29results about How to "Stable efficacy" patented technology

The invention is applicable to the technical field of drug-loaded polymer medical preparations, and provides a flurbiprofen-based analgesic spray and a preparation method thereof, the flurbiprofen-based analgesic spray comprises the following components by weight: 0.5%-10% of flurbiprofen, 5%-15% of a cosolvent, 0.5%-15% of a humectant, 0.01%-1.5% of a preservative, 0.1%-5% of a penetration enhancer, and the balance of purified water; preferably, the analgesic spray comprises the following components in percentage by weight: 1.0%-8.0% of flurbiprofen, 8%-12% of a cosolvent, 5%-10% of a humectant, 0.01%-1.0% of a preservative, 0.5%-3% of a penetration enhancer and the balance of purified water. According to the scheme, the high-dose flurbiprofen spray can release more quickly than a sustained-release patch within the same time, the analgesic spray is more stable in efficacy and more quick in effect, and the analgesic spray is simple in preparation process, moderate in dosage of raw materials and auxiliary materials, stable in efficacy and capable of meeting clinical requirements.

The invention provides traditional Chinese medicine fermented disaccharide encapsulated nano anti-dandruff, hair-growing and oil-controlling shampoo and a preparation method, and relates to the field of daily chemical products, and the shampoo comprises the following components: a compound fermentation product, lactobacillus crispatus, lactobacillus plantarum, a disaccharide activity protection system, a basic component and a nano oil-controlling component; the compound leavening is prepared from cacumen biotae, radix polygoni multiflori, radix ginseng, fructus cnidii and orchid; the disaccharide activity protection system comprises maltotetraose and trehalose; the disaccharide activity protection system wraps a fermented material formed by fermenting the compound fermentation product, the lactobacillus crispatus and the lactobacillus plantarum to form a disaccharide glassy state layer; the nano oil control component is prepared from calamine powder and chitosan-sodium alginate; the basic component is prepared from tea bran, radix sophorae flavescentis, herba ecliptae, radix notoginseng, fructus ligustri lucidi, tea saponin microcapsules and tremella polysaccharide. According to the invention, through fermentation conversion of the orchid, disaccharide glassy state protection and slow release of the nano calamine, activity enhancement, stable retention and accurate release are realized, and the effects of removing dandruff, relieving itching, controlling oil and growing hair are achieved.

The invention discloses a natto peptide sea cucumber polysaccharide liposome for synergistically improving cardiovascular health and a preparation method and application thereof, belongs to the field of active peptide delivery systems, and aims to solve the stability problem of natto oligopeptide in gastrointestinal digestive tracts. The phytosterol and the vitamin E are filled between phospholipid double layers of the liposome to support a gap between the phospholipid double layers, and the ratio of the phytosterol to the vitamin E is (1-3): 1, so that the natto oligopeptide liposome has the effects that the storage of the natto oligopeptide and the stability of the natto oligopeptide in gastrointestinal and digestive tracts can be improved, the bioavailability of the natto oligopeptide liposome is improved, and the bioavailability of the natto oligopeptide liposome is improved. The traditional Chinese medicine composition has synergistic effects in the aspects of anticoagulation, thrombolysis and blood fat reduction, and has a good cardiovascular protection effect.

The invention discloses traditional Chinese medicine granules as well as a preparation method and application thereof, and belongs to the technical field of preparation of traditional Chinese medicine granules. The traditional Chinese medicine granules are prepared from extracts of traditional Chinese medicine formula raw materials, a filling agent, a disintegrating agent, a sustained release agent and a flavoring agent, wherein the traditional Chinese medicine formula raw materials are prepared from radix rehmanniae preparata, fructus corni, radix cyathulae, rhizoma alismatis, poria cocos, roasted rhizoma atractylodis macrocephalae, obscured homalomena rhizome, radix clematidis, rhizoma corydalis and liquorice root. The traditional Chinese medicine formula granules with good treatment significance on cartilage repair are obtained, the traditional Chinese medicine formula granules are convenient to carry and store and have positive treatment significance on cartilage repair, the innovative process formula has a slow release effect, and compared with a water decoction, the medicine release time is prolonged, the administration frequency can be reduced, and the life quality of a patient can be improved.

