47 results about "Chaenomeles" patented technology

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine composition for treating cervical spondylotic radiculopathy and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20 to 40 parts of radix puerariae, 5 to 25 parts of cassia twig, 20 to 40 parts of ramulus mori, 5 to 25 parts of notopterygium root, 20 to 40 parts of radix astragali seu hedysari, 20 to 40 parts of radix salviae miltiorrhizae, 5 to 25 parts of rhizoma chuanxiong, 5 to 25 parts of radix angelicae sinensis, 20 to 40 parts of radix paeoniae alba, 5 to 25 parts of radix clematidis, 5 to 20 parts of radix notoginseng, 2 to 10 parts of flos carthami, 5 to 25 parts of fructus chaenomelis lagenariae, 5 to 25 parts of earthworm, 20 to 40 parts of caulis spatholobi and 5 to 25 parts of pericarpium citri reticulatae. The traditional Chinese medicine composition disclosed by the invention is precise and reasonable in formula, standard and feasible in preparation process, free of any hormone, preservative and additive, and high in safety as natural raw materials are selected.

The invention discloses a compound scar ointment and a preparation method thereof, the ointment is prepared by decocting and concentrating Chinese herbal medicines such as salvia miltiorrhiza, cassia twig, radix paeoniae alba, rheum officinale, radix sophorae flavescentis, pepper, folium artemisiae argyi, lycopodium clavatum, garden balsam stem, pawpaw and borneol as raw materials and adding a matrix. The ointment has the effects of promoting blood circulation to remove blood stasis, relaxing tendons, activating collaterals, clearing heat and eliminating dampness, can effectively inhibit scar hyperplasia and promote scar softening and dissipation, and is suitable for treating various scars and acne marks. The ointment is simple in preparation process, green and environment-friendly, safe and non-irritant to use, good in clinical effect and wide in application prospect.

The present invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for anti-HPV virus and its related applications. As a medicine for the treatment and prevention of HPV infection, the traditional Chinese medicine composition takes clearing heat and detoxifying, expelling toxins outwards, removing stasis and promoting new growth as the main treatment principles, and comprises the following raw materials: indigo naturalis, coptis chinensis, polygonum cuspidatum, talc, astragalus membranaceus, liquorice, saxicola undulata, gleditsia sinensis thorn, bletilla striata, chaenomeles sinensis, dragon's blood and borneol. The composition of the present invention has been clinically used for more than 5 years and is found to have a good effect on clearing high-risk HPV infection in the cervix and vagina. The clearance rate can reach more than 80% after 3 to 6 months of clinical local medication, indicating that the traditional Chinese medicine composition has an anti-HPV virus effect. After being wrapped by nanomaterials, the traditional Chinese medicine composition can effectively protect the active molecule while slowly and continuously exerting its efficacy, effectively clearing the cervix and playing an anti-HPV virus role.

This invention relates to a highly effective pain-relieving pharmaceutical composition, comprising, by weight, 10-30 parts of Angelica sinensis, 10-30 parts of Chaenomeles speciosa, 10-30 parts of Paeonia lactiflora, 10-30 parts of Boswellia carterii, 10-30 parts of Eupolyphaga sinensis, 5-20 parts of Sappanwood, 5-20 parts of Carthamus tinctorius, 0.1-5 parts of Dracaena cochinchinensis, 5-20 parts of Syzygium aromaticum, 20-40 parts of Hibiscus mutabilis leaf, 20-40 parts of Citrus aurantium, 10-25 parts of Commiphora myrrha, and 20-40 parts of calcined natural copper. The pharmaceutical composition of this invention has advantages such as rapid onset of action, high therapeutic efficacy (≥96%), high significant efficacy (≥65%), low recurrence rate, prolonged recurrence interval, safety and effectiveness, and good patient compliance.

