249 results about "Urinary tract function" patented technology

The invention relates to the technical field of medical instruments, and discloses a urinary system calculus discharge promoting device and a calculus extractor, the urinary system calculus discharge promoting device comprises a guide wire, the front end of the guide wire is provided with a mesh basket used for catching broken stones and an expansion body which expands after absorbing water and is used for blocking the broken stones in a ureter, and the expansion body is arranged in the length direction of the guide wire. The expansion body is positioned at the front end of the net basket; the mesh basket is composed of a plurality of first mesh basket wires; through cooperation of the traction assembly, the fixing assembly and the expansion body which absorbs water and expands, the rear ends of the first mesh basket wires are pulled to deform, broken stones in the mesh basket are tightened and then taken out, and the situation that when large broken stone water chestnuts are taken out, the inner wall of the ureter is scratched, and consequently human organs are injured is avoided; small calculi are prevented from further moving towards the upper end of the ureter or even the kidney, and the situation that due to the fact that the calculi are accumulated at the joint of the pelvis and the ureter, normal discharge of urine is possibly blocked, urine in the pelvis is accumulated, and hydronephrosis is formed is avoided.

The present invention provides a method for evaluating urinary system diseases based on urine detection, which belongs to the technical field of urology. The method for evaluating urinary system diseases based on urine detection comprises: adding corresponding reagents to three urine samples in sequence according to a preset time point sequence, and obtaining urine sample images after each addition of the reagents; performing image preprocessing on each acquired urine sample image, extracting image features including color changes, sediment morphology and distribution; establishing a time series feature data set, arranging and combining the image features corresponding to each time point in time sequence; using a pre-trained image recognition model to analyze the image features in the time series feature data set, and obtaining feature vectors; the method can solve the problems of high examination cost, great trauma, long examination time, limited diagnostic accuracy, etc. that the existing means of diagnosing urinary system diseases generally have.

The invention relates to the technical field of medical image processing and intelligent diagnosis. The image recognition method for the urinary system calculus comprises the steps that a dynamic video stream of a calculus area is obtained through an endoscope image collection module, and a current frame image is extracted; performing illumination compensation processing on the image, eliminating vascular interference and light reflection, and enhancing the boundary of a calculus main body; based on multispectral feature fusion, separating yellow-like spectrum features of uric acid stones and grey-white-like spectrum features of calcium stones, and calculating stone surface color distribution dispersion; performing multi-angle texture energy detection by adopting a direction sensitive convolution kernel to generate a calcification crystallization density coefficient; inputting the color distribution dispersion and the calcification crystallization density coefficient into a decision tree model, and outputting a calculus type identifier; and according to the stone type identifier and the three-dimensional projection area of the stone contour, frequency-energy combination parameters of the laser stone crusher are generated, and the laser pulse emission time sequence is controlled in real time.

The invention discloses a urinary system infection pathogen and drug resistance gene detection system and a kit. The detection system comprises forward and reverse primers which are respectively used for detecting escherichia coli, staphylococcus aureus, acinetobacter baumannii, klebsiella pneumoniae, enterococcus faecium, candida glabrata, proteus mirabilis, enterococcus faecalis, candida tropicalis, enterobacter cloacae, candida albicans, pseudomonas aeruginosa and streptococcus agalactiae; the forward primer and the reverse primer are respectively used for detecting the blaCTX-M gene of the extended spectrum beta-lactamase, the forward primer and the reverse primer are used for detecting the blaSHV gene of the extended spectrum beta-lactamase, and the forward primer and the reverse primer are used for detecting the blaTEM gene of the extended spectrum beta-lactamase. According to the forward and reverse primers for detecting the blaNDM gene of the extended-spectrum beta-lactamase, a detection sample is urine. According to the invention, common gram-negative bacteria, gram-positive bacteria and fungi can be detected at the same time, and the problem of missed detection of mixed infection in traditional culture is solved.

The present disclosure relates to detecting one or more types of urinary system cancer in a biological sample from a subject. In particular, the present disclosure provides compositions and methods for detecting the presence or absence of one or more types of urinary system cancer (e.g., urothelial carcinoma and / or renal cell carcinoma) in a biological sample from a subject suffering from or suspected of suffering from urinary system cancer.

