4 results about "L-Hyoscyamine" patented technology

This invention belongs to the field of pharmaceutical technology, specifically relating to the application of a traditional Chinese medicine composition in the preparation of drugs for improving cognitive impairment. By weight, the traditional Chinese medicine composition comprises: 225-300 parts rhubarb, 50-75 parts pig bile powder, 90-120 parts aster, 360-480 parts scrophularia, 180-240 parts immature bitter orange peel, and 180-240 parts areca nut. This invention is the first to demonstrate that a composition of six traditional Chinese medicines, including scrophularia, rhubarb, and areca nut, significantly improves memory acquisition (induced by scopolamine), consolidation (induced by sodium nitrite), and retrieval impairments, covering the entire process of memory formation, encoding, storage, and retrieval, thus overcoming the limitations of existing drugs that only target a single memory stage.

This invention relates to the technical field of wound care spray formulations, providing a wound repair spray based on herbal extracts and its preparation method. The invention first uses an alkaline alcohol / aqueous solution of *Broomia spp.* leaf extract, neohesperidin, and scopolamine hydrobromide as the extraction system, employing heated ultrasonic extraction. After extraction, dilute HBr is added dropwise to adjust to a weakly acidic state, yielding an extract of *Broomia spp.* leaf extract, neohesperidin extract, and scopolamine hydrobromide extract. This extract is then compounded with extracts of *Bletilla striata*, *Ampelopsis japonica*, *Sanguisorba officinalis*, *Phellodendron chinense*, *Scutellaria baicalensis*, *Polygonum cuspidatum*, and *Platycladus orientalis* leaf extracts to obtain the wound repair spray. During the extraction process, the extract system is stable, homogeneous, clear, and transparent, without precipitation or stratification. The resulting wound repair spray is gentle on the skin and has minimal irritation to wounds. Through the synergistic effect of *Broomia spp.* leaf extract, neohesperidin, and scopolamine hydrobromide, a multi-layered closed loop of antioxidant, anti-inflammatory, blood-activating, and repairing effects is formed. Combined with the addition of natural herbal medicines, it can achieve rapid and efficient wound repair.

The application discloses a kind of drug composition for treating pseudomyopia and preparation method thereof, belong to the field of medicine.The application provides the method that scopolamine is combined with tometilcaine in the preparation of the drug for treating pseudomyopia.A kind of drug composition for treating pseudomyopia is also provided.The scopolamine tometilcaine compound eye drops of the application, active ingredients are extracted from plants and crystallized into salt, prepared into compound eye drops, curative effect is remarkable, side effect is low, process is simple, cost is low, medication, carrying, storage is convenient.

This invention provides a scopolamine-soluble press-fit acupoint patch, its preparation method, and its application. The patch includes: a fixing sheet; an adhesive sheet adhered to one side of the fixing sheet for attaching to human skin, the adhesive sheet having perforations; and a needle body comprising a fixedly connected base and a needle shaft, the base being bonded between the adhesive sheet and the fixing sheet, the needle shaft extending outward through the perforations to penetrate the stratum corneum of the skin to deliver the drug and simultaneously stimulate acupoints. At least one needle shaft is loaded with scopolamine. The fixing sheet connects to the adhesive sheet, thereby fixing the base. Compared to traditional soluble microneedle arrays, the soluble press-fit needles in this acupoint patch significantly extend the needle length, enhancing the acupoint stimulation efficacy, while achieving controlled drug release through a soluble matrix. Experiments show that this acupoint patch exhibits good behavioral improvement effects in treating a motion sickness model.