76 results about "Fibroma" patented technology

The invention is a transvaginal ultrasound probe having an attached echogenic needle that is useful in the treatment of uterine fibroids. The echogenic needle has an echogenic surface near its tip that allows the physician to visualize its location using ultrasound imaging. In one embodiment, the needle has an active electrode at its distal end. The active electrode supplies radio frequency energy to a fibroids causing necrosis of the targeted fibroid or by destroying the fibroid's vascular supply. The radio frequency needle preferably has a safety device that shuts-off energy if the needle punctures the uterine wall. In a second embodiment, the needle has a cryogen supply tube and cryogen supply. This embodiment destroys fibroid tissue by freezing it or its vascular supply when the tissue comes in contact with the needle's frozen distal end. The invention further includes the method of using the ultrasound probe with the attached needle.

The invention is a transvaginal ultrasound probe having an attached echogenic needle that is useful in the treatment of uterine fibroids. The echogenic needle has an echogenic surface near its tip that allows the physician to visualize its location using ultrasound imaging. In one embodiment, the needle has an active electrode at its distal end. The active electrode supplies radio frequency energy to a fibroids causing necrosis of the targeted fibroid or by destroying the fibroid's vascular supply. The radio frequency needle preferably has a safety device that shuts-off energy if the needle punctures the uterine wall. In a second embodiment, the needle has a cryogen supply tube and cryogen supply. This embodiment destroys fibroid tissue by freezing it or its vascular supply when the tissue comes in contact with the needle's frozen distal end. The invention further includes the method of using the ultrasound probe with the attached needle.

Disclosed are: a substance transfer carrier to an extracellular matrix-producing cell in the lung, which comprises a retinoid; a therapeutic agent for fibroid lung, which utilized the carrier; and a preparation kit of the therapeutic agent.

A system for ligating a uterine artery in a patient generally includes a suture transfer tool, suture transfer darts, and one or more sutures. Others systems and implants are described herein for treating and / or eliminating fibroids or fibrous masses in males and females.

Compositions comprising collagenase G and collagenase H (in a ratio between 1:2.5 and 1:3.5), optionally formulated in hydrogels, and its uses as medicament for the treatment of diseases involving alterations of collagen, such as fibromatosis, palmar Dupuytren's contracture, La Peyronie's disease, Ledderhose's disease or retractable scars.

The present invention generally relates to improved medical devices, systems, and methods. In many embodiments, devices, systems, and methods for amputating a limb of a patient are provided. In many embodiments, devices, systems, and methods may provide chronic denervation of one or more nerves of a patient as part of a therapeutic treatment. The methods may employ cold for the prevention of neuromas or fibromas associated with amputation of a limb of a patient. Embodiments of the invention include needles that can be advanced through skin or other tissues to cause axonotmesis of a target nerve of the patient and to repeatedly interrupt a regeneration of the nerve so as to provide therapeutic chronic denervation of the target nerve. The therapeutic chronic denervation may delay the formation of neuromas or fibromas in a patient's residual limb and / or may provide long lasting and permanent pain relief associated with the target nerve.

The present invention provides compositions, desirably pharmaceutical compositions, containing micronized tanaproget. The compositions can also contain microcrystalline cellulose, croscarmellose sodium, anhydrous lactose, and magnesium stearate; or can contain microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, povidone, and magnesium stearate. The compositions are useful in contraception and hormone replacement therapy and in the treatment and / or prevention of uterine myometrial fibroids, benign prostatic hypertrophy, benign and malignant neoplastic disease, dysfunctional bleeding, uterine leiomyomata, endometriosis, polycystic ovary syndrome, and carcinomas and adenocarcinomas of the pituitary, endometrium, kidney, ovary, breast, colon, and prostate and other hormone-dependent tumors, and in the preparation of medicaments useful therefore Additional uses include stimulation of food intake.

There is provided a microcatheter with a tapering wall thickness shaft having varying stiffness / flexibility along its length from proximal end near the medical practitioner to the distal end near the target site in the patient, such as with at least three segments. The shaft is prepared of a thermoplastic material having varying composition along its length. The distal end may be shaped according to the required use just prior to the medical procedure. The microcatheter is particularly adapted for the delivery of microspheric compositions for treatment of tumors or fibroids by embolization of peripheral blood vessels of the tumor or fibroid.

Use of a macrolide antibiotic for the manufacture of a medicament for the treatment or prevention of a cancer selected from colorectal cancer, Desmoid tumor, bladder cancer, gastric cancer, and breast cancer, the macrolide antibiotic being one or more of : tylosin, pharmaceutically acceptable salts thereof, and derivatives thereof; erythromycin, pharmaceutically acceptable salts thereof, and derivatives thereof; oleandomycin, pharmaceutically acceptable salts thereof, and derivatives thereof; and spiramycin, pharmaceutically acceptable salts thereof, and derivatives thereof. Also provided are pharmaceutical compositions and methods for the treatment or prevention of the above mentioned cancers and methods for treating or preventing, in a mammal, a cancer that expresses a mutated APC gene.

