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217results about How to "Fast onset" patented technology

Long-acting slow-release pharmaceutical preparation and preparation method thereof

The invention discloses a long-acting slow-release pharmaceutical preparation. The pharmaceutical preparation contains the following components in percentage by weight: 25%-60% of a water-insoluble or sparingly-soluble drug and 40%-75% of a high-molecular polymer. After the pharmaceutical preparation is subjected to one time of intramuscular injection administration, the rate of a maximum plasma concentration to a minimum plasma concentration in a main release period is less than 5; the slope of a linear trend line of a cumulative release curve is less than 8 under an in-vitro simulated release condition; the daily release amount is less than 8.5%; and the simulated release condition is a buffer solution with the temperature of 37+/-0.5 DEG C and the pH of 6.8-8.4. The prepared long-acting slow-release pharmaceutical preparation has the beneficial effects that an obvious release delay period or a burst release phenomenon are avoided after the administration, the steady state plasma concentration can be rapidly achieved, the plasma concentration with a relatively small fluctuation range can be maintained in several weeks or longer through once administration, and the pharmaceutical preparation can take effect rapidly and has good compliance with a patient.
Owner:AC PHARMA CO LTD

Zolmitriptan tongue tablet

The invention provides a zolmitriptan sublingual tablet, which is characterized in that it contains the main drug zolmitriptan, a disintegrating agent and a filler. In every 1000 sublingual tablets, the content of zolmitriptan is 1 -50g, the content of disintegrating agent is 2-20g, the content of filler is 40-200g; it also contains 0-20g of corrective agent, 10-60g of binder and 0.5-5g of lubricant. The present invention utilizes the characteristics of non-keratinized sublingual mucosa, rich capillaries, and fast blood flow, aiming at the absorption of zolmitriptan ordinary tablets through the gastrointestinal tract, slow onset of action, first-pass effect, and low bioavailability. The deficiencies of advanced prior art, zolmitriptan is made into sublingual tablet, can make it absorb through sublingual mucosa, directly enter blood circulation through jugular vein and superior vena cava, take effect rapidly; Avoid oral administration The first-pass effect improves bioavailability and ensures curative effect. Moreover, water is not needed when taking the medicine, and it is placed under the tongue to contain it, so it is convenient to take and has a good taste. With the characteristics of rapid onset of action, convenient administration and high bioavailability, it can provide patients with a new treatment option and fill the gap in the market.
Owner:重庆医科大学医药研究所

Wet tissue with effects of activating blood circulation, dispersing stasis and relieving swellings and pain

InactiveCN104352726ACtiveHas the effect of reducing swelling and relieving painAntipyreticAnalgesicsWhole bodyAdditive ingredient
The invention discloses a wet tissue with the effects of activating blood circulation, dispersing stasis and relieving swellings and pain and relates to technical field of wet tissue production. The wet tissue consists of a wet tissue matrix and a base solution attached to the matrix, wherein the base solution is prepared from the following raw materials in parts by mass: 50-65 parts of pseudo-ginseng, 30-40 parts of curculigo sinensis, 30-35 parts of dipsacus asper, 20-30 parts of murraya, 20-25 parts of pink reineckea herb, 15-20 parts of claoxylon polot merr, 15-20 parts of sappanwood, 10-15 parts of semen vaccariae, 15-25 parts of gendarussa vulgaris, 10-15 parts of garden balsam stem, 5-10 parts of notopterygium root, 10-15 parts of magnoliae officinalis, 5-10 parts of scarlet kadsura root and 5-10 parts of cortex periplocae. The wet tissue with the effects of activating blood circulation, dispersing stasis and relieving swellings and pain is prepared by using natural Chinese herbal medicines as raw materials, and the medicinal ingredients enter the body from the skin, and can perform a local therapeutic effect and achieve the purpose of treating the whole body. The wet tissue rapidly takes effect, does not have adverse reaction, and is convenient to carry and use.
Owner:铜陵麟安生物科技股份有限公司

Holographic circulation repair pain-relieving external medicinal liquor for treating internal and external injury pain and preparation method thereof

InactiveCN110115751AImprove efficacyEliminate pesticide residuesNervous disorderAntipyreticCarthamusCentipede
The invention relates to a holographic circulation repair pain-relieving external medicinal liquor for treating internal and external injury pain and a preparation method thereof, and belongs to the technical field of preparation of traditional Chinese medicines. The external medicinal liquor comprises liquor and Chinese herbal medicines, wherein the Chinese herbal medicines comprise, by weight, 10-30 parts of raw radix aconite, 10-30 parts of raw radix aconiti agrestis, 10-30 parts of resina draconis, 10-30 parts of scorpions, 10-30 parts of centipedes, 10-30 parts of earthworms, 10-30 partsof ground beetles, 10-60 parts of notopterygium root, 10-50 parts of cassia twigs, 10-50 parts of divaricate saposhnikovia root, 10-50 parts of rhizoma cyperi, 20-60 parts of suberect spatholobus stems, 20-60 parts of common clubmoss herb, 20-80 parts of phryma leptostachya, 20-60 parts of caulis pipers futokadsurae, 20-60 parts of caulis sinomenii, 20-80 parts of radix cyathulae, 20-80 parts of dipsacus asperoids, 20-80 parts of rhizoma cibotii, 20-60 parts of radix curcuma, 30-100 parts of raw radix astragali, 20-60 parts of white peony root, 20-60 parts of polygonum cuspidatum, 20-60 partsof safflower and 20-60 parts of radix angelicae pubescentis. The addition amount of the liquor is 8-15 times of the total weight of the Chinese herbal medicines. The external medicinal liquor can be used for treating various kinds of arthralgia and myalgia, and also can be used for conditioning and treating diseases of digestive systems, heart and brain systems and the like.
Owner:北京德氧生健康文化传播有限公司

Multifunctional compound fermentation inoculant and preparation method and application thereof

The invention relates to a multifunctional compound fermentation inoculant and a preparation method and application thereof. The multifunctional compound fermentation inoculant comprises the following components in parts by weight: 5 to 15 parts of bacillus megatherium, 3 to 12 parts of bacillus licheniformis, 4 to 15 parts of bacillus amyloliquefaciens, 5 to 17 parts of bacillus pumilus, 8 to 20 parts of pseudomonas putida, 5 to 15 parts of bacillus mucilaginosus, 1 to 5 parts of aspergillus niger, 3 to 10 parts of aspergillus oryzae, 1 to 8 parts of paecilomyces lilacinus, 3 to 12 parts of trichoderma, 3 to 10 parts of streptomyces jingyangensis, 2 to 8 parts of candida utilis and 3 to 12 parts of lactic acid bacteria. Compared with the prior art, the fermentation inoculant disclosed by the invention can be mutually matched in each stage of organic waste fermentation; the fermentation inoculant is rapid to respond, has high-temperature tolerance, efficiently kills pathogenic microorganisms, can be used for preparing a bio-organic fertilizer prepared by fermenting traditional raw materials such as livestock and poultry manure and straw, can also be used for fermenting kitchen waste, municipal sludge and the like to form an organic fertilizer raw material, and has a wide application prospect.
Owner:上海又然生态科技有限公司 +1
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