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Cell chip slide for preparing microarray cell chips and preparation method

A technology of cell chips and microarrays, applied in biochemical equipment and methods, specific-purpose bioreactors/fermenters, enzymology/microbiology devices, etc., to achieve the effects of simple preparation, simple device structure, and simple operation steps

Inactive Publication Date: 2012-10-10
XI AN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be seen that there are still the above-mentioned defects in the preparation of microarray cell chips by the existing technology.

Method used

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  • Cell chip slide for preparing microarray cell chips and preparation method
  • Cell chip slide for preparing microarray cell chips and preparation method
  • Cell chip slide for preparing microarray cell chips and preparation method

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Comparison scheme
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Embodiment Construction

[0053] The present invention will be further described in detail below in conjunction with specific embodiments, which are explanations of the present invention rather than limitations.

[0054] see Figure 1 ~ Figure 3 A cell chip base for preparing a microarray cell chip, comprising a substrate 1 and a sealing cover 2, the substrate 1 is provided with array holes 4 distributed in an array, and the bottoms of the array holes 4 are transparent and located on the same horizontal plane;

[0055] The sealing cover 2 is provided with hollow array posts 5 matching the array holes 4 of the substrate 1 , the array posts 5 can extend into the corresponding array holes 4 , and the bottoms of the array posts 5 are transparent and located on the same horizontal plane. The depths of the array holes are all the same, and the heights of the array columns are also all the same.

[0056] The array well 4 of the substrate 1 is mainly used for culturing cells, and the cells adhere to the botto...

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Abstract

The invention discloses a cell chip slide for preparing microarray cell chips. The cell chip slide comprises a substrate and a sealing cover, the substrate is provided with array holes distributed in an array manner, the bottoms of the array holes are transparent and positioned on the same horizontal plane, the sealing cover is provided with hollow array posts matching with the array holes of the substrate, the array posts can extend into corresponding array holes, and the bottoms of the array posts are transparent and positioned on the same horizontal plane. The cell chip slide is simple in structure, easy to prepare and convenient to use, and can comprise various (numerous) cells arrayed in a regular array manner, therefore, detection or experimental studies of same or different indexes can be performed for various (numerous) cells simultaneously once. By the aid of the cell chip slide, operation steps are simple, and detection or experimental studies can be completed once.

Description

technical field [0001] The invention belongs to the technical field of cell chips, and relates to a cell chip base for preparing microarray cell chips and a preparation method. Background technique [0002] Biochip technology, also known as biological microarray technology, refers to immobilizing a large number of molecules (genes, proteins, tissues, cells, etc.) The hybridization signal strength of the needle molecule can be used to obtain the quantity and sequence information of the sample molecule, so as to realize the accurate, rapid and large-scale detection of cells, proteins, genes and other biological components. It has incomparable advantages over other traditional methods and has been widely used in life science research and medical diagnosis, mainly including gene chip, protein chip (including antibody chip, antigen chip), tissue chip and cell chip, etc. [0003] Among them, cell chip is a kind of biochip technology with cells as the research object. It is an imp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00C40B50/06
CPCC12M23/22C12M23/38C12M23/12
Inventor 杨军张明娟康安静刘妮李宗芳苏宝山陈晓黎
Owner XI AN JIAOTONG UNIV
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