114 results about "Atropa belladonna" patented technology

The invention relates to the medicine field and specifically discloses an arthralgia relieving gel. The arthralgia relieving gel is prepared from raw materials including the following components in parts by weight: 160-240 parts of capsicum fluid extract, 90-140 parts of atropa belladonna fluid extract, 30-50 parts of dementholized peppermint oil, 70-90 parts of methyl salicylate, 160-240 parts of camphor, 10-15 parts of diphenhydramine hydrochloride, 1-10 parts of triethanolamine, 2-30 parts of carbomer, 1-3 parts of ethylparaben, 3-40 parts of hydroxypropyl methylcellulose, 50-100 parts of glycerin, 1-10 parts of ethanol, 1-5 parts of azone and a proper quantity of water; all the raw material components are of 1000 parts in total. The invention also discloses a preparation method of the arthralgia relieving gel. Compared with the existing arthralgia relieving plaster in the prior art, the arthralgia relieving gel has the advantages of good stability, easy absorption, remarkable medical effect, low skin irritation and safe production.

The invention discloses a preparation method of a traditional Chinese medicinal capsule. The stomach-recovering capsule is prepared from 317.5g of radix paeoniae alba, 238.1g of bletilla, 9.9g of pseudo-ginseng, 317.2g of liquorice root, 238.1g of tuckahoe, 158.7g of rhizoma corydalis, 31.7g of cuttlebone, 2.1g of extractum of Atropa belladonna and pharmaceutic adjuvant. By improvement on the process, the powder characteristic of capsule contents is improved and the gross deviation is reduced.

The invention relates to an atropa belladonna WRKY transcription factor gene and a recombinant plant expression vector and application thereof. The gene has a specific gene promoter activation role for synthesis of scopolamine, wherein the nucleotide sequence thereof is as shown in SEQ ID NO.3, and the coded amino acid sequence is as shown in SEQ ID NO.4. The AbWRKY1 gene is overexpressed in atropa belladonna, so that the content of scopolamine in atropa belladonna hairy root is increased, therefore, the gene can be applied to improvement of quality of the atropa belladonna, and can increase the content of scopolamine in the atropa belladonna.

The invention discloses a hyperostosis cold compress paste which comprises a backing layer, a gel drug layer and an anti-bonding layer, wherein the gel drug layer contains the following raw materials: sodium polyacrylate, carbomer, glycerol, dihydroxyaluminum aminoacetate, tartaric acid, purified water, medical borneol, camphor, diclofenac sodium, menthol, atropa belladonna fluid extract, clove oil, propylene glycol, glycerol, medical azone, diphenhydramine, oleum menthae and capsaicin. The invention also discloses a preparation method for the hyperostosis cold compress paste. The method comprises the following steps: preparing a gel drug and then coating the backing layer with the gel drug by machine so as to form a gel drug layer; covering the gel drug layer with the anti-bonding layer; cutting, puncturing and slicing, thereby acquiring the hyperostosis cold compress paste. No organic solvent is added into the bruise cold compress paste disclosed by the invention; the cold compress paste can be directly coated and does not need to be heated; the technology is simple and no chemical residue exists; the cold compress paste is free from irritability and stimulation, is high in drug loading capacity and moisture retention, has high compatibility with skin, is anti-ageing, has excellent weather fastness and lasting viscidity and can be repeatedly uncovered and pasted.

The invention discloses an ointment capable of removing dampness and relieving pain and a preparation method of the ointment. The ointment capable of removing dampness and relieving pain comprises the following components in parts by mass: 45-55 parts of fluid extract capable of removing dampness and relieving pain, 12-18 parts of methyl salicylate, 8-12 parts of menthol, 8-12 parts of borneol, 18-22 parts of camphor, 10-15 parts of rue fluid extract, 25-35 parts of atropa belladonna fluid extract, 185-195 parts of rubber, 60-70 parts of rosin, 2-4 parts of liquid paraffin, 265-275 parts of rubberlith, 10-15 parts of zinc oxide, 13-15 parts of yellow soft paraffin and 7-11 parts of wool fat. The preparation method of the ointment is simple, and is few in processes; the ointment is obvious in function, stable in property and low in cost.

