166 results about "Patients symptoms" patented technology

A device and method to detect and manage heart failure patient symptoms is provided. Respiration and/or cardiac parameters may be sensed or observed to determine the status of a patient's condition. These symptoms may be classified for appropriate patient disease management. A patient's activity level may be monitored in conjunction with respiration and/or cardiac parameters to provide additional patient status information. These symptoms may be classified for appropriate patient disease management. Pulmonary edema is one condition that may be determined to exist when a respiration parameter is out of range for a given sensed activity level. If edema is determined to be present, the device may be configured to respond to treat the edema.

This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.

This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.

The present disclosure relates to devices and methods for implanting a prosthesis into a heart of a mammal, such as a person. The disclosure includes a prosthesis that acts as a pressure vent between the left and right atria of the heart. The intracardiac pressure vents disclosed allow sufficient flow from the left atrium to the right atrium to relieve elevated left atrial pressure and resulting patient symptoms. The devices also limit the amount of flow from the right atrium to the left atrium to minimize the potential for thrombi or other embolic material from entering arterial circulation.

An active suture that can be used for both wound closure and the delivery of therapeutic fluids to the tissue surrounding a wound is disclosed. The active suture may include a connector designed to join a fluid source, such as a syringe or conventional IV delivery system, to an internal passageway that is embedded within a braided suture. The internal passageway may be comprised of a fine polymeric tube and is capable of conducting and emitting a fluid into at least a portion of the braided suture and surrounding tissue. The invention enables delivery of an efficacious volume of drug bearing solution on the order of milliliters per day, provides a high level of fluid delivery rate control enabling the physician to start or stop drug administration at his/her discretion, and offers a means of providing more than one type of medication that may be selected post-surgically in accord with unexpected patient symptoms that may arise.

The present disclosure relates to devices and methods for implanting a prosthesis into a heart of a mammal, such as a person. The disclosure includes a prosthesis that acts as a pressure vent between the left and right atria of the heart. The disclosure also includes a mounting tool for mounting the prosthesis onto a loading tool, the loading tool useful for loading the prosthesis onto a device for delivering the prosthesis into the patient's heart. Control devices and methods for using these devices are also disclosed. The intracardiac pressure vents disclosed allow sufficient flow from the left atrium to the right atrium to relieve elevated left atrial pressure and resulting patient symptoms. The devices also limit the amount of flow from the right atrium to the left atrium to minimize the potential for thrombi or other embolic material from entering arterial circulation.

An active suture that can be used for the delivery of therapeutic fluids to the tissue surrounding a wound is disclosed. The active suture may include a connector designed to join a fluid source, such as a syringe, conventional IV delivery system, or infusion pump to an internal passageway that is embedded within a braided suture. The internal passageway may be comprised of a fine polymeric tube and is capable of conducting and emitting a fluid into at least a portion of the braided suture and surrounding tissue. The invention enables delivery of an efficacious volume of drug bearing solution on the order of milliliters per day, provides a high level of fluid delivery rate control enabling the physician to start or stop drug administration at his/her discretion, and offers a means of providing more than one type of medication that may be selected post-surgically in accord with unexpected patient symptoms that may arise.

A system for monitoring drug dispensation and drug effects on physiological signals or implantable medical device (IMD) performance is provided. The system includes a drug dispenser adapted for telemetric communication with an IMD, an IMD capable of acquiring time-based physiological or device performance data, and a programmer/monitor for receiving and displaying IMD-acquired data and drug dispensation data. The system may further include a patient activator for transmitting signals indicative of symptoms experienced by a patient associated with a side-effect caused by a drug or a condition for which the drug has been prescribed to treat. In an associated method, a drug dispensation signal is generated upon activation of the drug dispenser. IMD-acquired data, drug dispensation data, and patient symptom data are retrieved by a programmer/monitor. IMD-acquired data is combined with or grouped according to drug dispensation data and displayed.

A system for using functional magnetic resonance imaging (fMRI) for detecting symptoms indicative of Alzheimer's disease, diagnosing Alzheimer's disease and gauging the efficacy of medications used in treating Alzheimer's disease. The system includes steps involving activating a selected region of the brain which may be affected by Alzheimer's disease using an identity recognition type task, concurrently acquiring task-active MRI data responsive to the task, comparing the patient's task-active MRI data to reference data derived from a database of task-active data from healthy individuals and detecting whether the patient has symptoms related to Alzheimer's disease. The severity of the patient's symptoms and the staging of the disease may also be determined. Also, a medication may be administered to the patient and the efficacy of the medication may be gauged based on the severity of the patient's symptoms.

A method and system for creating a database for diagnosis determination that includes receiving baseline symptoms in a memory, receiving diagnoses in the memory, classifying the diagnoses that correspond to the baseline symptoms as diagnoses linked to the baseline symptoms, and rendering the diagnoses accessible on the basis of the corresponding baseline symptoms. A method and system for determining a diagnosis and treatment that includes receiving patient symptoms, comparing patient symptoms to previously stored baseline symptoms, identifying the patient symptoms that correspond to the baseline symptoms, and providing diagnoses that correspond to the identified patient symptoms to a user.

A system (500) for automated clinical diagnosis includes: a knowledge graph (310, 510) generated using a curated corpus of medical information (520) and comprising a plurality of nodes; a user interface (512) configured to receive input comprising information about at least one patient symptom (316) and at least one patient demographic parameter (318); and a processor (530) configured to extract the at least one patient symptom and demographic parameter, and further configured to: (i) weight the extracted patient symptom; (ii) query the knowledge graph to generate a diagnosis graph as a subset of the knowledge graph; (iii) identify a ranked list of medical conditions for the patient from the diagnosis graph; and (iv) adjust, based on the extracted at least one demographic parameter about the patient, the ranking of the ranked list; wherein the identified medical conditions are provided to the user via the user interface.

A system based on the use of fMRI techniques for use in detecting neurological abnormalities indicative of Attention Deficit Hyperactivity Disorder (ADHD), in determining the severity of ADHD and in gauging the efficacy of medications used in treating ADHD. The system includes the steps of activating a selected region of the brain which is known to be affected by ADHD using a working memory and sustained attention task such as an N-Back task and concurrently acquiring fMRI image data responsive to the task. The patient's task-active fMRI data is then compared to reference fMRI data derived from a database of task-active fMRI data acquired from healthy individuals and determining whether the patient has symptoms related to ADHD. The extent of the patient's ADHD related symptoms and the severity of the disorder may also be assessed. Additionally, patients who are affected by ADHD may be administered medications intended to address their symptoms and based on comparing the severity of the patient's symptoms on and off therapy, the efficiency of the medication may be gauged and a measure may be provided of how well individual patients respond to a given medication.

A system for monitoring drug dispensation and drug effects on physiological signals or implantable medical device (IMD) performance is provided. The system includes a drug dispenser adapted for telemetric communication with an IMD, an IMD capable of acquiring time-based physiological or device performance data, and a programmer/monitor for receiving and displaying IMD-acquired data and drug dispensation data. The system may further include a patient activator for transmitting signals indicative of symptoms experienced by a patient associated with a side-effect caused by a drug or a condition for which the drug has been prescribed to treat. In an associated method, a drug dispensation signal is generated upon activation of the drug dispenser. IMD-acquired data, drug dispensation data, and patient symptom data are retrieved by a programmer/monitor. IMD-acquired data is combined with or grouped according to drug dispensation data and displayed.