Tanaproget polymorph Form II, processes for preparing tanaproget polymorph Form II, pharmaceutical compositions including tanaproget polymorph Form II, micronized tanaproget polymorph Form II, and processes for converting Form II to tanaproget Form I are provided. Also provided are methods of contraception, hormone replacement therapy, stimulation of food intake and treating or preventing uterine myometrial fibroids, benign prostatic hypertrophy, benign and malignant neoplastic disease, dysfunctional bleeding, uterine leiomyomata, endometriosis, polycystic ovary syndrome, or carcinomas and adenocarcinomas comprising administering polymorph Form II to a mammalian subject.

The invention discloses powder for strengthening body resistance and eliminating tumor, and a preparation method and application thereof. The powder is prepared from red ginseng, caterpillar fungus, human placenta, scorpion, centipede, trogopterus dung, long-nosed pit viper, antlers sheet, pangolin scales, ground beetle, notoginseng root, dogtooth violet, dragon's blood, amber, myrrh, dried ginger, asafetida, gecko, zedoary, fructus amomi, muskroot-like semiaquilegia root, airpotato yam rhizome, fritillaria, hive, vietnamese sophora root, cicada shell, eleutherococcus senticosus, raw largehead atractylodes rhizome, solanum nigrum and hairyvein agrimonia herb and bud. The powder is convenient to prepare, can be used for treating various cyst, fibroma, myoma, malignant and the like effectively, and has a good therapeutic effect and an auxiliary effect for treating diseases such as abdominal distention, poor appetite, weakness and pain caused by various malignant tumors.

Tanaproget polymorph Form II, processes for preparing tanaproget polymorph Form II, pharmaceutical compositions including tanaproget polymorph Form II, micronized tanaproget polymorph Form II, and processes for converting Form II to tanaproget Form I are provided. Also provided are methods of contraception, hormone replacement therapy, stimulation of food intake and treating or preventing uterine myometrial fibroids, benign prostatic hypertrophy, benign and malignant neoplastic disease, dysfunctional bleeding, uterine leiomyomata, endometriosis, polycystic ovary syndrome, or carcinomas and adenocarcinomas comprising administering polymorph Form II to a mammalian subject.

Minimally invasive surgical instruments and procedures for treating fibroids within avascular space, particularly uterine fibroids, by interrupting the blood supply to the fibroid, are disclosed. One embodiment of a dissection instrument for detaching the fibroid comprises fluid delivery into the avascular space to expand the space and detach the fibroid mass from blood vessels traversing the avascular space through hydro-dissection. The dissection instrument may comprise an inflatable balloon that is shaped to be inflated in the avascular space to expand and dissect the space, at least partially surrounding the fibroid mass, and detach the blood vessels traversing the avascular space. The dissection instrument may comprises a fibroid mass penetrating and gripping tip that enables twisting or rotation of the fibroid mass sufficiently to detach the blood vessels. The detached fibroid mass may be left in place or removed.

The invention relates to a medicine, in particular to a traditional Chinese medicine preparation for treating mastosis, and provides a comprehensive traditional Chinese medicine mastosis preparation. The comprehensive traditional Chinese medicine mastosis preparation can treat various types of mastosis such as breast cystic hyperplasia, breast fibroma and mastitis with the following types, namely liver-Qi depression, phlegm-static coagulation, damp-heat stagnation, insufficiency of both the spleen and the kidney, and Chong-Ren disharmony. The comprehensive traditional Chinese medicine mastosis preparation is a medicine prepared from the following bulk medicines in portion by weight: 15 portions of Snakegourd Fruit, 15 portions of Astragalus membranaceus, 15 portions of turtle shells, 6 portions of ginseng, 6 portions of pseudo-ginseng, 9 portions of Salvia miltiorrhiza, 9 portions of Chinese angelica, 9 portions of Paeonia lactiflora, 9 portions of Atractylodes macrocephaia, 9 portions of Poria cocos, 6 portions of Chinese thorowax roots, 6 portions of green tangerine orange peels, 6 portions of tangerine seeds, 6 portions of liquorice, 6 portions of aucklandia roots, 6 portions of Fructus Amomi, 6 portions of Nutgrass Galingale Rhizome, 6 portions of rhizoma corydalis, 6 portions of Fritillaria thunbergii, 9 portions of Scrophularia ningpoensis, 6 portions of selfheal, 6 portions of Brassica alba boiss, 9 portions of radix rehmanniae, 6 portions of cistanche deserticola, 9 portions of weeping forsythia, 9 portions of honeysuckle and 9 portions of dandelion. The traditional Chinese medicine preparation for treating mastosis is the traditional Chinese medicine preparation capable of comprehensively treating mastosis, so that people can take the traditional Chinese medicine preparation in daily life as long as the people suffer from mastosis and the condition that the medicine does not suit the illness does not exist.