The present application relates to the technical field of medical preparation, and discloses a Russian olive leaf extract composition, a preparation method and application. The composition comprises the following components in parts by weight: 10-20 parts of Russian olive leaf extract derivative, 10-15 parts of bitter gourd extract, 10-15 parts of pueraria extract, 5-10 parts of hawthorn extract and 5-10 parts of astragalus extract. The present application also provides a preparation method. Compared with the prior art, the Russian olive leaf extract composition prepared by the present application has the effects of reducing blood sugar, blood lipid and blood pressure, and is stable in drug efficacy, mild and safe.

The preparation process of the eczema cream comprises the following steps: S1, raw material pretreatment: coarsely crushing calcined calamine; removing impurities from cortex phellodendri, coarsely crushing, and removing impurities from indigo naturalis for later use; mixing the three components, performing superfine grinding, and sieving with a 100-mesh sieve to obtain a medicinal powder raw material; s2, substrate preparation: melting and stirring beeswax and sesame oil at 85-90 DEG C, and cooling to obtain a transparent substrate; s3, mixing and forming: mixing the medicinal powder raw materials and the transparent matrix according to the mass ratio of (2.07-1): 2.13, uniformly stirring at 85-90 DEG C, cooling, solidifying, sterilizing and packaging to obtain the eczema cream. According to the standardized preparation process and the quality inspection method of the eczema cream, by optimizing superfine grinding parameters, a matrix ratio and a quality control system, stable production and quality controllability of the eczema cream are achieved, and technical support is provided for preparation conversion.

The invention discloses a hair dye mixing and discharging device which comprises a soft rubber bottle body and a mounting base, the mounting base is provided with two connecting pipes, the lower ends of the connecting pipes are connected with suction nozzle bags located in a closed cavity, hair dyes in the two suction nozzle bags are different, the mounting base is connected with a valve body, two independent fluid cavities are formed in the valve body, and the two fluid cavities are communicated with the valve body. A valve element is rotatably arranged in each fluid cavity, a strong magnetic assembly for keeping the two valve elements synchronously rotating by the same angle is arranged between the two valve elements, each valve element is provided with three valve clacks around the rotating axis of the valve element, a unit cavity is defined between every two adjacent valve clacks and the inner wall of the corresponding fluid cavity, and the lower portions of the two fluid cavities are connected with the upper ends of two connecting pipes respectively. Liquid outlet pipes are connected to the upper parts of the two fluid chambers; and a liquid mixing pipe for converging liquid discharged from all the liquid outlet pipes is arranged on the mounting seat. When the soft rubber bottle body is extruded, the two valve cores rotate synchronously, so that the hair dye which is synchronously discharged according to the proportion of 1: 1 is quickly and synchronously discharged and mixed, and the effect of the mixed hair dye product is ensured.

This application discloses a method for preparing Nutmeg and Schisandra pills to improve depression-induced arrhythmia, including the following steps: S1, take nutmeg, costus root, aucklandia root, and long pepper, in parts by weight, 20-30 parts of nutmeg, 15-25 parts of costus root, 15-25 parts of aucklandia root, and 10-20 parts of long pepper, add water for distillation extraction, and collect the obtained volatile oil. This application uses extrusion spheroidization combined with fluidized bed coating technology to prepare sustained-release microcapsules, prolonging the duration of efficacy, reducing the frequency of medication, and avoiding excessive fluctuations in blood drug concentration, thus reducing the risk of adverse reactions. The volatile oil is fully extracted by sufficient steam distillation, combined with an appropriate ratio of β-cyclodextrin inclusion and spray drying process to reduce the loss of volatile oil and ensure the stability of the formulation efficacy. The high-dose ratio of medicinal materials can not only effectively regulate the patient's mood and improve the depressive state, but also improve myocardial blood supply, stabilize cardiac electrophysiology, and break the vicious cycle between depression and arrhythmia.

