67 results about "IRRITATION SKIN" patented technology

The invention provides a recombinant keratin polypeptide as well as a preparation method and application thereof, and relates to the technical field of genetic engineering. The amino acid sequence of the recombinant keratin polypeptide is as shown in any one of SEQ ID No. 1, SEQ ID No. 4, SEQ ID No. 7 and SEQ ID No. 10. The recombinant keratin polypeptide has a good soothing effect and the effects of stimulating skin angiogenesis and improving local blood circulation, and can be widely applied to the industries of medicines, cosmetics, skin care products and the like.

Provided are methods and composition for treating skin barrier functions and associated disorders. Formulated compositions may be applied on human skin to maintain a desired skin surface pH over an extended period of time without irritating the skin. Maintaining the desired surface pH aids in treatment of eczema, in addition to other skin conditions.

The present invention provides an anti-aging, whitening, freckle-removing, moisturizing skin care water and a preparation process thereof. A preparation process for an anti-aging, whitening, freckle-removing, moisturizing skin care water comprises the following steps: supercritical CO2 extraction of oat-yarrow extract; ultrasonic-enzymatic hydrolysis-assisted reflux extraction and concentration; adding oxidized resveratrol, salidroside and ellagic acid; adding purified water to dissolve and adding sodium alginate and glycerol; adding p-anisic acid and aromatic alcohol and homogenizing and mixing. The present invention is a skin care water prepared by first extracting extracts of bletilla striata, wormwood leaf, peony bark, oat and yarrow, and then adding oxidized resveratrol, salidroside, ellagic acid, sodium alginate, glycerol, p-anisic acid and aromatic alcohol. The skin care water not only has the effects of anti-aging, whitening, freckle removal and moisturizing, but also because its raw materials are all natural plant ingredients and no chemical agents are added, therefore, it will not irritate the skin and has no side effects, and can be used for a long time.

The present invention relates to compositions or formulations or systems comprising said compositions or formulations for aftercare of a recently-created tattoo on a skin, said compositions or formulations or systems comprising a tattoo aftercare sealant gel, said tattoo aftercare sealant gel comprising: gel-forming-and-bonding components; and natural ingredients for healing to alleviate the risk of wounding or scarring or infection or drying of the skin or irritating the skin, and to keep the tattoo from fading or drying out. Further, the present invention also discloses methods of production of the compositions or formulations, or systems for aftercare of a recently-created tattoo on a skin as disclosed herein, and it creates a tattoo aftercare sealant gel of the present invention.

The invention relates to the technical field of traditional Chinese medicine external preparations, in particular to an industrialized preparation method of an emplastrum composition capable of improving safety. The preparation method comprises the following steps: partially dissolving rubber by using gasoline A, then adding rosin, and stirring for dissolving; adding activated zinc oxide, mixing, adding lanolin, vaseline, musk wind-dispelling and pain-relieving liquid extract, belladonna liquid extract, rutin extract, menthol, borneol, camphor, methyl salicylate and a gasoline B part, and performing pH regulation to obtain musk wind-dispelling and pain-relieving paste mucilage; the activated zinc oxide is obtained by the following steps: mixing zinc oxide and liquid paraffin, and standing for 2-4 hours in an environment of 120-140 DEG C, so as to obtain the activated zinc oxide. According to the technical scheme, on the basis of keeping the treatment effect of the original medicinal components, the technical problem that the musk wind-dispelling and pain-relieving ointment contains viscous matrix components such as rosin and rubber, so that the skin is easily stimulated, and adverse reactions such as skin erythema are generated is solved, and the musk wind-dispelling and pain-relieving ointment has good market prospects and social benefits.

The utility model provides an elastic rotation structure of a tool bit group of a manual hair removal cutter, which relates to the technical field of hair removal cutters and comprises a handle bottom cover and a pressure fitting component, the pressure fitting component comprises a semi-arc block fixedly connected to the handle bottom cover, a sliding groove is formed in the semi-arc block, a rotating block is connected to the sliding groove in a sliding manner, and the rotating block is provided with a rotating shaft. A mounting seat is fixedly connected to the interior of the handle bottom cover, and a pressure elastic piece is fixedly connected to the top end of the mounting seat; the bottom end of the handle bottom cover is fixedly connected with a top rotating ring, and the interior of the top rotating ring is fixedly connected with an extension block; by means of the design, when the skin protrudes, the scalpel head can float upwards to prevent the skin from being stimulated by overlarge pressure; when the skin is sunken, the tool bit can extend downwards under the action of the elastic piece, contact pressure is kept, hair is prevented from remaining, the problems of skin irritation and hair remaining caused by uneven pressure when a traditional hair removing tool shaves are effectively solved, and the shaving effect and use experience of the manual hair removing tool are improved.

