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Evodia rutaecarpa and ginger emplastrum and preparation method thereof

A technology of evodia rutaecarpa and plaster, applied in anti-inflammatory agents, pharmaceutical formulas, non-central analgesics, etc., can solve problems that no one has raised, and achieve the effect of peeling off without residue, easy to apply, and good appearance and shape

Active Publication Date: 2021-09-21
GUIZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, no one has proposed the research on the combination of Evodia rutaecarpa and ginger to prepare plasters

Method used

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  • Evodia rutaecarpa and ginger emplastrum and preparation method thereof
  • Evodia rutaecarpa and ginger emplastrum and preparation method thereof
  • Evodia rutaecarpa and ginger emplastrum and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Embodiment 1, a plaster of Evodia rutaecarpa and ginger. The raw materials of the plaster are: 2.6g of the extract stream extract of Evodia rutaecarpa and ginger, 0.06g of aluminum glycylate, 1.8g of glycerin, 0.1g of propylene glycol, 1g of sodium polyacrylate, and Parkin ethyl ester 0.03g, tartaric acid 0.04g, distilled water 1g and kaolin 1.2g.

[0046] The preparation method of the extract fluid extract of the evodia rutaecarpa and ginger is:

[0047] (1) Weigh Evodia rutaecarpa and ginger with a mass ratio of 1.8:1.1, put Evodia rutaecarpa and ginger into a 2000mL round bottom flask, add zeolite, heat and reflux on a heating mantle with 10 times the amount of 75% ethanol solution for 2 hours, and set aside to cool After 30 minutes, the cooled extract mixture was obtained;

[0048] (2) removing the solid residue by vacuum filtration of the cooled extract mixture to obtain the extract after suction filtration;

[0049] (3) Use a rotary evaporator to spin out the so...

Embodiment 2

[0055] Embodiment 2, a plaster of Evodia rutaecarpa and ginger. The raw materials of the plaster are: 3.4 g of extract fluid extract of Evodia rutaecarpa and ginger, 1 g of aluminum glyoxate, 2.6 g of glycerin, 0.5 g of propylene glycol, 1.5 g of sodium polyacrylate, and Parkin ethyl ester 0.07g, tartaric acid 0.08g, distilled water 1.4g and kaolin 1.8g.

[0056] The preparation method of the extract fluid extract of the evodia rutaecarpa and ginger is:

[0057] (1) Weigh Evodia rutaecarpa and ginger with a mass ratio of 2.2:0.9, put Evodia rutaecarpa and ginger into a 2000mL round bottom flask, add zeolite, heat and reflux on a heating mantle with 10 times the amount of 75% ethanol solution for 2 hours, and set aside to cool After 30 minutes, the cooled extract mixture was obtained;

[0058] (2) removing the solid residue by vacuum filtration of the cooled extract mixture to obtain the extract after suction filtration;

[0059] (3) Using a rotary evaporator to spin out the ...

Embodiment 3

[0065] Embodiment 3, a plaster of Evodia rutaecarpa and ginger. The raw materials of the plaster are: 2.8 g of the extract stream extract of Evodia rutaecarpa and ginger, 0.07 g of aluminum glycerol, 2 g of glycerin, 0.2 g of propylene glycol, 1.1 g of sodium polyacrylate, and Parkin ethyl ester 0.04g, tartaric acid 0.05g, distilled water 1.1g and kaolin 1.3g.

[0066] The preparation method of the extract fluid extract of the evodia rutaecarpa and ginger is:

[0067] (1) Weigh Evodia rutaecarpa and ginger with a mass ratio of 2:1, put Evodia rutaecarpa and ginger into a 2000mL round bottom flask, add zeolite, heat and reflux on a heating mantle with 10 times the amount of 75% ethanol solution for 2 hours, and set aside to cool After 30 minutes, the cooled extract mixture was obtained;

[0068] (2) removing the solid residue by vacuum filtration of the cooled extract mixture to obtain the extract after suction filtration;

[0069] (3) Use a rotary evaporator to spin out the ...

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Abstract

The invention discloses an evodia rutaecarpa and ginger emplastrum and a preparation method thereof. The evodia rutaecarpa and ginger emplastrum is prepared from the following raw material medicines in parts by weight: 2.6 to 3.4 parts of evodia rutaecarpa and ginger extract, 0.06 to 1 part of dihydroxyaluminum aminoacetate, 1.8 to 2.6 parts of glycerol, 0.1 to 0.5 part of propylene glycol, 1 to 1.5 parts of sodium polyacrylate, 0.03 to 0.07 part of ethylparaben, 0.04 to 0.08 part of tartaric acid, 1 to 1.4 parts of distilled water and 1.2 to 1.8 parts of kaolin. In the main medicines, the evodia rutaecarpa is compatible with the fresh ginger. The evodia rutaecarpa and the ginger are used together, and the ginger not only can restrain the drawness of the evodia rutaecarpa, but also can enhance the yang warming, cold dispelling, stomach harmonizing and adverse qi lowering effects of the evodia rutaecarpa. In the preparation process, stirring is easy, all phases are mutually fused, and the prepared paste is uniform in color, free of obvious particles, easy to coat, free of strip breaking and overflowing phenomena and excellent in product quality.

Description

technical field [0001] The invention belongs to the technical field of plasters, in particular to an evodia and ginger plaster and a preparation method thereof. Background technique [0002] Evodia rutaecarpa, the name of traditional Chinese medicine. It is the dry near-ripe fruit of Rutaceae plants Evodia rutaecarpa, Shihu or Evodia spp. From August to November, when the fruit has not yet cracked, cut off the fruit branches, dry in the sun or at low temperature, and remove impurities such as branches, leaves, and fruit stems. Evodia rutaecarpa is pungent in nature and flavor, bitter, hot, slightly poisonous, and returns to the liver, spleen, and stomach meridians. It is mainly used to treat stomach cold and pain. It can warm the interior and dispel cold to relieve pain. It also has the functions of promoting qi and relieving depression. [0003] Ginger, the name of traditional Chinese medicine. It is the fresh rhizome of ginger, a perennial herb of the Zingiberaceae fam...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K36/754A61K9/70A61K47/32A61K47/12A61K47/02A61K47/18A61K47/10A61K47/14A61P1/08A61P1/00A61P19/02A61P29/00
CPCA61K36/9068A61K36/754A61K9/7023A61K47/32A61K47/12A61K47/02A61K47/183A61K47/10A61K47/14A61P1/08A61P1/00A61P19/02A61P29/00A61K2236/333A61K2236/51A61K2300/00Y02A50/30
Inventor 任燕黄明进罗春丽胡利胡津秀
Owner GUIZHOU UNIV
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