The invention discloses a preparation method of a traditional Chinese medicine external formula with a bone fracture rehabilitation effect. The preparation method comprises the following steps: step 1, preparing a traditional Chinese medicine extract; the preparation method comprises the following steps: 1, weighing the following raw material medicines in proportion: radix clematidis, cortex mori radicis, flos carthami, radix stephaniae tetrandrae, herba lycopodii, fructus liquidambaris, radix gentianae macrophyllae, radix saposhnikoviae, radix angelicae sinensis, radix angelicae dahuricae, fructus chaenomelis, vinegar-processed rhizoma corydalis, poria peel, processed frankincense and processed myrrh; 2, the raw material medicines are smashed and then mixed or the raw material medicines are mixed and then smashed, and a mixture is obtained.On the basis of the PCT concept, in-vitro shock wave treatment and an external formula are applied to treatment of a patient suffering from plantar fasciitis, compared with single in-vitro shock wave treatment, the inflammatory factor level can be better reduced through combination of the in-vitro shock wave treatment and the external formula, and the curative effect is better. Meanwhile, the production method of the external use formula disclosed by the invention is few in steps and simple to operate.

The invention provides a traditional Chinese medicine composition for treating alopecia areata and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from the following components in parts by mass: 10 to 30 parts of radix rehmanniae recen, 10 to 30 parts of radix rehmanniae preparata, 10 to 30 parts of caulis spatholobi, 10 to 30 parts of caulis polygoni multiflori, 30 to 50 parts of radix astragali, 10 to 20 parts of rhizoma chuanxiong, 10 to 30 parts of radix paeoniae alba, 5 to 20 parts of rhizoma gastrodiae, 5 to 20 parts of cordyceps sinensis, 10 to 30 parts of herba ecliptae, 10 to 30 parts of mulberry and 5 to 20 parts of fructus chaenomelis. The effect is stronger, and no side effect exists. The tincture prepared by the invention is a pure external preparation without systemic toxicity, has no side effects such as hirsutism and skin atrophy after long-term use, and is especially suitable for sensitive scalp patients.

The invention relates to a traditional Chinese medicine composition for treating rheumatic bone pain and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for treating rheumatic bone pain is prepared from the following raw materials: radix aconiti, radix aconiti agrestis, alpine yarrow herb, ardisia crenata, akebiaquinata, pawpaw, garden balsam stem, eucommia ulmoides, ligusticum chuanxiong hort, radix saposhnikoviae, radix stephaniae tetrandrae, caulis spatholobi, lycopodium clavatum, radix clematidis and radix bupleuri. The traditional Chinese medicine composition disclosed by the invention has the treatment effects of clearing and activating the channels and collaterals, dispelling wind and eliminating dampness, and warming channels and relieving pain, is mainly used for treating gout, waist and knee crymodynia, rheumatic arthritis, numbness of limbs and the like, and has relatively high effective rate.

The invention provides a preparation method and application of a chaenomeles speciosa leaf multi-effect refined extract. The method comprises the following steps: extracting with an ethanol solution, filtering, concentrating and drying to obtain the multiple-effect chaenomeles speciosa leaf fine extract. The refined extract has relatively strong antioxidant activity, antibacterial activity and hypoglycemic activity, and the antioxidant activity is three times that of vitamin C. The compound can be used for preparing antioxidative, antibacterial and hypoglycemic drugs. Or can be used for preparing wash supplies; or is used for preparing an external preparation for external antibiosis and anti-inflammation; or can be used for preparing food or medicine additives. The preparation technology of the refined extract is simple, safe and reliable, the prepared refined extract is high in yield, active ingredients are not prone to inactivation, and large-scale production is easy to expand.

