543results about How to "Strong medicine" patented technology

Medical systems and methods for treating kidney disease alone, heart failure alone, kidney disease with concomitant heart failure, or cardiorenal syndrome are described. The systems and methods are based on delivery of a chimeric natriuretic peptide to a patient. Methods for increasing peptide levels include direct peptide delivery via either an external or implantable programmable pump.

The invention relates to a medical used hot melt pressure-sensitive adhesive type base material and its preparing method which provides a hot melt pressure-sensitive adhesive and an adhesive used paste preparation. The main element of the hot melt pressure-sensitive adhesive is styrenic thermoplastic elastomer SIS (phenylethene -isoprene -phenylethene three block copolymers) with adhesive resin (such as petroleum resin, terpenes polymer, polyisobutylene), flexing oil (such as liquid petrolatum) and aging retarder (such as propyl gallate, BZ) and so on.

The invention relates, inter alia, to a method for reducing symptoms of, or for treating, one or more disorders or conditions wherein the dopaminergic system is disrupted, the method comprising administering to a host in need thereof an effective amount of a compound that is able to increase the ion flow through KCNQ potassium channels.

The invention relates to a DSPE-PEG2000-FA-modified nanometer paclitaxel liposome. A molar ratio of the DSPE-PEG2000-FA to egg yolk lecithin is 0.05% to 0.15%, and a particle size of the liposome is less than 150 nm. A preparation method of the DSPE-PEG2000-FA-modified nanometer paclitaxel liposome comprises the following steps: first, preparing a DSPE-PEG2000-FA into a DSPE-PEG2000-FA micelle; second, performing incubation on the phosphatidyl ethanolamine-polyethylene glycol2000-folic acid micelle and a paclitaxel liposome together to obtain a DSPE-PEG2000-FA-modified nanometer paclitaxel liposome. Materials, which are forbidden to be used in clinical practice, are not used as crude materials in the present invention. According to the invention, the DSPE-PEG2000-FA-modified nanometer paclitaxel liposome has a small particle size, and the content of the DSPE-PEG2000-FA is low; besides, the DSPE-PEG2000-FA-modified nanometer paclitaxel liposome has good drug entrapment efficiency and good colloid stability. Moreover, the DSPE-PEG2000-FA-modified nanometer paclitaxel liposome can be absorbed effectively by an ovarian cancer cell having properties of sensitiveness to folic acid (+) and drug resistance, and the cytotoxicity of folic acid dependence is displayed; therefore, the efficacy of the DSPE-PEG2000-FA-modified nanometer paclitaxel liposome is stronger than that of a paclitaxel injection.

The present invention relates to externally applied medicine for treating mastopathy. The medicine includes two componnets. The component A is prepared with over 20 kinds of Chinese medicinal materials including angelica, trogopterus dung, sea algae, bupleurum root, corydalis tuber, etc.; and the component A is prepared with dahurian angelica root, nutagrass flatsedge rhizome, frankincense, myrrh, rhubarb and other Chinese medicinal materials. The medicine is applied directly to the pathologic parts to take effect, so that it has fast effect and no influence on digestive system and internal secretion system.

The invention relates to a gel injection combining a molecular targeted drug and a cytotoxic drug. The gel injection comprises a small molecular targeted drug, a traditional cytotoxic drug, a temperature-sensitive material, a solvent and pharmaceutical excipients, wherein the temperature-sensitive material is selected from poloxamer, polylacticacid-polyethylene glycol-polylactic acid or polyglycolide lactide-polyethylene glycol-polyglycolide lactide and the like; the solvent is selected from water, brine salt or 5% glucose aqueous solution and the like, the prepared gel injection can be injected intratumorally or peritumorally, the anti-tumor effect is obvious, and the side effects are fewer.

The invention relates to a salve for the treatment of traumatism, contusion, alopecia areata as well as burn and scald, essentially solving the problems that drugs for curing traumatism, contusion, alopecia areata as well as burn and scald have single function, poor curative effects, easy wound infection and scars at the wound after recovery. The salve is characterized in that the salve is prepared by drugs according to the following weight ratio: 3 portions to 5 portions of calomeas, 8 portions to 10 portions of realgar, 8 portions to 12 portions of calamine, 5 portions to 9 portions of boswellia carteri, 5 portions to 9 portions of myrrh, 3 portions to 4 portions of borneol, 8 portions to 12 portions of resina draconis, 5 portions to 9 portions of catechu and 180 portions to 280 portions of vasogen for medical purposes. The salve has the effects of diminishing inflammation and detoxication, removing slough, heeling wounds, invigorating the circulation of qi and blood, reducing swelling and easing pain, disinfesting insects and eliminating toxic materials, promoting blood circulation and removing blood stasis, removing toxic substance and evacuating pus, promoting reunion of the fractured bones, promoting hair growth, repairing wound, promoting regeneration of skin and quickening tissue regeneration.

