Chinese herbal compound composition with function of treating constipation as well as preparation method and application thereof

A technology for treating constipation and composition, applied in the directions of drug combination, medical preparation containing active ingredients, pharmaceutical formula, etc. Small intestine propulsion and emptying movement, small adverse effects on the body, and the effect of promoting gastrointestinal motility

Inactive Publication Date: 2014-06-25
NANJING DRUM TOWER HOSPITAL +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] ① General treatment: rely on changing lifestyle, increasing exercise and dietary fiber, but little effect on intractable constipation, need to cooperate with drug treatment
And these laxatives can cause benign reversible colonic pigmentation, long-term use can damage the enteric nervous system, lead to intestinal motility disorders, and form slow transit constipation in the colon

Method used

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  • Chinese herbal compound composition with function of treating constipation as well as preparation method and application thereof
  • Chinese herbal compound composition with function of treating constipation as well as preparation method and application thereof
  • Chinese herbal compound composition with function of treating constipation as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] 1, a kind of Chinese medicine compound composition with the effect of treating constipation, it is made of the raw material of following weight:

[0039] Atractylodes macrocephala 30g, Scrophulariaceae 20g, Ophiopogon japonicus 20g, Citrus aurantium 10g, Magnolia officinalis 15g, Almond 10g, Hemp seed 15g, Trichosanthes 15g.

[0040] 2. The preparation method of the Chinese medicine compound composition having the effect of treating constipation, comprising the following steps:

[0041] (1) Take 30g of Atractylodes macrocephala, 20g of Scrophulariae, 20g of Ophiopogon japonicus, 10g of Citrus aurantii, 15g of Magnolia officinalis, 10g of almond, 15g of hemp seed, 15g of Trichosanthes semen, add water to decoct twice, and add up the medicinal materials 10 times for the first time Measure water, decoct for 1 hour, add 8 times the amount of medicinal materials for the second time, decoct for 0.5 hour, combine the second decoction, filter, let the filtrate stand for 24 hour...

Embodiment 2

[0044] 1, a kind of Chinese medicine compound composition with the effect of treating constipation, it is made of the raw material of following weight:

[0045] Atractylodes macrocephala 20g, Scrophulariaceae 15g, Ophiopogon japonicus 15g, Citrus aurantium 5g, Magnolia officinalis 10g, Almond 5g, Hemp seed 10g, Trichosanthes 10g.

[0046] 2. The preparation method of the Chinese medicine compound composition having the effect of treating constipation, comprising the following steps:

[0047] (1) Take 20g of Atractylodes macrocephala, 15g of Scrophulariae, 15g of Ophiopogon japonicus, 5g of Citrus aurantii, 10g of Magnolia officinalis, 5g of almond, 10g of hemp seed, 10g of Trichosanthes semen, add water to decoct twice, and add up to 10g of medicinal materials for the first time. Double the amount of water, decoct for 2 hours, add up to 8 times the amount of medicinal materials for the second time and decoct for 1 hour, combine the second decoction, filter, let the filtrate st...

Embodiment 3

[0051] 1, a kind of Chinese medicine compound composition with the effect of treating constipation, it is made of the raw material of following weight:

[0052] Atractylodes macrocephala 25g, Scrophulariaceae 18g, Ophiopogon japonicus 18g, Citrus aurantium 8g, Magnolia officinalis 12g, Almond 8g, Hemp seed 12g, Trichosanthes 12g.

[0053] 2. The preparation method of the Chinese medicine compound composition having the effect of treating constipation, comprising the following steps:

[0054] (1) Take 25g of Atractylodes macrocephala, 18g of Scrophulariae Radix, 18g of Ophiopogon japonicus, 8g of Citrus aurantium, 12g of Magnolia officinalis, 8g of almond, 12g of hemp seed, 12g of Trichosanthes semen, add water to decoct twice, and add up the medicinal materials 10 times for the first time Measure water, decoct for 2 hours, add 8 times the amount of medicinal materials for the second time, decoct for 2 hours, combine the second decoction, filter, let the filtrate stand for 24 h...

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Abstract

The invention discloses a Chinese herbal compound composition with a function of treating constipation and a preparation method thereof. The Chinese herbal compound composition is prepared from the following raw materials in parts by weight: 20-30 parts of atractylodes macrocephala, 15-20 parts of figwort root, 15-20 parts of dwarf lilyturf tuber, 5-10 parts of immature bitter orange, 10-15 parts of officinal magnolia bark, 5-10 parts of almonds, 10-15 parts of hemp seed and 10-15 parts of snake gourd seed. The Chinese herbal compound composition and the preparation method have the advantages that treatment based on syndrome differentiation is carried out according to the theory of the traditional Chinese medicine; scientific composition is carried out according to the pathogenesis of constipation; experimental study results prove that the Chinese herbal compound composition can excite smooth muscles of intestinal canals, increase the muscle tones, promote gastrointestinal motility and obviously increase the contraction amplitude, not only has the obvious functions of promoting small intestine movement and accelerating gastric emptying but also has the obvious functions of reducing the defecating time and increasing the defecating frequency. Therefore, the Chinese herbal compound composition provided by the invention is expected to be developed into a new-generation safe and effective new medicine for treating constipation.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine, in particular to a compound traditional Chinese medicine composition capable of treating constipation, a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine preparations. Background technique [0002] Chronic functional constipation is a common clinical disease. With the development of a series of factors such as the increase of people's life pressure, the acceleration of rhythm, and the change of diet, its incidence rate is showing an upward trend year by year. Although no systematic and comprehensive epidemiological investigation has been seen at present, according to previous epidemiological investigations, 14.7% of people in the world are suffering from constipation, and the incidence rate in my country is 10%-15%. Elderly people account for 18% to 23%, and the age of onset tends to be younger in recent years, especially in wo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P1/10
Inventor 徐天舒钱海华
Owner NANJING DRUM TOWER HOSPITAL
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