compound and the plant extract containing the same have the obvious anti-influenza A virus activity, and have obvious effects of treating influenza A or influenza A viral pneumonia.

The present invention relates to inhibitors of C5a for use in the treatment of pneumonia, especially viral pneumonia. The invention also relates to the use of inhibitors of C5a in the preparation of a pharmaceutical composition for the treatment of pneumonia, especially viral pneumonia. The inventors further relates to methods for the treatment of pneumonia, especially viral pneumonia, comprising the step of administering a therapeutic amount of an inhibitor of C5a to a subject in need thereof.

The invention discloses an algorithm improvement of biomimetic pattern recognition in imaging pneumonia discrimination. A healthy X-ray film, a viral pneumonia X-ray film and a bacterial pneumonia X-ray film are normalized into experimental images with the same size; the experimental image I after the normalization of the healthy X-ray film image is input into a convolutional neural network to extract an image feature vector; wherein the convolutional neural network comprises a convolutional layer, a pooling layer and a full connection layer. The image feature vector extraction method comprises the steps of A, carrying out convolution on an experimental image I and a convolution kernel, and outputting a result through an activation function to form a feature map 01 of the convolutional layer; carrying out convolution on the feature map 01 and a next convolution kernel, and outputting a result through an activation function to form a feature map 02 of a convolution layer; and the feature map 02 enters a pooling layer as an input image.

The invention relates to a traditional Chinese medicine composite for treating the respiratory disease of livestock and poultry. The composite mainly consists of climbing groundsel herb, cordate houttuynia, honeysuckle and liquorice. The climbing groundsel herb has the functions of clearing heat and detoxicating, improving eyesight, and relieving tickle; the cordate houttuynia has the functions of clearing heat and detoxicating, removing pus and carbuncle, and diuresis and treating stranguria; the honeysuckle has the functions of clearing heat and detoxicating, and cooling and relieving wind heat; and the liquorice has the functions of tonifying spleen and qi, clearing heat and detoxicating, eliminating phlegm and stopping cough, alleviating pain, and moderating the property of herbs. The herbs have the functions of clearing heat and detoxicating, removing carbuncle and pus and the like by cooperatively using. The traditional Chinese medicine composite is used for the treatment of respiratory diseases, bronchial pneumonia, viral pneumonia, purulent diseases and fevered diseases caused by the inner exuberance of heat toxin. The traditional Chinese medicine composite can be prepared into powder, granular formulation, oral solution formulation, injection and the like as required, is fast in response, is free of residual, offers a feasible way for the industrialized production and the large-scale production simultaneously, and is suitable for popularization and application.

The invention relates to an application of oil orange to pharmacy, in particular to an application of oil orange to preparation of an anti-H1N1 flu medicament. The anti-H1N1 flu medicament is a clinically-acceptable preparation prepared by mixing an oil orange flavone extract with the conventional dosage of medically-acceptable auxiliary materials. The medicament has a remarkable inhibiting action on an H1N1 flu virus CPE (Cytopathic Effect), and can be used for remarkably lowering the lung index of an infected person clinically and relieving the viral pneumonia symptom of the infected person.

The invention belongs to the technical field of traditional Chinese medicines, and relates to a dampness-clearing lung-ventilating traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by mass: 5 to 10 parts of raw ephedra herb, 25 to 30 parts of gypsum, 5 to 12 parts of semen armeniacae amarae, 10 to 16 parts of rhizomaanemarrhenae, 10 to 16 parts of radix bupleuri chinensis, 10 to 16 parts of rhizoma seu radix notopterygii, 10-16 parts of rhizoma atractylodis, 10-16 parts of wrinkled gianthyssop herb and 5-12 partsof medicated leaven. The invention further provides application of the dampness-clearing lung-ventilating traditional Chinese medicine composition in preparation of a medicine for treating community-acquired pneumonia, especially viral pneumonia or suspected COVID-19. The dampness-clearing lung-ventilating traditional Chinese medicine composition of the invention can be used as a medicine for treating suspected cases of COVID-19 to cut off and reverse an illness state in an early stage and prevent deterioration and development of the illness state.

The invention discloses application of Anerning granules in preparing a medicament for treating viral pneumonia. The granules have a remarkable curative effect on viral pneumonia caused by respiratory syncytial virus and influenza virus, can be used for remarkably reducing the lung index, and is in dose-effect relationship. The Anerning granules can be used for protecting experimental animal death caused by respiratory syncytial virus (RSV), and has a remarkable inhibition effect on spleen index and thymus index reduction caused by RSV, can be used for reducing animal death cased by viral pneumonia, and can be used for remarkably protecting the immunity of experimental animals.

