49 results about "Breast cancer screening" patented technology

A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.

A method of screening for breast cancer, comprising: testing a plurality of asymptomatic women by measuring at least one electrical impedance characteristic on at least one breast, said asymptomatic woman being classified as belonging to a first group having a first risk factor for breast cancer; and re-classifying some of the women as belonging to a second group having a second risk factor greater than the first risk factor, based on the at least one impedance characteristic, wherein the second group has a risk factor of at least twice that of the first group, but less than 15 times that of the first group; and wherein fewer than 60% of those in the first group that have breast cancer are reclassified into the second group.

X-ray mammography has been the standard for breast cancer screening for three decades, but offers poor statistical reliability; it also requires a radiologist for interpretation, employs ionizing radiation, and is expensive. The combination of multiple independent tests, performed effectively at the same time and co-registered, can produce substantially more reliable detection performance than that of the individual tests. The multi-sensor approach offers greatly improved reliability for detection of early breast tumors, with few false positives, and also can be designed to support machine decision, thus enabling screening by general practitioners and clinicians; it avoids ionizing radiation, and can ultimately be relatively inexpensive.

A medical breast-image capturing apparatus includes an aperture member for exposing a breast of a test subject. To perform adequate breast cancer screening, the aperture member has a noncircular shape, is arranged to be replaceable with another aperture member, or has a variable opening. Another medical breast-image capturing apparatus includes a pressure-reducing device for reducing a pressure in a hollow section in which a breast is exposed.

The invention relates to a system for breast cancer screening and a corresponding method carried out with the system, the method comprising the following steps:

• • a) providing an image of a predetermined region of a breast of a woman,
  • b) determining the glandular volume in the scanning image, and
  • c) calculating the absolute glandular tissue amount of the breast from the glandular volume,
  • wherein the absolute glandular tissue amount can be used as a risk index which provides an indication about the risk of the woman of having breast cancer.

A method for selecting a breast cancer patient for therapy with an agent that reduces production of angiotensin II, for example an ACE inhibitor or renin inhibitor, comprises (a) determining whether the cancer comprises a tumor that is estrogen receptor positive (ER+) and (b) selecting the patient for such therapy only if the cancer is determined to comprise an ER+ tumor. A method for treating breast cancer in a patient further comprises (c) administering to the patient, if so selected, an agent that reduces production of angiotensin II, for example an ACE inhibitor or renin inhibitor. A method for treating a breast tumor in a patient having SERM-resistant ER+ breast cancer comprises administering to the patient an agent that reduces production of angiotensin II, for example an ACE inhibitor or renin inhibitor. A therapeutic combination useful in treatment of a breast tumor comprises an agent that reduces production of angiotensin II, for example an ACE inhibitor or renin inhibitor, and a second agent that comprises (a) an aromatase inhibitor or (b) an estrogen receptor modulator or antagonist.

What is disclosed is a system and method for detecting cancerous tissue in breast tissue using a thermal image. In one embodiment, the present tumor detection method involves selecting a region of interest in the thermal image to be processed for breast cancer screening. Thereafter, a percentage of pixels p₁ in the selected region having a temperature T_pixel¹, where T₁≦T_pixel¹≦T₂, is determined. A percentage of pixels p₂ in the selected region having a temperature T_pixel², where T₃T≦T_pixel², is determined. A ratio p₃=P_edge/P_block is also determined, where P_edge is a number of pixels around a border of a suspected tumor within the selected region, and P_block is a number of pixels in a perimeter of the selected region. A decision fusion rule R, as more fully disclosed herein, is utilized to determine, based on these determination whether tissue within that region is cancerous, or non-cancerous, or is suspicious of being cancerous.

The invention discloses a mammary gland ultrasonic screening method. The method comprises the steps of obtaining a depth image of a chest area of a user; performing model reconstruction according to the depth image to obtain a three-dimensional structure model of the area to be scanned, and generating a scanning track of an ultrasonic probe according to the three-dimensional structure model; controlling a scanning mechanism to drive the ultrasonic probe to perform ultrasonic scanning on the mammary gland area of the user according to the scanning track; and analyzing and processing the acquired ultrasonic image to generate a diagnosis result, and generating a reexamination plan and/or a health insurance scheme according to the diagnosis result. According to the mammary gland ultrasonic screening method, by means of an automation technology and an artificial intelligence technology, the low-cost and large-scale group mammary gland cancer screening becomes possible, the proportion of mammary gland cancer screening participated by the women of the right age in China can be greatly increased, and the mammary gland cancer prevention and control is facilitated.

What is disclosed is an apparatus for enabling privacy for patients undergoing breast cancer screening in a non-clinical setting. One embodiment of the present apparatus comprises an enclosure in which a person can remove one or more garments to expose their breasts to a thermal camera for breast cancer screening. The enclosure is such that at least the breast area of that person is shielded from view by third parties. The apparatus also comprises a thermal camera for capturing thermal images of the exposed breast area. The thermal camera is connected to a robotic arm that changes the camera angle relative to real-world coordinates so that thermal images can be taken of the breast area from any angle between a frontal view and a left/right lateral view. A processor which executes a software interface tool for semi-automated or automated breast cancer screening based on the thermal images of the breast.

Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.

The invention provides a nucleotide sequence as shown in SEQ ID No. 1 or SEQ ID No. 2, application of the nucleotide sequence and a breast cancer screening kit. The nucleotide sequence and the breast cancer screening kit can be used to assist clinical breast cancer diagnosis and are promising in clinical application prospect.

