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Drug for treating mink digestive tract diseases

A technology for digestive tract diseases and drugs, applied in the direction of digestive system, drug combination, active ingredients of hydroxyl compounds, etc., can solve problems such as strong infectivity, increased mortality, and disruption of normal microbiota balance

Inactive Publication Date: 2014-11-05
山东省动物疫病预防与控制中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since Escherichia coli diseases are mostly spontaneous infection and highly contagious, and the beneficial microorganisms in the digestive tract are also inhibited or killed during the treatment process, the balance of the normal microbiota is disrupted, so it cannot be cured for a long time
In addition, many stress factors lead to a sharp exacerbation of the disease, which greatly increases the mortality rate of the disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Get gentamicin 10g, diphenoxylate 7g, Radix Astragali 8g, Huoxiang 10g, Bupleurum 5g and glucose 60g and mix uniformly, grind into powder, obtain powder; drug.

Embodiment 2

[0053] Mix 10g of gentamicin, 8g of diphenoxylate, 5g of astragalus polysaccharide, 4g of Huoxiang water extract, 3g of saikosaponin, 6g of resveratrol, 5g of tetramethylpyrazine and 59g of glucose, and grind them into powder , to get a powder; the powder is the medicine for treating mink digestive tract diseases of the present invention.

Embodiment 3

[0055] Take 10g of Astragalus membranaceus, 8g of Huoxiang, 6g of Bupleuri and add water to make decoction, then concentrate and dry the decoction, then mix with 10g of gentamicin, 8g of diphenoxylate and 58g of glucose, and grind it into powder Shape, get powder; This powder is the medicine for the treatment of mink digestive tract disease of the present invention.

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Abstract

The invention relates to a drug for treating mink digestive tract diseases and belongs to the technical field of drugs for veterinary use. The drug is prepared from 10 parts by weight of gentamycin, 7-8 parts by weight of diphenoxylate, 8-10 parts by weight of radix astragali, 8-10 parts by weight of wrinkled giant hyssop, 5-6 parts by weight of radix bupleuri and the balance glucose. Individual use or combined use of radix astragali, wrinkled giant hyssop and radix bupleuri does not produce effects of treating mink digestive tract diseases but through combination with gentamycin, the mixed drug has a mink digestive tract disease cure rate of 73.5% and has curative effects obviously higher than effects of colistin sulfate. Through further use of a small amount of resveratrol and tetramethylpyrazine, a drug having a higher mink digestive tract disease cure rate is obtained.

Description

technical field [0001] The invention relates to a medicine for treating mink digestive tract diseases, belonging to the technical field of veterinary medicine. Background technique [0002] In the process of mink breeding, colibacillosis is a common digestive tract disease of minks; colibacillosis is an acute disease, and acutely ill minks die within 2-3 days. Because E. coli diseases are mostly spontaneous infection and highly contagious, and the beneficial microorganisms in the digestive tract are also suppressed or killed during the treatment process, the balance of the normal microbiota is disrupted, so it cannot be cured for a long time. In addition, many stress factors lead to a sharp exacerbation of the disease, which greatly increases the mortality rate of the disease. [0003] Gentamicin is an aminoglycoside antibiotic, which is suitable for Pseudomonas aeruginosa, Proteus (indole positive and negative), Escherichia coli, Klebsiella, Enterobacter, Serratia, Citro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/532A61P1/00A61P31/04A61K31/7036A61K31/451A61K31/05A61K31/4965A61K31/715A61K31/7004
Inventor 王贵升王金宝田夫林张进林李玉杰刘少宁张月徐鸿
Owner 山东省动物疫病预防与控制中心
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