6 results about "Belladonna extract" patented technology

This invention discloses a method for refining and desalting belladonna fluid extract, relating to the field of traditional Chinese medicine pharmaceuticals. Belladonna grass is pulverized through a 24-mesh sieve to form coarse powder. The powder is percolated using ethanol as a solvent to obtain a primary belladonna extract. The ethanol is recovered from the primary extract, and the extract is cooled to room temperature. Chlorophyll is removed by separation using a ceramic membrane. The extract is then filtered, and the filtrate is concentrated using an organic nanofiltration membrane to remove salts. The membrane filtrate is further concentrated under reduced pressure to a thick paste. Seven times the volume of ethanol is added and stirred until homogeneous. The mixture is allowed to stand until complete precipitation. The supernatant is collected, and the ethanol is recovered and concentrated to a thick paste. Based on the content determined in the thick paste, an appropriate amount of 85% ethanol is added, and the mixture is diluted with water to prepare a finished belladonna fluid extract product conforming to pharmacopoeia standards. This method is stable and reliable, avoids high-temperature degradation of the active ingredients, effectively removes impurities from the belladonna fluid extract, and prevents salt precipitation in the finished product. This ensures its efficacy and medication safety, and has broad market application prospects.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition with the function of relieving stomach inflammation and a preparation method and application. The traditional Chinese medicine composition comprises a main medicine and an auxiliary medicine, the main medicine consists of cuttle bone, thunberg fritillary bulb and rheum officinale; the adjuvants comprise a first adjuvant and a second adjuvant; the first adjuvant is belladonna and daphniphyllum calycinum; the second adjuvant comprises fructus aurantii and cortex magnoliae officinalis. The traditional Chinese medicine composition provided by the invention is simple in component, only a trace amount of belladonna extract needs to be added, meanwhile, daphniphyllum calycinum is compounded, the addition of excessive other unnecessary components is avoided, and the symptom of chronic non-atrophic gastritis with erosion can be remarkably improved.

The invention discloses a medicine formula capable of treating various gastrointestinal diseases, and relates to the technical field of medicine formulas. According to a medicine formula capable of treating various gastrointestinal diseases, skin and smooth muscle are regarded as the same muscular tissue, the smooth muscle function is indirectly improved by adjusting the skin state, a medicine composition for treating digestive system diseases is developed based on the theory, and the medicine composition comprises 1 g of baked ginger powder, 4 mg of belladonna extract and 5 mg of desloratadine. The method specifically comprises the following steps: shredding 100g of baked ginger, baking at 150 DEG C for 30 minutes until the baked ginger is brown, grinding, and sieving with a 80-mesh sieve; 1 g of baked ginger powder, 4 mg of belladonna extract and 5 mg of desloratadine are mixed in proportion and pressed into tablets, and the weight of each tablet is 1.1 g. The traditional Chinese medicine composition can effectively treat various gastrointestinal diseases including stomachache and diarrhea, acute and chronic gastroenteritis and deficiency-cold diarrhea, the treatment rehabilitation rate reaches 60-80%, the cost is not complex, the formula is prepared according to the principle that skin and smooth muscle are similar in multiple aspects, and the traditional Chinese medicine composition is an gastrointestinal medicine with an obvious treatment effect.

The invention relates to an enteric analgesic suppository for treating haemorrhoids and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine suppositories. The haemorrhoid relieving enteric-coated analgesic suppository is prepared from the following raw materials in parts by weight: 23 to 28 parts of vinegar-processed rhizoma corydalis, 23 to 28 parts of radix angelicae, 2 to 5 parts of borneol, 1 to 2 parts of belladonna extract, 3 to 6 parts of nefopam, 8 to 12 parts of diclofenac sodium, 0.5 to 1 part of meloxicam and 160 to 190 parts of matrix. The traditional Chinese medicines and the western medicines are reasonably configured by analyzing the mechanism of the medicine effect on nerves, the related nerves are influenced from different levels, the mechanism of generating local pain is inhibited or blocked from different angles and different levels, the synergistic analgesia is realized, the obvious analgesic and anti-inflammatory effects are realized, the obvious stimulation to local tissues is avoided, and the safety is good. The suppository analgesic can directly introduce the medicine into an action target position to play a local effect, so that the influence of the medicine on the whole body is reduced.

The invention discloses a processing method for preparing belladonna extract from belladonna grass, and belongs to the technical field of belladonna extract processing. The present invention is used to solve the technical problems that the fat-soluble impurity content in the prior art belladonna extract is high and the belladonna extract in belladonna grass is difficult to be extracted and separated, and the extraction rate of belladonna extract needs to be further improved. A processing method for preparing belladonna extract from belladonna grass includes the following steps: after washing belladonna grass with water, hanging it in an oven, setting the temperature to 50-60°C, drying it for 20-24h, transferring belladonna grass to a grass cutter, processing belladonna grass raw material into fine powder, and obtaining belladonna grass one; adding belladonna grass one and washing solution to a flask, stirring at room temperature for 30-50min, filtering, transferring the filter cake to a drying oven with a temperature of 50-60°C, and drying it with blast air for 6-8h to obtain belladonna grass two. The present invention not only effectively improves the extraction rate of belladonna extract from belladonna grass, but also can remove fat-soluble impurities on belladonna grass and improve the alkaloid content in belladonna extract.

The invention provides a vitamin U belladonna aluminum capsule, which is characterized in that a belladonna extract is adsorbed in pores of a mixture of a mannitol cross-polymerized barley-mountain co-treated material phemaburst # imgabs 0 # mesoporous silica # imgabs 1 #, and the mixture provides a weak acid environment for the belladonna extract. The weak acid environment can improve the stability of atropine; meanwhile, the rapid desorption of the belladonna extract can be met, so that the capsule is rapidly disintegrated; in addition, migrated moisture in a gelatin capsule shell can be locked preferentially, the stability of the vitamin UII is improved, and an acceleration test proves that the product obtained by the invention can have better dissolution behavior and stability and is obviously superior to that of an existing preparation.