81 results about "Psoriasis patient" patented technology

A Chinese medicine for treating psorinsis, ichthyosis, tinea, neurodermatitis, urticaria, eczema, flat wart, etc is composed of the orally taken capsules prepared from 19 Chinese-medicinal materials including dahurian angelica root, etc. the exterior-applied component A prepared from 6 Chinese-medicinal materials including cloves, etc. and the exterior-applied component B prepared from said component A and 14 Chinese-medicinal materials including dahurian angelica root, etc.

The invention relates to external medicinal liquor for curing psoriasis, belonging to the traditional Chinese medicine field. The external medicinal liquor is characterized in that: the raw material medicine making active ingredients of the medicinal liquor by weight is: 10 grams of coralbean bark, 100 grams of chaulmoogra, 100 grams of fructus cnidii selinum, 90 grams of radix sophorae flavescentis and 30 grams of camphor. The raw material medicine is porphyrized, placed into a container and then added with 500 milliliters of distilled spirit to be immersed for 10 days, and then the process is completed after filtration and deslagging. The external medicinal liquor plays a part in itch removal, antipyresis and toxin expelling. The external medicinal liquor begins from the pathogenic causes of psoriasis patients and recovers the immunity function of the psoriasis patients. The external medicinal liquor is particularly suitable for various stubborn diseases which can not be cured for a long time and patients who suffer from repeated attack after stopping taking medicine, and is characterized by short treatment period, quickness in taking effect, recurrence resistance, no toxic side effect and so on. As shown by clinical verification, the itch is removed after taking the external medicinal liquor for 7 days and the cortex is softened after taking the external medicinal liquor for 15 days; and general patients only need two to four treatment periods. The effectiveness ratio of the external medicinal liquor is 100 percent and the cure rate of the external medicinal liquor is 97.6 percent.

The invention provides an external application traditional Chinese drug for treating psoriasis vulgaris. The external application traditional Chinese drug is a agent prepared from the following raw materials, by weight, 5-9 parts of densefruit pittany root bark, 5-9 parts of japanese ampelopsis root tuber, 5-9 parts of lightyellow sophora root, 9-15 parts of fructus kochiae, 5-9 parts of pinellia, 2-5 parts of amur corktree bark, 3-9 parts of common cnidium fruit, 1-5 parts of alum, 6-9 parts of stiff silkworm, 2-4 parts of chaulmoogratree seed, 9-15 parts of dried alum, 6-12 parts of mirabilite, 10-30 parts of wild buckwheat rhizome, 1-4 parts of glaber herba sarcandrae inj, 3-9 parts of japanese pogodatree flower, 2-6 parts of kansu euphorbia root, 9-15 parts of sulphur, 6-9 parts of kaempferia galanga, 3-9 parts of pomegranata rind, 6-15 parts of common bletilla tuber, 3-9 parts of podophyllum, 3-9 parts of siberian cocklebur fruit, 6-12 parts of smoked plum, 9-15 parts of flatspine pricklyash, 6-9 parts of psoralea corylifolia, 3-9 parts of common camptotheca fruit, 9-15 parts of Chinese soapberry fruit, and 1-30 parts of Chinese azalea flower. According to the traditional Chinese drug preparation of the present invention, the traditional Chinese drug five element theory is adopted, the medicine is applied aiming at the symptoms according to the psoriasis vulgaris etiopathogenisis, and the external application traditional Chinese drug has effects of heat clearing, detoxification, blood activating, and collateral dredging, and is suitable for more than 99% psoriasis vulgaris patients.

The invention relates to an externally-applied liniment for treating psoriasis, which belongs to the field of traditional Chinese medicines. The externally-applied liniment is characterized by comprising the following components in parts by weight: 10g of cortex pseudolaricis, 6g of Chinese honeylocust fruit, 5g of sulfur, 3g of realgar, 5g of mercurous chloride, 5g of borneol, 5g of camphor, 10g of crude white alum, 5g of cantharis and 20g of kuhseng. The externally-applied liniment is prepared by pulverizing the medicines, comminuting, putting into a container, adding into 500ml of white spirit, soaking for 15 days, filtering and deslagging. The invention acts as the functions of destroying parasites, relieving itching, eliminating dampness, allaying fever, expelling toxin, removing scurfs, moistening the skin and nourishing the muscle. The medicine starts with the pathogenic root of a patient with the psoriasis, restores the immunological function of the patient, especially a patient who is not recovered after long-time treatment and is easy to relapse, and has the characteristics of good curative effect, short treatment course, quick acting and little possibility of relapse. By clinical verification, the pruritus is lightened after the medicine is taken for 5 days, the cortex is softened after 13 days, and a common illness can be recovered by 2-3 treatment courses. The effective rate is 98%, and the cure rate is 86%.