The invention relates to the technical field of image recognition, in particular to a urinary system CT image tumor benign and malignant identification method based on deep learning, which comprises the following steps: acquiring a urinary system CT image, constructing a map band sequence and extracting gray level distribution, identifying a heterogeneous edge and a texture mutation region, aggregating perturbation map blocks to form an abnormal structure, and identifying the benign and malignant tumors. And fusing multiple types of image layers to complete label integration, and generating a feature recognition image layer. According to the method, the extension recognition capability of the tumor edge external expansion region is enhanced by combining a graph band gray scale aggregation and sequence construction mode, the judgment precision of local heterogeneous change is improved by fusing gray scale kurtosis and migration analysis, and the texture disturbance trend is extracted based on direction vector included angle change. The block gray level fluctuation and gradient relationship supports abnormal structure aggregation identification, spatial coincidence and boundary difference combined screening realizes multi-feature region unified coverage, abnormal region expression definition and structure positioning accuracy are enhanced, and image layer consistency and identification stability are improved.

The invention discloses an intelligent image analysis system and method for urinary system calculus detection, relates to the technical field of intelligent image systems for urinary system calculus detection, and is used for solving the dynamic adjustment of an ultrasonic image gray scale fixed value. More accurate, flexible and intelligent calculus detection is realized by combining the gray processing of the urinary system ultrasonic image, the boundary judgment of the root mean square contrast and the influence of the urine pH value on the calculus type. Through fusion of multi-modal information, dynamic adjustment of a threshold value, calculus type identification capability and automatic processing capability, the detection precision can be improved, and the method can be applied to clinical application of urinary system calculus detection.

The invention relates to the field of animal consumer goods, and particularly discloses application of glucan in preparation of animal products for relieving pet stress syndromes. Pet experiments find that beta-1, 3 / alpha-1, 3-glucan can improve the stress syndromes of the indoor cats, specifically, abnormal behaviors of the cats are corrected, and abnormity of multiple systems of organisms such as the immune system, the endocrine system and the urinary system is improved. And when the method is applied to pets, the life quality of the pets can be remarkably improved, more emotional support is provided for pet owners, and the method has practical popularization and application values.

The invention provides a urinary system calculus discharge promoting device and a calculus extractor, and relates to the technical field of urinary surgery equipment. Comprising a first taking-out branch pipe, a second taking-out branch pipe is arranged in the first taking-out branch pipe in a sleeved mode, a filling air bag is arranged at the end of the first taking-out branch pipe, a stone crushing mechanism is arranged at the end of the second taking-out branch pipe, a third taking-out branch pipe is arranged in the second taking-out branch pipe in a sleeved mode, and a stone crushing ejector pin is arranged on the inner side of the third taking-out branch pipe; the outer end of the third taking-out branch pipe is connected with a pressure pumping device; compared with the prior art, the lithotripter is simple in structure, convenient to use, capable of effectively completing lithotripsy operation and convenient for lithotripsy.

The invention relates to the technical field of medical data analysis, in particular to a urinary system tumor big data analysis system which comprises a target kernel generation module, a kernel matrix calculation module, a parameter optimization module and a risk division module. According to the method, a target kernel matrix reflecting clinical prognosis differences is constructed and serves as an optimization reference, a radiomics and genomics feature kernel matrix is generated through hardware acceleration parallel computing, kernel function width parameters are dynamically iteratively updated based on an alignment degree numerical value so as to ensure that multi-modal feature distribution is highly matched with a prognosis label, and the accuracy of the multi-modal feature distribution is improved. A multi-dimensional feature space containing rich pathological information is constructed by combining a weighted fusion mechanism after centralization processing, so that a support vector machine is trained to determine a high-robustness decision boundary, and precise division of tumor risk levels is realized while high-dimensional data calculation delay is greatly reduced; and the reliability and timeliness of auxiliary diagnosis and treatment results in a complex pathological environment are effectively improved.

The invention relates to the technical field of nutritional supplements, and discloses a pet nutritional supplement capable of improving immunity, which is prepared from the following raw materials in parts by weight: 35 to 45 parts of taurine, 5 to 8 parts of natural lutein, 10 to 30 parts of chondroitin sulfate, 10 to 20 parts of water, 20 to 30 parts of corn starch, 10 to 20 parts of semen plantaginis and 30 to 50 parts of microbial fermentation products. The 35-45 parts of taurine and the 10-30 parts of chondroitin sulfate can be selected from one or more of sardine powder, black and white fish powder, beef powder, pig powder, chicken powder and the like. According to the pet nutritional supplement capable of improving immunity and the preparation method thereof, the semen plantaginis is added into the raw materials, so that the pet kidney can be promoted to generate more urine, urethra flushing is facilitated, bacterium breeding is reduced, and urinary system infection is prevented, and the taurine is added, so that heart condition improvement, brain development promotion and retina protection are facilitated. When the pet supplement is prepared, the pet supplement is prepared by using a freeze-drying machine, so that the loss of nutrient substances is reduced.

