The invention relates to an aweto medicated wine and process for preparation, which belongs to the nourishing and health preserving field. The invention comprises aweto, poria cocos, Chinese yam, eucommia ulmoides, alpinia oxyphylla, wolfberry fruit, radix adenophorea, cuscuta chinensis, liriope, tortoises shell, sucrose and sorghum wine whose alcohol is 42-54 degrees (v / v). In the process of preparation, the herbal medicines are immersed in the wine, and sealed to store for 30-50 days at normal temperature, then solid and liquid-state admixture is separated, and the supernatant which is obtained is a desired product. The invention has no toxin and side effect, and has the functions of moistening lung to stop coughing, nourishing liver and kidney, replenishing essence to improve vision, strengthening essence to invigorate vital energy, nourishing yin and promoting glandular secretion, nourishing spleen and strengthening stomach, anchoring mind and diuretic, lowering blood pressure anddecreasing blood glucose, reinforcing blood circulation and the like. The invention can be used not only for health care but also for treatment.