The invention discloses a traditional Chinese medicine preparation for treating cervical vertebra and lumbar vertebra, and belongs to the technical field of traditional Chinese medicine preparations. The preparation is prepared from rhizoma polygonati, zaocys dhumnade, pawpaw, ginseng (artificially planted for less than five years), peach kernel, kudzuvine root, fructo-oligosaccharide and malt essence according to specific parts by weight through compatibility, the principle of'taking both symptoms and root causes into consideration and treating dialectically 'in traditional Chinese medicine is followed, and all the components act synergistically to jointly achieve the effects of tonifying liver and kidney, promoting blood circulation to remove blood stasis, relaxing tendons, dredging collaterals, relieving pain and relieving swelling. The preparation is a medicine and food homologous formula, is safe and non-toxic, adopts a solid beverage dosage form, is convenient to take, good in taste, stable in effective components and high in bioavailability, can quickly relieve pain, stiffness, numbness and other symptoms caused by cervical vertebra and lumbar vertebra degenerative diseases and chronic strain, can regulate the body constitution and delay the progress of the diseases after being taken for a long time, and has a good application prospect. The clinical application value and the market prospect are obvious.

The invention relates to a fingerprint establishment method and a detection method of a traditional Chinese medicine composition pink drink. The traditional Chinese medicine composition comprises the following raw materials: endothelium corneum gigeriae galli, pawpaw, hawthorn, chrysanthemum, orange peel, peach kernel and medlar. The fingerprint establishment method comprises the following steps: preparing a reference solution and a test solution; detecting the reference substance solution and the test solution by high performance liquid chromatography; a mobile phase adopted by the high performance liquid chromatography is an acetonitrile and phosphoric acid aqueous solution, and the elution mode is gradient elution.

The invention provides a traditional Chinese medicine composition for clearing heat, dispersing blood stasis and treating osteoarthritis as well as a preparation method, application and related products of the traditional Chinese medicine composition, and belongs to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition is prepared from rhizoma smilacis glabrae, honeysuckle flowers, radix astragali, fructus gardeniae, rhizoma polygoni cuspidati, radix paeoniae rubra, radix salviae miltiorrhizae, rhizoma atractylodis, vinegar-processed rhizoma curcumae, fructus chaenomelis The rhizoma smilacis glabrae has the effects of detoxifying and promoting diuresis, the honeysuckle has the effects of clearing away heat and toxic materials, and the astragalus membranaceus has the Gardenia, polygonum cuspidatum, radix paeoniae rubra and salvia miltiorrhiza help the monarch drug to clear heat, cool blood, promote blood circulation and dredge collaterals and serve as ministerial drugs; the rhizoma atractylodis has the effects of eliminating dampness and preventing cold and cold obstructing dampness, the vinegar-processed curcuma zedoary has the effects of breaking blood and promoting qi circulation and enhancing the blood activating efficacy, and the pawpaw has the effects of resolving dampness and relaxing tendons and aims at joint, tendon and vessel contracture; gastrodia elata can calm liver wind, dispel wind and dredge collaterals, and introduce the efficacy into meridian joints to serve as a conductant drug. The whole formula has the effects of clearing away heat and toxic materials, promoting diuresis and dredging collaterals, promoting blood circulation to remove blood stasis, tonifying qi and strengthening the body resistance, effectively improves the treatment effect on rheumatoid arthritis, and has the treatment effect on gouty arthritis.

The invention belongs to the field of biological medicine, and particularly discloses a traditional Chinese medicine acupoint patch for treating peripheral facial paralysis and a preparation method thereof. The traditional Chinese medicine composition is prepared from 14 raw materials including radix paeoniae alba, scorpio, pawpaw and the like according to a specific ratio, and is characterized in that firstly, supercritical CO2 is adopted for extracting fat-soluble components of snow lotus herb (40 DEG C / 25 MPa), enzymolysis is adopted for extracting radix paeoniae alba (albiflorin is larger than or equal to 90.3%), PLGA is adopted for wrapping hippocampus submicron powder (the encapsulation rate is larger than or equal to 85%), and active components are reserved to the maximum extent; (2) the acupoint patch is designed into a three-layer structure, middle-layer drug-loaded hydrogel is embedded into a soluble microneedle array (with the length of 800 microns) and pH response chitosan microspheres, and a composite penetration enhancer (azone + menthol) is added, so that temperature / pH dual intelligent drug release (the release speed is 2.8 times at the temperature of 35 DEG C, and the release speed is 3.1 times at the pH of 5.5) is realized; and (3) the nano pearl powder and the radix paeoniae alba extract are included by beta-cyclodextrin (the inclusion rate is greater than or equal to 91%), so that the stability is improved. Clinical verifications show that the total effective rate of combined western medicine treatment is 92%, which is significantly superior to that of a single western medicine group (76%, Plt; 0.05), and no new adverse reaction is generated.