The present invention relates to a visualized bladder puncture fistula drainage device, which belongs to the field of urinary system surgical instruments and comprises: a puncture sheath used for being inserted into the surface of the bladder through an incision to isolate an operation channel; a visualized puncture assembly connected to the puncture sheath; a puncture needle core connected to one end of the visualized puncture assembly, an optical fiber integrated body wrapped on the outside of the puncture needle core, and the end of the optical fiber integrated body facing the needle tip of the puncture needle core is tapered; an image acquisition end connected to the inner side of the visualized puncture assembly, and the image acquisition end is optically coupled with an end of the optical fiber integrated body away from the needle tip of the puncture needle core; a display screen connected to the end of the visualized puncture assembly away from the puncture needle core, the display screen is communicatively connected to the image acquisition end, and the image acquisition end acquires an image of the needle tip end of the puncture needle core through the optical fiber integrated body and transmits it to the display screen; the device can solve the technical problem that the visualized puncture in the prior art cannot effectively avoid the vascular area on the surface of the bladder without causing additional wounds, thereby causing infection.

The invention provides a transmembrane state evaluation system and method for a bladder three-dimensional form, and is applied to the technical field of data processing. The method comprises the following steps: preprocessing bladder ultrasonic image information of a target patient to generate target ultrasonic image sequence information; processing the target ultrasonic image sequence information to generate a target enhanced ultrasonic image; processing the physiological parameter information of the urinary system of the patient based on the target bladder morphology evaluation model to generate a target physiological status feature; processing the target physiological status features, the target enhanced ultrasound image and the functional image data based on the target bladder morphology evaluation model to generate a predicted CT image of the target patient; and processing the predicted CT image of the target patient and the simulated positioning CT image information of the target patient based on the target bladder form evaluation model in combination with the bladder dynamic image information to generate a bladder three-dimensional form evaluation result.

The present invention belongs to the technical field of urinary system drug preparations, and specifically relates to a tamsulosin hydrochloride preparation and a preparation method thereof. The prior art has the defects that tamsulosin hydrochloride is not effective in treating prostatic hyperplasia and has large side effects. The present invention combines tamsulosin hydrochloride with cinnamon extract, and uses animal experiments to prove that tamsulosin hydrochloride and cinnamon extract can not only play a synergistic effect, but also reduce the side effects of tamsulosin hydrochloride such as hypotension and fatigue.

The invention provides a brain injury simulation human teaching model which comprises a simulation human body with a head, a body and four limbs. A craniocerebral simulation unit for simulating encephaledema, encephaloma, brain fracture, cerebral hernia and cerebrospinal fluid leakage is arranged in the head part; a urinary system simulation unit, a blood circulation system simulation unit and a respiratory system simulation unit are arranged in the body; control programs of response of the urinary system simulation unit, the blood circulation system simulation unit and the respiratory system simulation unit corresponding to different brain injuries are preset in the controller; an operator selects different brain injuries and nurses the brain injuries and complications of the urinary system simulation unit, the blood circulation system simulation unit and the respiratory system simulation unit. The brain injury can be nursed through the craniocerebral simulation unit, the complication of the brain injury can be nursed through the urinary system simulation unit, the blood circulation system simulation unit and the respiratory system simulation unit, and the brain injury nursing system is more consistent with the actual situation and is beneficial to teaching.

The invention belongs to the technical field of medical image modeling, and particularly relates to a urinary system blood vessel modeling method based on 3D Gaussian splashing and a surgical robot navigation method.The blood vessel modeling method comprises the steps that a data source is preprocessed, and a urinary system blood vessel model is constructed; describing the center line and the section shape of the blood vessel based on a Bezier curve and an NURBS curve, and realizing dynamic 3DGS modeling of the blood vessel; dynamic 3DGS modeling, finite element analysis and computational fluid mechanics are combined, and hemodynamics simulation is achieved through a two-way mapping algorithm of Gaussian parameters and finite element grids. Compared with the prior art, the method solves the problem that in the prior art, due to the fact that a high-precision model for the dynamic characteristics of the blood vessels of the urinary system is lacked, accurate navigation and operation of urinary system interventional operation are difficult. According to the scheme, a high-precision model is constructed for urinary system blood vessels (such as renal arteries and bladder blood vessels) based on the three-dimensional Gaussian sputtering technology, and precise navigation and operation of urinary system interventional operations are effectively assisted.

