212 results about "Dermal irritation" patented technology

The invention belongs to the technical field of biological simulation, and discloses an anus cleaning effect evaluation method and system.The method comprises the steps that an execution assembly is controlled to wipe an anus anatomical structure with a to-be-detected sample according to a target wiping strategy, and a multi-mode sensing assembly is controlled to collect target parameters on the anus anatomical structure; obtaining target monitoring data; according to the residual dirt amount in the target monitoring data, a cleaning efficiency score is obtained through calculation, a target mechanical simulation model is called, according to the humidity permeation gradient value and the pressure value in the target monitoring data and the to-be-detected sample, a skin stimulation risk score is obtained through calculation, and the skin stimulation risk score and the cleaning efficiency score form a cleaning effect evaluation report. Simulation and prediction of the anus cleaning process are achieved, the simulation test effect and accuracy are greatly improved, and a cleaning effect evaluation report is given to illustrate the safety of the to-be-tested sample.

The invention relates to a natural plant composition for treating acne and application thereof. The composition comprises a scutellaria baicalensis extract, a fructus cnidii extract, a herba violae extract, a mangnolia officinalis extract, a Chinese herbaceous peony extract, a radix ophiopogonis extract, a silybum marianum extract and a gastrodia elata extract. The formula is designed according to the traditional Chinese medicine compatibility theory, and the composition formula has a synergistic effect and can effectively inhibit growth of propionibacterium acnes, reduce skin inflammation and generation of erythema and acne marks after acnes, promote fading of the acnes and skin repair and effectively treat the acnes. The composition is stable in formula quality, safe and free of skin irritation, provides a new thought for acne treatment and skin repair, and has a good market application prospect.

The invention relates to the field of cosmetics, in particular to a blue copper peptide composition with instantaneous cool feeling and infiltration promotion effects and a preparation method and application of the blue copper peptide composition. The composition comprises an active component copper-blue peptide and a cooling and permeation enhancing system formed by compounding at least two of menthane formylethylamine, menthone glyceryl ketal and methyl diisopropyl propionamide, and the active component can further comprise hexapeptide-11, a blue algae extract and a yeast fermentation product. The preparation method of the composition comprises three core steps of providing a water phase, adding the active ingredients and adding the cool and refreshing infiltration promoting system and other components. Through synergistic compounding of specific fresheners, on the premise that the use amount of each single component is remarkably reduced, efficient permeation promotion of the copper-blue peptide is achieved, the layered cool feeling experience which takes effect quickly and is lasting and mild is provided, the common skin irritation problem of a traditional permeation promoter or a high-concentration single freshener is avoided, and the effect is remarkable. And the transdermal patch has excellent transdermal efficiency, active matter stability and use comfort.

The invention relates to a medicine for promoting skin injury repair and healing and a preparation method thereof, and belongs to the technical field of biological medicines.The medicine is prepared from a radix astragali preparata extract, lipidosome encapsulated panax notoginseng total saponin-RGD peptide, a honeysuckle flower-maca extract, an asiaticoside-hydroxypropyl-beta-cyclodextrin inclusion compound and dipotassium glycyrrhizinate; the radix astragali preparata extract is a product obtained by moistening radix astragali with honey, baking, extracting with deionized water, and adsorbing and purifying with a Sephadex G-15 column; the honeysuckle-maca extract is a product obtained by mixing dry honeysuckle powder and dry maca root powder according to the mass ratio of (3-5): (1-1.7), performing enzymolysis through cellulase, then performing common enzymolysis through ficin protease and papain, and performing adsorption and purification through an HPD722 macroporous adsorption resin column. All the components are compatible according to a specific proportion, so that the allergy and skin irritation risks are reduced, skin injury healing is reasonably promoted, and melanin deposition is effectively inhibited.

The present invention relates to a composition for improving skin, which comprises beta-sitosterol and betulin and, in the case of the composition, reduces dermatoneuropathic stimulation-inducing factors, increases the expression of moisturizing-related factors, increases skin absorbance, improves skin penetration, inhibits mast cell activity, and improves skin quality. Thus, it has been confirmed that the composition has excellent skin-calming and skin-irritation-relieving effects, and thus can be usefully used in skin-improving cosmetics, pharmaceuticals, and the like.