The present invention generally relates to improved medical devices, systems, and methods. In many embodiments, devices, systems, and methods for amputating a limb of a patient are provided. In many embodiments, devices, systems, and methods may provide chronic denervation of one or more nerves of a patient as part of a therapeutic treatment. The methods may employ cold for the prevention of neuromas or fibromas associated with amputation of a limb of a patient. Embodiments of the invention include needles that can be advanced through skin or other tissues to cause axonotmesis of a target nerve of the patient and to repeatedly interrupt a regeneration of the nerve so as to provide therapeutic chronic denervation of the target nerve. The therapeutic chronic denervation may delay the formation of neuromas or fibromas in a patient's residual limb and / or may provide long lasting and permanent pain relief associated with the target nerve.

The present invention relates to compositions and methods for the treatment of traumatic conditions of the skin including radiation dermatitis, thermal burn, sunburn, dermatomyo-fibromas, and exposure-induced wrinkles, comprising omega-3 fish oils, tocopherols, lavender oil and a suitable amount of a pharmaceutically acceptable carrier, and optionally, one or more of the following: Sodium PCA, or MSM.

The invention discloses a medicine for treating breast diseases. The medicine adopts a Chinese herbal medicine formula and comprises the following drugs by weight: 6 to 10 parts of ground beetle, 9 to 12 parts of processed myrrh, 9 to 12 parts of processed frankincense, 6 to 10 parts of processed Sichuan chinaberry fruit, 10 to 30 parts of bone fossil of big mammals, 10 to 30 parts of oyster, 8 to 15 parts of Chinese thorowax root, 5 to 10 parts of processed rhizoma corydalis, 6 to 10 parts of green tangerine peel, 10 to 20 parts of radix scrophulariae, 10 to 15 parts of common pleione pseudobulb and 6 to 10 parts of processed jackinthepulpit tuber. The medicine is designed on the bases of the traditional theory of traditional Chinese medicine and summery of exploration for years; practice has proved that the medicine has reasonable compatibility and good synergy, realizes simultaneous treatment of principal and subordinate symptoms, can effectively treat breast diseases like plasma cell mastitis, hyperplasia of mammary glands, acute mastitis and mammary fibroma, has a high cure rate and enables cured diseases not to easily recur. Moreover, the medicine is a purely traditional Chinese medicinal preparation and has the advantages of simple and easily practicable treatment process, capacity of reducing pain of patients and no toxic and side effects.

The invention discloses a novel Chinese traditional medicine preparation for treating hyperplasia of mammary glands and a method for preparing the same, which belongs to the technical field of Chinese traditional medicine preparations. The Chinese traditional medicine preparation is extracted from the following natural Chinese herbal medicines in portion by weight: 10 to 20 portions of radix bupleuri, 12 to 24 portions of radix paeoniae alba, 10 to 20 portions of rhizoma atractylodis macrocephalae, 12 to 24 portions of chinese angelica, 12 to 24 portions of tuckahoe, 12 to 24 portions of gardenia, 5 to 10 portions of mint, 10 to 20 portions of liquorice, and the like, wherein the materials are prepared into capsules, granules or tablets according to the prior preparation process. Clinical studies prove that the novel Chinese traditional medicine preparation has the efficacies of soothing liver and qi stagnation, softening hardness to dissipate stagnation, and regulating vital energy and invigorating blood circulation, can be applied to treating diseases of hyperplasia of mammary glands, fibroadenoma of breast, and the like, has certain effect of improving the mood of a sufferer, increasing the appetite and improving sleeping, and has no obvious untoward effects and good safety; besides, the adoption of the novel Chinese traditional medicine preparation can lighten the economic burden of sufferers.

A uterine fibroid treatment device providing for localized delivery of one or more treatment drugs for treating various uterine conditions including, for example, uterine fibroids, abnormal uterine bleeding, pelvic adhesions and endometriosis. Generally, the uterine treatment device comprises a physical positioning element that can be inserted, positioned and maintained in close proximity to the uterine tissue to be treated. The treatment drugs delivered to the treatment location can include various combinations of anti-proliferative agents and angiogenesis inhibitors to provide different treatments concurrently. In some embodiments, the physical element can also serve the dual purpose of delivering the treatment drugs while simultaneously cutting off blood flow to a mature fibroid to initiate hypoxic / ischemic conditions within the mature fibroid.