The invention aims to provide a preparation method of amnion-derived mesenchymal stem cells with high collagen expression. The preparation method comprises the following steps: step 1, reagents and materials: amnion tissues: obtaining a fresh amnion from a healthy puerpera after delivery; the PBS is used for cleaning amniotic tissues; collagenase: type I collagenase, which is used for digesting amniotic tissues to separate mesenchymal stem cells; a cell culture medium is a DMEM / F12 culture medium, and 10% of fetal calf serum and 1% of penicillin-streptomycin double antibodies are added; the transforming growth factor TGF-beta is used for promoting the expression of mesenchymal stem cell collagen; and the fibroblast growth factor FGF can assist in promoting cell proliferation and collagen expression. The invention aims to provide the preparation method of the amniotic membrane-derived mesenchymal stem cells for highly expressing collagen, and the amniotic membrane-derived mesenchymal stem cells can be widely applied to treatment of immune system diseases, reproductive system diseases, skin system diseases, skeletal system diseases, nervous system diseases, digestive system diseases, respiratory system diseases, circulatory system diseases and urinary system diseases. Particularly, the effects of immunosuppression and tissue repair are achieved.

The application provides a craniocerebral injury simulation man teaching model, which comprises a simulation man body provided with a head, a body and limbs; the head is internally provided with a craniocerebral simulation unit for simulating brain edema, brain hematoma, brain fracture, brain hernia and cerebrospinal fluid leakage; the body is internally provided with a urinary system simulation unit, a blood circulation system simulation unit and a respiratory system simulation unit; the controller is prearranged with control programs of reactions of the urinary system simulation unit, the blood circulation system simulation unit and the respiratory system simulation unit corresponding to different brain injuries; an operator selects different brain injuries and carries out nursing on the brain injuries and the complications of the urinary system simulation unit, the blood circulation system simulation unit and the respiratory system simulation unit. The application can not only nurse the brain injuries through the craniocerebral simulation unit, but also nurse the complications of the brain injuries through the urinary system simulation unit, the blood circulation system simulation unit and the respiratory system simulation unit, so that the application is more consistent with the actual situation and is beneficial to teaching.

The present invention relates to the field of traditional Chinese medicine. Specifically, it relates to a traditional Chinese medicine composition for treating urinary system diseases and its application. It is characterized in that it is made from traditional Chinese medicines in the following parts by weight: 30-70 parts of Lysimachia christinae Hance, 20-50 parts of Astragalus membranaceus (Fisch.) Bunge, 20-50 parts of Lygodium japonicum (Thunb.) Sw., 20-50 parts of Endothelium corneum gigeriae galli, 10-30 parts of Cuscuta chinensis Lam., 10-30 parts of Pyrrosia lingua (Thunb.) Farwell, and 3-10 parts of Glycyrrhiza uralensis Fisch. The traditional Chinese medicine composition of the present invention contains Lysimachia christinae Hance, Astragalus membranaceus (Fisch.) Bunge, Lygodium japonicum (Thunb.) Sw., Endothelium corneum gigeriae galli, Cuscuta chinensis Lam., Pyrrosia lingua (Thunb.) Farwell, and Glycyrrhiza uralensis Fisch. Compared with the existing traditional Chinese medicine compositions, its components are simplified; and the present application optimizes the addition ratio of alcohol extraction and the percentage of alcohol solution. With the optimized parameters, it can obtain polyphenols and flavonoids to the maximum extent and has a high DPPH free radical scavenging rate. Subsequently, animal experiments and clinical experiments prove that it can effectively treat urinary system diseases and has great clinical value and economic value.

This invention provides a transmembrane assessment system and method for three-dimensional bladder morphology, applied in the field of data processing technology. This application preprocesses bladder ultrasound image information of a target patient to generate target ultrasound image sequence information; processes the target ultrasound image sequence information to generate target enhanced ultrasound images; processes the patient's urinary system physiological parameters based on a target bladder morphology assessment model to generate target physiological state characteristics; processes the target physiological state characteristics, target enhanced ultrasound images, and functional imaging data based on the target bladder morphology assessment model to generate a predicted CT image of the target patient; and processes the predicted CT image and simulated localization CT image information of the target patient based on the target bladder morphology assessment model combined with bladder dynamic image information to generate a three-dimensional bladder morphology assessment result.