The invention relates to the technical field of application of pressure sore nursing instruments, in particular to traditional Chinese medicine fumigation equipment for nursing pressure sores of a critical bedridden patient, and the traditional Chinese medicine fumigation equipment comprises a movable base, a storage mechanism, a guide pipe, a steam mechanism, an adjusting mechanism, a shifting mechanism and a height adjusting mechanism. The liquid medicine is conveyed to a water pump of a steam mechanism through a guide pipe and then is converted into steam through an atomization spray head, the automatic process of traditional Chinese medicine pretreatment, liquid medicine conveying and steam generation is achieved, frequent manual operation is not needed, the nursing efficiency is improved, meanwhile, it is guaranteed that the steam medicine effect is stable, and meanwhile the nursing effect is improved. Through mutual cooperation of the shifting mechanism, the height adjusting mechanism and the adjusting mechanism, accurate positioning and uniform sweeping of pressure sore positions are achieved, the device is suitable for pressure sore parts (such as large-area pressure sores on the back and local pressure sores on the buttocks) of different patients, the situation that steam concentrates to stimulate wound surfaces is avoided, and nursing safety is improved.

This invention provides a nematidine and ritonavir combination tablet and its preparation method. The nematidine and ritonavir combination tablet is prepared by double-layer compression of materials corresponding to the ritonavir layer and the nematidine layer. The nematidine layer is composed of the following raw materials: 280-320 parts of nematidine, 200-250 parts of compound dispersant, 60-100 parts of filler, 20-50 parts of disintegrant, 10-25 parts of binder, and 2-3 parts of lubricant. The ritonavir layer is composed of 90-110 parts of ritonavir, 30-60 parts of filler, 6-10 parts of coating material, 40-100 parts of filler, 3-5 parts of lubricant, and 200-300 parts of binder. The nematamide and ritonavir combination tablets of the present invention have small initial dissolution fluctuations, stable onset time and efficacy; at the same time, the excipients adsorb less of the active ingredients, resulting in high drug recovery rate, good efficacy and good stability.

The application relates to the technical field of first-aid kits, in particular to a clinical nursing first-aid kit, which comprises a first-aid kit main body, inner cavities are formed in the two sides of the first-aid kit main body, side boxes are fixedly connected to the inner cavities, a medicine taking and self-wiping mechanism is arranged on the side boxes, the medicine taking and self-wiping mechanism comprises a sliding plate which is slidably connected to the inside of the side box, a plurality of mark points are arranged on the sliding plate, the device is an important equipment of the biomedical engineering industry, the independent medical silica gel medicine storage opening is vertically arranged on the sliding plate, a single clamping position is used to store a lincomycin medicine bottle, medicine separation type storage is realized, the mutual collision and extrusion of the bottle bodies during the transportation, hand carrying and vehicle carrying of the box body are avoided, the problems of glass bottle fragmentation, medicine leakage, label abrasion and falling are avoided, the silica gel medicine storage opening tightly holds and limits the bottle body, external vibration conduction is blocked, the decomposition of the effective components of the medicine, the stratification and deterioration of the suspended medicine liquid are prevented, and the stability of the medicine efficacy is ensured.