The present application relates to the field of external ointment preparation, and provides a zinc gluconate ointment and a preparation method thereof.The ointment comprises, by mass fraction: 0.3-2.0 parts of zinc gluconate, 0.05-1.5 parts of L-histidine, 0.05-1.0 parts of polysaccharide, and the balance of purified water, wherein the polysaccharide is chitosan oligosaccharide or hyaluronic acid oligomer.The zinc gluconate, L-histidine and polysaccharide are dispersed to form hydrogel microdroplets under the condition of pH 5.0-6.0, and are further dispersed in the continuous phase of the oil phase.By establishing a complex system in a weak acid environment and using a double constraint structure of microdroplet dispersion and oil phase, the free Zn 2+ The initial release rate is reduced, skin irritation caused by the initial release of traditional preparations is avoided, and a high 24-hour cumulative release amount is maintained.The ointment exhibits excellent physical stability and particle size uniformity during storage, avoids oil-water layering and crystallization, and has both sustained release and good use feeling.

The invention provides lignan, and belongs to the technical field of medicines. According to the invention, a compound shown as a formula I and a compound shown as a formula II are extracted, separated and identified from schisandra chinensis oil for the first time, and the compound shown as the formula I and the compound shown as the formula II are superior to a positive drug group arbutin in the aspect of inhibiting generation of melanin of mouse skin melanoma cells (B16F10); an inflammatory factor release inhibition experiment research shows that the compound shown in the formula I and the compound shown in the formula II have relatively good activity in the aspect of inhibiting LPS-induced mouse mononuclear macrophage RAW264.7 from releasing IL-6 and TNF-alpha; in a skin irritation experiment, the schisandra chinensis non-saponifiable matter containing the compound shown in the formula I and the compound shown in the formula II is non-irritant to the skin of a white rabbit, and it is proved that the compound shown in the formula I and the compound shown in the formula II can be applied to preparation of whitening and anti-inflammatory products. Formula I; formula II.

The invention belongs to the technical field of cardio-cerebral oil preparation, and provides cardio-cerebral oil and a preparation method thereof. The invention aims to solve the technical problems that kapur is easy to volatilize and short in efficacy, and skin irritation is easily caused by high-concentration addition. The preparation method comprises the following steps: firstly, wrapping menthol in a molecular cavity of beta-cyclodextrin through a molecular inclusion technology to prepare a molecular capsule capable of effectively delaying volatilization and reducing irritation; secondly, preparing a bionic repair emulsion from various bionic lipids such as ceramide, cholesterol and fatty acid through an emulsification process, and taking the bionic repair emulsion as a core delivery carrier; meanwhile, components such as vanillyl derivatives are compounded to prepare a temperature-sensitive compound; the preparation method comprises the following steps: uniformly dispersing independent kapur, the molecular capsule and the temperature-sensitive compound into the bionic repair emulsion, and curing to obtain a finished product. Through molecular inclusion and the bionic repair emulsion, long-acting release of the effect of the kapur is realized, and the skin irritation of the product is reduced.

The invention provides a corn stigma extract-containing mask mud with repairing, anti-wrinkle and freckle-removing effects and a preparation method thereof, and relates to the technical field of cosmetics. The mask mud is prepared from the following raw materials: corn stigma extract, guava fruit extract, white willow bark extract, tamarix chinensis flower extract, sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium and auxiliary materials. The corn stigma extract is taken as a main raw material, and the three natural extracts, namely the guava fruit extract, the white willow bark extract and the tamarix chinensis flower extract, are compounded according to a specific proportion, so that multiple effects of resisting wrinkles, removing acnes, whitening, resisting allergy, repairing, removing freckles, tightening, moisturizing, soothing and the like are realized at the same time, and the effect of the corn stigma extract is remarkably improved; sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium is used as a surfactant, so that the lotion is milder and more moisturizing, no preservative is added, and damages such as skin irritation, allergy, red and swollen skin, cuticle damage and dry skin are reduced.

The invention relates to the technical field of health preserving articles, and discloses a wearable ornament based on a purple sand material and a preparation method thereof.The wearable ornament based on the purple sand material is obtained by soaking 20-30 parts by weight of porous purple sand bracelet in 40-60 parts by weight of a medicament for 20-25 min. The sand bracelet does not need a built-in medicine bag, keeps attractive appearance, does not need to be in direct contact with medicines when being worn, avoids skin irritation, and realizes perfect combination of a health preserving function and fashion ornaments; the purple sand material is environment-friendly and harmless and can be used for a long time, so that resource waste of disposable health-preserving products is reduced, and the traditional Chinese medicine formula adopts natural components and has small influence on the environment.

