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Composition and soft capsule for alleviating cough

A technology of composition and soft capsule, which is applied in the field of composition for relieving cough, can solve the problems of central nervous system excitement and addiction, and achieve the effect of good stability, good curative effect and reasonable content ratio

Inactive Publication Date: 2014-09-03
安士制药(中山)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Moreover, in the process of existing antitussive drugs, the central antitussive effect is achieved by suppressing the cough reflex, and there are also side effects such as excitement to the central nervous system, and some can even become addictive; Amines and sleep-promoting compositions await further improvement

Method used

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  • Composition and soft capsule for alleviating cough
  • Composition and soft capsule for alleviating cough
  • Composition and soft capsule for alleviating cough

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The composition for relieving cough of the present invention comprises the following components by weight percentage:

[0044] Benzonatate 85%

[0045] Polyethylene Glycol 15%

[0046] Wherein said polyethylene glycol is the mixture of polyethylene glycol 400 and polyethylene glycol 600.

Embodiment 2

[0048] The composition for relieving cough of the present invention comprises the following components by weight percentage:

[0049] Benzonatate 85%

[0050] Polyethylene glycol 5.0%

[0051] Polyol 10%

[0052] Wherein said polyethylene glycol is polyethylene glycol 200; said polyhydric alcohol is the mixture of glycerol and propylene glycol.

Embodiment 3

[0054] The composition for relieving cough of the present invention comprises the following components by weight percentage:

[0055] Benzonatate 90%

[0056] Polyol 10%

[0057] Wherein said polyhydric alcohol is glycerin.

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Abstract

The invention discloses a composition and a soft capsule for alleviating cough. The composition for alleviating cough comprises the following compositions in percent by weight: 30-100% of benzonatate, 0-60% of polyethylene glycol and 0-50% of polyol. The soft capsule comprises a soft-capsule shell and a contained substance cladded by the soft-capsule gelatin shell. The contained substance comprises the following compositions: benzonatate, polyethylene glycol and polyol. The soft-capsule gelatin shell is composed of gelatin, a plasticizer, purified water and a coloring agent. The composition for alleviating cough is simple in compositions, stable, effective, and rapid in dissolving and absorption. The soft capsule containing the above composition for alleviating cough is also provided. The soft capsule is applicable to irritable cough, paroxysmal cough and the like caused by acute bronchitis, bronchitis asthma, pneumonia and lung cancer, and is applied to prevent cough when fiberoptic bronchoscopy and laryngoscopy are performed.

Description

technical field [0001] The invention relates to a composition for relieving cough, and also relates to a soft capsule containing the composition. Background technique [0002] Cough is a major symptom of respiratory disease. Cough is a protective reflex, which can promote the discharge of sputum and foreign bodies in the respiratory tract, and keep the respiratory tract clean and unobstructed. [0003] For severe cough without sputum, such as chronic cough caused by upper respiratory tract virus infection or cough that has not been relieved after treatment, in order to alleviate the suffering of the patient, prevent the development of the primary disease, and avoid complications caused by severe cough, Antitussive drugs should be used for treatment. [0004] Drugs used to relieve cough. Divided into two types: [0005] ①Central antitussives. It directly inhibits the medulla oblongata cough center, making it less sensitive to peripheral stimuli, and has a certain effect ...

Claims

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Application Information

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IPC IPC(8): A61K31/245A61K9/66A61P11/14
Inventor 余凯琳贾卫东
Owner 安士制药(中山)有限公司
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