A Chinese medicine in the form of particles for treating psoriasis is prepared from 13 Chinese-medicinal materials including gypsum, rehmannia root, red peony root, scutellaria root, etc. Its preparing process is also disclosed.

The invention discloses a traditional Chinese medicine lotion for treating psoriasis. The traditional Chinese medicine lotion belongs to the pharmaceutical field. The traditional Chinese medicine lotion is prepared by a stewing process with honeycomb, folium artemisiae argyi, acorus calamus, cortex phellodendri, herba schizonepetae, radix sophorae flavescentis, saposhnicovia divaricata, radix angelicae, realgar, broussonetia papeyrifera, christina loosestrife herb, galla chinensis, rhizoma smilacis glabrae, wild chrysanthemum flower, fructus kochiae, liquidambar formosana hance, fructus cnidii, fructus xanthii and tribulus terrestris as raw materials. The traditional Chinese medicine lotion is used for medicated bath of psoriasis; medicine can be absorbed through skin surface during the medicated bath. High concentration medicine active ingredients permeate the outside of cuticular cell membranes, folliculus pili, glandula sebacea, sweat duct orifices and the like gently and uniformly, and enter the body rapidly through systemic capillaries from the outside to the inside. The traditional Chinese medicine lotion has good effects for regulating of qi and blood, balancing yin and yang, dredging channels and collaterals, warming channels and expelling cold, dispelling wind and eliminating dampness, clearing heat and removing toxicity, reducing swelling and removing stasis, dredging collaterals and relieving itching, nourishing and promoting tissue regeneration, and detoxifying to remove spots.

The invention relates to the technical field of traditional Chinese medicine, in particular to sucrose-free psoriasis relieving granules and a quality detection method thereof. Due to the fact that in psoriasis relieving granules on the market at present, a large amount of sucrose is adopted as an auxiliary material, medicine selection of people suffering from hyperglycemia, hyperlipidemia and the like is limited, and application and popularization of the product are limited. The sucrose-free psoriasis relieving granules are prepared from, by weight, 182 parts of rhizoma rehmanniae, 92 parts of moutan bark, 92 parts of red peony roots, 92 parts of radix angelica sinensis, 92 parts of radix sophorae flavescentis, 92 parts of honeysuckle flowers, 92 parts of radix scrophulariae, 92 parts of fructus arctii, 46 parts of periostracum cicada, 92 parts of cortex dictamni, 46 parts of radix saposhnikoviae, 92 parts of folium isatidis, 46 parts of safflower, 450-600 parts of sucrose-free auxiliary materials and a non-sucrose flavoring agent; the sucrose-free granules are prepared according to the following method (please see the method in the description). The sucrose-free psoriasis relieving granules are a sucrose-free preparation and are good in dispersity and moisture resistance and suitable for being taken by psoriasis patients suffering from the hyperglycemia, the hyperlipidemia and the like, and convenience is provided for the psoriasis patients suffering from the hyperglycemia, the hyperlipidemia and the like. The invention further provides the quality detection method of the sucrose-free psoriasis relieving granules.

The invention relates to an externally applied medicine for the treatment of psoriasis, the psoriasis is a common chronic inflammatory skin disease and is characterized in that the epithelial cells are proliferated rapidly, thereby thickening the skin, the proliferation is similar to cancers, so the disease is also called the immortally cancer and the disease has no better treatment method at home and abroad till now. The invention provides a Chinese herbal medicine for the treatment of psoriasis, which is composed of munronia sinica, ruellia drymophila, wild red rice, stalagmite, ailanthus-like pricklyash bark, root of delavay dobinea, gaultheria yunnanensis, pseudostreblus indica bur., fruit of kwangsi dutchmanspipe and so on; the invention completely uses the Chinese herbal medicine components, and has no toxicity or side effects; furthermore, the invention has better efficacy for patients with different types of psoriasis, and the effective rate can achieve more than 98 percent.