The invention discloses a blank liposome taking ginsenoside Rg3 or an analogue thereof as a membrane material, and a preparation method and application thereof. The ginsenoside as shown in the formulaI is blank liposome of a membrane material, wherein the blank liposome is provided with a membrane, and the membrane comprises lipid substances and the ginsenoside as shown in the formula I. The blank liposome disclosed by the invention has the characteristics of good film-forming property, encapsulation efficiency, targeting property, long circulation, stability, safety and uniformity, is used for encapsulating active substances, biological agents, polynucleotides or oligonucleotides in medicines and cosmetics to form the liposome loaded with the active substances, and is simple and convenient in preparation process.

The invention discloses compound low-concentration atropine eye drops and a preparation method thereof. The eye drops are mainly prepared from low-concentration atropine, lutein or a lutein derivative, fructus lycii, taurine, liquid pearl and multiple vitamins (A, B1, B6, B12 and E) by processing in a certain ratio. Drugs used in the compound eye drops conform to Chinese pharmacopoeia and United States Pharmacopeia, by means of functional collaborative treatment synergy of various natural drug active factors and atropine for vision, dose of atropine is reduced effectively, side effects on human eyes are reduced, ciliary muscle spasm can be eliminated, eyeball nutrition can be improved, asthenopia can be relieved, the eye drops have effects of improving eyesight and clearing away heat and toxic materials and have the capacity of enhancing human eye immunity and resisting eye diseases, the effect of preventing and treating myopia of adolescents and children is enhanced effectively, and the eye drops are high in safety, long in shelf life and good in biocompatibility with eye environment and has positive promotion and application values.

The invention discloses an ultrasonic controlled release medicine elution balloon catheter and a preparation method. The surface of the medicine elution balloon catheter is coated with a medicine coating, the medicine coating is composed of a fat-soluble medicine carrying microcapsule having a ultrasonic response characteristic and an adhesive having a water-soluble characteristic. Medicine of the medicine elution balloon catheter is wrapped in a lipophilic medicine carrying microcapsule which is hard to dissolve in the blood, so medicine loss caused by blood washing can be reduced. When the ultrasonic controlled release medicine elution balloon catheter is used, the medicine elution balloon catheter is sent to a lesion portion and unfolds, a balloon contacts with the lesion tissues, ultrasound inducts the lesion portion at the external, the medicine carrying microcapsule can be speeded up to be separated from the hydrophilic adhesive, medicine can diffuse in the fat-soluble lesion tissues, at the same time, the medicine carrying microcapsule having the ultrasonic response characteristic breaks under the function of the ultrasound and discharges the medicine, the efficiency of medicine absorption and utilization by the target lesion tissues can be greatly raised. The amount and time of medicine discharge can be controlled through adjusting the characteristic and the ultrasonic characteristic of the medicine carrying microcapsule, the validity and safety of the medicine elution balloon catheter can be improved.

The invention relates to the field of drugs, in particular to a preparation method of a sustained release preparation containing ibuprofen mini-pills. The technical problem to be solved is to provide the sustained release preparation containing ibuprofen mini-pills. A relative substance detection method is added for the medicament by our company by reference to the British Pharmacopoeia. The medical property of the medicament is released stably and lastingly, and the safety and effectiveness of the medicament are really achieved. The adopted technical is as follows: weighing the following raw materials in parts by weight: 25-35 parts of ibuprofen, 3-10 parts of milk sugar, 1-5 parts of microcrystalline cellulose, 1-5 parts of hydroxypropyl methylcellulose and 10-15 parts of medicinal ethanol; then mixing the materials and spraying an adhesive into the materials to obtain the ibuprofen sustained release preparation. The preparation method of the sustained release preparation containing ibuprofen mini-pills is widely applied to the pharmaceutical field of the ibuprofen.

The invention discloses a medicament for treating empyrosis, which comprises the following components in part by weight: 10 to15 parts of white chrysanthemum flower, 10 to 12 parts of pinellia tuber, 500 parts of calcined lime, 10 to 15 parts of borneol, 5 to 10 parts of rhubarb, 5 to 10 parts of lightyellow sophora root, 5 to 10 parts of amur corktree bark, 5 to 10 parts of catechu, 11 to 14 parts of golden thread, 10 to 15 parts of swordlike atractylodes rhizome, 60 to 100 parts of calcined calamine and 15 to 30 parts of garden burnet root. The components are crushed, mixed, sealed and buried underground for preserving for three years. In the medicament, the components are subjected to organic compatibility, and have the complementary effect to bring the optimal synergistic effect into play, so that the medicament has powerful medicinal effects of diminishing inflammation and reliving pain quickly, removing nidus of organisms effectively, and achieving an unexpected treatment effect.

A composite anticoccidial medicine for fowls is prepared from antifebrile dichroa root, bupleurum root, flavescent sophora root and sweet wormwood through cutting short, immersing in water, decocting three times while filtering, depositing in alcohol, filtering and sterilizing.