The utility model provides an elastic rotation structure of a tool bit group of a manual hair removal cutter, which relates to the technical field of hair removal cutters and comprises a handle bottom cover and a pressure fitting component, the pressure fitting component comprises a semi-arc block fixedly connected to the handle bottom cover, a sliding groove is formed in the semi-arc block, a rotating block is connected to the sliding groove in a sliding manner, and the rotating block is provided with a rotating shaft. A mounting seat is fixedly connected to the interior of the handle bottom cover, and a pressure elastic piece is fixedly connected to the top end of the mounting seat; the bottom end of the handle bottom cover is fixedly connected with a top rotating ring, and the interior of the top rotating ring is fixedly connected with an extension block; by means of the design, when the skin protrudes, the scalpel head can float upwards to prevent the skin from being stimulated by overlarge pressure; when the skin is sunken, the tool bit can extend downwards under the action of the elastic piece, contact pressure is kept, hair is prevented from remaining, the problems of skin irritation and hair remaining caused by uneven pressure when a traditional hair removing tool shaves are effectively solved, and the shaving effect and use experience of the manual hair removing tool are improved.

To provide a composition for a skin protectant having not only an effect of preventing dyeing of the skin but also an effect of suppressing skin irritation caused by skin irritant components, and having both a dyeing prevention effect and a skin irritation suppression effect.SOLUTION: A composition for a skin protectant, containing a smectite-based clay component that is at least one compound selected from the group consisting of smectite-based clay minerals and organically modified smectite-based clay minerals, and an oil-soluble component, further containing a nonionic dispersion aid having an HLB of 11.0 or less, wherein a content ratio of the smectite-based clay component is 0.01-60 mass% based on the total mass, the composition being applied to the skin to form, on the skin, a protective film for protecting the skin.SELECTED DRAWING: None

The article relating to this design is a nasogastric tube fixing device for guiding a nasogastric tube inserted into the nostril to the side of the patient's face and holding it in place. As shown in Reference Figure 3, which illustrates the state of use, the nasogastric tube is fitted into fixing grooves extending from the center of the main body in the left and right directions, and the ends of the main body are attached to the cheek area with fixing tape, so that the nasogastric tube is held in a state that makes it difficult to come off. Also, as shown in Reference Figures 2 and 3, which illustrate the state of use, elongated holes are formed at both ends of the main body, which also serve as retainers, and the device can also be used in a form in which a separate band is connected to these elongated holes and attached around the head. When using the band, it can be fixed without using fixing tape alone, and the device is designed to be easy to use with consideration for skin irritation, and it can also be used to hold the tube securely even when adhesion is difficult due to the shape of the area under the nose, such as when there is a beard or when there are no front teeth.

The application provides a non-contact pain monitoring mattress and system based on multi-modal physiological signal fusion, the mattress body comprises, from bottom to top, a bottom support layer, a signal shielding layer, a sensing core layer and a breathable skin-friendly layer, the system comprises the non-contact pain monitoring mattress, a low-noise charge amplifier, a fiber demodulator, an edge computing gateway and a cloud analysis center, the data after signal conditioning is transmitted to the edge computing gateway and uploaded to the cloud analysis center, and the cloud analysis center performs quantitative scoring through a tumor-specific pain model.The application has the advantages that no electrode or wearable device needs to be pasted, the skin irritation and psychological burden of traditional monitoring are completely eliminated, the patient compliance is improved, the limitation of subjective evaluation is broken through, an objective pain evaluation method is provided for patients in the late stage / aphasia, multi-modal signal fusion monitoring is used to effectively distinguish pain from ordinary emotional fluctuations, the degree of pain is fed back in real time, the doctor is assisted in dynamically adjusting the dose of analgesic drugs, and the risk of drug overdose and deficiency is reduced.