The invention discloses application of a bupleurum chinense extract in treatment of viral pneumonia, and relates to the technical field of traditional Chinese medicines. The invention discloses application of the bupleurum chinense extract in preparation of a medicine for treating viral pneumonia. The bupleurum tenuifolium extract has a relatively strong inhibition effect on viruses, has a lower usage amount, can be used for treating pneumonia caused by influenza A viruses, human rhinoviruses, human adenoviruses, common coronaviruses, coxsackie viruses or parainfluenza viruses, and is ineffective to viral pneumonia caused by herpes simplex viruses and human metapneumoviruses. A new strategy is provided for treating viral pneumonia.

The invention discloses bag tea with effects of improving immunity and preventing viruses. The bag tea is made of the following raw material medicines: 1.5-6 parts of herb of winkled gianthyssop, 2.5-10 parts of honeysuckle flowers, 1.5-6 parts of dried tangerine peel, 1-4 parts of common reed rhizome , 1-4 parts of mulberry leaves and 1.5-6 parts of ginseng. According to the bag tea, traditionalChinese medicine materials are screened according to the idea of syndrome differentiation and treatment, the traditional Chinese medicine bag tea disclosed by the invention is scientific and reasonable in proportioning, and experiment results show that the traditional Chinese medicine bag tea disclosed by the invention has functions of clearing heat and removing toxins, diaphoresis relieving superficies and drying dampness, preventing viruses and improving immunity, and is capable of improving the capability of preventing influenza viruses and novel coronaviruses (SARS-CoV-2 for short). In addition, the bag tea has effects of clearing heat and moisturizing the lung, and the like, has a good assistant treatment function on viral pneumonia and the like, is natural in medicine taste, is safe,is free of adverse reaction in long-term taking, and is applicable to both the old and the young.

The invention relates to a traditional Chinese medicine composition suitable for viral cold and viral pneumonia as well as an administration mode and preparation of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight. 5-15 parts of ginseng, 5-15 parts of astragalus membranaceus, 5-15 parts of notopterygium root, 5-15 parts of radix angelicae pubescentis, 5-15 parts of ligusticum wallichii, 5-15 parts of radix bupleuri, 5-15 parts of platycodon grandiflorum, 5-15 parts of fructus aurantii, 5-15 parts of radix peucedani, 5-15 parts of poria cocos, 5-15 parts of honeysuckle, 5-15 parts of fructus forsythiae, 5-15 parts of rhizoma atractylodis, 2-10 parts of liquorice, 1-5 parts of mint and 1-9 parts of rhizoma zingiberis.

The invention discloses a traditional Chinese medicine preparation for treating viral pneumonia and a preparation method and application thereof. The traditional Chinese medicine preparation is prepared from 1-2 parts of Semen Oroxyli, 4-6 parts of gardenia and 3-6 parts of Sophora flavescens. The preparation method is performed through water extraction, alcohol precipitation and countercurrent extraction. The traditional Chinese medicine preparation can be used for treating viral pneumonia, has antipyretic, anti-bacterial and anti-viral functions, and has the treatment effects of clearing heat and detoxifying, eliminating phlegm and stopping cough.

The invention provides a viral pneumonia auxiliary diagnosis device and method. The device comprises a viral pneumonia auxiliary diagnosis system. The viral pneumonia auxiliary diagnosis system is connected with a thermal imaging camera, a security check door, a face recognition system, an inspection information system and a medical image information system, integrates personnel identity information, a human face temperature numerical value, an inspection numerical value and image diagnosis data, calculates various characteristic values, obtains the suspected degree of viral pneumonia and judges whether a patient enters a fever outpatient service or a common outpatient service accurately through the suspected degree of viral pneumonia. According to the invention, full-process management ofviral pneumonia is realized, and missing detection and work negligence are reduced.