The invention discloses a preparation method and an application of an atropa belladonna extract. The preparation method comprises processes as follows: soaking in warm water, ethanol extraction, percolation and the like. According to the medicine preparation method, the inside of a percolator is covered with multiple layers of cellulase membranes, cell walls consisting of cellulose in atropa belladonna are broken with cellulase, leaching of effective components in cells is accelerated, and the utilization rate of raw materials is greatly increased; the atropa belladonna extract prepared with the method can be taken as a novel vascular smooth muscle relaxing medicine and used for preparing medicines for treating hypertension, and a new scheme can be provided for clinical treatment of hypertension.

The invention relates to a drug for treating cancer. The drug is prepared from the following raw materials: gamboge, pine pollen, airpotato yam, periostracum serpentis, Japanese coniogramme rhizome, kiwi fruits, Portulaca grandiflora Hook., Herba Lobeliae Chinensis, Hedyotis diffusa, Scorpio, semiaquilegia adoxoides, Solanum nigrum, Arisaema cum bile, blackberry lily, catchweed bedstraw herb, Sedum lineare, plantain, viola japonica, toad, Meloe coarctatus, Calonyction muricatum, Atropa belladonna, selfheal, copperleaf herb, datura flower, yam and licorice. The drug extracts anticancer and tumor-eliminating effective ingredients from traditional Chinese medicines, has the effects of resisting cancer and eliminating tumor, diminishing inflammation and relieving pains as well as repairing organism injury, and has the advantages of low toxic or side effect, low cost and good effect.

The invention provides a belladonna liquid extract preparation method which is characterized by particularly including the steps: 1) pre-treating belladonna herbs and then impregnating the belladonna herbs by ethyl alcohol; 2) percolating the belladonna herbs after impregnation, and combining and concentrating percolating liquid; 3) sinking and filtering the concentrated percolating liquid; 4) concentrating filtrate in the step 3) into extract, performing alcohol precipitation and then filtering the extract; 5) preparing and filling the belladonna liquid extract. The invention further provides the belladonna liquid extract prepared by the method. Compared with the prior art, the method has the advantages that effective active components in the belladonna herbs can be more sufficiently extracted, purer extract can be obtained, and the belladonna liquid extract prepared by the method conforms to all regulations of pharmacopeia and has good characters, higher purity and better efficacy.

The invention provides a pure traditional Chinese medicine formulation for treating allergy and a preparation method of the pure traditional Chinese medicine formulation. The pure traditional Chinese medicine formulation is prepared from the following raw materials in parts by weight: 10-20 parts of seahorse, 20-40 parts of American ginseng, 20-40 parts of medlar, 20-40 parts of fructus jujubae, 10-20 parts of ginseng, 10-20 parts of saffron crocus, 10-20 parts of fingered citron, 10-20 parts of magnolia officinalis, 40-60 parts of hawthorn, 20-40 parts of malt, 20-40 parts of white atractylodes rhizome, 20-40 parts of radix ophiopogonis, 30-60 parts of schisandra chinensis, 20-40 parts of rhizoma atractylodis, 10-20 parts of pericarpium citri reticulatae, 20-40 parts of salvia miltiorrhiza, 20-40 parts of polygala tenuifolia, 1-5 parts of atropa belladonna, 60-80 parts of Chinese herbaceous peony, 20-40 parts of gastrodia elata, 10-20 parts of rubus parviaraliifolius hayata, 20-40 parts of mint leaf, 20-40 parts of duckweed, 10-20 parts of rhizoma smilacis glabrae, 10-30 parts of white atractylodes rhizome, 20-40 parts of radix saposhnikoviae, 20-40 parts of coix seeds, 10-20 parts of paliurus ramosissimus, 10-20 parts of astragalus membranaceus and 10-20 parts of safflower. The pure traditional Chinese medicine formulation is capable of curing patients suffering food allergy once and relieving the pain of the allergic patients; therefore, the allergic patients can intake various nutrient substance trustingly to boost immunity and enhance the disease resisting ability.