The invention provides a 5 alpha-reductase inhibitor. The inhibitor is pawpaw total triterpenes (TCS). The invention also provides application of the pawpaw total triterpenes TCS in preparation of drugs for treating benign prostatic hyperplasia. TCS and UA have no obvious toxic and side effects on visceral organs of each group of rats; the thickness of glandular epithelial cells in a TCS group is remarkably reduced, the 5AR activity of the TCS group is remarkably reduced, the T level is remarkably reduced, and the DTH level is remarkably reduced; the blood sugar of the TCS group is obviously reduced, the concentration of total cholesterol and low-density lipoprotein is obviously reduced, and the TCS can obviously increase the high-density lipoprotein level and reduce the content of triglyceride. The results show that the TCS and the main component tartaric acid have a remarkable inhibiting effect on prostatic hyperplasia. The inhibition of 5AR activity and the reduction of DHT generation and T content are one of the action mechanisms, and the important characteristic is that the prostatic hyperplasia can be inhibited and abnormal blood sugar and blood fat can be regulated at the same time.

The invention discloses a beverage with blood activating and body warming effects and a preparation method thereof. The beverage with the effects of activating blood and warming the body is prepared from the following raw materials in parts by weight: 5-10 parts of coffee beans, 4-8 parts of sika deer antler blood powder, 4-8 parts of pawpaw, 4-6 parts of agaricus blazei murill, 2-4 parts of angelica sinensis, 1-3 parts of ginseng, 1-3 parts of polygonatum kingianum, 0.8-12 parts of sanchi flowers, 4-6 parts of dried ginger, 4-6 parts of cinnamon, 2-4 parts of L-cysteine, 0.8-1.2 parts of amomum tsao-ko and 2-4 parts of sugar. According to the drink with the effects of promoting blood circulation and warming the body, the drink has the effects of promoting blood circulation to remove meridian obstruction, warming the spleen and stomach for dispelling cold, strengthening tendons and bones, reinforcing vital energy, tonifying qi and yin, promoting salivation and nourishing blood and the like through limitation of all the natural plant raw materials and the dosage, and the effects of dispelling cold and warming the body can be achieved under the combined action of all the raw materials, so that the cold constitution can be improved, and the health of a human body is improved. Meanwhile, the drink with the effects of promoting blood circulation and warming the body, which is prepared by the application, is suitable for being drunk in winter, and the effect of quickly warming the body can be achieved.

Provided herein are methods and compositions for reducing and preventing pain. In some embodiments, the methods include administration of a composition to an individual experiencing pain, the composition including one or more of Incarvillea sinensis, Salix alba, Tanacetum parthenium, Petasites hybridus, papain, and bromelain.

This invention discloses a pharmaceutical composition, its formulation, and its application for treating rheumatic arthralgia. The pharmaceutical composition comprises the following components in parts by weight: 20-40 parts of Salvia miltiorrhiza, 10-20 parts of Paeonia lactiflora, 20-40 parts of Panax notoginseng rootlets, 10-20 parts of Ligusticum chuanxiong, 9-20 parts of Angelica sinensis, 9-20 parts of Clematis chinensis, 9-20 parts of Angelica pubescens, 9-20 parts of Chaenomeles speciosa, 9-20 parts of Saposhnikovia divaricata, 9-20 parts of Achyranthes bidentata (processed with wine), and 9-20 parts of Carthamus tinctorius. Pharmaceutically acceptable excipients may be added to the pharmaceutical composition to prepare a formulation. The pharmaceutical composition and its formulation can be used to treat rheumatic arthralgia.