The invention belongs to the technical field of biology, and relates to a gene marker and a detection kit for predicting the clinical efficacy of methotrexate in the treatment of psoriasis. A LCE3D SNP site rs4112788AG genotype is used as a gene marker for predicting that clinical efficacy of methotrexate in treating psoriasis. The relationship between the LCE3D SNP site rs4112788AG genotype and clinical efficacy of MTX in the treatment of psoriasis is studied. The results showed that rs4112788 genotype is related to clinical efficacy of MTX. The kit is provided to investigate the efficacy ofMTX therapy and the risk of hepatotoxicity in psoriasis patients with or without the rs4112788AG genotype at the LCE3D SNP locus, predict and evaluate the clinical efficacy of MTX in the treatment ofpsoriasis, thus guiding clinicians to formulate appropriate MTX treatment intervention program and providing a basis for improving the clinical efficacy of MTX.

The invention relates to application of arsenic trioxide in the preparation of psoriasis therapeutics. The invention is characterized in that the application refers to the use of arsenic trioxide as a main effective ingredient in the preparation of psoriasis therapeutics, including arsenic trioxide 0.01-2% by weight. The invention has the advantages that the composition is unique, the therapeutic effect is clear, good economy and safety are achieved, no significant toxic and side effect occurs, and the composition has the effects of activating blood to dredge collaterals, removing wind and evil, harmonizing ying and wei, and balancing yin and yang and is suitable for psoriasis patients to administer; clinical researches show that it is possible to significantly improve symptoms of the psoriasis patients, with 85.71% of total effective rate.

The invention discloses a traditional Chinese medicinal oral liquid for treating erythra type psoriasis, and belongs to the field of pharmacy. The traditional Chinese medicinal oral liquid for treating erythra type psoriasis is prepared through boiling 9-11% of Radix Scutellariae, 8-10% of radix paeoniae rubra, 7% of Amur Corktree Bark, 5% of unprocessed rehmannia root, 6% of sophora flower, 6% of cortex moutan, 8% of Lithospermum erythrorhizon, 6% of Herba Schizonepetae, 7% of Radix Scrophulariae, 7% of Divaricate Saposhnikovia Root, 7% of honeysuckle flower, 7% of Chinese gall, 7% of Siberian Cocklour Fruit and 8% of Chinese angelica root in a proper amount of water. The oral liquid has good efficacy of qi and blood regulating, yin and yang balancing, channel dredging, channel warming and cold dispelling, wind and dampness dispelling, heat clearing and detoxifying, swelling eliminating and blood stasis removing, vein relaxing and itch relieving, nutrition enhancing and tissue regeneration promoting, and toxin dispelling and speckle fading, and is specially used for orally treating erythra type psoriasis patients.

The invention discloses a preparation method of a traditional Chinese medicine formula for treating psoriasis. The preparation method comprises the following steps: (1) weighing the medicine by weight; (2) cleaning and soaking the weighed medicine; (3) decocting the soaked medicine in a decocting pot; (4) decocting with strong fire to boiling and decocting with slow fire; (5) adding water for decocting twice after the completion of the decoction; (6) filtering out the medicine. The preparation method of the traditional Chinese medicine composition of the invention has specific steps and scientific rigorousness in the course of the operation, and after many years of experience, the prepared medicine has obvious effect on the treatment of psoriasis, and the selected raw materials are not toxic and free of side effects. The traditional Chinese medicine formula can be used for mild and severe psoriasis patients, and is wide in application range, scientific, simple in steps, and easy to operate.

The invention relates to a psoriasis animal model and a construction method and application thereof. The construction method includes the step of carrying out imiquimod administration on the surface of animal skin to obtain the psoriasis animal model. The psoriasis animal model and the construction method and application thereof are used for animal skin for the first time to construct the psoriasis animal model; the psoriasis animal model is similar to a human psoriasis patient, and skin lesion symptoms of an administration part of the psoriasis animal model also comprise red inflammatory plaques with clear local boundaries of the skin, papules, squamous scurf or a layer of light red shiny semitransparent film and the like; after being scratched, small punctiform bleeding occurs; and the performance is highly similar to the performance of the patient, so that good clinical symptom simulation is achieved.