The invention discloses a constant-temperature self-heating traditional Chinese medicine acupoint patch and a preparation method thereof, and belongs to the technical field of medical supplies. The traditional Chinese medicine acupoint application comprises an outermost layer, a heating layer, a bonding layer, a medicine layer and release paper, the heating layer is formed by uniformly coating a constant-temperature self-heating material, the medicine layer comprises an anti-seepage ring arranged on the sticking layer, a positioning ring matched with the anti-seepage ring and a traditional Chinese medicine preparation, and the traditional Chinese medicine preparation is traditional Chinese medicine gel or traditional Chinese medicine ointment. Wherein the constant-temperature self-heating material is prepared from the following components in parts by mass: 10 to 20 parts of reduced iron powder, 0.5 to 3 parts of vermiculite, 1 to 5 parts of activated carbon, 0.5 to 3 parts of sodium chloride, 0.1 to 2 parts of poly (N-isopropylacrylamide), 0.1 to 2 parts of hydroxypropyl methyl cellulose and 5 to 10 parts of water. The traditional Chinese medicine acupoint application disclosed by the invention can stably maintain a proper temperature for a long time, promote transdermal absorption of traditional Chinese medicine components, enhance the stimulation effect on acupoints and improve the treatment effect.

The invention discloses an application of benzalkonium bromide and chlorhexidine in prevention and treatment of plant diseases, and discloses a benzalkonium bromide and chlorhexidine compound composition which has a relatively good synergistic effect in prevention and treatment of the plant diseases and has a very good application prospect.

The invention relates to an ethychlozate suspending agent as well as a preparation method and application thereof, and belongs to the technical field of plant growth regulators. The ethychlozate suspending agent mainly comprises water and the following components in percentage by mass: 5-20% of ethychlozate, 0.5-4% of a wetting agent, 0.3-3% of a dispersing agent, 1-2% of a thickening agent, 0.05-0.1% of a stabilizing agent and 4-10% of an anti-freezing agent, the wetting agent is selected from one of a sulfate anionic wetting agent, polyoxyethylene ether and isodecyl alcohol polyoxyethylene ether; the stabilizer is selected from one of formic acid, acetic acid, citric acid, sulfamic acid, sorbitol and sodium tripolyphosphate; the pH value of the ethychlozate suspending agent is 4 to 7. The ethychlozate suspending agent disclosed by the invention is high in suspension rate and good in low-temperature stability and heat storage stability in the storage and water-added use processes, can keep the drug effect stability of ethychlozate, and can adapt to reservoir conditions of various regions with relatively large temperature difference between south and north in China.

The invention belongs to the field of starch processing, and relates to a preparation method and application of an anti-digestion corn starch complex gel polymer. The preparation method comprises the processes of plant protein pretreatment, protein cross-linking, corn starch gelatinization cross-linking and the like, the anti-digestion corn starch complex gel polymer is obtained, the dosage of cross-linking enzyme is 1-50 U / g of plant protein, the mass ratio of corn starch to plant protein is (2-8): 1, the concentration of the plant protein is controlled to be 0.01-0.05 g / mL, and the concentration of polyphenol is controlled to be 0.0005-0.002 g / mL. The anti-digestion corn starch complex gel polymer obtained by the method provided by the invention has low expansibility, excellent freeze-thaw stability and higher thermal stability, has slow digestion and resistant starch content of 40% or more, can be used as a drug sustained-release auxiliary material and a low-glycemic-index food ingredient, and has a wide application prospect. The composition has excellent physiological functions, such as improvement of intestinal health, prevention of diabetes, weight control and the like, and is widely applied.

The invention discloses a cerocaine mucilage, which is prepared from the following components in percentage by weight: 1 to 3 percent of cerocaine, 0.3 to 0.6 percent of sodium carboxymethyl cellulose, 0.1 to 0.3 percent of chitosan, 1 to 3 percent of glycerol, 0.03 to 0.08 percent of L-menthol, 0.1 to 0.6 percent of glacial acetic acid and purified water. The serocaine comprises serocaine a, serocaine b and serocaine c; the particle sizes D90 of the serocaine a, the serocaine b and the serocaine c are respectively 200 to 400 nm, 700 to 1100 nm and 1500 to 2000 nm; the dosage ratio of the sirocaine a to the sirocaine b to the sirocaine c is (1-1.5): 1: (0.5-1) according to the weight ratio. According to the prepared cerocaine mucilage, the action time is prolonged, the cerocaine mucilage is uniformly released, the drug effect is more stable, the surgical treatment requirement is met, and the stability is excellent.