This invention relates to the field of pressure ulcer monitoring technology, specifically disclosing a pressure ulcer prevention monitoring system and monitor. The system includes a data recording module for recording material characteristic data of different types of mattresses and sheets. By recording the material characteristic data of different types of mattresses and sheets, and collecting data on sheet residues and chemical contaminants, the material characteristic data of different types of mattresses and sheets can reflect the friction risk between the patient and the mattress / sheet, while the data on sheet residues and chemical contaminants can reflect the soiling status of the sheet. By combining the above two sets of data, the pressure ulcer risk threshold can be assessed and dynamically adjusted based on diversified data such as the potential friction risk to the patient and the risk of skin irritation from sheet soiling, thereby improving the accuracy of subsequent patient pressure ulcer risk analysis results.

The invention relates to the technical field of medical coupling agents, and discloses a medical sterile ultrasonic coupling agent which comprises the following components: carbomer, a humectant, a quaternary ammonium salt disinfectant, a preservative, a pH regulator and purified water. A preparation method of the medical sterile ultrasonic coupling agent comprises the following steps: step 1, dispersing the carbomer in part of purified water, stirring until the carbomer is completely swelled, adding the preservative and the pH regulator, and continuously stirring for 20 minutes; step 2, dissolving a quaternary ammonium salt disinfectant and a humectant in the residual purified water, uniformly mixing, adding into the gel in the step 1, and vacuumizing and stirring for 10 minutes; and step 3, performing irradiation sterilization after filling to obtain a finished product. Compared with the prior art, the invention has the advantages that: the quaternary ammonium salt is used for replacing triclosan, so that skin irritation and environmental pollution are avoided, and the safety is high. A solubilizer is not needed, and the production process is simplified. According to the invention, the compatibility problem of quaternary ammonium salt and carbomer is solved through a special process, and the stability and viscosity of the product are ensured.

The invention provides a medical instrument skin stimulation test data processing method based on an artificial skin model, and relates to the technical field of skin stimulation tests. Collecting the original OD value of each pore in the 96-pore plate under the wavelength of 570nm; calculating the survival rate and the standard deviation of the positive control group and the test sample group; verifying the data validity of the negative control group and the positive control group; and performing skin irritation judgment according to the average survival rate of the test sample group to obtain a skin irritation type. According to the method, the in-vitro skin model based on HTWSkinRHE is established, strict standardized culture conditions and grouping design are adopted, the batch-to-batch consistency and data comparability of the experimental model are remarkably improved, and the model can better meet more medical instrument requirements; the cell activity is detected by simulating a complete skin layered structure and combining an MTT method, and the judgment threshold value is highly matched with the in-vivo stimulation response.

The invention relates to the technical field of cotton fabric manufacturing, in particular to a charge transfer and transition bacteriostatic pure cotton non-woven fabric and a manufacturing method thereof.The manufacturing method includes the steps that raw cotton is degreased, opened and carded, base cloth is manufactured through a spunlace method, and the pretreated pure cotton non-woven fabric is obtained after drying and impurity removing; the preparation method comprises the following steps: soaking cotton fibers into a charge transfer transition reagent containing alizarin and waterborne polyurethane, accurately loading through a four-roller unit, and curing through 254nm-365nm ultraviolet light, so that the reagent and the cotton fibers form covalent bonds to realize charge transfer transition. An ultrathin polymer film layer is formed on the cloth cover of the product, million-level electron-hole pairs are contained, the initial bacteriostasis rate exceeds 99%, and a good bacteriostasis effect is still kept after the product is washed with water for 150 times. The antibacterial non-woven fabric adopts a natural antibacterial agent, is free of skin irritation and toxic residues, is environment-friendly in production process, has skin friendliness and mechanical strength, is suitable for medical and hygienic products such as surgical gown and medical dressing, and solves the problems of poor washability, potential safety hazards and the like of the traditional antibacterial non-woven fabric.

The invention relates to the technical field of cosmetics, in particular to a preservative-free cosmetic composition for barrier repair as well as a preparation method and application of the preservative-free cosmetic composition. The invention relates to a preservative-free cosmetic composition for barrier repair, which comprises the following components in percentage by weight: 4.0-6.0% of 1, 2-pentanediol; 0.5% to 1.0% of 1, 2-hexanediol; 0.1% to 0.5% of cerayl; 0.5%-1.0% of phytosterol; 4.0%-6.0% of stearic acid; 4.0%-7.0% of hydrogenated lecithin; 0 to 0.3 percent of caryophylline; 0-0.2% of a eucommia ulmoides bark extract; and the balance of water. The composition of 1, 2-pentanediol and 1, 2-hexanediol is adopted to replace a traditional chemical preservative, and on the premise that the preservative effect is achieved, the possibility of causing skin irritation and allergy risks is reduced; ceramide and phytosterol can participate in construction of a skin barrier and supplement and repair a lipid structure of the skin barrier; stearic acid and hydrogenated lecithin form a stable emulsification basis, so that the two long-term contradictory requirements of no chemical preservative stimulation and effective barrier repair are met, and the unification of product safety and efficacy is realized.

