2 results about "Wedelia" patented technology

The invention belongs to the technical field of aquaculture, and discloses a neomycin sulfate composite synergist as well as a preparation method and application thereof. The invention discloses application of wedelia chinensis extract, gastrodia elata extract and picrasma quassioides extract in inhibiting vibrio growth in vitro and preventing and treating penaeus vannamei glass seedling disease caused by vibrio infection for the first time. Experimental verification shows that when the wedelia chinensis extract, the gastrodia elata extract and the picrasma quassioides extract are independently used, combined pairwise or used at the same time, the good effect of inhibiting vibrio growth in vitro is achieved. Meanwhile, aiming at the treatment of the problem of vibrio infection causing glass seedlings, the extract is combined with neomycin sulfate for use, so that the objective problem of weak or low efficiency of neomycin sulfate according to recommended dosage is solved, the effect of the neomycin sulfate is enhanced after the extract is combined with the neomycin sulfate, and the use amount of the neomycin sulfate is reduced.

This invention belongs to the field of pharmaceutical formulation technology and provides a topical formulation for herpes lesions and its preparation method. This invention employs a synergistic design of three nanocarriers: a polyvinyl alcohol and sodium alginate composite film-forming matrix, core-shell nanoparticles N1 (chitosan-sodium tripolyphosphate ion-crosslinked core + tannic acid-coated shell), plant polyphenol-phospholipid composite nanoparticles N3 (lecithin composite of Phyllanthus urinaria and Wedelia trifoliata alcohol water extract), and agarwood volatile oil-cyclodextrin inclusion complex N2 (agarwood volatile oil O and hydroxypropyl-β-cyclodextrin inclusion complex). This achieves low viscosity (2-80 mPa·s) and uniform spraying performance that can be atomized by a mechanical pump, dense film coverage and wet-state erosion resistance, and sustained drug release and dispersion stability under high load of multiple nanocarriers. It solves the technical contradiction of existing systems in balancing low viscosity atomization, film density, multi-carrier stability, and low irritation, and has broad application value.