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Antidiarrheal pharmaceutical composition

A composition and drug technology, applied in the directions of drug combination, active ingredients of heterocyclic compounds, pharmaceutical formulations, etc., can solve the problems of increasing segmental contraction, easy to increase complications, large physical exertion, etc., and achieve pain relief and clinical relief. Symptoms, low-cost effects

Inactive Publication Date: 2008-09-10
韩耀云
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] There are many antidiarrheal drugs now, but the antidiarrheal is slow, and the diarrhea will consume a lot of energy after a long time, and it is not easy to recover, and it is easy to increase complications, such as dehydration, which brings pain to the patient; existing drugs such as compound diphenoxylate, It directly acts on the intestinal smooth muscle, by inhibiting the intestinal mucosal receptors, eliminating the peristaltic reflex of the local mucosa and weakening the peristalsis, and at the same time increasing the segmental contraction of the intestines, thereby prolonging the contact between the intestinal contents and the intestinal mucosa, and promoting the return of intestinal water Absorption; used for acute and chronic functional diarrhea and chronic enteritis, but the curative effect is slow

Method used

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  • Antidiarrheal pharmaceutical composition
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Examples

Experimental program
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Effect test

Embodiment 1

[0027] Example 1: 2.5 parts of compound diphenoxylate, 5 parts of prednisone, and 10 parts of hydrochlorothiazide.

Embodiment 2

[0028] Example 2: 1.5 parts of compound diphenoxylate, 3 parts of prednisone, and 5 parts of hydrochlorothiazide.

Embodiment 3

[0029] Example 3: 3 parts of compound diphenoxylate, 6 parts of prednisone, and 14 parts of hydrochlorothiazide.

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PUM

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Abstract

The invention discloses a composition of an antidiarrheal agent, which consists of the following weight portions of ingredients: 1.5-3 portions of compound diphenoxylate, 2.5-6 portions of prednisone and 5-15 portions of hydrochlorothiazide. The composition of the antidiarrheal agent has clear curative effect, good efficacy, rapid disappearance of diarrhea; diuresis effect of the hydrochlorothiazide is utilized to absorb water and reduce intestinal water, and the anti-inflammatory and anti-infection functions of prednisone are applied to mitigate clinic sympton, the cooperation of these three medicines accelerates the antidiarrheal speed and relieves the pain of the sufferers. The composition of the antidiarrheal agent has low cost, which is lower than Xieliting by 5-6 times.

Description

technical field [0001] The invention relates to an antidiarrheal medicine, in particular to a composition of antidiarrheal medicine. Background technique [0002] There are many antidiarrheal drugs now, but the antidiarrheal is slow, and the time of diarrhea is long, the physical exertion is great, it is not easy to recover, and it is easy to increase complications, such as dehydration, which brings pain to the patient; existing drugs such as compound diphenoxylate, It directly acts on the intestinal smooth muscle, by inhibiting the intestinal mucosal receptors, eliminating the peristaltic reflex of the local mucosa and weakening the peristalsis, and at the same time increasing the segmental contraction of the intestines, thereby prolonging the contact between the intestinal contents and the intestinal mucosa, and promoting the return of intestinal water Absorption; for acute and chronic functional diarrhea and chronic enteritis, but the effect is slow. Contents of the inv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/445A61K31/573A61K31/5415A61P1/12
Inventor 韩耀云
Owner 韩耀云
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