The invention belongs to the technical field of biological medicine, and particularly relates to a formula and application of a microcrystal patch containing polysulfonic acid mucopolysaccharide. The microcrystal patch disclosed by the invention is prepared from the following components in percentage by mass: 96 to 97 percent of purified water, 0.6 percent of polyvinyl alcohol, 1 to 2 percent of sodium hyaluronate with the molecular weight of 50,000 to 10,000, 0.6 to 1 percent of sodium hyaluronate with the molecular weight of 400,000 to 800,000 and 1 to 2 percent of polysulfonic acid mucopolysaccharide. The result of the embodiment shows that the patch with weak mechanical property is adaptive to the part with weak cuticle and sensitive skin, and the patch with strong mechanical property is adaptive to the part with thick cuticle. Through the physical permeation promotion effect of microcrystals, polysulfonic acid mucopolysaccharide can be efficiently carried to penetrate through a skin barrier to directly reach a target part, and the medicine utilization rate is remarkably increased; the formula is simple in components, the skin irritation risk is reduced from the source, and the production cost is reduced.

The invention provides a mild refreshing borneol essential oil compound as well as a preparation method and application thereof. The borneol essential oil compound is prepared from the following components in parts by weight: 1 to 50 parts of borneol, 0.1 to 50 parts of menthol, 1 to 10 parts of natural camphor, 0.1 to 0.5 part of herba dendrobii essential oil, 35 to 70 parts of carrier oil, 0.2 to 1 part of vitamin E, 1 to 3 parts of eudesmol, 0.2 to 1 part of limonene and 0.5 to 5 parts of cinnamomum camphora essential oil clathrate compound. The borneol essential oil compound prepared by the invention has the advantages of better stability, high essential oil retention rate, freshness and durability, mild components without skin irritation, and refreshing effect, and can be applied to preparation of products such as snorting essential oil, roll-on essential oil or vehicle-mounted fragrance and the like.

The present invention relates to skin adhesive formulations. The skin adhesive formulations of the present invention may be useful in wound-closing applications and other medical applications. Ideally the skin adhesive formulations of the present invention exhibit higher viscosity than known skin adhesive formulations. Ideally the skin adhesive formulations of the present invention cause fewer allergic reactions and skin irritation issues in patients relative to known skin adhesives. Ideally the skin adhesive formulations are UV curable in the visible range of 400-500nm rather than moisture cure.

The present application relates to the technical field of external use patch, disclose a kind of neck shoulder waist leg pain health care patch and its preparation method, the health care patch includes backing layer, ointment layer and anti-adhesion release layer;Ointment layer raw material includes: traditional Chinese medicine extract flow leaching paste, L- (+) -tartaric acid, PVP K30, PEG-400, ternary eutectic solvent, polyacrylate pressure sensitive adhesive matrix and ultrafine medicinal powder.Preparation, after flow leaching paste, tartaric acid etc. are mixed, gel precursor is formed by vacuum dewatering and dealcoholization, swelling is added again with eutectic solvent, and then mixed with pressure sensitive adhesive matrix and medicinal powder high shear, finally coating solidification.The present application constructs physical crosslinking gel network in colloid interior and promotes effective component acid-base salt formation, effectively avoids polar component crystallization precipitation, reduces the skin irritation caused by drug burst release, simultaneously improves the cohesion of ointment, realizes long-acting smooth drug release.

