26results about How to "Shorten experiment time" patented technology

The application discloses a kind of high-pressure fuel filter prediction model construction method and flow prediction method, including two prediction models, method specifically includes: using computational fluid dynamics method carries out fluid dynamics simulation calculation to high-pressure fuel filter, constructs working condition sample data set;The size of filter hole, quantity, filter working pressure, fuel viscosity and filter pressure drop are used as input variable, and filter flow is used as output variable, two new high-pressure filter general nonlinear flow prediction models are established using artificial neural network and regression prediction method respectively, the flow characteristics of different models of filter in working interval can be accurately predicted using the neural network prediction method proposed in the application at any working condition point, and the error is low;The flow of different models of filter under different conditions can be quickly and accurately obtained, the accuracy meets the engineering needs, while greatly shortening the experimental time and calculation time, saving design cost.

The application belongs to the technical field of medicine, and particularly relates to a method for embedding micro-organoids or cells with agarose. The method for embedding micro-organoids or cells with agarose comprises the following steps: 1) fixing micro-organoids or cells with a fixing solution; 2) washing the fixed organoids or cells, removing supernatant after centrifugation, and obtaining organoid or cell precipitate; 3) pre-embedding organoids or cells with agarose; 4) taking out the agarose pre-embedded organoids or cells after demolding, and transferring the agarose pre-embedded organoids or cells to an embedding box, and sequentially performing ethanol gradient dehydration, transparent treatment and paraffin wax immersion treatment on the sample according to a specific procedure; and 5) paraffin embedding. Compared with the prior art, the application has the following beneficial effects: improving organoid / cell density; by agarose embedding, reducing the relative dispersion volume of organoids / cells, significantly improving the density of the sample in the slice, facilitating observation and detection, and having good detection effect.

The application discloses a dielectric breakdown field strength and temperature dependence simulation method and system, and the simulation method comprises the following steps: establishing a criterion for polymer damage caused by molecular chain slip under the action of heat based on a free volume theory; establishing a breakdown criterion for polymer damage caused by molecular chain slip under the joint action of an electric field and a thermal field; quantifying the serpentine movement of a molecular chain under the action of a strong force; establishing an approximate analytical expression of polymer breakdown strength; and fitting the experimental results of sample breakdown field strength change with temperature according to the analytical expression by using a Curve fitting tool of Matlab. The breakdown model established from the perspective of molecular chain displacement can well explain the change relationship between the polymer nanocomposite dielectric breakdown field strength and temperature, and provides theoretical guidance for the preparation of high-temperature dielectric materials.

The utility model relates to the field of pesticide residue treatment, specifically is a kind of integrated agricultural product pesticide residue crushing extraction equipment, including extraction cylinder, the inside of extraction cylinder is sequentially opened with crushing chamber, control chamber and stirring chamber from top to bottom, heating unit is fixedly arranged on extraction cylinder and is matched with stirring chamber, the side portion of extraction cylinder is provided with centrifuge, and the bottom end of stirring chamber is communicated with centrifuge;The integrated agricultural product pesticide residue crushing extraction equipment of the utility model integrates multiple functions such as crushing, stirring, heating, centrifugal separation in one, realizes the full-process automation operation from agricultural product feed to residue extraction, separation, reduces the connection and transmission steps between multiple devices in traditional equipment, improves work efficiency, saves space.

This invention relates to a variable-order, variable-capacity water tank. The technical problem this invention aims to solve is to provide a nonlinear, multi-purpose water tank with variable order and variable capacity. The technical solution adopted by this invention includes a water tank body, a sealing plate, a first insert plate, a second insert plate, and a third insert plate. The water tank body includes a bottom plate and a tank casing. The tank casing is divided into a first inlet chamber, a first outlet chamber, an overflow chamber, a second outlet chamber, a second inlet chamber, a first working chamber, a second working chamber, and a third working chamber by a water tank partition. Water passage holes are provided between the first inlet chamber and the first working chamber, and between the second inlet chamber and the third working chamber. The advantages of this invention are: the water tank structure is ingeniously designed, allowing for variable capacity and variable order, enabling the construction of mathematical models of various orders; the structure of the sealing plate and insert plates replaces the traditional manual valve structure, exhibiting more significant nonlinear characteristics, enabling the system to stabilize quickly, shortening experimental time, and increasing the controllable range.