The utility model discloses a sterile portable combined bag which comprises an outer package and a combined bag body arranged in the outer package, the combined bag body comprises a first tray and medical wrapping cloth wrapping the surface of the first tray, and a water injector placing groove is formed in one side, located on the long edge, of the first tray. A first groove is formed in the side face of the water injector containing groove, a second groove and a third groove are formed in the positions, on the two sides of the first groove, of the short edge of the first tray respectively, and a second tray and a third tray are arranged in the first groove. The disposable urinary catheter is convenient to use, avoids urinary system disease infection and venereal disease infection, is convenient to test, is not easy to age, is inconvenient for family patients to use, is reasonable in article configuration, is safe and reliable, is low in cost, and is convenient to carry.

A method for training a prediction model for a lower urinary tract symptom risk score is disclosed. A method for training a prediction model for a lower urinary tract symptom risk score according to an embodiment comprises the steps of: obtaining numerical data of a urinary system; obtaining graph data of the urinary system; obtaining composite graph data in which the numerical data is reflected in the graph data; obtaining a numerical feature map corresponding to the numerical data; obtaining a composite graph feature map corresponding to the composite graph data; and training the prediction model for the lower urinary tract symptom risk score on the basis of the numerical feature map and the composite graph feature map.

1. The name of the product of this design: Pulse energy control graphical user interface for electrohydraulic lithotripsy. 2. Purpose of the product with this design: The electrohydraulic lithotripter is used to treat urinary stones and stones in gallbladder and pancreatic diseases, and uses shock waves generated by high-voltage electric pulses to break up stones in the body; the pulse energy control graphical user interface is used to adjust the size of the pulse energy, select the pulse mode, and display the value and change status of the pulse energy. 3. The key design point of this design product lies in the content of the product's graphical user interface. 4. The picture or photo that best illustrates the design points: Interface change state diagram 2. 5.Purpose of the graphical user interface: The pulse energy control graphical user interface is used to adjust the pulse energy, select the pulse mode, and display the value and change status of the pulse energy. 6. The area of ​​the graphical user interface in the product: the display screen of the main view. 7. Human-computer interaction of the graphical user interface: After booting up and entering the pulse energy control main interface (the user interface in the main view), click Single Pulse in the Pulse Mode column on the right. The option changes color, indicating that the Single Pulse option is selected. The "lightning" icon in the energy ring in the middle of the interface changes to a "Single Pulse" icon (as shown in the interface change state Figure 2). Click the plus circle or minus circle below the energy to adjust the energy value. The energy value is adjusted within the range of 0-400MJ. The pointer of the corresponding energy ring will point to the adjusted energy value (as shown in the interface change state Figure 2-8); click the Start / End option in the lower left corner of the main interface (as shown in the interface change state Figure 9) to start or end energy transmission.

The present application relates to medical image recognition technology field, specifically to a kind of based on frame segment stabilization and gray enhancement feature urinary system tumor screening method, comprising the following steps: extracting stable frame section, generating kidney reference template, establishing cortex gray contrast, combined template analysis enhancement feature, locate screening area and delineate boundary, generate tumor screening set.In the present application, by identifying image sequence gray level jump, avoid the interference of abnormal frame to image processing, combined with edge gradient change extraction structure boundary clarity minimum frame as anatomical structure reference image, using spatial position mapping to carry out dynamic analysis of cortex area gray change, make the direction, amplitude and duration of enhancement response more accurate, and then complete the automatic screening and boundary delineation of suspicious area, ensure that screening positioning result is continuous in time and consistent in space, improve lesion identification accuracy and objectivity of result, generate image set of urinary system tumor suspected area.

The present invention relates to the field of medical image processing and intelligent diagnosis technology. It provides an image recognition method for urinary system stones, including obtaining a dynamic video stream of the stone area through an endoscopic image acquisition module and extracting the current frame image; performing light compensation processing on the image to eliminate blood vessel interference and reflection and enhance the boundary of the main body of the stone; based on multi-spectral feature fusion, separating the yellowish spectral features of uric acid stones and the grayish-white spectral features of calcium stones, and calculating the color distribution dispersion degree of the stone surface; using a direction-sensitive convolution kernel to perform multi-angle texture energy detection to generate a calcification crystal density coefficient; inputting the color distribution dispersion degree and the calcification crystal density coefficient into a decision tree model to output a stone type identifier; generating frequency-energy combination parameters of a laser lithotripter according to the stone type identifier and the three-dimensional projected area of the stone contour, and real-time controlling the laser pulse emission timing sequence.

