The invention discloses a traditional Chinese medicine preparation for treating breast cancer and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following raw materials by weight: 5 to 30 parts of baikal skullcap root, 5 to 30 parts of red paeonia, 5 to 30 parts of tree peony bark, 10 to 50 parts of cortex albiziae, 5 to 30 parts of fried gardenia, 10 to 50 parts of trumpet creeper, 5 to 30 parts of plum flower bud, 10 to 50 parts of Glehnia Root, 10 to 50 parts of ruddle, 10 to 50 parts of fried Rhizoma Atractylodis Macrocephalae, 5 to 30 fried parts of radix bupleuri, 5 to 30 parts of roasted pangolin, 10 to 50 parts of turtle shell, 10 to 50 parts of Viscum album, 10 to 50 parts of windpipe, 10 to 50 parts of fingered citron, 10 to 50 parts of date and 5 to 30 parts of broiled liquorice. The invention has the efficacies of heat and toxic material cleaning, soften hard lump softening and node dispelling, qi tonifying, blood nourishing, heart calming and mind tranquilizing, is used for treating breast cancer which pents up scorchingly hot, losses qi and blood and invaginates pathogenic toxin. The breast cancer has the symptoms that breast lumps enlarge to extend to chests and the upper parts and the lower parts of clavicles, and are even transferred to liver, lung, skeletons and brains. Besides, the breast cancer has the symptoms of palpitation, mental fatigue, hypodynamia, sleeplessness, night sweat, diarrhea, clear abundant urine, dull tongue with whitish and greasy coating, and forceless deep and thready pulse. The traditional Chinese medicine preparation for treating breast cancer has effective curative effect and is safe and nontoxic.