37results about How to "Best extraction process" patented technology

The method for extracting dioscin and diosgenin includes the following steps: pulverizing rhizome of Chinese yam plant by adding water, fermentation by using lipolytic enzyme, separating cellulose and lignin, recovering supernatant, suspension and starch, mixing recovered liquors and filtering residue, boiling and filtering, repeating for several times, filtering residue for stand-by, combining filtrates and concentrating, using ethyl alcohol to make reflux extraction, cooling and filtering, decompressing and concentrating filtrate, adsorbing, evaporating, ethyl alcohol extracting, adding ethyl ether, cooling to room temp. and separating out tetrasaccharide saponin, recovering ethyl alcohol and ethyl ether from supernatant, precipitating out saponin, drying, adding water in starch and filter residue, regulating pH, adding alpha-amylase.

The invention relates to application of a salvianolic acid A composition in preparing medicines for protecting ischemic brain tissue damage. The composition is prepared from 94-97% of salvianolic acid A, 0.1-1.5% of alkannic acid, 0.1-1.5% of rosmarinic acid, 0.1-1.5% of salvianolic acid B and 0.1-2.0% of salvianolic acid C.

The invention relates to a method for ultrasonically extracting total flavones from tussilago farfara. The method comprises the following steps: (1) processing tussilago farfara, namely drying tussilago farfara in a constant-temperature drying box with temperature of 90 DEG C for 12 hours, grinding and sieving a 20-mesh sieve; (2) extracting, namely mixing the tussilago farfara processed in the step (1) with an ethanol solution according to a solution-material ratio (mL/g) of (20:1) to (30:1), and ultrasonically extracting under the power being 350W-500W for 30-45 minutes to obtain a total flavones extracting solution, wherein the volume fraction of ethanol in the ethanol solution is 30%-70%. The ultrasonic power, the ultrasonic extraction time and the material-solution ratio are optimized through a response surface method to obtain an optimal extraction process for ultrasonically extracting the total flavones from the tussilago farfara; the actually measured extraction rate in the process is 6.57%; the extraction condition is accurate and reliable and the extraction rate is relatively high; the method has the advantages of convenience, simplicity, quickness, safety and the like, provides corresponding reference data for extraction, development and utilization of effective ingredients of the tussilago farfara, and has an actual useful value.

The invention relates to optimization of a methyl nutritional type bacillus spore-production fermentation medium. The fermentation medium consists of the following components: 0.5-0.6% of corn meal, 0.08-0.2% of corn starch, 0.9-1.2% of bran, 0.18-0.54% of glucose, 0.05-0.15% of soybean cake powder, 0.16-0.2% of soybean peptone, 0.005-0.006% of KH2PO4, 0.006-0.008% of (NH4)2SO4, 0.004-0.005% of MnSO4, 0.0005-0.002% of CaCO3, 0.005-0.006% of MgSO4.7H2O, and the balance of water. The culture medium provided by the invention not only can meet the requirement of a shake flask fermentation experiment but also can successfully amplify the result of shake flask fermentation to a fermentation tank. Compared with the culture medium before optimization, the spore conversion rate and the spore yield of the formula of the culture medium are improved by 1-10 times, and the formula of the culture medium adopts low-price agriculture byproducts, so that the production cost is greatly reduced, and a foundation is laid for large-scale industrial production of wettable powder.

The present invention is one kind of medicine composition for treating female climacteric syndrome, endocrine and cardiac and cerebral vascular diseases and its preparation process. The medicine composition is prepared with nine kinds of Chinese medicinal materials, including conic gymnadenia tuber, silverweed cinquefoil root, mango stone, wolfberry fruit, fragrant rhododendron leaf, etc. Through water extracting, alcohol extracting, decompression concentrating, vacuum drying and other steps, the medicine composition is prepared into different pharmaceutically acceptable preparations. The medicine composition has obvious curative effect on the said diseases.

The invention discloses a method of improving an antioxidant activity of walnut cake protein. The method of improving the antioxidant activity of the walnut cake protein includes the following steps of: 1, testing influences of enzyme types on a walnut cake protein yield; 2, testing influences of enzyme addition amounts on the walnut cake protein yield; 3, testing influences of material-liquid ratios on the walnut cake protein yield; 4, testing influences of grain sizes on the walnut cake protein yield; 5, testing influences of extraction time on the walnut cake protein yield; 6, measuring thecontent of the protein in an extraction solution; 7, conducting enzyme-assistant walnut cake protein extracting response surface experiments; and 8, analyzing the influences of the enzyme types on the walnut cake protein yield. By adopting the method of improving the antioxidant activity of the walnut cake protein, the problems are solved that current methods cannot be applied to the fields of food and drugs, during experiments of the current methods, temperature control is involved, the single-factor cost is high, a safety factor is low, the antioxidant activity of the prepared walnut cake protein is extremely low, and through a buffer solution, a high protein yield cannot be reached.