The application relates to the field of biomaterials, in particular to a preparation method of injectable acellular matrix powder and application thereof. The preparation method of the injectable acellular matrix powder is obtained through two discontinuous crosslinking steps of once crosslinking and twice crosslinking after crushing of acellular basement membrane. The obtained injectable acellular matrix powder with a unique crosslinking network structure is adapted to the natural skin pH value, greatly enhances the biocompatibility, simultaneously inhibits excessive inflammatory reaction and accelerates tissue healing through the induction of M2 polarized macrophage activation, effectively relieves the local tissue compression risk possibly caused by high cohesive force due to amino acid modification and introduction of a double crosslinking agent, realizes dynamic balance of mechanical stability and physiological friendliness, continuously stimulates the generation of skin collagen by using controllable moderate inflammatory reaction, and promotes gradual reconstruction and improvement of tissues.

The invention relates to the field of cosmetics. The invention relates more particularly to a method for the cosmetic care of sensitive skin, characterized in that it comprises the application to said sensitive skin of a composition comprising flocculosine as active agent, to obtain a soothing effect by stimulating the production of beta-endorphin and / or the expression of the CB2 receptor by the cells of said sensitive skin, said composition being optionally incorporated into a cosmetically acceptable excipient. The invention also relates to the non-therapeutic use of flocculosine to stimulate the production of beta-endorphin and / or the expression of the CB2 receptor by skin cells. Figure to be published with the abstract: Figure 2

The present invention relates to a two-color cleansing mud mask combination and a preparation method thereof. The two-color cleansing mud mask combination includes component A and component B; both component A and component B include a humectant, an emollient, an emulsifier, a skin conditioner, a filler, and water; the filler of component A includes kaolin, pearl powder, and bentonite; the filler of component B includes kaolin, carbon powder, and bentonite. The cleansing mud mask of the present invention adopts a two-component combination, with two mud groups having different effects cooperating and synergizing, combining cleansing and prevention, and multiple components being compounded. While not irritating the skin, it can better promote the metabolism of the stratum corneum. It can not only deeply clean the skin, better adsorb pore dirt, but also precisely adjust the state of each area of the skin.

The present invention generally relates to the field of cosmetics. More particularly, the invention relates to a cosmetic skincare composition comprising a seed extract of the plant Annona cherimola. The invention is based on the finding that such seed extract has several favourable effects on skin. Amongst others, a seed extract of Annona cherimola exerts calming, soothing, moisturizing and anti-itching effect. In another aspect, the invention therefore provides a cosmetic method of improving skin appearance or reducing skin dryness in a subject, comprising administering a skin care composition of the present invention. In yet another aspect, the invention provides a cosmetic method of soothing or calming irritated skin in a subject, comprising administering a skin care composition of the present invention. The invention also relates to the use of a seed extract of Annona cherimola for skin care, and in particular for soothing or calming irritated skin, or improving skin appearance or reducing skin dryness and itching.

The present invention relates to a skin-stimulating patch capable of autonomously contracting, and more particularly, to a skin-stimulating patch comprising a contractile material and a trigger material. According to one embodiment of the present invention, it is possible to provide a patch for skin stimulation, which is a patch capable of stimulating skin, and which comprises: a contractile material that can contract under a preset condition; and the triggering material is used for applying preset energy to the contractile material so that the condition can be met.

The present invention relates to a cosmetic material composition comprising menthol-based and non-menthol-based cooling agents as cooling ingredients, and specifically, to a transparent cosmetic material composition in which a high content of menthol-based and non-menthol-based cooling agents is stabilized through the addition of a specific solubilizer, and which thus exhibits an excellent cooling effect without irritating the skin.