The invention provides a combined drug for treating psoriasis. The combined drug includes an anticholinergic drug and a sedative drug used in combination. According to the combined drug provided by the invention, the anticholinergic drug and the sedative drug are used according to a specific ratio, so that the treatment effect can be effectively enhanced, onset of psoriasis patients can be delayed, and the degree of skin damage to scalps, nails, hands and feet can be improved; the combined drug provided by the invention has little or no side effects and high safety; and at the same time, the combined drug provided by the invention can effectively treat the psoriasis, the effect is better than that of an anticholinergic drug scopolamine alone, so that results indicate that the drug providedby the invention has a synergistic effect when used in combination according to the specific ratio, and has a good clinical application prospect.

The invention discloses a traditional Chinese medicine treatment liquid for treating rash-type psoriasis, which belongs to the field of pharmacy. The traditional Chinese medicine treatment liquid comprises the following raw materials: 9-11% of realgar, 8-10% of common cnidium fruit, 8% of semen strychni, 8% of radix paeoniae rubrathe, 9% of phellodendron, 8% of lithospermum, 6% of catnip, 8% of sophora flavescens, 7% of radix saposhnikoviae, 8% of honeysuckle flower, 7% of Chinese gall, 7% of xanthium, 5% of tarragon, and a proper amount of water. The above 13 traditional Chinese medicines are decocted to prepare the traditional Chinese medicine treatment liquid for treating rash-type psoriasis, and the traditional Chinese medicine treatment liquid for treating rash-type psoriasis has good efficacy for regulating qi and blood, balancing Yin and Yang, dredging meridians, warming meridians to dissipate cold, dispelling wind and dehumidifying, clearing heat and detoxifying, diminishing swelling, dissolving stasis, relaxing vein and relieving itching, nourishing and promoting tissue regeneration, and detoxifying to remove spots. The traditional Chinese medicine treatment liquid is specially used for external washing for patients with rash-type psoriasis.

The invention discloses a traditional Chinese medicine liniment for treating psoriasis. The traditional Chinese medicine liniment is characterized by consisting of the following raw materials by weight: 10-20g of divaricate saposhnikovia root, 10-20g of cortex dictamni, 10-20g of radish skin, 10-20g of pear peel, 5-15g of Chinese blister beetle, 5-15g of sulfur, 5-15g of borneol, 5-15g of resina draconis and 5-15g safflower. The traditional Chinese medicine liniment has the effects of clearing heat, cooling blood, nourishing blood and moistening skin and promoting blood circulation to remove meridian obstruction, and after being used by patients suffering from psoriasis, the traditional Chinese medicine liniment can rapidly repair skin disease damage and activate cell tissue regeneration capacity, is exact in curative effect and fast in effectiveness and does not have toxic or side effect.

A method for predicting maintenance of response to IL-23 antibody therapy and treating a patient having psoriasis with extended dosing intervals after measuring at least one indicator from psoriasis patients before and during treatment with an IL-23 antibody is useful in the treatment of psoriasis.

The invention discloses a traditional Chinese medicine composition for treating psoriasis. The traditional Chinese medicine composition is prepared from the following materials in parts by weight: 15-20 parts of radix scutellariae, 15-20 parts of poria cocos, 10-15 parts of rhizoma bletillae, 10-15 parts of cortex dictamni, 8-12 parts of Chinese lobelia, 8-12 parts of cortex lycii radicis, 6-10 parts of geranium wilfordii, 6-10 parts of caulis sinomenii, 5-10 parts of Chinese violet and 5-10 parts of notopterygium root. The traditional Chinese medicine composition disclosed by the invention can effectively relieve the illness state of a psoriasis patient, is short in course of treatment, can radically treat psoriasis, is high in cure rate, free of relapse, safe and free of toxic and side effects.

The invention relates to an external Chinese medicinal composition for treating psoriasis, which consists of the following raw materials in part by weight: 25 to 30 parts of bitter almond kernel, 25 to 30 parts of chaulmoogratree, 8 to 10 parts of croton seed, 0.3 to 0.5 part of blister beetle, and 0.3 to 0.5 part of hydrargyri oxydum rubrum. The raw materials are ground into fine powder together by weight and uniformly mixed with sesame oil for external use. The composition has the advantages of simple treatment method, convenient medication, obvious medicinal effect, no side effects, short treatment course, and complete eradication; and clinical observation of 2,000 psoriasis patients proves that the composition has a cure rate of 92 percent, and prevents relapse.