The invention relates to an immune potentiator based on hirsutella sinensis and a preparation method thereof. The potentiator is white dried powder and mainly composed of saccharides, amino acids andderivatives thereof and nucleosides compounds, and the potentiator is provided with an immune enhancing effect, can improve the immunity of the body and has a broad market. The culturing of the hirsutella sinensis is optimized by methods of adding metabolism induction materials and the like to allow the immunity active substances in a cultured substance to be increased; the optimal extracting technology of the immunity active substances in the obtained hirsutella sinensis is obtained through extracting and the optimization of a spectrum separation preparation technology. The immunity active substances are mainly obtained from a hirsutella sinensis solution, and bi-produc thirsutella sinensis filaments can replace related health protection products of wild cordyceps sinensis processing, anddual-purpose is achieve. According to the method, the immune potentiator is produced through indoor fermentation, the industrial production of the immune potentiator can be conducted all year round,the production is not influenced by severe environmental factors of plateau low temperature of the wild cordyceps and the like, and the ecological environment is not damaged.

The invention discloses a method for extracting taurine from an octopus liver. The method for extracting the taurine from the octopus liver comprises the steps that methods of pretreatment, self-digestion, extraction, deacidification, de-basic protein, decoloration concentration, ion exchange adsorption, eluant collection and ethyl alcohol and recrystallization addition are carried out on the octopus liver to obtain a taurine pure product. According to the method for extracting the taurine from the octopus liver, the taurine extraction rate is used as an index, the taurine is extracted from the octopus liver by adopting a water-boiling method, the influence of four factors of feed liquid ratio, extraction temperature, extraction time and self-digestion time on the taurine extraction rate is studied, and an optimum extraction process is optimized through orthogonal experiment. The preparation process has no pollution, the process is simple and easy to operate, the cost is lower, resin is reproducible, the obtained product purity is high, and good practical significance and application prospects are achieved.

The invention provides a preparation method for sargassum confusum C.Ag. phlorotannins. The preparation method comprises the steps: evenly mixing dried sargassum confusum C.Ag. and a 40 vol% ethanol solution with the amount 20 times that of the dried sargassum confusum C.Ag., carrying out water bath extraction for 46 min at the temperature of 30 DEG C, centrifuging the extract liquid for 10 min at the speed of 4000 r/min, repeating extraction for 2 times, and thus obtaining a phlorotannins extract liquid. The method for optimizing the sargassum confusum C.Ag. phlorotannins best extraction conditions by a response surface method is used, and 3 independent variables comprising the ethanol volume fraction, the material-to-liquid ratio and the extraction time are set; screening is performed by using a Box-Benhnken response surface design principle; experimental design and result analysis are performed by using Design expert software; the exaction technology of the sargassum confusum C.Ag. phlorotannins improves the extraction rate of the phlorotannins, and plays an important role in industrialized production of the phlorotannins.

The invention discloses a kidney tonifying and life lengthening tablet preparation technology. A formula of the kidney tonifying and life lengthening tablet is prepared from the following raw materials in parts by weight: 120 to 130 parts of radix ginseng rubra, 4.0 to 5.0 parts of pearl powder, 310 to 320 parts of lucid ganoderma, 625 to 635 parts of prepared radix polygoni multiflori, 625 to 635 parts of fructus lycii, 940 to 950 parts of herba epimedii, 310 to 320 parts of radix salvia miltiorrhizae, 120 to 130 parts of liquorice root and 310 to 320 parts of rhizoma polygonati. The kidney tonifying and life lengthening tablet can be prepared through the steps of alcohol extracting the radix ginseng rubra and the herba epimedii, one step granulating through a fluidized bed, extracting materials, concentrating, mixing and drying. According to the kidney tonifying and life lengthening tablet preparation technology, effective ingredients of the radix ginseng rubra and the herba epimedii in the formula are fully utilized. The kidney tonifying and life lengthening tablet is small in loss of effective ingredients and stable in quality.