The utility model provides an aromatherapy application type automatic red and blue electro-microneedle instrument, which relates to the technical field of micro-needle instruments and comprises an electro-microneedle instrument body, a telescopic mechanism is arranged at the top of the inner side of the electro-microneedle instrument body, and a chassis is arranged at the bottom of the telescopic mechanism. According to the electric microneedle instrument, under the cooperation of the telescopic mechanism, regeneration and repair of stimulated skin can be facilitated through the focal dot matrix injury effect, then radio-frequency current is transmitted to the microneedles through the control of the electric microneedle instrument body, the skin absorption energy can be improved, pores can be shrunk, and through the arrangement of the red and blue light lamp beads, the skin can be effectively absorbed. Red and blue light irradiation can accelerate bacterial death through released singlet oxygen so as to achieve the effects of sterilization and inflammation diminishing, then a semi-closed liquid storage container is arranged, essential oil is stored in the semi-closed liquid storage container, small molecules in the essential oil permeate into skin, blood and particle molecules in an air fumigation mode so as to stimulate the cerebral cortex, and therefore the effects of sterilization and inflammation diminishing are achieved. The effect of relieving pain is achieved.

This item is an attachment for face washing and lift care of a hair washing device, and the protrusions vibrate to stimulate the skin and remove dirt.

The invention relates to the technical field of alginic acid and derivatives thereof, and particularly discloses an antibacterial fabric, a preparation method and application. The anti-bacterial fabric comprises a one-way moisture guiding layer and an anti-bacterial layer, the functional core layer is a honeycomb-shaped porous fiber net and comprises a compound formed by alginic acid and derivatives thereof and organosilane quaternary ammonium salt which are connected through an alkylation reaction, and waterborne polyurethane; porous starch microspheres loaded with an auxiliary antibacterial agent are packaged in pores of the functional core layer. The preparation method comprises the steps of preparation of porous starch microspheres, preparation of a spinning solution, electrostatic spinning, curing, hot-pressing compounding and the like. According to the antibacterial fabric disclosed by the invention, through synergism of the alkylated compound, microsphere slow release and a porous structure, the antibacterial ability is greater than or equal to 97% after 50 times of water washing; oWTC is larger than or equal to 0.9, skin irritation is 0 point, the problems that a traditional fabric is short in antibacterial time, poor in moisture conductivity and prone to skin irritation are solved, and the fabric can be used for sportswear, underwear and the like.

The invention belongs to the technical field of patting therapy bars, and particularly relates to a patting therapy bar which comprises a bar body, a handle head is arranged at one end of the bar body, a groove is formed in one side of the handle head, a magnet is arranged in the groove, a limiting head is arranged at the other end of the bar body, and the handle head, the bar body and the limiting head are all made of nylon plastic materials. The rod body is made of the nylon plastic material, the beating weight is increased through the magnet, under the same force, the skin can be effectively stimulated, qi and blood circulation can be promoted, and the eruption effect can be achieved under the painless or slight-pain condition.

The invention relates to the technical field of cosmetics, and discloses a concealer composition, a preparation method thereof and a concealer pen. The concealer composition comprises the following raw material components: an emollient I, an emollient II, a plasticizer, a film-forming agent I, a film-forming agent II, a thickening agent, an antioxidant I, an antioxidant II, a dispersing agent, a preservative and a coloring agent, the emollient I is a mixture of polysiloxane and vegetable fat; the emollient II is a mixture of at least two kinds of polysiloxane; the plasticizer is synthetic wax; the film-forming agent I is organic silicate ester; and the film-forming agent II is a mixture of polysiloxane and a silicone-organic alkyl copolymer. The preparation method is simple, efficient and controllable in condition, the prepared concealer composition has high covering power, durability, stability and good skin feeling, and the problems that an existing concealer product is prone to makeup removal, powder blocking or skin irritation are solved.

A light energy treatment method for target areas of skin or mucosa infected by herpes virus or other viral infections includes providing a plurality of light sources which generate light energy having a wavelength between 620 nm to 1500 nm; generating a series of light energy from the light sources in continuous wave mode or in pulsed mode with a pulse rate of 1 to 10000 Hz; applying the light energy in continuous wave mode or in pulsed mode to target areas of the skin or mucosa for 1 to 2000 seconds to achieve a power density between 20-500 mw / cm2; and stimulating cell mitochondria of the target areas of the skin or mucosa to increase cellular energy in the target areas of the skin or mucosa for cellular repair.

This product is a device that electrically generates low frequency waves, vibrations, heat, cooling, and ions, and stimulates the surface of the skin and its surroundings, enhancing the skin beautifying effect and promoting the penetration of cosmetics. It is used by touching the three metal heads shown in the upper left corner of the front view with the lid removed to the skin.

Provided are methods and composition for treating skin barrier functions and associated disorders. Formulated compositions may be applied on human skin to maintain a desired skin surface pH over an extended period of time without irritating the skin. Maintaining the desired surface pH aids in treatment of eczema, in addition to other skin conditions.