The present invention relates to a composition for alleviating skin irritation caused by vitamin C, and an information providing method for selecting a custom-made substance for alleviating irritation caused by vitamin C, comprising a step of confirming a base of a polymorphic site of a gene polymorphic marker which is significant in relation to the degree of irritation caused by vitamin C. The invention also relates to a composition for alleviating skin irritation caused by vitamin C and an information providing method for selecting the custom-made substance for alleviating irritation caused by vitamin C. Furthermore, the present invention relates to: a composition for diagnosing whether or not a skin type in which skin irritation caused by vitamin C is likely to occur, the composition comprising a probe capable of detecting a gene polymorphism marker having significance in association with skin irritation caused by vitamin C or a preparation capable of amplifying the gene polymorphism marker; a kit or a microarray comprising the composition; and a method for providing information on the type of skin, which is susceptible to skin irritation caused by vitamin C, using the gene polymorphism marker or the combination of markers.

The invention discloses a millimeter wave radar-based pressure sore prevention early warning method and system, and the method comprises the steps: collecting a radar echo signal of a bed body region through a millimeter wave radar, and generating point cloud data containing distance and speed information; whether the patient is in bed is judged; when it is judged that the patient is in bed, processing the point cloud data to track the trunk and limbs of the patient; based on the tracking result, large-amplitude body movement and small-amplitude body movement of the patient are recognized through a multi-feature fusion body movement algorithm, and the effectiveness of body position change is judged; and according to the body movement identification and validity judgment result, performing pressure sore risk assessment, and sending out early warning information when the risk exists. According to the method, the defects of a traditional contact sensor and artificial nursing are overcome. Complete non-contact monitoring is achieved, direct contact with the body of a patient is avoided, discomfort, oppression and skin stimulation are eliminated, the risk of cross infection is reduced, information transmission timeliness and response speed are improved, and support is provided for data-driven decision making and medical research.

An ostomy pouch can include one or more sensors for measuring one or more indicators. An ostomy wafer can also include one or more sensors for measuring one or more indicators. For example, the sensors can be temperature sensors and / or capacitive sensors, and the indicators can include pouch fill, leakage, skin irritation, and equality of ostomy output.

The invention provides a biological medicine containing borneol liquid oil for skin diseases and a preparation method, and relates to the technical field of biological medicine manufacturing. The main points of the technical scheme are as follows: the anti-inflammatory and antibacterial borneol skin care lotion comprises the following components in percentage by weight: 5-25% of borneol liquid oil, 2.5-7.5% of an anti-inflammatory and antibacterial double-effect plant extract, 1.5-5.5% of a skin micro-ecological regulation type active substance, 1-3% of a skin barrier repairing and moisturizing type active substance, 0.5-3% of a skin antioxidant protection type active substance, 0.5-2% of a cooling, soothing, anti-inflammatory and analgesic double-effect substance and 60-75% of a special solvent for the fields of medicine and skin care. According to the skin disease biological medicine containing the borneol liquid oil and the preparation method provided by the invention, skin irritation and drug resistance risks are reduced, the bioavailability is improved, and meanwhile, the skin disease biological medicine also has the advantages of promoting skin micro-ecological regulation, resisting inflammation and bacteria synergism and realizing multi-target treatment of complex skin diseases.

This application discloses a razor head assembly and a razor having the same. The razor head assembly includes a base, a razor head holder, and a floating mechanism. The base has an axis; the razor head holder is equipped with the razor assembly; the floating mechanism connects the base and the razor head holder, and allows the razor head holder to deflect relative to the axis under the action of an external force, and allows the razor head holder to return to its original position after the external force is removed. This application, through the floating mechanism, allows the razor head holder to deflect relative to the axis of the base during shaving, thereby maintaining a good fit between the razor assembly and the user's face; it also helps to tighten the facial skin, allowing the hair roots to be better exposed on the skin surface, improving shaving cleanliness, while also enhancing shaving comfort and experience, reducing pressure on the skin during shaving, and minimizing skin irritation; furthermore, the razor head holder can return to its initial position after the external force is removed for subsequent use.

Embodiments of the present disclosure relates to a drain cap for an ostomy bag. The drain cap may be a rectangular pocket shaped structure configured to fit over drainage end of an ostomy bag and prevent accidental openings and provide enhanced user comfort. The pocket may be formed from a fabric having two layers of polyester-spandex and a layer of neoprene sandwiched between the two layers of polyester-spandex. The fabric may provide sufficient elasticity to secure the pocket in place during use. Further, the fabric may provide sufficient thickness to provide cushioning against the drainage end of the ostomy bag preventing skin irritation caused by contact with sharp and rigid edges. The drain cap may slip on easily, stays securely in place due to its bi-directional stretch, and protects the skin from irritation caused by sharp edges.