The invention relates to a breast cancer early diagnostic kit, which includes a capture prove, an amplification probe and a labeled probe aiming at mRNA detection of target genes. The target genes are a breast cancer screening gene and breast cancer CTC marker gene mRNA. Three molecular markers including a breast cancer screening gene, a breast cancer CTC marker gene and an exclusion gene are used together for early screening of breast cancer, so that the problem of a false-negative result due to expression difference of different individuals and different kinds of breast-cancer-related genes is solved and a false-positive result due to expression enhancement of some related genes in some other non-cancer diseases is excluded. The specificity and accuracy of the detection result are further improved, and misdiagnosis is prevented.

What is disclosed is a software tool which enables medical practitioners to manually or automatically analyze a thermal image of an area of breast tissue for the presence of tumorous tissue. In one embodiment, the software interface tool disclosed herein comprises a patient details object which enables the display of a patient details screen wherein a user can enter/edit patient information. A thermal analysis object enables a user to analyze a displayed thermal image of a breast of a patient for breast cancer screening and to classify tissue identified in the thermal image as being tumorous. A modalities object concludes the patient evaluation, persists all data collected from other sections of the tool, and generates reports for documentation purposes. The information can be captured from a database and edited and analyzed further using the tool. Also, report containing all the relevant data is generated for doctor's reference.

A method for evaluating mechanical anisotropy of a material sample to determine a characteristic of the sample includes interrogating a material sample a plurality of times. Each interrogation includes: applying a force having a direction, having a coronal plane normal to the direction of the force, and having an oval or other profile with long and short axes within the coronal plane, the long axis being oriented at a specified angle from a reference direction within the coronal plane; and measuring displacement of the material sample resulting from application of the force. The interrogations are taken at different angles of orientation within the coronal plane and different portions of the material sample are interrogated. For each measurement one or more parameters are calculated for the respective angle of orientation. A degree of anisotropy of the one or more parameters is determined and used to evaluate a characteristic of the material sample.

The invention discloses an automatic splicing method and system for an ABUS mammary gland ultrasonic panorama and a storage medium. The method comprises the following steps: firstly, identifying and marking a nipple position in an ABUS image by adopting an automatic nipple position positioning method; secondly, specifying the identified and marked nipple position as a feature matching point of a subsequent splicing algorithm; fitting transformation of the to-be-spliced image is carried out through the matching feature points; and finally, superposing and fusing the pictures by using a gradientweighting method, thereby realizing automatic splicing of the ABUS mammary gland ultrasonic panorama. According to the method, the ABUS mammary gland ultrasonic panorama can be effectively and automatically spliced; manual intervention, the defect that the whole mammary gland area cannot be completely presented due to the fact that the ABUS mammary gland ultrasonic image imaging view field is limited is overcome. A doctor can visually check the whole mammary tissue structure of an examined person at a time through the panorama, breast cancer screening cases can be more accurately and objectively diagnosed, and very important clinical application value is achieved.

What is disclosed is a system and method for automatically segmenting a breast from surrounding tissue in a thermal image. A thermal image of at least one breast of the patient is received. The thermal image is then analyzed to identify a set of N points around the breast, a contour of an outline of the body, and isotherms of the axilla and infra-mammary fold. Thereafter, the points are connected together to form a N-sided irregular polygon which segments the breast from surrounding tissue. Each of the points is a vertex of the polygon and comprises a draggable object which enables a user to selectively manipulate a shape of the polygon. A user can add/delete vertices from the polygon as desired. The area of the image encompassed by the polygon is communicated to a breast cancer screening algorithm performing automated or semi-automated screening.

The invention relates to the field of cancer detection, and in particular relates to a breast cancer screening blood detection kit and a detection method thereof. The invention provides the breast cancer screening blood detection kit and the detection method thereof. The detection kit comprises a box body and a lid. The box body comprises left and right chambers which are symmetrically left and right. The left chamber is divided into a left lower chamber and a left upper chamber. A support plate is arranged on the inner wall of the left upper chamber. An enzyme plate is placed on the support plate. A left heating wire is arranged on the bottom wall of the left upper chamber. An upper test tube rack and a lower test tube rack are arranged in the right chamber, wherein test tubes are placedon the upper test tube rack and the lower test tube rack. A right heating wire is arranged on the bottom wall of the right chamber. A water supply line used for supplying water to the left upper chamber and the right chamber is arranged in the left upper chamber. The breast cancer screening blood detection kit provided by the invention can provide necessary environmental conditions for detection,which makes a breast cancer screening system more complete. The operation is simpler, and test results are more accurate.

The invention provides a breast cancer screening marker composition, a selection method thereof and a breast cancer screening kit, and relates to the technical field of in-vitro diagnosis. According to the technical scheme, the breast cancer screening marker composition is hypermethylated in breast cancer and hypomethylated in white blood cells, and has a methylation sensitive incision enzyme digestion site; by utilizing the characteristic that methylation sensitive incision enzyme cannot cut methylation sites, non-tumor-source cfDNA is degraded, and tumor-source ctDNA is specifically amplified, so that the detection sensitivity is greatly improved; and the marking composition is small in quantity, simple to operate and short in time consumption. The breast cancer is detected and checked more accurately and effectively, so that the death rate of the breast cancer is reduced, and damage of the breast cancer to women is reduced.