The utility model discloses a kind of BNCT mouse irradiation devices without anesthesia, including disc body, sliding assembly is installed on disc body, detachably installed with mouse fixer on sliding assembly, mouse fixer includes head fixing assembly and tail fixing assembly for limiting mouse activity, fixed shaft is vertically arranged on disc body, bracket is installed on fixed shaft, the end portion of bracket is located above mouse fixer and is provided with reversible folding connecting plate. Mouse head and neck are fixed by the fastening screw of mouse fixer, mouse tail is fixed by clamping groove, mouse can be irradiated subsequently without anesthesia, avoid anesthetics to influence BNCT treatment effect;By round multi-arm sliding rail clamping disc, multiple mouse fixers can be assembled, one mouse is placed in each fixer, reasonably divide area, avoid multiple mice confusion;By adjusting the position of mouse fixer on sliding rail and turning L-shaped connecting plate, multiple mice can be irradiated at different parts simultaneously, convenient operation, save experimental time.

The utility model belongs to the field of atom inertia measurement, and particularly discloses an auxiliary device for evaluating the Coriolis force of an atom interferometer, the auxiliary device comprises a lifting rotation supporting module and an inclination detection adjusting module, and the inclination detection adjusting module comprises an inclination detection unit and an inclination adjusting unit; the inclination detection unit is used for detecting the inclination of the vacuum container; the inclination adjusting unit is located at the bottom of the vacuum container and used for supporting the vacuum container and adjusting the vacuum container to be horizontal according to the inclination. The lifting rotation supporting module can be coaxially arranged under a vacuum container of the atom interferometer and can drive the vacuum container to rotate so as to modulate the Coriolis force. According to the invention, the effect of rotating the vacuum container in the atom interferometer with high efficiency and high precision can be realized.

The present application relates to dilution refrigerator temperature calibration technical field, and disclose a kind of dilution refrigerator thermometer in situ calibration system based on natural cooling dynamics, comprising: according to the dynamics equation of cooling power and temperature Curvature is calculated, according to the temperature corresponding to thermometer resistance value, the temperature is substituted into temperature curvature, and the calibration function of resistance value and temperature is obtained;Identify the multivalued region of temperature, and evolve multiple branch functions in multivalued region in calibration function, calculate the deviation measure of each branch function and calibration function;In multivalued region, the support degree of each branch function to calibration function is calculated, and real-time data is obtained by adjusting calculation load, to minimize the number of experiments to verify calibration function;According to the branch verification result of multivalued region, dynamically adjust the verification strategy of non-multivalued region, under the premise of not relaxing calibration accuracy, through dynamics branch and load guide, significantly reduce the repeated experiment cost of dilution refrigerator cryogenic calibration.

This utility model relates to the field of anti-icing coating testing technology, and provides an anti-icing coating testing device using rapid cooling with liquid carbon dioxide. The device includes an aluminum substrate, an aluminum vaporization grid, and a test sample. The test sample is positioned on the top of the aluminum substrate, and the aluminum vaporization grid is positioned on the bottom of the aluminum substrate. A liquid carbon dioxide inlet is located in the middle of the left side of the aluminum vaporization grid, and a carbon dioxide outlet is located in the middle of the right side of the aluminum vaporization grid. This utility model utilizes the principle of heat absorption during liquid carbon dioxide vaporization to rapidly reduce the temperature of the aluminum substrate in a short time, quickly simulating the icing / icing phenomenon under actual extreme low-temperature environments. Compared to traditional testing methods, this significantly shortens the testing cycle, allowing for rapid testing of the anti-icing coating performance, effectively improving testing efficiency, and saving considerable time and costs for research and development and production. Simultaneously, the realistic simulation of extreme environments enhances the practicality and reference value of the test results.

The invention belongs to the field of high-molecular polymers, and relates to a multichannel confocal rapid phase diagram instrument, application and a polymer solution system phase diagram drawing method. The multichannel confocal rapid phase diagram instrument comprises the following components which are arranged in sequence: a laser light source, a laser beam expander, a first lens, a multichannel precise temperature control sample cell system and a detection system, wherein the detection system comprises a small-angle confocal diode detection system; the small-angle confocal diode detection system comprises a second lens with a first collimation system and a photodiode with a second collimation system, and the first lens and the second lens form a double-lens 2f-2f confocal optical system. According to the device and the method, the phase transition rule of a plurality of polymer solution systems in the heating process can be monitored at the same time, and theoretical guidance and regulation and control basis are provided for regulating and controlling the structure or performance of macromolecules by regulating the properties, the phase transition, the temperature and the like of a solvent in the solution polymerization process and the solution processing process.

