The invention relates to a production method of semen lepidii and fructus jujubae lung purging granules, in particular to production of semen lepidii and fructus jujubae lung purging granules from twobulk medicine materials of fructus jujubae and semen lepidii through technologies of pretreatment, decoction, decotion with stir-fried semen lepidii wrapped, filtering, concentration, drying, granulation and the like, and belongs to the field of traditional Chinese medicine preparations. The obtained semen lepidii and fructus jujubae lung purging granules have the efficacy of purging the lung, inducing diuresis, descending qi and dissolving phlegm, and are used for treating respiratory system disease of pulmonary heart disease, emphysema, wet pleurisy, lobar pneumonia, bronchial asthma, chronic bronchitis, pertussis and the like, the recipe is simple, however, the semen lepidii and fructus jujubae lung purging granules have significantly-curative and excellent effects. According to production of the semen lepidii and fructus jujubae lung purging granules from the two bulk medicine materials of the fructus jujubae and the semen lepidii through the technologies of pretreatment, decoction, decotion with the stir-fried semen lepidii wrapped, filtering, concentration, drying, granulation and the like, by conducting dosage form reform and innovation on traditional Chinese medicine decotion, the problems that production, taking and carrying are inconvenient, and the like can be effectively solved, the production method of the semen lepidii and fructus jujubae lung purging granules isscientific and reasonable, the materials for efficacy are kept furthest, and large-scale production is easy, so that the production method of the semen lepidii and fructus jujubae lung purging granules has significant economic benefits and application prospects.