The invention relates to a Chinese medicament and western medicament combined formulation for treating cancerous diarrhea, which comprises selected Chinese medicinal materials and selected and used western medicament. The selected Chinese medicinal materials comprise the following components in portion by weight: 30 portions of medicine terminalia fruit, 20 portions of rice husk, 20 portions of nutmeg, 20 portions of angelica, 20 portions of Cinnamomum cassia, 15 grams of costus root, 30 portions of rhizoma atractylodis macrocephalae, 20 portions of radix paeoniae alba, 25 portions of radix codonopsitis and 10 portions of honey-fried licorice root, and also comprises three slices of ginger, and five dates; and the selected and used western medicament comprises spectrum antibiotic and antispasmodic, wherein the antispasmodic comprises terramycin and belladonna. The combined formulation not only can effectively control the cancerous diarrhea, but also has remarkable relieving effects on symptoms such as anorexia, emaciation and the like caused by cancer, is used for diarrhea caused by various cancers, and remarkably improves the life quality of cancerous diarrhea sufferers.

The invention discloses a production process of extractum belladonnae liquidum. The production process comprises the following steps: digging belladonna herb, removing impurities, worm damage parts, mildewing parts and non-medicinal parts, washing away silt, softening the processed parts in the sun, stacking the softened parts, arranging the products at a shady, cool and ventilated place and drying the products after sweating of a covering woven bag, cutting the dried products into sections, and carrying out pulverizing to obtain coarse powder; putting the belladonna herb coarse powder into anextraction tank, adding ethanol and an acidic pepsase solution and then carrying out airtight impregnation, collecting a primary percolate from an outlet, recovering the primary percolate into a percolating cylinder, controlling the outlet of the percolating cylinder to percolate slowly, and collecting the percolate after complete percolating out of alkaloid; carrying out ultrasonic extraction onthe percolate, recovering ethanol till alcohol smell removing of a soup, and carrying out separation to remove chlorophyll; continuously concentrating the soup without chlorophyll into a thick paste,cooling the thick paste to a room temperature, and then removing chlorophyll on the surface; stirring and diluting the thick paste with ethanol, carrying out ultrasonic extraction, and then standingfor precipitation; taking supernatant after alcohol precipitation, recovering ethanol, carrying out concentration into a thick paste, and carrying out filtering; and then adding ethanol and purified water into the atropa belladonna thick paste to prepare extractum belladonnae liquidum, carrying out filtering, putting the filtered product into a clean container, and carrying out sealing and inspecting.

The invention discloses a rheumatism cold compress paste which comprises a backing layer, a gel drug layer and an anti-bonding layer, wherein the gel drug layer contains the following raw materials: sodium polyacrylate, carbomer, glycerol, dihydroxyaluminum aminoacetate, tartaric acid, purified water, medical borneol, camphor, diclofenac sodium, menthol, atropa belladonna liquid extract, ginger oil, propylene glycol, glycerol, medical azone, diphenhydramine, oleum menthae and capsaicin. The invention also discloses a preparation method for the rheumatism cold compress paste. The method comprises the following steps: firstly, preparing a gel drug, and then coating the backing layer with the gel drug by machine so as to form the gel drug layer, coating the gel drug layer with the anti-bonding layer, cutting, puncturing and slicing, thereby acquiring the bruise cold compress paste. No organic solvent is added into the rheumatism cold compress paste disclosed by the invention; the rheumatism cold compress paste can be directly used for coating and does not need to be heated; the technology is simple and no chemical residue exists; the rheumatism cold compress paste is free from irritability and stimulation, is high in drug loading capacity and moisture retention, has high compatibility with skin, is anti-ageing, has excellent weather fastness and lasting viscidity and can be repeatedly uncovered and pasted; the production cost is lower.

The medicine composition for treating gastropathy contains the extracts of twoleaf swertia herb root, hairy birtwort root, corydalis rhizome, round cardamon seed, cablin potchouli herb and other nine kinds of Chinese medicinal materials as the active components, belladonna and pharmaceutically acceptable supplementary material. It has simple preparation process, fast acting, short treating period, high curative effect and less recurrence.

