34 results about "Diphenoxylate" patented technology

A composition comprising the tannate of an opioid. Suitable opioids include alfentanil, buprenorphine, butorphanol, carfentanil, cocaine, codeine, dezocine, diacetylmorphine, dihydrocodeine, dihydromorphine, diphenoxylate, diprenorphine, etorphine, fentanyl, heroin, hydrocodone, hydromorphone, beta-hydroxy-3-methylfentanyl, levo-alpha-acetylmethadol, levorphanol, lofentanil, meperidine, methadone, morphine, nalbuphine, nalmefene, o-methylnaltrexone, naloxone, naltrexone, oxycodone, oxymorphone, pentazocine, pethidine, propoxyphene, remifentanil, sufentanil, tilidine and tramadol. The opioid tannate may be readily prepared by reacting an opioid free base with tannic acid, either neat or in the presence of up to about 30 wt. % water, at a temperature of about 60 to about 150° C. and thereafter recovering the resultant opioid tannate. The opioid tannate may also be prepared by an alternative process that involves reacting the opioid free base with water at a temperature such that not more than about 10 wt. % of the opioid tannate will be decomposed and thereafter removing the water by freeze-drying.

The invention discloses a compound medicine for preventing and treating enteritis of poultry, which contains the following constituents by mass percent: 10-40% of antibiotics, 0.1-1% of obstruent, 2-12% of intestinal mucosa protector, and the balance of auxiliary material. The antibiotics constituent in the compound medicine is one or more of aminoglycosides, polymyxins and berberine hydrochloride. The obstruent is one of scopolamine methobr, atropine, diphenoxylate, loperamide and bismuth subnitrate, or combinations of more. The intestinal mucosa protector is one of vitamin K3, cimetidine and glutamine, or combination of more. The auxiliary material is one of oral glucose, anhydrous glucose, soluble starch, dextrin and cyclodextrin, or combination of more. The invention further discloses a preparation method of the compound medicine for preventing and treating enteritis of poultry.

The invention relates to a medicine for treating infantile diarrhea, and in particular relates to a compound medicine for treating infantile diarrhea and a preparation method of the compound medicine. The medicine disclosed by the invention is prepared by taking glucurone, tannalbin and compound diphenoxylate as raw materials. The preparation method disclosed by the invention comprises the steps of evenly mixing the raw materials to prepare 100-120 meshes of powder, sterilizing and disinfecting, bagging and then sealing to obtain the medicine. The medicine for treating infantile diarrhea has the advantages of good curative effect, quick effect and no toxic and side effects.

The invention discloses a medicine for treating chronic colitis, which has the following medicine composition: Codonopsis pilosula, Atractylodes macrocephala, moxibustion licorice, angelica, white spoon, cinnamon, nutmeg, woody fragrance, myrobalan, millet shell, dried ginger , Compound Diphenoxylate Tablets, Sulfasalazine Tablets. It has the effects of invigorating the spleen and replenishing qi, invigorating qi and promoting blood circulation, nourishing qi and invigorating the middle, warming the middle and dispelling cold, reducing astringency and relieving diarrhea, reducing inflammation and relieving pain, levating the anus and stopping prolapse. The process is simple, the raw materials are easily obtained, the cost is low, the effect is quick, and the cure rate is high, so it is a medicine for treating chronic colitis worthy of popularization.

The invention provides a compound enteritis capsule. It is characterized by simple treatment, convenient usage and functions of treating bacillary dysentery, acute and chronic enteritis. It makes use of the anti-biotic effect for bacillus coli and Bacillus dysenteriae of furazolidone, acts on intestine smooth muscle by using chlorhydric acid diphenoxylate, gets rid of crawl reflection of partial mucosa to reduce crawl by inhibiting intestine mucosa receptor, and increases intestine wall stage contraction and promotes water back-absorption in the intestine. The atropine sulfate can relieve intestine smooth muscle spasm and inhibit glandular secretion. The capsule comprises five chemical medicine, it can shorten the treating period for bacillary dysentery and acute enteritis, increase cure rate for various chronic colitis, and reduce pain for patient during injection, intravenous drip, bowel lavage and taking traditional medicine.

The present invention provides a powder pharmaceutical formulations for treating infantile diarrhea which overcomes weak pocket of other medicament for treating the disease. The powder pharmaceutical formulation is prepared by raw materials as follows: biofermin 0.1-1 g, compound diphenoxylate 0.25-2.5 mg, acetylsalicylic acid 0.3-0.15 g, chlorphenamine 0.04-0.2 mg and hydrochlorothiazidum tablet 1-5 mg, the above medicine are grinded to dead small, then are measured and packed for obtaining the powder pharmaceutical formulation. The powder pharmaceutical formulation for treating infantile diarrhea is used about twenty years and is consulted by patients 10000 times, wherein, males 5500 times, females 4500 times, curative rate 98% and efficiency rate 100%.

