The invention provides a pH
response type porous modified Japanese banana core
fiber multifunctional composite medical dressing and a preparation method thereof.The dressing takes Japanese banana core fibers with low
crystallinity and high hydroxyl
exposure degree as a base material, a
porous network is formed through carboxymethylation modification,
chitosan,
baicalin and
clindamycin are loaded, and the pH
response type porous modified Japanese banana core
fiber multifunctional composite medical dressing is obtained. The preparation method comprises the following steps: pretreating
musa basjoo core fibers with an H2O2 solution containing disodium
ethylene diamine tetraacetate to obtain short fibers, proportionally mixing the short fibers,
chitosan and
baicalin, adding the obtained mixture into a
dissolution system, carrying out
electrospinning to obtain a
nanofiber membrane, carrying out
freeze drying to construct a porous structure, and carrying out carboxymethylation modification and pH-responsive
drug loading to obtain the antibacterial hydrogel. And finally, compounding collagen, rolling and sterilizing. The pH
response type porous modified banana core
fiber multifunctional composite medical dressing has the functions of pH sensitive
drug release, efficient
antibiosis, rapid
hemostasis, wound repair promotion and the like, and high-valued utilization of waste banana core fibers is achieved.