The invention discloses a mass spectrometry ion extraction device and method. The mass spectrometry ion extraction device comprises an ion source, an air curtain cavity, a sampling cavity and an ion optical assembly which are sequentially arranged, wherein the ion source is used for generating ions of an object to be detected; the inlet end of the air curtain cavity is composed of a conical air curtain plate with an air curtain hole, the side wall of the air curtain cavity is provided with a branch for providing air curtain air, a strong focusing electrode assembly is arranged in the air curtain cavity, and a slit is formed between one end, close to the air curtain hole, of the strong focusing electrode assembly and the inner wall of the air curtain plate; the sampling cavity comprises a sampling cone and a high-pressure ion transmission assembly, and a second differential hole is formed in the outlet end of the sampling cavity. According to the invention, the extraction interface is improved, the distance between the air curtain hole and the sampling cone is increased, ions extracted by the air curtain hole are focused by applying a spatial strong focusing electrostatic quadrupole electric field, and the density of an ion group is improved, so that the extraction efficiency of the sampling cone is improved, and the concentration of a solvent ion adduct is reduced.