The invention relates to a gel patch with heat clearing, swelling removing and pain stopping functions and a preparation method of the gel patch. According to the method, amur corktree barks, Chinesegoldthread rhizomes, medicinal rhubarb roots and rhizomes, raw gypsum, purslane herbs, herba siegesbeckiae, lobedleaf pharbitis seeds, fourstamen stephania roots, calabash shells, Indian bread exodermis, Chinese clematis roots and yanhusuo rhizomes are extracted by ethyl alcohol or water, extracts are dried to obtain powdery alcohol extracts or water extracts, or original medicinal materials are directly grinded into powder and screened to obtain fine medicinal powder, the powdery alcohol extracts, the water extracts and /or the fine medicinal powder, borneol, mirabilite and substrates are crosslinked to prepare the gel patch, and the substrates comprise polyoxyethylene hydrogenated castor oil, sodium polyacrylate, dihydroxyaluminum aminoacetate, tartaric acid, glycerin, povidone and oilyazone. The prepared gel patch can remarkably relieve arthritis and has good functions of clearing heat and removing swelling. Compared with a traditional preparation, the gel patch has the advantagesthat medicine using modes are diverse, drug loading capacity is high, moist maintenance performances are good, residues are omitted, gastrointestinal reaction is omitted, using and carrying are convenient, and compliance of a patient can be remarkably improved.