The invention discloses a cell culture medium configuration optimization method, device and equipment and a storage medium, and the method comprises the following steps: training a target agent model based on a current component data set to obtain a current prediction model, and determining a current component collection function; acquiring a target component configuration space based on the current component acquisition function to obtain multiple pieces of second component configuration information; based on the current component data set, the second component configuration information and a second experiment result corresponding to each piece of second component configuration information, determining a to-be-selected component data set obtained by the current optimization; adding the to-be-selected component data set obtained by the current optimization into the current component data set, and returning to execute the operation of training the target agent model based on the training data; and the optimal target component data set meeting the preset convergence condition is obtained. Through the technical scheme of the embodiment of the invention, comprehensive and efficient optimization of the cell culture medium is realized, so that the optimization degree and efficiency of the cell culture medium are improved.

The application discloses a CALPHAD-based cross-system knowledge transfer alloy design method, which comprises the following steps: performing CALPHAD balance calculation on a source aluminum alloy and a target Al-Mg-Zn alloy to construct an initial feature set; deriving mean value and variance of phase fraction weighting and multi-step heat treatment addition / difference features; locking an optimal feature subset through three-step feature selection assisted by source data set; training 300 base models through bagging, integrating mean value and standard deviation to obtain a high-stability predictor; and coupling NSGA-II and high-throughput CALPHAD to search for a Pareto frontier with double targets of strength and elongation and determine a composition-process scheme; and the application significantly improves the model interpretability and generalization performance by constructing a CALPHAD descriptor with physical interpretability as a model feature, thereby improving the alloy design efficiency and reducing the experimental workload.

The invention discloses an automatic sample liquid suction and injection filtering mechanism which comprises a supporting bottom plate, a supporting clamping frame is arranged on the front portion of the upper end face of the supporting bottom plate, and a reagent bottle containing tool is arranged on the side portion of the upper end face of the supporting clamping frame. When the device is used, the precision reliability is high, meanwhile, the consistency of experimental data is improved by at least 90%, the batch processing efficiency can be effectively improved, batch manufacturing can be achieved in batches, the experimental time is greatly saved, meanwhile, automatic operation can be achieved, cross contamination control can be greatly avoided, full-automatic operation can be achieved, 80% of repeated operation can be reduced, and the working efficiency is improved. The mechanical physical isolation of dangerous liquid enables safety accidents to be close to zero, can promote the overall automation rate of a laboratory to be improved by 30%-50%, and supports efficient and compliant operation of biological medicine, environmental monitoring and new material research and development.

The application discloses a space flexible truss vibration control experimental system based on a liquid-electric hybrid actuator, comprising: a single machine performance test platform of the liquid-electric hybrid actuator, which is used for verifying the static output force characteristics, positioning characteristics and driving frequency response characteristics of the liquid-electric hybrid actuator under the open-loop no-load condition; a one-dimensional vibration isolation test platform of the liquid-electric hybrid actuator, which is used for verifying the active-passive integrated one-dimensional broadband vibration isolation effect of the liquid-electric hybrid actuator under the variable load condition; and a flexible truss vibration control ground test platform based on the liquid-electric hybrid actuator, which is used for measuring the influence law of the flexible truss dynamic response and controlling the output of the liquid-electric hybrid actuator. The application can reflect the influence law of the hinge nonlinearity and geometric nonlinearity on the flexible truss dynamic response on one hand, and can verify and compare the effectiveness and practicability of the online vibration active control algorithm of the flexible truss structure on the other hand.

This invention provides a TIR spacer sequence optimization method based on guided active learning, belonging to the field of synthetic biology. The method includes: Step 1: Constructing an initial seed bank containing multiple samples; Step 2: Extracting multidimensional biophysical features from each sample; Step 3: Training a primary regression model based on a training ensemble model based on the multidimensional biophysical features; Step 4: Performing guided iteration on the algorithm of the primary regression model; Step 5: In each round of guided iteration, using a SHAP model to analyze features as navigation for the guided exploration strategy, selecting samples with high exploration value for experimental verification, and incorporating the feedback data from the experimental verification into the training set in real time to update the model parameters; Step 6: Continuing guided iteration on the model with updated parameters, repeating Step 5 until the model converges or reaches the predetermined optimization objective. This invention achieves local landscape reshaping with a small sample size.