The invention discloses a traditional Chinese medicine composition with functions of regulating qi and promoting digestion, relates to the technical field of traditional Chinese medicines, and is technically characterized in that the traditional Chinese medicine composition is prepared from the following components in parts by weight: 3-10 parts of poria cocos, 3-10 parts of dried dendrobe, 5-15 parts of malt, 5-6 parts of pawpaw, 6-40 parts of codonopsis pilosula, 5-10 parts of bighead atractylodes rhizome, 4-6 parts of hawthorn, 3-6 parts of fructus forsythiae, 3-6 parts of massa medicata fermentata fujianensis, 3-6 parts of jujube and 3-6 parts of pericarpium citri reticulatae. According to the traditional Chinese medicine composition, various traditional Chinese medicines are combined together, the properties of the traditional Chinese medicines are mutually blended, the effects are more comprehensive, and the traditional Chinese medicine composition can enhance spleen and stomach functions, relieve dyspepsia, adjust gastrointestinal tract balance and induce diuresis to reduce edema; a plurality of components in various traditional Chinese medicines are matched with one another, so that the medicine properties of the various traditional Chinese medicines are enhanced, and the effects are better exerted.

The invention provides a foot bath bag composition and a preparation method thereof, and relates to the field of traditional Chinese medicinal materials. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 30 to 40 parts of fructus forsythiae, 35 to 45 parts of folium artemisiae argyi, 5 to 15 parts of flos carthami, 15 to 25 parts of caulis spatholobi, 25 to 35 parts of ramulus mori, 15 to 25 parts of herba leonuri, 15 to 25 parts of radix clematidis, 5 to 15 parts of fructus chaenomelis, 15 to 25 parts of rhizoma corydalis, 5 to 15 parts of caulis sargentodoxae, 5 to 15 parts of herba lycopodii, 15 to 25 parts of rhizoma chuanxiong and 5 to 15 parts of liquorice root. According to the traditional Chinese medicine composition, the traditional Chinese medicine composition is prepared by taking fructus forsythiae and folium artemisiae argyi as main components, extracting effective components through boiling, and absorbing the effective components in the composition through a foot bath mode, a sole Yongquan acupoint and skin, so that the traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis, diminishing inflammation and relieving pain, can effectively relieve pain caused by gonitis, femoral head necrosis and rheumatic arthritis, and is good in treatment effect.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition and a traditional Chinese medicine preparation for treating gouty arthritis and a preparation method and application of the traditional Chinese medicine composition and the traditional Chinese medicine preparation. The traditional Chinese medicine composition is prepared from, by mass, 2.5-5% of herba ephedrae, 7-8% of cassia twig, 7-8% of radix aconiti carmichaeli, 7-8% of radix saposhnikoviae, 7-8% of radix stephaniae tetrandrae, 9-9.8% of radix clematidis, 7-8% of scorpio, 7-8% of pawpaw, 11.5-14.8% of radix cyathulae and 7-8% of nidus vespae. 14.5-15.8% of rhizoma dioscoreae septemlobae and 4-5% of radix glycyrrhizae; the traditional Chinese medicine components are used for rapidly relieving red, swollen and hot pain of joints and improving intractable joint pain, stiffness and unfavorable flexion and extension. The traditional Chinese medicine composition has the advantages that the effect of reducing the serum inflammatory factor level of a gouty arthritis patient is obvious, the pain symptom can be effectively relieved, the red, swollen and heat pain of joints can be quickly relieved, and the intractable joint pain, stiffness and unfavorable flexion and extension are improved.