The invention belongs to the field of feeds for quails and particularly relates to Chinese-herbal-medicine feed for quails. The Chinese-herbal-medicine feed is characterized by comprising the following components in parts by weight: 40-60 parts of corn, 20-30 parts of soybean meal, 5-10 parts of super fish powder, 2-4 parts of soybean oil, 2-6 parts of grass seed powder, 5-10 parts of soybean oil cake residue, 5-10 parts of rice bran, 1-3 parts of salt, 10-15 parts of premix and 10-15 parts of traditional-Chinese-medicine additives. The Chinese-herbal-medicine feed has the beneficial effects that materials such as the corn, the bean meal and the grass seed powder with suitability for intaking of the quails, high digestibility and good palatability are selected according to the nutrition needed by growth and development of the laying quails, the nutrition is rich, the protein content is high, the energy is high, the nutrition needed by the laying quails is provided, the materials are easily digested and absorbed by the quails, the daily feed intake is increased and the egg laying capability is enhanced; a proper material matching ratio is determined by multiple testing, the most reasonable feed-egg ratio is ensured, and the raising income is largest; and the feed contains the components such as the premix and the traditional-Chinese-medicine additives, the types of nutritional elements are complete, and various nutritional components needed are provided, so that the healthy growth of the quails is ensured.

The invention provides chitosan-modified methazolamide solid lipid nanoparticles and a preparation method thereof. The chitosan-modified methazolamide solid lipid nanoparticles can be used as eye drops. The preparation method is suitable for industrial production. The chitosan-modified methazolamide solid lipid nanoparticles are characterized in that based on 30ml of a nanoparticle-containing solution, the chitosan-modified methazolamide solid lipid nanoparticles comprise 5mg of methazolamide, 25 to 150mg of at least one lipid material, 25 to 150mg of phospholipid, 5 to 100mg of chitosan, 50 to 250mg of at least one non-phospholipid surfactant and 50 to 250mg of at least one assistant surfactant. The chitosan-modified methazolamide solid lipid nanoparticles have small particle sizes and high drug entrapment efficiency. Compared with solid lipid nanoparticles which are not modified by chitosan, the chitosan-modified methazolamide solid lipid nanoparticles have higher stability and better corneal permeability because of positive charges on the surfaces of the chitosan-modified methazolamide solid lipid nanoparticles so that drug bioavailability is improved. Therefore, the chitosan-modified methazolamide solid lipid nanoparticles have a large clinical application potential in glaucoma treatment.

The invention relates to weight-reducing tea. The weight-reducing tea is mainly prepared from the following materials according to a certain weight ratio: lotus leaf, roselle calyx, lemon, sour orange, wild mint herb, ass-hide gelatin, lotus seeds, green tea, epigallo catechin gallate and xylooligosaccharide. The materials can be prepared into tea beverage, instant tea and teabag. The tea provided by the present invention has effects of qi promoting, body fluid regeneration, intestine moistening and bowel relaxing. The total effective rate of the tea for treating habitual constipations is more than 87%. In addition, the tea is easy to be drunk, and has significant treatment and health effects.

The invention discloses external application medicinal powder for treating lubar intervertebral disc protrusion, which consists of the following components by mass: 20 to 35g of szechuan lovage rhizome, 20 to 35g of Chinese angelica, 10 to 15g of peach seed, 10 to 15g of safflower, 10 to 15g of myrrh, 10 to 15g of trogopterus dung, 10 to 15g of liquoric root, 20 to 30g of incised notopterygium rhizome, 20 to 35g of largeleaf gentian root, 10 to 15g of nutgrass galingale rhizome, 10 to 15g of earthworm, 20 to 35g of twotooth achyranthes root, 10 to 15g of danshen root, 10 to 15g of common floweringquince fruit, 10 to 15g of eucommia bark, 30 to 45g of Chinese taxillus twig, 30 to 40g of clematis root, 10 to 15g of pangolin scales, 30 to 45g of black ant, 30 to 45g of williams elder twig and 10 to 15g of wild fagopyrum esculentum moench. The external application medicinal powder can invigorate blood circulation and promote flow of qi, remove pain, remove obstruction in channels, and free arthralgia to relieve pain, has the effects of insisting inflammation, easing pain and changing local tissue blood circulation, and achieves the effect of addressing both the symptoms and root causes.

The external medicine for treating traumatic injury with fast effect is prepared with eight kinds of Chinese medicinal materials including angelica, frankincense, myrrh, safflower, ledebouriella root, etc. as well as rosin and sesame oil. It has the functions of stopping pain, stopping itching, promoting blood circulation, elimianting blood clots, etc. It has high curative effect on tendon injury, sprain, fracture and other closed traumatic injury and has also certain curative effect on frostbite, scapulohumeral periarthritism tenosynovitis and hyperplasia of mammry glands.

The invention relates to a chiral CB1 (cannabinoid) receptor inhibitor which is showed as a general formula A1 and a general formula A2 and has optical asymetery performance, and slat or solvate which is physiologically acceptable, in particular relates to a diaryl-replaced pyrazole ramification CB1 receptor inhibitor which is showed as the general formula A and the general formula B, has optical asymetery performance and is hypotoxic, and the method also discloses a preparation method and an application used for preparing medicaments for detoxification, weight losing, diabetes mellitus treatment or cardiovascular disease preventing, and all application on medical science related with the CB1 receptor inhibitor.