284 results about "Atractylodes lancea" patented technology

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating constipation and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from betel nut, szechwan chinaberry fruit, bighead atractylodes rhizome, bunge cherry seed, vinegar-processed curcuma zedoary, immature bitter orange, officinal magnolia bark, coix seed and Chinese angelica. The traditional Chinese medicine composition disclosed by the invention has the effects of promoting qi circulation, removing stagnation, tonifying spleen, clearing damp, relaxing bowel, nourishing blood and promoting blood circulation, is mainly used for treating qi stagnation type, spleen deficiency type or mixed type constipation, and is particularly suitable for functional constipation, senile constipation or postpartum constipation with the syndromes. Besides, the traditional Chinese medicine composition is deeply optimized by utilizing a modern preparation process on the basis of a traditional Chinese medicine formula, the preparation method is simple, and the traditional Chinese medicine composition can be prepared into various dosage forms such as granules, tablets, oral liquid or capsules.

The invention relates to the field of plant extracts and daily chemicals, in particular to preparation and application of a penthorum chinense pursh leaf and stem extract with acne removing and oxidation resisting effects. The preparation method of the extract comprises the following steps: taking a penthorum chinense leaf and stem dry product, carrying out heating extraction or ultrasonic crushing extraction by taking water as a solvent, carrying out purification and impurity removal or filtration and impurity removal by using a chitosan quaternary ammonium salt-sodium alginate combined biological flocculation method, taking supernate, carrying out vacuum concentration, and carrying out spray drying, so as to obtain the penthorum chinense leaf and stem extract. The content of the quercitrin in the index component is more than or equal to 16mg / g. The effect of the invention is extracted from the characteristic medicinal and edible plant penthorum chinense pursh in China, is high in safety, has obvious acne-removing and anti-oxidation effects, and is a novel functional cosmetic plant raw material with excellent application prospect.

The invention discloses a freckle-removing mask preparation method and equipment, and relates to the technical field of beauty and skincare, the freckle-removing mask preparation method comprises the following steps: S1, selecting and purchasing: selecting and purchasing high-quality formula raw materials; s2, inspection: inspecting the purchased raw materials; s3, pretreatment: washing part of the Chinese herbal medicine raw materials with clear water, and drying the Chinese herbal medicine raw materials; s4, pre-processing: crushing and grinding the prepared raw materials, and screening and filtering to remove impurities; the facial mask is prepared from ligusticum, radix angelicae, radix asparagi, astragalus membranaceus, bighead atractylodes rhizome, silkworm larva, bletilla striata, radix paeoniae alba, poria cocos, salvia miltiorrhiza, ampelopsis japonica, tribulus terrestris, pseudo-ginseng, rose, ginseng, honeysuckle, pearl and other blood-activating and repairing components, so that the effect of eliminating laser spots and heavy metal residual spots is improved, and meanwhile, the whitening degree and the skin glossiness are improved; the ductility, the moistening property and the permeability are improved, the stickiness and the greasiness are reduced, the moisturizing and water locking durability is improved through moisturizing factors of various components, and the spot fading effect is improved.

The invention relates to the technical field of gene engineering, in particular to an atractylodes macrocephala terpene synthase gene AmTPS9 and a product coded by the same and application of the gene AmTPS9. The gene AmTPS9 has one of the following nucleotide sequences: (1) a nucleotide sequence as shown in SEQ ID NO.1; and (2) a nucleotide sequence which is obtained by substituting, deleting or adding one or more nucleotides to the nucleotide sequence as shown in SEQ ID NO.1 and expresses protein with the same function. According to the invention, a coding gene of an atractylodes macrocephala terpene synthase gene (AmTPS) is cloned from the rhizome of the atractylodes macrocephala, and the synthase can be applied to a pathway prepared by taking farnesyl pyrophosphate (FPP) as a substrate. By utilizing the gene provided by the invention, the content of terpenoids in bighead atractylodes rhizome can be increased through a genetic engineering technology.