The present invention relates to a composition comprising a combination of at least two cosmetic active agents, said combination of active agents preventing or reducing the loss of proteostasis, preventing or reducing micro-inflammatory processes, preventing cellular senescence, and preventing or reducing mitochondrial dysfunction and / or stimulating mitochondrial energy metabolism in skin cells The invention also relates to the cosmetic use of such a composition for increasing the longevity of skin cells and skin tissues, for preventing or reducing the loss of proteostasis, preventing or reducing micro-inflammatory processes, preventing cellular senescence and preventing or reducing mitochondrial dysfunction and / or stimulating mitochondrial energy metabolism, in skin cells. Finally, the invention relates to a nontherapeutic cosmetic process for caring for keratin materials comprising the topical application of such a composition.

The invention belongs to the technical field of colored drawing pigments, and particularly relates to a pigment for human body colored drawing and a preparation method thereof.The pigment comprises the following components in parts by mass: a base emulsion component including 40-50 parts of nano silicon PU modified acrylic resin emulsion, 20-30 parts of poly carbon waterborne polyurethane resin PUD emulsion and 3-5 parts of polyvinylpyrrolidone; 25 to 55 parts of a wax component; 15 to 45 parts of an oil component; 7-18 parts of a pigment component; 3-5 parts of vitamin E; 4-6 parts of mint; 5-7 parts of wool fat; 3-5 parts of aloe juice; the oil component, the wax component and the resin system are compounded, a layer of continuous film with certain strength can be formed on the skin on the premise that the skin is not irritated, the dried paint film can be tightly attached to the skin texture to improve the painting effect, it can be guaranteed that the paint film is not prone to cracking and falling off at the joint movement position, and the painting effect is improved. Meanwhile, the oil wax component, the vitamin E, the aloe juice and the like added into the pigment can improve the gloss effect of a film layer and achieve the skin care effect at the same time, and colored drawing can be slightly torn off only through hot compress.

This invention belongs to the field of cosmetic technology, specifically disclosing a multi-protein synergistic firming, anti-wrinkle, soothing, and repairing cosmetic composition, its preparation method, and its application. The cosmetic composition, by weight, is prepared from the following raw materials: 0.001-0.1 parts of Ma Yinglong Babao raw powder, 0.01-5 parts of oat firming protein, 0.01-1 part of silk protein, 0.001-0.1 parts of recombinant collagen, 0.001-0.1 parts of recombinant fibronectin, and 0.0001-0.1 parts of recombinant mussel protein. This invention utilizes the precise combination of oat firming protein, silk protein, recombinant collagen, recombinant fibronectin, recombinant mussel protein, and Ma Yinglong Babao raw powder to construct a four-in-one efficacy system of "firming-anti-wrinkle-soothing-repairing," achieving synergistic effects among the proteins. This solves the problems of existing products having single efficacy, poor synergy, and easy skin irritation, providing a highly effective and gentle comprehensive care solution for aging skin, sensitive skin, and skin with damaged skin barriers.

The present invention provides a composition for treating mosquito bites, which is made of the following raw materials: patchouli, atractylodes, cinnamon, schizonepeta, elsholtzia, wormwood, clove, prickly ash, mint and natural borneol. The composition for treating mosquito bites of the present invention has a good therapeutic effect on mosquito bites, can relieve itching and pain, reduce inflammation, reduce swelling, prevent infection, prevent the spread of diseases, and has a mild formula and does not irritate the skin. Moreover, the composition for treating mosquito bites of the present invention is a traditional Chinese medicine component, and compared with chemical drugs, it not only has a good effect of treating mosquito bites, but also avoids the side effects produced by chemical drugs.

The invention belongs to the technical field of cosmetics, and particularly relates to an anti-aging repairing composition and a cosmetic. The anti-aging repairing composition comprises needle-like silica and a nucleic acid tetrahedron solution. According to the composition and the cosmetic, controlled skin injury is formed through the needle-like silica, skin pore blockage is relieved, natural stripping of aged cuticle is accelerated, microcirculation of skin cells below the cuticle is activated, the overall metabolic condition of epidermis is improved, a natural skin repairing mechanism is stimulated, and under the synergistic effect of tFNA, the skin can be effectively repaired. Synthesis of important construction substances such as collagen, elastin and hyaluronic acid is promoted, the skin barrier function is repaired, and the skin health state is improved. Therefore, various skin defects such as skin photoaging, roughness, relaxation, wrinkles, dryness, hyperpigmentation, sensitivity and angiotelectasis are remarkably improved.