The invention relates to an application of fulvic acid sodium in preparing drugs for treating diarrhea. Research discovers that the fulvic acid sodium in the invention has low toxicity, can restrain the gastrointestinal motility of a normal mice, can cooperate with reinforced compound diphenoxylate to restrain the gastrointestinal motility of the mice, can obviously improve the physical sign of a mice suffering splenasthenic diarrhea caused by rheum officinale, and restrain the gastrointestinal motility of the mice suffering diarrhea, thus treating the diarrhea; and the research shows that the fulvic acid sodium has obvious effect of treating the diarrhea.

The invention relates to a drug for treating mink digestive tract diseases and belongs to the technical field of drugs for veterinary use. The drug is prepared from 10 parts by weight of gentamycin, 7-8 parts by weight of diphenoxylate, 8-10 parts by weight of radix astragali, 8-10 parts by weight of wrinkled giant hyssop, 5-6 parts by weight of radix bupleuri and the balance glucose. Individual use or combined use of radix astragali, wrinkled giant hyssop and radix bupleuri does not produce effects of treating mink digestive tract diseases but through combination with gentamycin, the mixed drug has a mink digestive tract disease cure rate of 73.5% and has curative effects obviously higher than effects of colistin sulfate. Through further use of a small amount of resveratrol and tetramethylpyrazine, a drug having a higher mink digestive tract disease cure rate is obtained.

The invention discloses a dendrobium officinale mixture. The dendrobium officinale mixture is prepared from the following traditional Chinese medicinal materials serving as raw materials in parts by weight: 10 to 12 parts of dendrobium officinale, 15 to 25 parts of raw atractylodis macrocephalae rhizome, 10 to 20 parts of radix scrophulariae, 10 to 20 parts of radix ophiopogonis, and 10 to 20 parts of raw radix rehmanniae. The dendrobium officinale mixture has the effects of increasing fluid, moistening dryness, nourishing yin, clearing heat, strengthening spleen and tonifying qi, and is used for constipation and the diseases that the defecating frequency is reduced, the excrement amount is little and hard in texture, a pleasant feeling disappears after defecating, and the defecating time or the defecating interval time is prolonged. In order to prove a good effect of the dendrobium officinale mixture to the constipation better, the effect of the mixture to a mouse with the constipation induced by compound diphenoxylate is investigated through an animal experiment; the effect shows that the mixture can promote the pushing of small intestines of the mouse with the constipation, promote defecation, protect intestinal mucosa and improve serum SOD.

The invention discloses a western medicine compound pharmaceutic preparation for treating diphtheritic enteritis. A Chinese medicine preparation comprises, by weight, 2-8 parts of dragon bones, 5-15 parts of fructus chebulae, 2-8 parts of nutmeg, 1-9 parts of honey-fried licorice roots, 5-15 parts of red halloysite, 5-13 parts of dogwood, 2-9 parts of szechwan Chinaberry fruits, 5-15 parts of rhizoma alismatis, 5-15 parts of elecampane and 1-9 parts of coptis chinensis. The western medicine preparation comprises, by weight, 0.1-0.5 part of diphenoxylate, 0.1-0.5 part of atropine sulphate, 0.8-1.2 parts of pectinesterase and 0.01-0.08 part of medicinal magnesium chloride. In the Chinese medicine preparation, the added components have the effects of warming the middle and benefiting qi, invigorating spleen and removing dampness and the like. The added western medicine preparation is obvious in sterilization effect, contributes to growth of an intestinal tract normal flora, and has an obvious curative effect on the diphtheritic enteritis, and the effect is quick.

The invention discloses a wear-resistant, anti-oxidation and anti-seepage photoelectric hybrid cable. The cable comprises an outer protection layer, a hybrid cable core and a ratproof layer. The outer protective layer is prepared from the following components in parts by weight: 18 to 21 parts of linear low-density polyethylene, 3.1 to 4.6 parts of chlorinated paraffin-52, 1.3 to 2.2 parts of polyether modified silicone oil, 6 to 9 parts of barium sulfate, 3 to 6 parts of high-abrasion-resistance carbon black, 1 to 3 parts of 2, 6-di-tert-butyl-4-methylphenol and 4 to 5 parts of calcium carbonate. The ratproof layer is prepared from the following components in parts by weight: 5 to 7 parts of barium sulfate, 6 to 9 parts of diphenoxylate, 5 to 10 parts of phthalate, 3 to 5 parts of polyvinyl alcohol, 1.8 to 2.3 parts of mint extract, 10 to 13 parts of capsaicin and 4 to 6 parts of ethanol. The photoelectric hybrid cable prepared from the raw materials is good in mechanical properties, long in service life and capable of effectively preventing rats.