The application discloses a ganoderma lucidum compound composition for improving immunity, which is prepared from ganoderma lucidum, ginseng, astragalus, licorice, cistanche, schisandra chinensis, cyperus rotundus, pericarpium citri reticulatae viride, melia toosendan, radix codonopsis, atractylodes, dioscorea, chuanxiong, angelica sinensis, radix rehmanniae preparatae, ligustrum lucidum, medlar, pinellia ternata, poria cocos and white mustard seed, and can be used for treating low immunity caused by heart-lung qi deficiency by supplementing heart qi, tonifying lung and spleen, dispersing liver and resolving stagnation, and activating blood circulation.

The invention belongs to the field of wash supplies, and provides a composition with functions of controlling oil, inhibiting bacteria, relieving itching and repairing ultraviolet damage and a facial cleanser. The composition is prepared from hydrolyzed keratin, recombinant collagen, zinc acetate, a rhizoma atractylodis macrocephalae extract, zingiber officinale roscoe essential oil and a fructus cnidii extract, and the mass ratio of the hydrolyzed keratin to the recombinant collagen to the zinc acetate to the rhizoma atractylodis macrocephalae extract to the zingiber officinale roscoe essential oil to the fructus cnidii extract is (3-3.2): (3-3.2): (1-1.2): (2-2.2): (2-2.2): (2-2.2). The facial cleanser contains the composition, and the mass fraction of the composition in the facial cleanser is 0.1%-5.0%. Experiments prove that the composition and the facial cleanser have good effects in the aspects of inhibiting skin sebum secretion, inhibiting bacteria, inhibiting eczema, inhibiting allergic rash, relieving itching, repairing ultraviolet damage and the like, and the problem that the comprehensive performance of the existing composition for facial skin and the related facial cleanser is not satisfactory can be solved.

The invention discloses a preparation method of anti-aging whitening skin cream based on traditional Chinese medicine exosome extraction, and relates to the technical field of cosmetics. Comprising the following steps: (1) raw material compatibility and pretreatment: taking 1-8 parts by mass of abelmoschus manihot exosome, 1-8 parts by mass of bighead atractylodes rhizome exosome, 1-8 parts by mass of bletilla striata exosome, 1-8 parts by mass of radix angelicae exosome, 1-8 parts by mass of white poria cocos exosome, 1-8 parts by mass of radix paeoniae alba exosome, 1-8 parts by mass of lily exosome, 1-8 parts by mass of silkworm larva exosome, 1-8 parts by mass of white asarum exosome and 1-8 parts by mass of cordyceps sinensis exosome; according to the skin care product disclosed by the invention, the exosome system of twelve traditional Chinese medicinal materials is applied to the field of skin care products for the first time; a complete traditional Chinese medicine exosome extraction, identification and preparation technology system is established; the exosome is used as a natural nano-carrier, so that the skin permeability of active ingredients is remarkably improved; based on the theory of complementing color with color in traditional Chinese medicine, traditional Chinese medicinal materials with white character heads are carefully selected; the exosomes of the medicinal materials have a synergistic effect, so that multi-target skin metabolism regulation is realized.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine electuary for intestinal injury caused by radiotherapy and chemotherapy and a preparation method of the traditional Chinese medicine electuary. According to the composition principle of monarch, minister, assistant and guide of a traditional Chinese medicine prescription, the traditional Chinese medicine electuary is prepared by taking radix astragali preparata as a monarch drug, taking radix codonopsis and rhizoma polygonati as minister drugs, and taking poria cocos, bran-fried rhizoma atractylodis macrocephalae, hairyvein agrimony, Chinese pulsatilla root, rhizoma bletillae and pinellia ternate as assistant drugs, and taking pericarpium citri reticulatae, vinegar-processed curcuma zedoary, pseudo-ginseng and musk as assistant drugs through scientific compatibility and a preparation process. The intestinal function can be adjusted, and the intestinal injury symptom caused by radiotherapy and chemotherapy is improved.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a turbidity-dissolving and lipid-lowering composition and a preparation method thereof.The composition comprises 80-130 parts of polygonum cuspidatum, 50-90 parts of fried semen cassiae, 100-140 parts of hawthorn, 50-90 parts of rhizoma alismatis, 10-60 parts of rhizoma atractylodis macrocephalae fried with bran and 50-90 parts of rhizoma wenyujin concisum. The composition disclosed by the invention has the effects of eliminating phlegm, dissolving turbidity, promoting blood circulation to remove blood stasis, invigorating stomach and promoting diuresis, can be used for treating hyperlipidemia, hyperviscosity and arteriosclerotic cardia-cerebrovascular diseases, and has a very good application prospect.