The invention discloses a urinary system pressure measurement signal processing method and system based on biological feature recognition, and the method comprises the steps: injecting a standard pressure source to simulate a known load, collecting a calibrated pressure signal of a pressure sensor, analyzing the spectral characteristics, and constructing a baseline noise model; extracting biological features to establish an interference feature library; acquiring a real-time pressure signal of a patient, and stripping an environmental noise component through filtering based on a baseline noise model; and matching the real-time pressure signal after the noise component is stripped with an interference feature library, and starting targeted filtering enhancement on matched interference features to obtain a filtered pressure signal. According to the method, the problem of signal distortion caused by noise interference and human factors in urinary system pressure measurement can be solved, and the reliability of a measurement result and the accuracy of diagnosis are improved.

The invention belongs to the technical field of medical artificial intelligence, and particularly discloses a prediction method of urinary system cancer categories and an evaluation method of biomarkers of the urinary system cancer categories. According to the method, a feature extraction algorithm and a Raman attention neural network are developed aiming at the SERS spectrum of urine, a healthy control group, a benign urinary disease group, a bladder cancer group, a kidney cancer group and a prostate cancer group are successfully distinguished, and the overall accuracy rate is 94.87%. In particular, the invention provides a method for evaluating biomarkers of cancer classes of the urinary system, successfully reveals that cancer diagnosis depends on differences of specific biomarker levels, and determines effective biomarkers of cancers. Research finds that most biomarkers are positively correlated with positive prediction, and the cancer specific biomarkers are particularly important, which provides important guidance for the clinical basis fuzzy problem of the current novel disease diagnosis technology.

The application provides a method and device for identifying a lesion range of a urinary system by using interference optics, and the method comprises the following steps: obtaining a polarized image corresponding to a multi-layer optical rotation tomogram by filtering through a polaroid, and generating an original polarization image containing interference fringes and tissue texture; performing line extraction, intersection removal, Gaussian mask and smoothing reconstruction processing on the original polarization image to generate an interference bright line image; according to the light and dark distribution of the interference bright line image, optical rotation calculation and Mueller matrix correction are sequentially performed to generate tissue optical rotation distribution data; and the lesion range is identified by matching the tissue optical rotation distribution data with a preset calibration sample. Through multi-wavelength orthogonal polarization interference and optical rotation accurate detection, the ability to distinguish flat lesions and inflammatory mucosa is improved from the root, and the lesion boundary identification accuracy and identification efficiency are significantly improved.

The present invention provides a medicinally active extract obtained from the plant Polyspora axillaris ( Polygala japonica Houtt. ), which contains flavonol compounds of the following formula (I) as the first active ingredient, and optionally contains xanthone compounds of the following formula (II) as the second active ingredient and glycolipid compounds of the following formula (III-1) or (III-2) as the third active ingredient. Animal experiments have confirmed that the drug of the present invention is significantly superior to potassium sodium hydrogen citrate in typical test indexes such as calcium oxalate crystal aggregation, renal interstitial inflammatory cell infiltration and renal tubular dilation lesions, indicating that it has extremely good potential and market prospects in the treatment of urinary system lithiasis and urinary tract infections or kidney injuries caused by urinary system lithiasis, and as an adjuvant drug after surgical treatment of urinary system lithiasis. (I) (II) (III).

A multi-efficacy traditional Chinese medicine compound composition and application thereof in pharmaceutical preparations are disclosed. The traditional Chinese medicine extracts are combined with the glucosamine, the collagen and the chondroitin sulfate, so that the multi-efficacy traditional Chinese medicine compound composition is prepared. The traditional Chinese medicine compound composition starts from improving the health of bone and joint and accompanying cardiovascular disease, selects the medicinal materials, and optimizes the extraction process of the traditional Chinese medicine for the diseases dominated by degenerative osteoarthritis. The disclosure has the efficacious of improving the symptoms of degenerative osteoarthritis, reducing blood pressure, improving the symptoms with osteoporosis, improving the symptoms with cardiovascular disease, improving the symptoms with urinary system disease, etc. It also has the characteristics of less dosage, significant curative effect and various functions, which is suitable for market promotion and application.