This invention discloses a rapid determination device and method for the dynamic formation temperature of high-pressure hydrates, relating to the field of oil and gas extraction technology. The determination device includes: a reaction vessel system comprising a high-low temperature alternating test chamber employing nonlinear cooling and a high-pressure reaction vessel located within the test chamber; a stirring system located within the test chamber, which uses magnetic coupling to stir the experimental fluid within the high-pressure reaction vessel; a sample preparation system for preparing samples for the experiment; and an observation system for observing the experiment inside the high-pressure reaction vessel. This invention provides an accurate determination of the hydrate formation temperature of water-producing oil and gas wells and surface pipelines under different pressures, flow rates, and surface roughnesses. By fitting experimental data, an empirical formula for hydrate formation considering pressure, fluid flow rate, and surface roughness factors is obtained, providing technical support for hydrate prevention and control and ensuring oil and gas field supply during winter.

The application provides a vanadium oxide wet extraction expansion test platform oil bath heating method and relates to the field of wet vanadium extraction oil bath heating model algorithm, and comprises the following steps: opening a heater, heating conductive oil to a limit temperature T e , the limit temperature T e is greater than a set temperature T s ; when real-time oil temperature T o is greater than T e , the heater is turned off, the conductive oil continues to circulate and exchange heat with a reaction kettle through an oil pump; in the heat exchange process, reaction temperature T n rises, and real-time oil temperature T O falls; finally, real-time oil temperature T o and reaction temperature T n reach equilibrium; then, the reaction temperature is kept constant through an oil temperature machine control. In the oil bath heating process of improving the vanadium oxide wet extraction expansion test platform leaching process, the application improves the reaction material heating speed in the reaction kettle, and the reaction temperature is raised to the target temperature in the shortest time.

The invention relates to the technical field of electrical experiments, and provides a flashover experiment device and method for an insulating material, and the device comprises a metal tank which can be filled with an insulating gas; the pressurizing end of the pressurizing assembly is located in the metal can body; a bearing table of the bearing assembly is located in the metal tank body, and the bearing table for bearing the target sample can move relative to the metal tank body so as to be close to or away from the pressurizing end; the measuring end of the potential measuring assembly is located in the metal tank body, and the measuring end is used for measuring the potential of the target sample; the regulation and control end of the humidity control assembly is located in the metal tank body, and the regulation and control end is used for measuring and / or regulating the humidity in the metal tank body; and the grounding assembly is electrically connected with the metal tank body. According to the flashover experiment device, flashover experiments can be carried out on the insulating material under different humidity conditions, so that the influence of the humidity conditions on the insulating property of the insulating material is researched.

The utility model relates to a kind of multifunctional paraffin prevention experimental device, including base, outer tube, limiting cylinder, wax pipe, temperature sensor and motor;The wax pipe is placed in limiting cylinder, and the outer tube bottom end is fixed on base, multiple limiting cylinders are set in outer tube inside at equal intervals, temperature sensor and heating coil are installed in each limiting cylinder, the temperature sensor is embedded on the limiting cylinder inner wall, and the heating coil is evenly arranged on the limiting cylinder inner wall;Rotary piece is provided at the bottom of limiting cylinder, and the motor is set in the base inside below rotary piece, and the transmission shaft of motor is fixedly connected with rotary piece.The utility model relates to multifunctional paraffin prevention experimental device can be used for exhibition wax influencing factor analysis and paraffin prevention experiment.

The application discloses a kind of insulin secretion detection method based on trace system continuous stimulation, which includes sequentially in the same microchamber low sugar, high sugar, Exendin-4 and KCl continuous stimulation, collection supernatant, lysis detection total insulin and standardization analysis.The method of the application uses trace system, low sample consumption, continuous sequential stimulation design, significantly reduces sample and reagent consumption, eliminates group difference, improves detection sensitivity and repeatability, especially suitable for limited sample source, higher culture cost or need to carry out high-throughput functional analysis research scene, including stem cell differentiation optimization, drug screening, diabetes mechanism research and islet transplantation quality control etc., with good application prospect and popularization value.The method of the application is also suitable for the insulin secretion of other species primary islets and islet-like cell clusters, and the detection of other endocrine hormones (such as glucagon, somatostatin, etc.).