The invention discloses a duplicated data removal method, system and device and a medium. The removal method comprises the steps that a first array, a second array and a count value are initialized; traversing the to-be-processed data, judging whether an identifier exists at a position corresponding to the current data in the first array or not, outputting the current data corresponding to an unidentified position as effective data, and identifying the corresponding position of the first array at the same time; wherein every time the valid data are output, the current valid data are synchronously stored in the second array in sequence, and one is added to the count value; and according to a plurality of valid data corresponding to the count value stored in the second array, completing identification emptying of a corresponding position in the first array, and returning the count value to zero at the same time. According to the invention, data deduplication can be rapidly realized through the first array, and the corresponding identification position can be rapidly found in the first array through the second array and the count value and emptying is completed, so that subsequent data can be continuously subjected to data deduplication.

The invention discloses a formula and a preparation process of an external ointment for relieving swelling and pain of bone joints. Comprising 3-9 parts of dragon's blood, 1-7 parts of frankincense, 1-8 parts of myrrh, 1-3 parts of pseudo-ginseng, 4-9 parts of ligusticum chuanxiong hort, 1-6 parts of salvia miltiorrhiza, 3-10 parts of safflower, 15-50 parts of impatiens balsamina, 2-12 parts of radix paeoniae alba, 10-35 parts of liquorice, 15-60 parts of lycopodium clavatum, 12-40 parts of pericarpium citri reticulatae viride, 12-40 parts of pericarpium citri reticulatae, 1-6 parts of centipede, 1-6 parts of ground beeltle, 3-10 parts of notopterygium root, 3-10 parts of radix angelicae pubescentis, 2-15 parts of eucommia ulmoides and 3-10 parts of radix achyranthis bidentatae. According to the ointment provided by the invention, the dragon's blood, the frankincense, the liniment, the pseudo-ginseng, the glucosamine sulfate and other components are added in the formula, so that the ointment can play a good role in relieving swelling and pain, is suitable for joint swelling and pain caused by various arthritis, and is convenient to use, stable in drug effect, good in swelling and pain relieving effect and free of toxic and side effects.

The invention provides a beta-carboline alkoxy benzene compound as well as a preparation method and application thereof. The structure of the compound is shown as a general formula I; the beta-carboline alkoxy benzene compound and the pharmaceutically acceptable salt thereof provided by the invention can be used as an HDAC inhibitor, have the advantages of good anti-tumor activity, high selectivity and low toxic reaction, and are suitable for popularization and application in preparation of drugs for treating tumors, especially application in preparation of drugs for treating colorectal cancer; # imgabs0 #

This invention discloses a black bean vinegar health-preserving composition and its preparation method, belonging to the field of health food technology. The composition consists of only two raw materials: black beans and edible vinegar, in a ratio of 40:60 to 60:40, without any excipients or additives. The preparation method includes the steps of washing black beans, cooking and cooling, sealing and soaking in vinegar solution, and bottling and preservation. This invention features a simple and novel formula, high safety, low production cost, and suitability for large-scale production. It possesses health-preserving effects such as promoting hair growth and blackening, nourishing the liver and kidneys, promoting bowel movements, and assisting in regulating blood pressure and blood lipids. Furthermore, it enjoys extensive patent protection and has broad market application prospects.

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: A: e.g., Benzene, E: e.g., -CH2-, G: e.g., a 5-membered aromatic heterocyclic ring, X: e.g., cyclohexane, J: e.g., a 5-membered aromatic heterocyclic ring, Y: e.g., a phenyl group, R1, R2, R3: e.g., a halogen atom, R4: e.g., a C1-C6 alkyl group, R5: e.g., a hydrogen atom, R6a, R6b, R6c, R6d: e.g., a hydrogen atom, R7: e.g., a hydrogen atom, R8: e.g., a hydrogen atom, n1, n2, n3: e.g., 1.

