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Neomycin sulfate is an antibiotic drug that effectively kills or inhibits bacteria in humans and animals. Applied orally, neomycin sulfate is used to treat infections of the intestine and as a preliminary treatment before gastrointestinal surgery.
A medicine for treating scald infection and its preparation method and use
The application belongs to the technical field of biological medicine, and particularly relates to a drug for treating scald infection and a preparation method and application thereof. The application prepares a drug for treating scald infection, which is self-assembled from a tetrahedral framework nucleic acid and an antibiotic. The application preferably selects a tFNAs-NeoS drug, the drug has a simple preparation method, a high loading efficiency of neomycin sulfate, good stability in a complex biological medium, reduced cytotoxicity and effective dose of the antibiotic NeoS, better biological safety than tFNAs, and slowed generation of bacterial drug resistance. In terms of treating scald wound infection, the tFNAs-NeoS has better effects of promoting wound healing and biological safety than NeoS. Therefore, the prepared tFNAs-NeoS overcomes the problem of overuse of antibiotics, and has a good clinical application prospect.
Owner:SICHUAN UNIV