The application belongs to the technical field of organic chemistry, and provides a separation method for free long straight chain fatty acids in geological samples, which comprises the following steps: S1, crushing a geological sample, and performing Soxhlet extraction treatment to obtain organic matter in the geological sample; S2, centrifugally separating the total organic matter extracted in the step S1 to remove asphaltene; S3, adding 1ml of n-hexane to dissolve the organic matter in the centrifugal liquid obtained after the centrifugal separation in the step S2, performing component separation by filling column chromatography and elution with different solvent components to obtain a polar component; the separation method adopted by the application is fast and efficient, and the conventional Soxhlet extraction process can directly methyl esterize the long straight chain fatty acids, thereby avoiding the conventional and tedious saponification, acidification and methyl esterization experiments, and greatly shortening the experimental time and cost.

The present application relates to a kind of experimental methods based on microfluidic test gas-liquid diffusion distance and diffusion coefficient.The experimental device is composed of microfluidic chip, microfluidic chip holder, 4 opening high temperature and high pressure micro reaction kettle, trace displacement pump, back pressure constant pressure pump, back pressure valve, intermediate container, temperature control box, image acquisition device and the like.The method comprises the following steps: (1) establishing corresponding simulation porous medium model; (2) configuring sample; (3) connecting experimental device and leak detection; (4) pre-saturation crude oil; (5) adjusting temperature to formation temperature; (6) establishing system pressure to formation pressure; (7) simulating micro diffusion experiment, and recording diffusion condition in real time; (8) after experiment, unloading pressure; (9) using image processing software to determine diffusion distance by observing color change of crude oil; (10) using diffusion distance to calculate diffusion coefficient.The present application is convenient and fast, and the result is accurate and reliable, which provides theoretical guidance and technical support for improving recovery efficiency.

The utility model discloses a multi-position linkage type laboratory suction filtration device which comprises a fixed frame and a disc clamp, four liquid collecting bottles are arranged on the fixed frame, a fixed column is arranged at the center of the fixed frame, an exhaust pipe is arranged on the fixed column, and the exhaust pipe is connected with a vacuum pump; the disc clamp comprises an upper disc clamp and a lower disc clamp, four filter cups are arranged in the upper disc clamp, four filter heads are arranged in the lower disc clamp, the bottoms of the four filter cups are connected with the tops of the four filter heads, and the bottoms of the four filter heads are connected with the liquid collection bottle; the liquid collecting bottle is connected with the exhaust pipe. Four independent suction filtration devices are communicated through a vacuum pump and an exhaust pipe, so that simultaneous work is realized, and the suction filtration speed is obviously increased; the movable clamp can be switched between the upper exhaust pipe and the lower exhaust pipe, so that the suction filtration and the disassembly flow are seamlessly connected, and the single operation time is shortened; according to the suction filtration device, the traditional decentralized operation is integrated into a coherent process through the design of parallel multiple instruments, rapid paper replacement, air exchange linkage and the like, so that the time consumption of a single experiment is remarkably reduced, and the suction filtration device is suitable for high-throughput or repeated suction filtration requirements.

This invention relates to the field of automotive testing technology, specifically to a biomechanical performance simulation module and measurement method for a human-like ribcage. It includes a fixed support, rib units, and an arm unit. The fixed support comprises a shoulder support and a chest support, both fixedly connected to the rib units. The rib units include inner ribs, outer ribs, and displacement sensors. An inner layer pad is located at the center of the inner side of the inner ribs, and the outer ribs are semi-open rings with an outer layer pad located at the center of their outer side. The inner and outer pads are fixedly connected by screws. Openings are provided along the centerlines of the inner ribs, outer ribs, inner pads, and outer pads. One end of the displacement sensor is fixedly connected to the chest support, and the other end is fixed in the opening via a pin. An arm connecting block is fixedly connected to the outer side of the rib unit at the shoulder support, and is fixedly connected to the arm unit. This solution can more accurately simulate and evaluate the damage to a pedestrian's chest in a side-impact accident.

The embodiment of the utility model provides a multichannel nerve stimulation device which is used for medical animal experiments and belongs to the technical field of nerve stimulation. The multichannel nerve stimulation device comprises a stimulation unit which comprises at least two stimulation parts, and the at least two stimulation parts are connected with a driving system used for providing stimulation energy; the fixing part is provided with at least two fixing positions according to a preset arrangement rule, and the stimulation parts are fixed on the fixing positions; the sample placing unit comprises at least two sample placing parts which are arranged corresponding to the at least two stimulation parts and are used for placing experimental animal samples; one end of the adjusting unit is connected with the fixing part, and the other end of the adjusting unit is connected with the sample placing unit. According to the multichannel nerve stimulation device, true nerve stimulation and / or pseudo nerve stimulation can be carried out on a plurality of experimental animal samples at the same time, and the experimental efficiency is improved.