The utility model relates to a double-chamber pressurizing type pesticide spraying device, which belongs to the field of agricultural instruments and comprises a box body, a first storage tank, a second storage tank and straps, the first storage tank and the second storage tank are detachably connected to the interior of the box body, and the straps are fixedly connected to the back of the box body. A spraying mechanism which extends to the outside of the box body and is used for spraying the pesticide discharged from the first storage tank and the second storage tank in a pressurized manner is arranged in the box body, and a mixing structure which is used for uniformly mixing a single barrel of pesticide liquid is arranged outside the box body. According to the double-chamber pressurization type pesticide spraying device, the first storage tank and the second storage tank are arranged to be independent of each other, complete physical isolation of pesticides is achieved, cross contamination between the pesticides is avoided, and the stability of the pesticide effect is guaranteed; the flow proportion of the medicine discharged from the first storage tank and the second storage tank can be rapidly changed without complex cleaning and replacing operation, the switching time is greatly shortened, and the advantage that the medicine is completely physically isolated is achieved.

The present application relates to the technical field of cosmetics, more particularly to a whitening mask, comprising a mask base solution and a mask non-woven fabric, wherein the mask base solution comprises at least 3-5 parts of jojoba oil, 0.2-0.3 parts of D-pantothenyl alcohol, 5-10 parts of a filtrate of a fermentation product of schizochytrium sp., 1-3 parts of dicaprylyl carbonate, 0.5-3 parts of a whitening composition, 2-3 parts of nicotinamide, 0.01-0.3 parts of tetrahydroxypropyl ethylenediamine, 0.01-0.2 parts of tocopheryl acetate, 5.7-15 parts of an auxiliary agent, and 60-80 parts of deionized water. The whitening composition is formulated to make the base solution system of the prepared whitening mask have excellent whitening effect, effectively inhibit the activity of tyrosinase, make the skin not easy to produce melanin, and achieve the effect of effectively whitening the skin.

The invention is suitable for the technical field of drug-loaded polymer medical preparations, and provides a carbamazepine non-aqueous transdermal absorption patch and a preparation method thereof, the carbamazepine non-aqueous transdermal absorption patch comprises the following components by mass: 0.5%-10% of carbamazepine, 10%-50% of a matrix, 0.1%-1.5% of an antioxidant, 0.5%-10% of a cosolvent, 0.1%-10% of a penetration enhancer, 5%-70% of a plasticizer, and 10%-70% of a tackifier; preferably, the carbamazepine tablet comprises the following components in percentage by mass: 1%-5% of carbamazepine, 10%-30% of the matrix, 0.1%-1% of the antioxidant, 1%-5% of the cosolvent, 0.1%-5% of the penetration enhancer, 10%-50% of the plasticizer and 10%-50% of the tackifier. The prepared patch is convenient and safe to use, the compliance of a patient is greatly improved, the drug release rate is high, the oral absorption rate of carbamazepine is increased, the drug effect is stable, and clinical requirements are met.

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: A: e.g., Benzene, E: e.g., -CH2-, G: e.g., a 5-membered aromatic heterocyclic ring, X: e.g., cyclohexane, J: e.g., a 5-membered aromatic heterocyclic ring, Y: e.g., a phenyl group, R1, R2, R3: e.g., a halogen atom, R4: e.g., a C1-C6 alkyl group, R5: e.g., a hydrogen atom, R6a, R6b, R6c, R6d: e.g., a hydrogen atom, R7: e.g., a hydrogen atom, R8: e.g., a hydrogen atom, n1, n2, n3: e.g., 1.