This invention proposes a Bifida ferment lysate, its preparation method, and its application, belonging to the field of cosmetic technology. The first fermentation product is obtained by enzymatic fermentation of Ganoderma lucidum, Poria cocos, Nostoc commune, oats, lactoferrin, and ginseng. Konjac gum hydrolysate and collagen and glycosaminoglycans extracted from tilapia skin are added, and fermentation continues to obtain a second fermentation product. Modified lysozyme is added for enzymatic hydrolysis, followed by centrifugation. The supernatant is collected, and copper and calcium salts are added and stirred to obtain a Cu-Ca chelated fermentation lysate. The product is then encapsulated to obtain the Bifida ferment lysate, which has excellent whitening, moisturizing, antibacterial, soothing, skin-repairing, and pH-regulating effects on the skin. It is safe, non-toxic, non-irritating to the skin, highly absorbable by the skin, and has a long shelf life, showing broad application prospects.

The invention is applicable to the field of biotechnology and skin care, and provides a preparation method of stem cell exosome mask and essence, high-purity exosome is extracted and combined with a biocompatible high polymer material and active ingredients, and an external mask and essence combination with a repairing effect is prepared. The method specifically comprises the following steps: preparing exosomes, purifying the exosomes, detecting the quality of the exosomes, constructing an exosome regeneration mechanism and dosage model, performing efficacy and formula design according to the model, developing a production process, controlling the quality of exosome preparation, and designing a packaging device of a product. The invention aims to break through the technical bottleneck of a traditional skin care product, provides an efficient exosome mask and essence combination which is stable in structure, synergetic in function, convenient to use and suitable for sensitive skin and post-medical and art care, and promotes the functional skin care product to develop towards the direction of precise repair and multifunctional synergy. The urgent demand of the market on high-activity and low-irritation skin care products is met.

The invention discloses a traditional Chinese medicine composition for treating beriberi, eczema and heat miliaria, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from ginger powder, wormwood, green prickleyash, artemisia apiacea, sambucus chinensis, senecio scandens, black pepper and flos caryophylli. A broad-spectrum antifungal network is formed by the green prickleyash and the flos caryophylli, and dual inhibition is achieved on beriberi pathogenic bacteria and eczema secondary infection bacteria; artemisia argyi and artemisia apiacea are in cold-warm compatibility to regulate damp-heat toxin bidirectionally, the former warms channels, dispels cold and improves microcirculation, the latter clears heat, cools blood and inhibits inflammatory factors, sambucus chinensis can accelerate healing of an erosive surface, black pepper can expand blood capillaries to promote medicine permeation, and meanwhile, the warming, dredging and cold dispelling effects of ginger powder are improved. According to the invention, wormwood and green prickleyash are used as monarch drugs to mainly attack core pathogenesis, ginger powder and black pepper are used as ministerial drugs to enhance transdermal absorption, and cold-warm balance prevents pure heat-clearing drugs from aggravating dampness stagnation or pure warm drugs from stimulating skin.

The invention provides a boa oil-containing traditional Chinese medicine composition for treating tinea of hands and feet and skin infection and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw materials: boa oil extract, pteris multifida, vespertilionum vespertilionum, adenosma indianum, carambola, ficus himalayana and radix clematidis. The traditional Chinese medicine composition disclosed by the invention is compatible, has the effects of clearing heat and drying dampness, purging fire for removing toxin, dispelling wind and arresting itching, has a remarkable fungus inhibition effect, is high in curative effect and short in treatment course, realizes simultaneous treatment of principal and subordinate symptoms, fundamentally eliminates bacterial infection, helps a patient to thoroughly get rid of the trouble of skin tinea manus and pedis tinea, and recovers a normal living state. Meanwhile, the traditional Chinese medicine composition has no side effect, does not irritate the skin and is high in safety.

The present disclosure relates to an antimicrobial foam hand soap comprising an antimicrobial active, an alkyl polyglucoside surfactant, a cationic biguanide surfactant, a nonionic and / or cationic surfactant, and a colorant to provide a foam stable ready to use (RTU) liquid having a skin-non-irritating pH of between about 2 and about 10. The composition produces a fine, stable foam of the desired color as a time-lapse indicator while also providing improved cleaning, foaming and antibacterial properties.