The invention relates to a salvianolic acid A capsule comprising by weight 5%-60% of a salvianolic acid A composition, 94.9%-39.5% of a filler and 0.1%-0.5% of a lubricant. The salvianolic acid A composition comprises salvianolic acid A more than 93% and less than 100%, and other 4 ingredients including 0.1%-2% of alkannic acid, 0.1%-2% of rosmarinic acid, 0.1%-2% of salvianolic acid B, 0.1%-2% of salvianolic acid C. The filler is one or more selected from starch, dextrin, sucrose, mannitol, microcrystalline cellulose, pregelatinized starch and calcium sulfate. The lubricant is one or more selected from magnesium stearate, talcum powder, superfine silica powder and polyethylene glycol. The invention also discloses application of the salvianolic acid A capsule to preparation of medicine for preventing and / or treating ischemic cerebrovascular disease.

The invention discloses a traditional Chinese medicine compound composition capable of treating infantile constipation and a preparation method thereof. The traditional Chinese medicine compound composition is prepared from 6-15 parts of immature bitter orange, 6-15 parts of magnolia officinalis, 6-15 parts of snakegourd root, 6-15 parts of fructus forsythiae, 6-15 parts of medicated leaven, 6-15parts of fried cassia seed, 3-5 parts of rhubarb, and 3-9 parts of chicken's gizzard-membrane. The traditional Chinese medicine compound composition provided by the invention provides treatment according to differentiation of symptoms and signs on the basis of the theory of traditional Chinese medicine and has a scientific prescription according to the pathogenesis of infantile constipation; and experimental research results prove that the traditional Chinese medicine compound composition provided by the invention has scientific and reasonable proportion of each component, can obviously improve the activity of pepsin in rats, has a promoting effect on a propulsion function of small intestines in mice, and can reduce serum SS of the mice, and increase MTL and GAS, thereby regulating gastrointestinal hormones and promoting gastrointestinal peristalsis. Moreover, clinical experimental results show that the traditional Chinese medicine compound composition has a very good therapeutic effect on infantile constipation, and has good safety and no toxic or side effects.

The invention relates to a method for preparing taurine by high-voltage pulsed electric field assisted enzymolysis of freshwater mussel meat, and aims to solve the problem of lack of a method for extracting taurine from freshwater mussel meat at present. The high-purity natural taurine product is effectively extracted from freshwater mussel meat through the steps of raw material pretreatment, wallbreaking treatment, high-voltage pulsed electric field treatment, enzymolysis, filtration, purification, crystallization and the like, the production process is environmentally friendly and efficient, the test operation is simple, the taurine extraction effect is improved, the problems of freshwater mussel byproduct resource waste, environment pollution and the like are solved, the taurine extraction amount is used as an index, the four factors of the electric field intensity, the pulse number, the enzyme addition amount and the enzymolysis time are optimized, and the taurine extraction amount of freshwater mussel meat is greatly increased.

The invention discloses an optimal extraction process of polyphenol in tinder fungus. The optimal extraction process comprises the following steps: single-factor experiment, response surface design, determination of optimal extraction conditions of polyphenol in the tinder fungus, and determination of crude extract polyphenol content,. wherein the single-factor experiment comprises drawing of a standard curve, influence of ethanol concentration on extraction of tinder fungus polyphenol, influence of material-liquid ratio on extraction of the polyphenol in the tinder fungus, influence of ultrasonic time on extraction of the polyphenol in the tinder fungus, influence of ultrasonic temperature on extraction of the polyphenol in the tinder fungus, influence of extraction times on extraction ofthe polyphenol in the tinder fungus, and multiple experimental principle steps. According to the optimal extraction process of the polyphenol in the tinder fungus, the influence of the ethanol concentration, the material-liquid ratio, the ultrasonic time, the ultrasonic temperature and the extraction frequency on extraction of the polyphenol in the tinder fungus is determined by designing a single-factor experiment, and the optimal extraction process is obtained by designing a response surface. Reference is provided for development and utilization of the polyphenol in the tinder fungus.

The invention relates to an extraction condition optimization method and an extraction method of tripterygium multi-index active ingredients. The extraction condition optimization method is characterized in that against optimal extraction of the tripterygium multi-index active ingredients, an ultrasonic extraction process of the tripterygium active ingredients in the prior art is integrated, through single-factor experimental investigation, three factors, namely liquid-to-solid ratio, solvent concentration and ultrasonic power, which have relatively great effects on extraction overall desirability value (OD value) of the tripterygium multi-index active ingredients, are selected, design expert software is utilized, and a star point design-response surface optimization method is applied for optimization, so that optimal extraction process parameters are obtained. The methods provided by the invention are simple, the experimental precision is high, the optimal values are calculated by model fitting, resources and energy consumption are saved, and a guide can be provided for industrialized extraction and production.