The invention discloses a nauclea officinalis extract capsule and a production process thereof, and belongs to the technical field of capsules, the production process comprises the following steps: crushing nauclea officinalis, sieving, then adding an ethanol water solution, uniformly mixing with an extraction auxiliary material, heating, extracting, filtering, repeatedly extracting for 2-4 times, combining filtrate, and concentrating under reduced pressure to obtain nauclea officinalis extract; performing spray drying on the nauclea officinalis extract to obtain nauclea officinalis extract powder; adding the microcapsule wall material compound into water, stirring, then adding nauclea officinalis extract powder, uniformly mixing, homogenizing under high pressure, concentrating under reduced pressure after the homogenizing is finished, and then performing spray drying to obtain nauclea officinalis extract microcapsules; uniformly mixing the nauclea officinalis extract microcapsules, corn starch and microcrystalline cellulose, granulating, drying, finishing granules, adding magnesium stearate, uniformly mixing, and filling into hollow capsules to obtain the nauclea officinalis extract capsules. The nauclea officinalis extract capsule produced by the invention has good effects of clearing away heat and toxic materials, diminishing inflammation and relieving pain, and is high in bioavailability and stable in effect.

This invention discloses a theophylline sustained-release tablet and its preparation method, belonging to the field of pharmaceutical formulation technology. The technical solution includes the following steps: 1) preparation of a pore-forming agent; 2) preparation of a blocking agent; 3) premixing: anhydrous theophylline and a hydrophilic gel framework material are premixed to obtain a premixed powder; 4) first granulation: the prepared pore-forming agent aqueous solution is added to the premixed powder, granulated, dried, and sized to obtain granules one; 5) second granulation: the prepared blocking agent ethanol solution is added to granules one, granulated, dried, and sized to obtain granules two; 6) tableting: a lubricant is added to granules two, and tablets are compressed using a tableting machine to obtain theophylline sustained-release tablets. This invention provides a theophylline sustained-release tablet and its preparation method with good sustained-release effect, long duration of action, and good batch-to-batch repeatability. The preparation method is simple and requires no heating; the prepared theophylline sustained-release tablets show good compatibility with the reference formulation.

The invention relates to the technical field of medicines, and particularly discloses a pharmaceutical composition containing a cistanche deserticola extract and a microbial preparation. The pharmaceutical composition containing the cistanche deserticola extract is prepared from the following raw materials in parts by mass: 1 to 3 parts of the cistanche deserticola extract, 0.1 to 0.5 part of glutathione, 1 to 2 parts of dopamine hydrochloride and 2 to 6 parts of montmorillonite. The microbial preparation comprises the following raw materials in parts by mass: 5-12 parts of the pharmaceutical composition containing the cistanche extract, 1-2 parts of compound microorganisms, 10-20 parts of starch and 1-2 parts of superfine silica powder. The invention also discloses application of the pharmaceutical composition containing the cistanche deserticola extract or / and the microbial preparation in preparation of drugs for treating Parkinson's disease. The traditional Chinese medicine composition not only can effectively improve the motor function of Parkinson's disease patients and delay the progress of Parkinson's disease, but also is remarkable in effect, high in safety, simple in preparation method and suitable for large-scale popularization and application.

The application discloses a membrane separation and purification process of high-purity effective components of Astragalus and Angelica and a capsule preparation thereof, and belongs to the technical field of traditional Chinese medicinal material processing and preparation. The application solves the technical problems of high ash residue and low capsule bioavailability in the preparation process of the existing Astragalus and Angelica capsules. The application comprises the following steps: raw material pretreatment, countercurrent extraction, coarse filtration through a ceramic microfiltration membrane, nanofiltration separation of the filtered clear filtrate into a solvent-resistant nanofiltration membrane system, and obtaining refined Astragalus and Angelica medicinal powder after elution and drying. The application realizes the precise purification goal of "only removing impurities and not removing medicine", can reduce the inorganic ash content in the extraction liquid by more than 50%, and efficiently retains core medicinal components such as astragaloside and angelica polysaccharide. The prepared Astragalus and Angelica capsules are accurate in effective component content, have small gastrointestinal irritation, and are good in storage stability.