The invention discloses a fermented traditional Chinese medicine compound capable of nourishing qi and blood and resisting aging, which is a composition of a fermented product and an edible carrier thereof, wherein the fermented product is obtained by carrying out composite enzymolysis treatment on traditional Chinese medicinal materials with the effects of tonifying qi, enriching blood and resisting aging and then carrying out composite strain fermentation on the treated traditional Chinese medicinal materials. Wherein the traditional Chinese medicinal materials at least comprise qi-tonifying traditional Chinese medicinal materials selected from ginseng, codonopsis pilosula, astragalus membranaceus, radix pseudostellariae, bighead atractylodes rhizome, poria cocos and liquorice; the blood-enriching traditional Chinese medicinal materials are selected from angelica sinensis, prepared rehmannia roots, radix paeoniae alba, donkey-hide gelatin, longan aril and mulberries; the anti-aging traditional Chinese medicinal materials are selected from fructus lycii, glossy privet fruit, dogwood, polygonum multiflorum, polygonatum kingianum, ginseng and acanthopanax senticosus.

The invention discloses a Chinese herbal medicine immunopotentiator for special fur economic animals as well as a preparation method and application of the Chinese herbal medicine immunopotentiator. Belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 2-4 parts of echinacea purpurea, 2-4 parts of bighead atractylodes rhizome, 2-4 parts of Chinese yam, 1-2 parts of medlar and 1-2 parts of codonopsis pilosula. The raw material medicines are subjected to crushing, burdening, water boiling extraction, concentration and packaging to prepare the medicine. The Chinese herbal medicine immunopotentiator for the special fur economic animals has good effects of enhancing the disease resistance and disease prevention capability of racoon dog and improving the immunity.

The invention relates to a formula and a preparation method of compound desert cistanche granules, the compound desert cistanche granules are prepared by adding flavor on the basis of Qingzheng dialectical record yang-warming soup, the raw materials comprise desert cistanche, bighead atractylodes rhizome, monkshood, Chinese angelica, cynomorium songaricum, fried semen raphani and perillaseed, and the total weight of a single bag is 7g. The production process comprises the key steps of pretreatment of medicinal materials, independent first decoction of radix aconiti carmichaeli for detoxification, extraction of semen raphani and perillaseed volatile oil, inclusion of beta-cyclodextrin, combined decoction and concentration of all the medicinal materials, dry granulation and the like, and the technical effects that granules are instantly dissolved within 45 + / -5 seconds and the transfer rate of crude drugs is 91.2% are achieved by optimizing the proportion of auxiliary materials and process parameters. The quality of the finished product meets the requirements of Chinese Pharmacopoeia, the content of aconitine is less than or equal to 0.02%, the total number of microbial limit aerobic bacteria is less than or equal to 100 CFU / g, the problems that a traditional compound cistanche deserticola preparation is slow in dissolution speed, unstable in toxicity control and non-standard in production process are solved, and the method is suitable for large-scale industrial production.

The present application provides a kind of traditional Chinese medicine composition for weight loss, hypolipidemic and its preparation method and use.The traditional Chinese medicine composition is made of the following raw materials by weight parts: Bai Zhi 10-20 parts, Dang Shen 10-20 parts, Tu Fu Ling 15-25 parts, Dan Shen 15-25 parts, Rou Fu Zhi Shu 5-15 parts, Rou Fu Yi Ren 15-25 parts, Chen Pi 10-20 parts, Fa Ban Xia 10-20 parts, Shan Zha 5-15 parts, Huang Lian Pian 15-25 parts, Chao Jue Ming Zi 15-25 parts, Rou Fu Cang Zhu 5-15 parts, Gan Jiang 5-15 parts, Xiao Tong Cao 2-8 parts.The traditional Chinese medicine composition of the present application is based on the theory of TCM syndrome differentiation, and is reasonable in prescription compatibility, with significant effects of weight loss and lipid-lowering.