The invention discloses a Chinese medicinal composition for treating a superficial tumor, which comprises the following components by mass: 10 to 30 grams of java brucea fruit; 10 to 30 grams of walnut kernel; 8 to 15 grams of unprocessed rhizoma pinelliae; 8 to 15 grams of common burreed rhizome; 3 to 8 grams of calomel; 3 to 8 grams of frankincense; 3 to 8 grams of myrrh; and 1 to 2 grams of polythrinicium. The medicinal composition is prepared by grinding the raw material medicaments respectively, uniformly mixing the powders and putting the powder into bottles. When the Chinese medicinal composition is used, the raw material medicaments are prepared into a paste by adding the right amount of white vinegar; and the paste is externally applied to affected parts of the tumor to block blood supply around the tumor to make the tumor die naturally. Clinical application shows that the Chinese medicinal composition has obvious curative effect on hemangioma, thyroidtumor and neurofibroma; a few scars are left after healing, but can be faded out gradually in the future; and the facial region is recovered well.

The invention relates to an ointment composition for treating breast diseases. The ointment composition consists of the following components in parts by weight: 1-5 parts of semen strychni, 1-5 parts of borneol, 2-10 parts of scorpio, 2-10 parts of tsaoko amomum fruits and 2-10 parts of radix ranunculi ternati. The invention also discloses an application and a preparation method of the ointment composition for treating the breast diseases. The ointment composition for treating the breast diseases provided by the invention has a good curative effect on various breast diseases such as mastitis, breast lumps, hyperplasia of mammary glands, breast fibroma, breast cysts, breast cancer and the like; and the ointment composition can achieve an effective treatment purpose through external application of traditional Chinese medicines, so that the trouble of taking medicines and the pain of accepting pains of patients can be avoided.

A pharmaceutical formulation and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as dimethylsulfoxide; a dye containing a chelated metal, such as hematoporphyrin; and an aromatic redox compound, such as benzoquinone. The pharmaceutical formulation is used effectively to stimulate periapical bone regeneration and for the endodontic treatment of periapical bone abscess, and fibromas, in a patient.

The present invention relates to the field of medicine, provided herein are novel nitrogenous heterocyclic compounds, their preparation methods and their uses as drugs, especially for treatment and prevention of tissue fibrosis. Also provided herein are pharmaceutically acceptable compositions comprising the nitrogenous heterocyclic compounds and the uses of the compositions in the treatment of human or animal tissue fibrosis, especially for human or animal renal interstitial fibrosis, glomerular sclerosis, liver fibrosis, pulmonary fibrosis, peritoneal fibrosis, myocardial fibrosis, dermatofibrosis, postsurgical adhesion, benign prostatic hyperplasia, skeletal muscle fibrosis, scleroderma, multiple sclerosis, pancreatic fibrosis, cirrhosis, myosarcoma, neurofibroma, pulmonary interstitial fibrosis, diabetic nephropathy, alzheimer disease or vascular fibrosis.

The invention relates to the field of Chinese medicinal preparations, especially a Chinese medicinal composition for treatment of mammary fibroma, a preparation method and application thereof. The composition comprises the following bulk drugs: 5-12 parts by weight of fructus liquidambaris, 3-10 parts by weight of malt, 5-10 parts by weight of radix curcumae, 1-5 parts by weight of centipede, 1-5 parts by weight of toad, 2-8 parts by weight of pangolin, 4-12 parts by weight of Cordyceps, 2-10 parts by weight of Sculellaria barbata, 1-6 parts by weight of ground beetle, 2-8 parts by weight of Ligusticum chuanxiong Hort, 3-10 parts by weight of Cowherb Seed, 2-10 parts by weight of Solanum dulcamara, 2-10 parts by weight of Codonopsis pilosula, 2-10 parts by weight of peach kernel, 3-10 parts by weight of Angelica sinensis, and 2-10 parts by weight of birthwort root. The Chinese medicinal composition provided by the invention has the characteristics of good curative effect, high cure rate and low recurrence rate in treatment of mammary fibroma diseases.

The invention discloses a traditional Chinese medicine composition for treating fibroma. The composition comprises air potatoes, lycopodium clavatum, cynanchum glaucescens, rhizoma sparganic, curcuma zedoary, olibanum, myrrh, patrinia, raw pinellia ternate, ligusticum wallichii and liquorice. The traditional Chinese medicine composition is high in bioavailability, quick to release drugs and quick to response and is obvious in effect for treating fibroma.

A Chinese medicine in the form capsule for treating mastoplasia and mastofibroma is prepared from 12 Chinese-medicinal materials including scrophularia root, red sage root, dandelion herb, white peony root, etc. Its preparing process is also disclosed.