149 results about "Cimetidine" patented technology

The invention discloses a waste gas treatment and methyl mercaptan recycling process in cimetidine and ranitidine production. The waste gas treatment and methyl mercaptan recycling process comprises the following steps: (1) introducing waste gas in the production process of cimetidine and ranitidine into a washing tank, controlling pressure to 0.2-0.3MPa, removing volatile substances which are low in boiling point and easily soluble in water in the waste gas; (2) introducing the waste gas subjected to washing treatment into an alkaline washing tank, controlling pressure to 0.2-0.3MPa, removing volatile substances which are insoluble in water and soluble in alkaline by alkaline liquor in the alkaline washing tank; (3) introducing the waste gas subjected to the alkaline washing into a three-stage absorbing device, removing methyl mercaptan in the waste gas to generate sodium thiomethoxide; and (4) introducing the waste gas subjected to the three stages of absorption into a hydrogen peroxide falling film absorbing tower for performing oxidation treatment, and then discharging. According to the waste gas treatment and methyl mercaptan recycling process, useful chemical raw materials in the waste gas are recycled on the basis of solving the problem of waste gas emission, and thus the waste gas is prevented from being discharged, the economic benefit is increased, a new value is created, and the recycling economy is realized. The waste gas treatment and methyl mercaptan recycling process is good in application prospect.

The invention relates to a chewing gum for preventing and treating oral ulcer resulted from chemotherapy and a preparation method of the chewing gum. The chewing gum comprises chewing gum ingredients and medicaments for preventing and treating oral ulcer; every 100 grams of chewing gum for preventing and treating oral ulcer comprise the following medicaments for preventing and treating oral ulcer by weight: 5mg-10mg of recombinant human granulocyte colony-stimulating factors, 5mg-10mg of folic acid, 5mg-10mg of metronidazole, 20mg-50mg of lidocaine, 5mg-20mg of cimetidine, 2.5mg-10mg of vitamin B2, and the balance being chewing gum ingredients. The chewing gum ingredients comprise the following components in percentage by weight: 25%-30% of edible gum base, 20%-25% of malt syrup, 35%-45% of xylitol and 10%-20% of sorbitol. The chewing gum disclosed by the invention can be used for effectively preventing and treating oral ulcer resulted from different disease causes after chemotherapy, further can be used for reducing stimulus of medicaments to gastrointestinal tract, reducing adverse reactions and increasing safety. Moreover, the chewing gum is good in mouth-feel and convenient to take.

The invention provides a cimetidine sodium chloride injection production method capable of preventing impurities from exceeding the standard, belongs to the technical field of medicines and mainly solves the problem that impurities in finished cimetidine sodium chloride injection products in the prior art exceed the standard. The method is characterized by comprising the three following steps: 1)concentrated preparation; 2) diluted preparation; 3) sterilization. The method specifically comprises the following steps: injecting injection water into a concentrated preparation tank, putting 2 kgof cimetidine and 9 kg of sodium chloride, performing stirring, starting a circulating pump in a diluted preparation tank, circulating a solution by a fine filter provided with a 0.45 mu m polyether sulfone filter element, adjusting the pH by a hydrochloric acid solution with concentration being 1 mol / L, finally, circularly sending the solution into a filling procedure after the solution passes through the fine filter provided with the 0.45 mu m polyether sulfone filter element, putting the solution in a non-PVC co-extrusion infusion bag according to the dosage, setting specific control sterilization parameters in a high-temperature superheated water shower manner during sterilization, and performing lamp inspection and packaging after sterilization to obtain the cimetidine sodium chlorideinjection.

The invention provides cimetidine composition chewable tablets and a preparation method thereof and relates to the technical field of medicines and medical production. The cimetidine composition chewable tablets comprise cimetidine, starch and cane sugar, the defects of common chewable tablets are overcome by virtue of the tablets disclosed by the invention, the types and amount of auxiliary materials in the cimetidine chewable tablets are reduced, and the pharmaceutical preparation is excellent in performance, high in bioavailability, high in stability and high in patient acceptance, does not have a sense of gravel and has important clinical application value.