Arachis hypogaea L. nerve-soothing oral liquid and preparing method and application thereof
A technology of oral liquid and groundnut branches and leaves, which is applied in the fields of pharmaceutical formulations, dispersion liquid delivery, nervous system diseases, etc., can solve problems such as research on effective chemical components that do not have the sedative and hypnotic effects of groundnut branches and leaves, and achieve the effect of increasing the content
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Embodiment 1
[0018] Embodiment 1 Pharmacological screening of index components of groundnut branches and leaves
[0019] There is no relevant literature report on the research on the chemical constituents of groundnut branches and leaves for treating insomnia. In order to establish the index compounds of Arachis twigs and leaves, we worked closely with the Pharmacology Department of Shanghai Staff Medical College to screen the active substances.
[0020] Take 2 kg of chopped groundnut branches and leaves, add 20 times the amount of water and boil for 1 hour, filter the decoction, add 10 times the amount of water and boil for 1 hour, filter the decoction, combine the second decoction, and concentrate under reduced pressure in a 70°C water bath to 2000ml, add n-butanol 0.8L x 2 times, extract 0.4L x 1 time, wash the n-butanol extract with 250ml deionized water x 2 times, then concentrate at 70°C under reduced pressure to dryness, dry at 70°C in vacuum, weigh 32 grams.
[0021] The aqueous ...
Embodiment 2
[0064] Embodiment 2 The research of Luohua Anshen oral liquid preparation technology
[0065] 1. Research on raw material extraction process
[0066] 1.1 Identification and pretreatment of medicinal materials
[0067] 〔Peanut branches and leaves〕
[0068] This product is the dry aerial part of Arachis hypogaea L., a leguminous plant. There are not many studies on the chemical constituents of Arachis branches and leaves [5,10]. Water, alcohol, petroleum ether and other extracts of groundnut branches and leaves have sedative and hypnotic effects [7]. "National Compilation of Chinese Herbal Medicine" records that 60g of groundnut fresh leaves are fried into 15-20ml and taken orally before going to bed, which has sedative and hypnotic effects. A recent study by the research group found that the amino acid content of the branches and leaves of groundnut with strong pharmacological sedative and hypnotic effects is higher, and the total nitrogen content is still about 2% after al...
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