The invention discloses a traditional Chinese medicine composition for treating Bell paralysis sequelae. The traditional Chinese medicine composition is prepared from the following raw material medicines: astragalus membranaceus, angelica sinensis, radix rehmanniae preparata, ligusticum wallichii, parched white peony root, kudzu vine root, cortex albiziae, pawpaw, semen coicis, lycopodium clavatum, caulis spatholobi and angelica dahurica. The invention further discloses a traditional Chinese medicine compound preparation for treating the Bell paralysis sequelae and application of the traditional Chinese medicine composition or the traditional Chinese medicine compound preparation to preparation of medicine for treating the Bell paralysis sequelae. The traditional Chinese medicine composition has a remarkable curative effect on Bell facial paralysis sequelae such as mouth-eye linkage, facial spasm and facial muscle tension and weakness, can remarkably relieve facial tension, relieve mouth-eye linkage, relieve facial spasm and improve the living quality and mental state of a patient, is remarkable in treatment effect, can adjust and add or reduce the formula according to specific diseases, and is free of toxic and side effects. The method has great popularization and application values.

The invention discloses a traditional Chinese medicine composition for treating osteoarthritis, and belongs to the technical field of traditional Chinese medicines. In the traditional Chinese medicine composition, monarch drugs are radix angelicae pubescentis and processed semen strychni; ministerial drugs comprise radix aconiti preparata, tripterygium wilfordii, radix clematidis and rhizoma drynariae; the adjuvant drugs comprise kadsura pepper stem, liquidambar formosana hance, pawpaw, rhizoma dioscoreae nipponicae, frankincense, ground beetle, herba epimedii, teasel root, herba siegesbeckiae and lycopodium clavatum; and the conductant drug is coix seed. The whole formula is monarch, minister, assistant and guide, cooperates with each other, is rigorous in formula, has the effects of dispelling wind and eliminating dampness, warming channels and expelling cold, removing stasis and diminishing swelling, relaxing tendons and dredging collaterals, and tonifying kidney and strengthening liver, can remove arthralgia of knee and ankle joints and recover functions, can be used for treating osteoarthritis, and has a wide application prospect.

This invention provides the application of wrinkled papaya polyphenols in the preparation of drugs for treating osteoarthritis. The wrinkled papaya polyphenols are used in the preparation of drugs that reduce the release of pro-inflammatory cytokines and the inflammatory mediator NO in primary chondrocytes, and / or reduce the mRNA expression of inflammation-related enzymes, and / or inhibit the phosphorylation of proteins related to the NF-κB signaling pathway. To test and clarify the anti-inflammatory effect of wrinkled papaya polyphenols, an ADTC5 primary chondrocyte inflammation model was constructed for observation. The results showed that wrinkled papaya polyphenols significantly inhibited IL-1β-induced inflammation in ADTC5 primary chondrocytes, effectively reduced the secretion of pro-inflammatory cytokines (IL-6 and TNF-α), inhibited the release of the inflammatory mediator NO, downregulated the mRNA expression of inflammatory enzymes (iNOS and Cox-2), and reduced the phosphorylation of IκBα and p65 proteins.

The invention provides a preparation method and application of a traditional Chinese medicine composition for growing and nourishing hair, and belongs to the technical field of traditional Chinese medicines. In the formula, prepared rehmannia root and prepared fleeceflower root are used as monarch drugs, wine-processed glossy privet fruit, dodder and refined sealwort are used as ministerial drugs, ligusticum wallichii, peach kernel, safflower and white peony root are used as adjuvant drugs, and notopterygium root and pawpaw are used as conductant drugs. According to the traditional Chinese medicine composition for growing and nourishing hair, through mutual cooperation of pure natural traditional Chinese medicine raw materials, hair output of existing hair follicles can be promoted, the unit number of functional hair follicles can be increased in the modes of improving the microenvironment of the hair follicles, activating dormant hair follicles and the like, and the purposes of growing hair and nourishing hair are achieved; and the risk of relapse of alopecia is effectively reduced.