The invention discloses a medicinal composition for strengthening body resistance and nourishing liver as well as a preparation method and application thereof. The preparation method of the composition comprises the following steps: weighing the 15 medicinal materials according to the formula amount, crushing the turtle shell, decocting for about half an hour, then adding the rest medicinal materials, decocting, filtering, and concentrating the water decoction to 1 / 3-1 / 5 of the water addition amount, thereby obtaining the traditional Chinese medicine composition. The healthy-energy-strengthening and liver-nourishing soup has the effects of inducing diuresis, nourishing the liver, relieving ascites due to cirrhosis and the like, can relieve the symptoms of patients suffering from cirrhosis due to deficiency of healthy energy, blood stasis and qi stagnation and water retention, and can be used for treating cirrhosis diseases. The prepared decoction is fast in oral administration absorption and fast in drug effect exertion. And the product has high safety and no adverse reaction.

The application discloses a method for establishing a gynecological menstruation-regulating tablet fingerprint spectrum by using a high-performance liquid chromatography technology and application, by using the method, a good fingerprint spectrum is obtained, and the chromatographic peak is comprehensive, 12 fingerprint peaks are confirmed, wherein, corresponding attribution peaks of angelica sinensis, fried atractylodes macrocephala koidz, vinegar corydalis and chuanxiong are all in the gynecological menstruation-regulating tablet, and the angelica sinensis, fried atractylodes macrocephala koidz and vinegar corydalis all have exclusive peaks. By comparing with the reference substance, and combining with ultraviolet absorption spectrum characteristics, characteristic peaks of five chemical components, i.e., chlorogenic acid, ferulic acid, chuanxiongolide I, ligusticum lactone and butenyl phthalide are identified. The application further discloses a reference fingerprint spectrum of the gynecological menstruation-regulating tablet obtained by using the method, the gynecological menstruation-regulating tablet fingerprint spectrum detection method and the obtained reference fingerprint spectrum can objectively evaluate the overall quality of the gynecological menstruation-regulating tablet, and provide a research basis for quality control of the gynecological menstruation-regulating tablet.

The invention relates to the technical field of duck breeding, in particular to a traditional Chinese medicine composition and application thereof in treating riemerella anatipestifer. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3-12 parts of rhizoma coptidis, 3-12 parts of cortex phellodendri, 5-20 parts of cortex fraxini, 8-30 parts of dandelion, 3-12 parts of radix saposhnikoviae, 5-20 parts of fried fructus aurantii, 8-30 parts of fried rhizoma atractylodis macrocephalae and 3-12 parts of liquorice. The novel traditional Chinese medicine composition is obtained through research, the traditional Chinese medicine composition with a better treatment effect on riemerella anatipestifer disease is obtained through synergistic compatibility of all the components, and the traditional Chinese medicine composition has important application value.

The application belongs to the technical field of microbial application, and specifically discloses application of roseofungin Streptomyces roseofunginus in plant disease prevention and treatment. The application finds that after R&M synthesis genes in roseofungin Streptomyces roseofunginus are knocked out, the strain can still synthesize oxazolomycin A. Further finding is that oxazolomycin A shows good inhibitory effect on pepper Phytophthora capsici and Phytophthora sansomei, wherein the EC 50 value of pepper Phytophthora capsici PC35 is 2.95 μg / mL, and the EC 50 value of atractylodes Phytophthora sansomei AMPH-1 is 2.39 μg / mL. The oxazolomycin A prepared by the application can be developed into a biological pesticide that can effectively meet the agricultural development demand of "green ecology", and provides key biocontrol resource support for green prevention and control of plant diseases.