The invention relates to a hot massaging ointment capable of promoting blood circulation, removing blood stasis, dredging collaterals and relieving pain. The hot massaging ointment is prepared from the following 12 traditional Chinese medicines: a rue extract, an atropa belladonna fluid extract, frankincense, myrrh, radix linderae, rhizoma chuanxiong, radix curcumae, methyl salicylate, menthol, cinnamon oil, clove oil and camphor. Besides, the invention fuehrer relates to a preparation method of the hot massaging ointment. The preparation method mainly comprises the following steps: (1) preparing a traditional Chinese medicine extraction liquid; (2) preparing an oil phase; (3) preparing a water phase; and (4) combining the phases. The hot massaging ointment is relatively suitable for treating chronic soft tissue injury. The preparation method of the hot massaging ointment has the characteristics of strong process operability, good product reproducibility and high product yield; furthermore, the prepared hot massaging ointment has the characteristics that emulsion particle diameters are relatively small and are uniformly distributed, the transdermal absorption ratio is relatively high, and the pharmaceutical effect can be adequately developed.

The invention discloses a new process for preparing a traditional Chinese medicine belladonna liquid extract. The belladonna liquid extract is a domestic widely-used plant intermediate and clinically mainly used for gastric acid duodenal ulcer, angina of gastrointestinal tract, kidney and gallbladder and the like and has functions of removing smooth muscle spasm, restraining glandular secretion and the like. Original medicinal materials of the belladonna liquid extract are belladonna herb, and the belladonna herb is whole herb of Atropa belladonna L. A current main preparation method of the belladonna liquid extract is a percolation method, and the percolation method is long in consuming time, more in solvent consumption and insufficient in effective component enrichment. The invention discloses a process for preparing the belladonna liquid extract by ultrasonic dynamic multi-stage countercurrent extraction based on the conditions. According to the process, effective plant components are sufficiently extracted by the aid of ultrasonic cavitation effect, the dynamic multi-stage countercurrent extraction saves energy, and organic solvents are circularly used, so that the belladonna liquid extract is rapidly and effectively prepared. According to the process, an ultrasonic method is used in a dynamic multi-stage countercurrent extraction system for the first time.

The invention provides an insecticide for stevia rebaudiana. The insecticide is prepared from raw materials in parts by weight as follows: 20-25 parts of pyrethrum, 5-8 parts of tobacco stems, 25-30 parts of nerium oleander, 12-16 parts of macleaya cordata, 10-15 parts of atropa belladonna, 8-14 parts of lycoris radiate, 8-12 parts of jequirity beans, 13-17 parts of wisteria, 15-20 parts of stemona, 12-18 parts of radix aconite and 18-26 parts of phytolacca acinosa. The insecticide is obtained by combining the raw materials after the raw materials are extracted. The insecticide for stevia rebaudiana is prepared from plant raw materials, has the advantages of being green and safe, free from causing pesticide resistance, low in environment pollution and the like and has a good control effect on insect damage of stevia rebaudiana.

According to a traditional atropa belladonna planting technology, due to the fact that successive cropping obstacles exist, the environment is high in temperature and high in humidity and plant diseases and insect pests are serious, the yield is low, quality is poor and the number of pesticide residues is large. The new planting method can give the advantages of movable atropa belladonna planting into full play and increase production benefits of atropa belladonna. The method includes the steps of planting preparation, seedling culture, fixed planting, regulation and control, fertilizer and water management and harvesting.

The invention relates to a composition for reducing fish catching and transportation stress and a preparation method and application thereof, and belongs to the technical field of fishery breeding. The composition is prepared from the following components in parts by weight: 10 to 40 parts of flos daturae, 10 to 40 parts of Atropa belladonna, 5 to 20 parts of rhizoma arisaematis, 5 to 25 parts of semen ziziphi spinosae, 5 to 25 parts of pepper, 5 to 25 parts of mint and 1 to 5 parts of multivitamins. The composition has a good sedative effect, proper anesthesia depth and small damage to the liver, and can improve the immunity of live fishes, reduce caught casualties of fishes cultured in a pond, reduce the death rate of caught fishes in the transportation process and improve the survival rate of the caught fishes in temporary culture or re-culture.