This invention provides a traditional Chinese medicine composition for treating or improving asthma, relating to the field of traditional Chinese medicine pharmaceutical technology. The composition comprises the following raw materials: Inula japonica, Bambusa textilis, Lysimachia christinae, Rutaecarpa, Ligusticum striatum, Pyrrosia lingua, Chaenomeles speciosa, Dioscorea hypoglauca, Atractylodes lancea, walnut kernel, maltose, Citronella arvense, and Glycyrrhiza uralensis. In this invention, each ingredient in the composition fulfills its specific function, addressing both the symptoms of asthma (phlegm and qi stagnation, and upward flow of lung qi) and the underlying causes (spleen strengthening, kidney tonification, and liver soothing). This achieves the combined effects of dispelling wind and clearing the lungs, resolving phlegm and descending rebellious qi, strengthening the spleen and resolving dampness, warming the kidneys and promoting qi circulation, and regulating liver qi. It treats both the symptoms and the root cause. This invention's composition effectively inhibits airway inflammation in asthma model mice, improves clinical symptoms, and demonstrates significant therapeutic effects. The composition exhibits a high overall effective rate in treating asthma, with particular advantages in alleviating clinical symptoms and improving lung function in asthma patients.

The invention belongs to the technical field of traditional Chinese medicine identification, and particularly relates to a method for distinguishing and identifying two traditional Chinese medicinal materials, namely, Chaenomeles sinensis (Thouin Koehne) and Chaenomeles speciosa (Sweet Nakai). The invention further relates to a method for distinguishing and identifying the two traditional Chinese medicinal materials, namely Chaenomeles sinensis (Thouin Koehne) and Chaenomeles speciosa (Sweet Nakai). According to the method, two traditional Chinese medicinal materials are identified by adopting 3-O-acetyl ursolic acid as a reference substance through the steps of ultrasonic extraction and thin-layer chromatography, so that the identification of easily-confused medicinal materials of the two traditional Chinese medicinal materials can be realized. The method can quickly realize the distinguishing of the chaenomeles speciosa and chaenomeles speciosa samples as traditional Chinese medicinal materials. The method has the characteristics of convenience, feasibility and rapidness, and is wide in applicability.

The invention discloses a traditional Chinese medicine composition and traditional Chinese medicine ointment for treating temporomandibular joint disorder, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for treating temporomandibular joint disorder is prepared from the following raw materials in parts by weight: 20 to 30 parts of herba lycopodii, 15 to 25 parts of herba speranskiae tuberculatae, 10 to 15 parts of radix angelicae sinensis, 15 to 25 parts of rhizoma chuanxiong, 12 to 16 parts of radix clematidis, 18 to 26 parts of radix saposhnikoviae, 5 to 10 parts of flos carthami, 6 to 9 parts of fructus chaenomelis lagenariae, 10 to 15 parts of herba aristolochiae mollissimae and 5 to 10 parts of ramulus cinnamomi. The traditional Chinese medicine composition is reasonable in compatibility, rich in raw materials and effective in combination of the components, has the effects of dispelling wind, eliminating dampness, relaxing tendons, activating collaterals, eliminating arthralgia and relieving pain, is effectively used for treating the temporomandibular joint disorder, is convenient to use and good in effect, is an innovation of medicines for treating the temporomandibular joint disorder, and has good popularization and application values and practical clinical significance.

The utility model relates to the field of papaya fruit vinegar production, and discloses a crushing device for papaya fruit vinegar production, which comprises a box body I, a feed port, a discharge port, a placing plate, a mounting plate, a cutting blade, a linear driving part I, an angle adjusting mechanism, a guide assembly, a box body II, a discharge hole, a cover body, a crushing assembly and a height adjusting mechanism. According to the papaya chopping device, through the mutual cooperative use of the structures, the effect that papaya is cut into a plurality of small blocks, and then the diced papaya is smashed can be achieved, labor can be saved, and efficiency can be improved.