The present application relates to a kind of anti-non-small cell lung cancer for strengthening healthy qi and resolving stasis and preparation method thereof, strengthening healthy qi and resolving stasis is made from the following weight proportion of raw medicinal materials: Ficus pumila 2g~50g / portion, radix pseudostellariae 2g~50g / portion, poria cocos 2g~50g / portion, atractylodes 2g~50g / portion, radix scutellariae 2g~50g / portion, oldenlandia 2g~50g / portion, cat's paw grass 2g~50g / portion, giant knotweed 2g~50g / portion, curcuma zedoary 2g~50g / portion, oyster 2g~50g / portion, platycodon 2g~50g / portion, mountain bitterling 2g~50g / portion, half branch orchid 2g~50g / portion. By cell test and the construction NSCLC osimertin drug resistance animal model prove, strengthening healthy qi and resolving stasis of the present application can adjust tumor microenvironment (TME) and inhibit non-small cell lung cancer cell growth of osimertin drug resistance. Not only this, strengthening healthy qi and resolving stasis of the present application can also inhibit common non-small cell lung cancer cell growth. While clinical observation finds, strengthening healthy qi and resolving stasis of the present application can improve insomnia, skin rash, diarrhea and other symptoms of lung accumulation (lung cancer, lung nodule) patient, improve its quality of life.

The invention provides a composite antibiotic-replacing microcapsule preparation as well as a preparation method and application thereof. The composite antibiotic-replacing microcapsule preparation comprises a core material as well as an inner-layer wall material and an outer-layer wall material which are sequentially coated outside the core material, wherein the core material comprises a Chinese herbal medicine extract, plant essential oil and probiotics, the Chinese herbal medicine extract comprises forsythin, astragalus polysaccharide and atractylenolide III, the plant essential oil comprises origanum oil and cinnamyl aldehyde, and the probiotics comprise bacillus subtilis; the inner-layer wall material is prepared by crosslinking sodium alginate and calcium chloride, and the outer-layer wall material comprises chitosan. The traditional Chinese medicine composition has the characteristics of synergistic interaction, high stability and good intestinal tract targeting property, and can improve the resistance replacement effect.

This invention discloses a eucalyptane-type sesquiterpene dimer compound, its preparation method, and its applications, belonging to the field of pharmaceutical preparation technology. The six eucalyptane-type sesquiterpene dimers (compounds 1-6) disclosed in this invention are novel compounds with defined stereostructures and optically pure composition, exhibiting varying degrees of cytotoxic activity against HepG2, Hep3B, and Huh7 cells. Using sorafenib as a positive control, compounds 1, 5, and 6 showed stronger cytotoxic activity against HepG2 cells than the positive control sorafenib, compound 5 exhibited the strongest cytotoxic activity against Hep3B cells, and compounds 1, 4, 5, and 6 showed stronger cytotoxic activity against Huh7 cells than the positive control sorafenib. Therefore, compounds 1-6 disclosed in this invention have the potential to be developed into anti-hepatocellular carcinoma drugs, showing promising application prospects, and also provide important theoretical support for the further development of Atractylodes macrocephala medicinal plant resources.

The invention provides a traditional Chinese medicine composition for preventing and treating cattle hoof diseases as well as a preparation method and application thereof, and belongs to the technical field of veterinary traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 30 to 40 parts of honeysuckle flower, 15 to 20 parts of herba artemisiae scopariae, 20 to 25 parts of radix astragali seu hedysari, 12 to 18 parts of poria cocos, 10 to 15 parts of rhizoma atractylodis macrocephalae, 6 to 12 parts of radix angelicae sinensis, 4 to 8 parts of radix paeoniae rubra, 12 to 18 parts of rhizoma dioscoreae, 9 to 13 parts of fructus cnidii, 8 to 12 parts of radix achyranthis bidentatae and 5 to 10 parts of liquorice root. The traditional Chinese medicine composition is scientific in formula, has the effects of clearing away heat and toxic materials, eliminating dampness and astringing sores, tonifying qi and activating blood, relieving swelling and pain and strengthening tendons and bones through combination of the medicines, can effectively prevent and treat common hoof diseases such as foot rot, cattle laminitis and hoof abscess caused by factors such as acidosis, bacterial infection and downward flow of damp-heat, and has the advantages of remarkable curative effect, no medicine residue, high safety and the like.

The invention discloses a composition containing an astragalus extract as well as a preparation method and application of the composition. The composition comprises a carrier layer, a core functional layer, an assistant functional layer, a functional powder layer and a probiotic layer from inside to outside. According to the invention, monarch and ministerial drugs (astragalus membranaceus, codonopsis pilosula, bighead atractylodes rhizome and poria cocos) are taken as a core layer through a fluidized bed, adjuvant and conductant drugs (isatis root, dandelion and platycodon grandiflorum) are taken as a secondary layer, sequence batch layering is realized, and directional release can be realized.

