The invention discloses a paste plaster for treating psoriasis. The paste plaster comprises the following raw materials in parts by weight: 20-28 parts of white alum, 21-27 parts of mirabilite, 20-28 parts of sulphur, 4-7 parts of borneol, 200-300 parts of vaseline and 80-120 parts of paraffin. The paste plaster for treating psoriasis is prepared according to the following steps: a, weighting theraw materials in parts by weight; b, grinding white alum, mirabilite, sulphur and borneol into fine powder, and screening by a 100-meshed screen for later use; and c, putting the mixture obtained in the step b in a mortar for uniform stirring, adding vaseline to blend uniformly, and then adding liquid paraffin to regulate uniformly. The components are mutually matched to dispel disease mainly, and relieve wind heat, relieve dampness and turbidity, activate collaterals, harmonize qi and blood to realize metabolism, clarify skin, smooth blood vessel and remove stasis to promote tissue regeneration. The paste plaster plays effects mainly by using local skin administration, and has no adverse effect when in use. The paste plaster can take effect after being used once to twice by a patient with mild symptom generally, skin can gradually become soft and thin, the symptom can be relieved within 10-25 days and skin is gradually improved to be normal; and patients with long course of disease and serious symptoms can be recovered in 1-2 months usually.