The present invention provides a traditional Chinese medicine composition for treating chemotherapy-induced peripheral neuropathy, its preparation and application. The traditional Chinese medicine composition of the present invention comprises traditional Chinese medicines in the following weight ratios: 15-25 parts of Angelica sinensis, 10-20 parts of Paeonia lactiflora, 8-12 parts of Cinnamomum cassia, 4-6 parts of Asarum sieboldii, 8-12 parts of Glycyrrhiza uralensis, 4-6 parts of Tetrapanax papyriferus, 15-25 parts of Spatholobus suberectus, 25-35 parts of Astragalus membranaceus, 8-12 parts of Liquidambar formosana, 10-20 parts of Codonopsis pilosula, 8-12 parts of Chaenomeles sinensis, 8-12 parts of processed Aconitum carmichaelii, and 25-35 parts of Ziziphus jujuba. In the formula, Angelica sinensis is sweet and warm, nourishing blood and regulating blood; Cinnamomum cassia is pungent and warm, warming the meridians to dispel cold and warming and dredging blood vessels, serving as the monarch drug. Processed Aconitum carmichaelii and Asarum sieboldii warm the meridians to dispel cold, assisting Cinnamomum cassia in warming and dredging blood vessels so that yang qi reaches the four extremities; Paeonia lactiflora nourishes blood and regulates nutrient qi, assisting Angelica sinensis in tonifying nutrient blood, and Astragalus membranaceus and Codonopsis pilosula strengthen the spleen and replenish qi, assisting Angelica sinensis in replenishing qi and generating blood, all serving as the ministerial drugs. Tetrapanax papyriferus dredges the meridians to promote blood circulation, and Spatholobus suberectus, Liquidambar formosana and Chaenomeles sinensis strengthen promoting blood circulation and dredging collaterals; Ziziphus jujuba and Glycyrrhiza uralensis replenish qi, strengthen the spleen and nourish blood, all serving as the adjuvant drugs. Treating chemotherapy-induced peripheral neuropathy with the traditional Chinese medicine formula of the present invention has good clinical curative effects.

The application discloses a traditional Chinese medicine composition for preventing and treating knee osteoarthritis and application thereof, and relates to the technical field of knee osteoarthritis treatment. The traditional Chinese medicine composition is Sanqiang Decoction which is composed of the following raw materials in parts by weight: Eucommia ulmoides leaves 90-150 parts, Chaenomeles speciosa 60-120 parts, Astragalus membranaceus 90-150 parts, Gastrodia elata 35-65 parts, Dendrobium 35-65 parts, Pueraria lobata 90-150 parts, Curcuma longa 35-65 parts, Persicae Semen 35-65 parts, Coix seed 60-120 parts, Fructus Corni 75-125 parts and calcium gluconate 9-15 parts. The Sanqiang Decoction in the application can improve the pathological state of cartilage and the microstructure parameters of subchondral bone of knee osteoarthritis, improve the antioxidant stress capacity, and improve the quadriceps atrophy caused by knee osteoarthritis, and has good pharmacological effects. The mechanism is related to the activation of TGF-beta 1 / Smad3, Nrf2-Keap1 and PI3K / AKT / FOXO1 pathways.

The application belongs to the technical field of medicine, and discloses a composition for treating hyperlipidemia and hyperglycemia and a preparation method thereof, which is composed of the following raw materials in parts by weight: 10-28 parts of Herba Portulacae, 10-25 parts of Chaenomelis Fructus, 5-12 parts of Rhizoma Polygonati, 5-10 parts of Valeriana jatamansi Jones, 0.5-3 parts of Illicium verum, 0.5-4 parts of Panax notoginseng, 1-5 parts of Crataegus pinnatifida and 2-8 parts of Pu'er tea. The preparation method comprises the following steps: S1, weighing and crushing the raw materials; S2, twice water extraction of the crushed Herba Portulacae, Chaenomelis Fructus, Illicium verum, Crataegus pinnatifida and Pu'er tea to obtain an extract; S3, ethanol extraction and then ethyl acetate extraction of the crushed Valeriana jatamansi Jones and Rhizoma Polygonati to obtain an extract; and S4, mixing the crushed Panax notoginseng, the extract obtained in S2 and the extract obtained in S3 to obtain the composition for treating hyperlipidemia and hyperglycemia. The composition has a significant effect of reducing blood lipid and blood sugar.