The utility model provides a planting room for largehead atractylodes rhizome seedlings, relates to the technical field of auxiliary devices for planting the largehead atractylodes rhizome seedlings, and aims to solve the problem that the growth quality of the largehead atractylodes rhizome seedlings is influenced due to poor temperature control effect of the conventional planting room for the largehead atractylodes rhizome seedlings. Comprising a culture room, supporting legs are evenly distributed at the bottom of the culture room, an opening is formed in the culture room, a cover plate is hinged to the position of the opening, a culture frame is installed on the culture room, the culture frame is filled with soil, largehead atractylodes rhizome seedlings are planted in the soil, and a central processing unit is installed at the top of the culture room. A heating box is installed on the right side of the central processing unit, a plurality of sets of heating resistance wires are arranged in the heating box in a penetrating mode, a power source is installed on the top of the heating box, the heating resistance wires are connected with the power source through electric wires, an inlet pipe is arranged on the culture room, and the heating box is connected with the inlet pipe through an input pipe. And the central processing unit is connected with the power supply through a cable.

The invention provides an acupuncture medicine combined preparation for treating post-stroke limb spasm and a preparation method, and belongs to the technical field of medical products, the acupuncture medicine combined preparation comprises the following raw material medicines by weight: 8-12 parts of Chinese angelica, 8-12 parts of red sage root, 4-8 parts of raw frankincense, 4-8 parts of raw myrrh, 25-35 parts of Radix Astragali, 15-25 parts of Caulis Spatholobi, 10-14 parts of Radix Codonopsis, and 10-14 parts of Rhizoma Atractylodis Macrocephalae. The traditional Chinese medicine composition has the beneficial effects that a formula taking multiple medicinal materials such as angelica sinensis and salvia miltiorrhiza as cores is combined with an acupuncture scheme for use, so that the spasm score improvement rate and the limb movement function effective rate are improved, and the traditional Chinese medicine composition is remarkably superior to single use of traditional Chinese medicines, single use of acupuncture and natural recovery, and the synergistic superimposed curative effect of acupuncture and medicine is clearly realized; the traditional Chinese medicine composition can quickly relieve limb spasm symptoms after mild stroke, follows the traditional Chinese medicine syndrome differentiation and treatment principle, does not have obvious toxic and side effects such as gastrointestinal discomfort and drowsiness, is more suitable for long-term rehabilitation treatment of patients compared with conventional western medicine spasmodifiers, and is wider in applicable crowd.

This invention relates to a traditional Chinese medicine preparation for treating infectious bursal disease (IBD), its preparation method, and its application. The preparation comprises the following components: Astragalus membranaceus 45-50 parts, Rehmannia glutinosa 30-45 parts, Isatis indigotica 25-30 parts, Isatis tinctoria 25-30 parts, Gypsum fibrosum 10-45 parts, Lonicera japonica 10-20 parts, Forsythia suspensa 10-30 parts, Taraxacum mongolicum 10-20 parts, Atractylodes macrocephala 15-20 parts, Paeonia lactiflora 15-30 parts, Lilium brownii 15 parts, Anemarrhena asphodeloides 15 parts, and Glycyrrhiza uralensis 10-30 parts. The preparation is achieved through extraction and concentration processes and is effective in treating IBD in chickens caused by both traditional infectious bursal disease virus (IBDV) and novel variant infectious bursal disease virus (nvvIBDV). This medicine significantly improves the cure rate against both traditional and variant strains, showing a particularly significant advantage in treating variant strains.

The invention provides a rhizoma atractylodis macrocephalae continuous cropping obstacle retarding agent, and relates to the technical field of biological agent preparation, the rhizoma atractylodis macrocephalae continuous cropping obstacle retarding agent comprises the following components by mass: 14.5-30 parts of a complex microbial inoculant; and 2000 to 3000 parts of an organic fertilizer. The Atractylodes macrocephala continuous cropping obstacle retarding agent effectively retards Atractylodes macrocephala continuous cropping obstacles, and improves the quality and yield of the Atractylodes macrocephala continuous cropping.