The invention discloses a medicinal preparation used for protecting the livestock and poultry from diarrhea, which comprises the following raw materials by weight ratio: 1-20 parts of Radix Astragali, 1-20 parts of bighead atractylodes rhizome, 1-20 parts of licorice, 2-40 parts of white peony root, 20-150 parts of Limonite, 20-150 parts of red halloysite, 2-20 parts of pomegranate rind, 20-100 parts of alum, 3-30 parts of radix bupleuri, 4-10 parts of cimicifuga foetida, 1-20 parts of coptis and 0-3 parts of diphenoxylate. The components of the medicinal preparation are direct and mutual synergism, and has efficacy of supplementing the center and boosting qi, lifting up Yang and depression, antidarrhea with astringent, inhibiting smooth muscle spasm of gastrointestinal tract and alleviating peristaltic of gastrointestinal tract, and is capable of rapidly recovering the functions of gastrointestinal tract, thereby, the medicinal preparation has an obvious function of weight increasing.

The invention relates to a method for detecting diphenoxylate in a biological sample by liquid chromatography-tandem mass spectrometry for criminal investigation. The method comprises the following steps: (I) extracting diphenoxylate from the biological sample; and (II) detecting diphenoxylate extracted in the step (I) by a liquid chromatography-tandem mass spectrometry instrument. The method provided by the invention improves the sensitivity of the detection of diphenoxylate in the biological sample to be detected, and reduces the degree of detection difficulty of diphenoxylate in the biological sample to be detected.

The invention provides a pharmaceutical composition for treating colitis, and relates to the technical field of disease treatment. The pharmaceutical composition for treating colitis comprises the following pharmaceutical compositions: compound endothelium corneum gigeriae galli tablets, oryzanol tablets, medroxyprogesterone acetate tablets, compound diphenoxylate tablets and prednisone acetate tablets, wherein the pharmaceutical composition is taken three times a day, four compound endothelium corneum gigeriae galli tablets are taken each time, three oryzanol tablets are taken each time, three medroxyprogesterone acetate tablets are taken each time, two compound diphenoxylate tablets are taken each time, and one prednisone acetate tablet is taken each time. According to the invention, thepharmaceutical composition is used for treating colitis patients, so that the pain of the colitis patients is effectively relieved, the treatment effect of the colitis patients is obvious, the effectis quick, the treatment period is short, and meanwhile, the pharmaceutical composition for treatment is relatively cheap and relatively convenient to obtain.

The invention discloses functional-oligosaccharide-containing saccharose-free hawthorn coils, a preparation method therefor and application of the functional-oligosaccharide-containing saccharose-free hawthorn coils. In view of the current situation that the traditional hawthorn coils are too high in saccharose content, functional oligosaccharides are selected or are compounded with xylitol so as to replace saccharose, and the functional-oligosaccharide-containing saccharose-free hawthorn coils are prepared according to production process flows of the traditional hawthorn coils. The hawthorn coils disclosed by the invention have the functions that constipation and obesity preventing effects of the hawthorn coils are surveyed by taking diphenoxylate-hydrochloride-induced mouse constipation models and high-fat high-fructose feed induced mouse obesity models, and the action of improving defecation parameters of constipation mice and regulating lipid metabolism of obese mice is more remarkable (P is smaller than 0.05). In summary, the hawthorn coils provided by the invention are saccharose-free, are suitable for being properly eaten by people suffering from hyperglycemia, hyperlipemia and hypertension and have the functions of preventing constipation and obesity.

The invention relates to a medicine, particularly a traditional Chinese medicine composition preventing diarrhea. The composition includes a traditional Chinese medicine composition prepared by adopting 6-15 g of medicine terminalia fruit, 6-15 g of Chinese angelica, 6-15 g of radix aucklandiae and 6-15 g of debark peony root as raw materials and decocting the raw materials with water, and drying and crushing a decoction product, and a western medicine composition including 0.1-0.2 g of trimethoprim, 0.4-1 g of metronidazole, 0.05-0.3 g of isoniazide, 0.25-0.5 mg of diphenoxylate and 10-20 mg of vitamin B6. The weight of the western medicine composition is 1-80% of the weight of the traditional Chinese medicine composition preventing diarrhea. The traditional Chinese medicine composition preventing diarrhea is mainly used for treating chronic diarrhoea caused by various reasons. The effective rate is 98%, the curative rate is 80% or above, toxic and side effects are few and the traditional Chinese medicine composition preventing diarrhea is convenient to take.