The invention discloses a method for preparing an enteromorpha extract solution for inhibiting prorocentrum micans and phaeodactylum tricornutum bohlin, belongs to the technical field of medicines, in particular relates to a method for preparing an atropa belladonna extract and provides a method for preparing the atropa belladonna extract, wherein the method is short in process flow, high in product purity, sewage-free, environment-friendly and pollution-free. The preparation method comprises the following steps: by taking herba belladonnae as a raw material, crushing the raw material, adding a sulfuric acid or hydrochloric acid solution for stirring, filtering the stirred solution, adsorbing and separating the filtered solution by using resin, eluting by using an ethanol solution, and concentrating the eluate to obtain the atropa belladonna extract. Because a normal-temperature acid solution extraction method is adopted, the dissolution of chlorophyll and impurities is small, and the atropa belladonna alkaloid is easily extracted from the acid solution, so that the active ingredient content in the extracted solution is high, and fewer impurities are contained in the extracted solution.

The invention discloses a method for increasing the content of tropane alkaloid in atropa belladonna. The gene expression quantity of a TAs alkaloid synthesis pathway is effectively increased by expressing a gene rolC or rolB in the atropa belladonna, and the content of hyoscyamine and anisodamine in the atropa belladonna is increased, but variation influence is caused on plant phenotype; and thegene rolC or rolB expressed by H6H-p tissue localization does not influence plant phenotypic growth while the alkaloid content is increased. By selective control of the gene rolC or rolB, a foundationis laid for further cultivating a high-alkaloid-yield atropa belladonna strain in the medicinal field of the atropa belladonna, and a new method is provided for further developing TAs alkaloid gene engineering metabolism research of the atropa belladonna.

The invention provides a method for inducing embryogenic cells by using an Atropa belladonna L explant. The method relates to establishment of an in-vitro culture system, induction of the embryogenic cells, suspension culture of the embryogenic cells, and regeneration of plants obtained by using the embryogenic cells. The method comprises the following steps: inducing the embryogenic cells by using Atropa belladonna L aseptic seedling, propagating and subculturing the embryogenic cells, and inducing plants to regenerate by the embryogenic cells. The embryogenic cells obtained by the method can be used for producing virus-free seedling, and can produce new induction strain by using induction and mutation of a genetic material, and can be used as a transformation receptor to obtain a transformant capable of producing tropane alkaloids.

The invention discloses a formula of an ointment for activating blood, dissolving stasis and relieving pain. The formula comprises safflower, raw common monkshood mother root, raw kusnezoff monkshood root, processed strychnos nux-vomica, asarum heterotropoide, atractylodes lancea, pericarpium zanthoxyli, Chinese sapium snakes, artemisia rupestris, girald daphne bark, dragon's blood, rhizoma drynariae, lycopodium clavatum, radix rehmanniae, impatiens balsamina, rhizoma corydalis, pawpaw, cassia twigs, radix dipsaci asperoidis, aristolochia mollissima, radix clematidis, saposhnikovia divaricata, dried ginger, stiff silkworm, camphor, caulis spatholobi, borneol, datura stramonium, folium artemisiae argyi, root of angelica sinensis, atropa belladonna, polygonum cuspidatum, raw ephedra, honeycomb, elderberry, ground beetles, native copper, acacia catechu, cortex acanthopanacis, forsythia viridissima lindl, crude scorpion and achyranthes bidentata. The ointment has functions of promoting blood circulation to remove stasis, dispelling wind and eliminating dampness as well as relaxing tendon and activating blood, and can treat diseases such as hyperostosis, spondylolysis, sore and pain, tendon retraction, ankylosing spondylitis, rheumatoid arthritis, scapulohumeral periarthritis, osteoarthritis and the like.