Traditional Chinese medicine compound composition capable of treating infantile constipation as well as preparation method and application thereof

A composition and constipation technology, applied in the field of traditional Chinese medicine, can solve the problems of unsuitable for long-term use of children, drug toxicity, low treatment cost, etc., achieve the effect of reducing serum SS, weak toxic and side effects, and convenient clinical use

Inactive Publication Date: 2018-06-15
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, chemical drugs and Chinese patent medicines are generally used in drug treatment. Chemical drugs are effective quickly, but they cannot cure the disease. The curative effect of long-term use gradually decreases, and the treatment cost is high; Chinese medicine treatment can treat both symptoms and root causes, safe and effective, and the treatment cost is relatively low
Although there are several medicines for treating this disease on the market at present, such as Wangshi Baochi Pills, they do not specifically treat constipation, and some of them (croton, cinnabar, and araceae) are toxic and are not suitable for children to take for a long time; Intestinal heat and body fluid deficiency, not the common syndrome of food accumulation and internal heat in children with constipation

Method used

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  • Traditional Chinese medicine compound composition capable of treating infantile constipation as well as preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0035] 1. A traditional Chinese medicine compound composition with the effect of treating infantile constipation, which is made of the following raw materials:

[0036] 9 parts of Citrus aurantium, 12 parts of Magnolia officinalis, 9 parts of Trichosanthes, 9 parts of Forsythia, 12 parts of Liu Shenqu, 9 parts of Stir-Fried Cassia Seeds, 3 parts of Rhubarb, 6 parts of Gallus gallus domesticus.

[0037] 2. The preparation method of the Chinese medicine compound composition with the effect of treating infantile constipation includes the following steps:

[0038] (1) Take 9 parts of Citrus aurantium, 12 parts of Magnolia officinalis, 9 parts of Trichosanthes, 9 parts of Forsythia, 12 parts of Liu Shenqu, 9 parts of Stir-Fried Cassia Seeds, 6 parts of Gallus gallus domesticus, put them in the extractor, add the weight of Chinese herbal medicine first Soak 12 times the volume of water for 30 minutes, then heat and extract for 2 hours, filter and add 8 times the volume of water to extract ...

Embodiment 2

[0042] 1. A traditional Chinese medicine compound composition with the effect of treating infantile constipation, which is made of the following raw materials:

[0043] Citrus aurantium 12 parts, Magnolia officinalis 15 parts, Trichosanthes 12 parts, Forsythia 12 parts, Liu Shenqu 15 parts, Stir-fried Cassia seeds 12 parts, Rhubarb 5 parts, Gallus gallus domesticus 7.5 parts.

[0044] 2. The preparation method of the Chinese medicine compound composition with the effect of treating infantile constipation includes the following steps:

[0045] (1) Take 12 parts of Citrus aurantium, 15 parts of Magnolia officinalis, 12 parts of Trichosanthes, 12 parts of Forsythia, 15 parts of Liu Shenqu, 12 parts of Stir-Fried Cassia Seeds, 7.5 parts of Gallus gallus domesticus, put them in the extractor, and add the weight of Chinese herbal medicine first Soak 10 times the volume of water for 30 minutes, then heat and extract for 1 hour, filter and add 6 times the volume of water to extract for 1 hou...

Embodiment 3

[0049] 1. A traditional Chinese medicine compound composition with the effect of treating infantile constipation, which is made of the following raw materials:

[0050] Citrus aurantium 6 parts, Magnolia officinalis 6 parts, Trichosanthes 6 parts, Forsythia 6 parts, Liu Shenqu 6 parts, Stir-fried Cassia seeds 6 parts, Rhubarb 3 parts, Gallus gallus domesticus 3 parts.

[0051] 2. The preparation method of the Chinese medicine compound composition with the effect of treating infantile constipation includes the following steps:

[0052] (1) Take 6 parts of Citrus aurantium, 6 parts of Magnolia officinalis, 6 parts of Trichosanthes, 6 parts of Forsythia, 6 parts of Liushenqu, 6 parts of Stir-Fried Cassia Seeds, 3 parts of Gallus gallus domesticus, put them in the extractor, add the weight of Chinese herbal medicine first Soak in 8 times the volume of water for 30 minutes, then heat and extract for 1.5 hours, filter and add 8 times the volume of water to extract for 1.5 hours, filter, co...

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Abstract

The invention discloses a traditional Chinese medicine compound composition capable of treating infantile constipation and a preparation method thereof. The traditional Chinese medicine compound composition is prepared from 6-15 parts of immature bitter orange, 6-15 parts of magnolia officinalis, 6-15 parts of snakegourd root, 6-15 parts of fructus forsythiae, 6-15 parts of medicated leaven, 6-15parts of fried cassia seed, 3-5 parts of rhubarb, and 3-9 parts of chicken's gizzard-membrane. The traditional Chinese medicine compound composition provided by the invention provides treatment according to differentiation of symptoms and signs on the basis of the theory of traditional Chinese medicine and has a scientific prescription according to the pathogenesis of infantile constipation; and experimental research results prove that the traditional Chinese medicine compound composition provided by the invention has scientific and reasonable proportion of each component, can obviously improve the activity of pepsin in rats, has a promoting effect on a propulsion function of small intestines in mice, and can reduce serum SS of the mice, and increase MTL and GAS, thereby regulating gastrointestinal hormones and promoting gastrointestinal peristalsis. Moreover, clinical experimental results show that the traditional Chinese medicine compound composition has a very good therapeutic effect on infantile constipation, and has good safety and no toxic or side effects.

Description

Technical field [0001] The present invention relates to a traditional Chinese medicine compound prescription, in particular to a traditional Chinese medicine compound compound composition with the effect of treating infantile constipation and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Functional Constipation (FC) in children is one of the most common digestive disorders in children. Constipation in children will seriously affect children's growth and development, physical and mental health, and quality of life. It can often lead to loss of appetite, even anorexia, slow thinking, and decreased memory. The domestic epidemiological survey showed that the incidence of functional constipation in children was 3.8%, with more girls than boys, and more cities than rural areas. At present, Western medicine is not very clear about the etiology and pathogenesis of children's functional cons...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P1/10A61K35/57
CPCA61K36/752A61K35/57A61K36/00A61K36/428A61K36/482A61K36/575A61K36/634A61K36/708A61K2236/331A61K2236/39A61K2300/00
Inventor 赵霞刘志辉周涛
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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