The invention belongs to the field of medicinal compositions for resisting virus, and relates to an aerosol inhalant containing interferon alpha and terbutaline sulfate. The aerosol inhalant contains a therapeutically effective amount of interferon alpha, a therapeutically effective amount of terbutaline sulfate and an appropriate amount of pharmaceutic auxiliary materials; preferably, single dose of the aerosol inhalant contains 2.5 to 30 mu g of interferon alpha, 0.5 to 2 mg of terbutaline sulfate, and an appropriate amount of pharmaceutic auxiliary materials; and more preferably, single dose of the aerosol inhalant contains 10 to 20 mu g of interferon alpha, 1 to 1.5mg of terbutaline sulfate and an appropriate amount of pharmaceutic auxiliary materials. Compared with the interferon alpha or the terbutaline sulfate, the aerosol inhalant containing the interferon alpha and the terbutaline sulfate has the advantages that the effect of treating viral pneumonia can be improved obviously.

The invention discloses a pharmaceutical composition containing andrographolide and a use of the pharmaceutical composition, and relates to a drug containing common andrographis herb, belonging to the technical field of medicines. The pharmaceutical composition containing andrographolide comprises the following components in parts by mass: 95-100 parts of andrographolide, 0-5 parts of andrographolide derivatives and the balance of pharmaceutically acceptable carriers. The pharmaceutical composition containing andrographolide disclosed by the invention has the effects of resisting bacteria, diminishing inflammation, resisting viruses, bringing down a fever, regulating the immunity and resisting tumors, can be used for restraining synthesis, release and inflammatory activity of the prostaglandin, and is mainly used for treating diseases such as bacillary dysentery, viral pneumonia, viral upper respiratory tract infection and acute tonsillitis.

The invention provides application of rheidin in preparing drugs for treating viral diseases. It is proved through experiments that rheidin has the inhibiting effects on cell lesions induced by an influenza virus, a respiratory syncytial virus, a herpes virus and enterovirus EV71 type, and the survival rate of virus infected cells can be increased; meanwhile, virus replication can be inhibited in a body, the survival rate of virus infected animals is increased, the survival time of the virus infected animals is prolonged, symptoms of diseases caused by virus infection are relieved, and therefore the effects of treating influenza, viral pneumonia, upper respiratory tract infection, skin herpes simplex viruses and hand-foot-mouth diseases and an application value are achieved.

The invention provides a medicine used for treating influenza, upper respiratory infection and viral pneumonia. The medicine is glycoprotein or a mixture of polysaccharide and protein or polypeptide or protein. The glycoprotein provided by the invention has a stabilization effect on body temperatures of endotoxin pyrogenic domestic rabbits, and has an obvious antipyretic effect; the medicine provided by the invention is used for treating the influenza, the upper respiratory infection and the viral pneumonia, and no symptoms of bronchitis, pneumonia and tuberculosis; the complication is 0; the toxin-free concentration of the medicine to Vero-E6 cells is 100 mu g / ml, and has an obvious inhibition effect on SARS viruses. The medicine provided by the invention has obvious pharmacologic actions on seven aspects of in-vitro virus resistance, in-vivo virus resistance, bacterium inhibition, inflammation resistance, antipyretic action, pain alleviation and immunologic function improvement; the medicine has the characteristics of safety, high efficiency and no side effect and has functions of preventing and treating respiratory system diseases, and broad-spectrum anti-virus, anti-inflammatory, anticoagulation, bacteria resisting, antipyretic and immunity adjusting functions.

The invention discloses a traditional Chinese medicine composition for treating cold, as well as a preparation method and an application thereof. The traditional Chinese medicine composition for treating cold is prepared by mainly adopting active pharmaceutical ingredients such as folium perillae, radix scutellariae, fructus arctii and the like. The traditional Chinese medicine composition has the functions of eliminating inflammation and treating viral pneumonia.

The invention relates to a method for preventing and treating viral respiratory diseases by atomizing an iodine-containing disinfectant, which can be widely applied to prevention and treatment of viral pneumonia, viral influenza and cold, and particularly has special significance for preventing and treating respiratory system virus infection. In 2019, a paper published by a German scientist in loimology pointed out: the infectious disease can be resisted by iodophor, an iodophor mouthwash can remarkably reduce the virus load of the oral cavity and oropharynx, and infection of two coronaviruses, namely SARS and MERS can be effectively resisted. Based on the particularity of human lung and respiratory tract structures, the invention is designed according to the thought that the human lung and respiratory tract are regarded as special organs which are relatively open to the outside, and most viruses are sensitive to iodine. Firstly, iodine-containing liquid (preferably iodophor) is atomized, then inhaled through the mouth and the nose, sequentially passes through the throat and the trachea and then enters the lung of the human body, and the purpose of inhibiting or killing viruses inpulmonary alveoli and respiratory tracts is achieved. The method is also suitable for daily virus defense of healthy people.