The invention discloses
nucleus eliminating granules which are prepared by the following steps: adding water into 12 medicinal materials, namely selfheal,
oyster,
kelp, beautiful sweetgum fruit, fructus aurantii, cowherb seed,
salvia miltiorrhiza,
curcuma zedoary,
ligusticum wallichii, white paeony root,
corydalis tuber and
radix bupleuri, heating, extracting, filtering, concentrating and
drying to obtain medicinal
powder; and sieving, adding auxiliary materials, adding a
wetting agent, preparing a soft material, granulating, and
drying to obtain the kernel eliminating granules. The invention further discloses a preparation method of the
nucleus eliminating particles, a thin-layer
chromatography identification and
content determination method and application of the
nucleus eliminating particles. According to the invention, the nucleus-eliminating mixture is developed into the nucleus-eliminating particles, the forming rate, the
dissolution rate, the
moisture absorption rate, the fluidity and the like of the nucleus-eliminating particles all meet the requirements of
Chinese Pharmacopoeia, and the stability experiment result shows that the product stability is good; the
curative effect of the nucleus eliminating granules on breast pain,
breast nodules,
hyperplasia of mammary glands and breast diseases can be achieved; doctors realize accurate medication under treatment based on
syndrome differentiation, and the flexibility of adjusting prescriptions along with symptoms is guaranteed; on the other hand, more convenient carrying and taking experience can be provided for the patient.