35 results about "Vascular lumen" patented technology

The utility model discloses a multifunctional dressing for an interventional operation. The medical instrument aims to solve the technical problem that in the prior art, pressure injury is easily caused to the skin on the face when an oxygen inhalation tube is used for a long time. The medical instrument comprises a dressing body, the dressing body is arranged in a long strip shape, an arc-shaped groove is formed in the middle of the top end of the dressing body, a first implantation piece and a second implantation piece are arranged in the dressing body and located at the left end and the right end of the lower portion of the arc-shaped groove respectively, and auxiliary parts are arranged in the middles of the two ends of the dressing body; the medical dressing is easy and convenient to operate and high in practicability, and the dressing body made of polyurethane foam is comfortable to use due to the vertical foaming technology, good in air permeability, capable of reducing pressure and protecting, free of pain in stripping and capable of being pasted repeatedly. The first implantation piece and the second implantation piece which are made of stainless steel and are different in size are placed in the middle of the dressing body, development is carried out under X rays, and the size of a blood vessel cavity can be evaluated conveniently.

Embodiments of the present application provide a blood vessel detection system, an electronic device, a storage medium and a computer program product. The system comprises a catheter and a host. The catheter is provided with a first signal collector and a second signal collector. The first signal collector is used to collect intravascular ultrasound echo signals, and the second signal collector is used to collect blood flow source signals. The host is used to generate an intravascular ultrasound image according to the intravascular ultrasound echo signals of a blood vessel to be detected, determine blood flow information of the blood vessel to be detected according to the blood flow source signals of the blood vessel to be detected, register the intravascular ultrasound image and the blood flow information in the collection time, determine first blood flow information matched by a first intravascular ultrasound image when a blood vessel lumen reaches a maximum expansion state and second blood flow information matched by a second intravascular ultrasound image when the blood vessel lumen is in a resting state according to a registration result, and calculate a blood flow reserve characteristic value according to the determined blood flow information. In this way, comprehensive evaluation of blood vessel morphology and function can be achieved.

This application discloses a restraint balloon, its preparation method, and a balloon catheter, relating to the field of medical devices. The restraint balloon includes: an expandable balloon body; and a restraint component, composed of fibrous strands and fixed to the outer surface of the balloon body, used to limit the radial deformation of the balloon body during expansion. The restraint balloon of this application can limit the radial deformation of the balloon body, effectively dispersing stress during expansion. It can be used for the clinical treatment of non-vascular lumen stenosis. Because the fibrous strand restraint component can deform synchronously with the balloon body during expansion, and can contract to a near-initial state along with the balloon body after decompression due to its own elastic recovery characteristics, it significantly reduces the difficulty of balloon retraction, improving the safety and convenience of surgical procedures. It also has the advantages of low cost, high yield, simple processing, and high manufacturing efficiency.

The invention relates to a manufacturing method of a bionic blood vessel model and the bionic blood vessel model.The manufacturing method of the bionic blood vessel model comprises the steps that a three-dimensional computer model of a blood vessel lumen is constructed according to blood vessel image data; according to a three-dimensional computer model of a blood vessel lumen, a water-soluble polyvinyl alcohol material is adopted to manufacture a water-soluble inner core through a 3D printing technology; the water-soluble inner core is subjected to operation for N times or less, wherein N is larger than or equal to 1; the outer surface of the water-soluble inner core is evenly covered with a polyvinyl alcohol solution; the water-soluble inner core covered with the polyvinyl alcohol solution is subjected to at least one time of freeze thawing treatment, so that the polyvinyl alcohol solution is solidified into polyvinyl alcohol hydrogel; after N times of operation are completed, the water-soluble inner core covered with the polyvinyl alcohol hydrogel is soaked in ultrapure water so that the water-soluble inner core can be dissolved, and therefore the bionic blood vessel model with the good shape and mechanical property is obtained.

A method and system for editing a lumen contour of a tomographic image. A method comprises: receiving image data corresponding to a plurality of tomographic images acquired by an imaging catheter scanning a blood vessel; obtaining, by a processor, an automatically-generated lumen contour of the blood vessel from a tomographic image of the blood vessel; displaying, on a display, the automatically-generated lumen contour overlaid on the tomographic image of the blood vessel; identifying a true lumen edge of the blood vessel in the tomographic image; estimating a percentage of matching between a shape of the automatically-generated lumen contour to a shape of the true lumen edge; and receiving editing operations from a user via a touchscreen interface for editing at least part of the automatically-generated lumen contour based on the estimated percentage of matching. Plural editing modes are available based on the percentage of matching meeting one or more thresholds.

The utility model discloses a tissue separation pad beneficial to microvascular anastomosis, which comprises a pad, an air cushion is arranged on the inner wall of the pad, a support is arranged in the air cushion, two suture pads are arranged above the pad, and the two suture pads can be attached to each other. The utility model relates to the technical field of vascular anastomosis, in particular to a tissue separation pad beneficial to microvascular anastomosis, which can play a role in physically separating tissues around a blood vessel from a lumen of the blood vessel through the matching of a gasket, an air cushion, a winding rope, a titanium alloy layer and a bracket, and provides a relatively pure anastomosis environment. In the process, some easily-coagulated substances, fat particles, vascular adventitia and other tissues are effectively prevented from entering a vascular lumen in the anastomosis process, vascular embolism is prevented, and the tissue separation pad beneficial to microvascular anastomosis can be expanded outwards all the time by means of the elasticity of the support, so that the tissue separation pad is more stable. And the phenomenon of vascular occlusion caused by extrusion of the tissue separation pad beneficial to microvascular anastomosis is avoided.

The invention discloses a blood vessel lumen diameter calibration method and device, equipment, a medium and a product, and the method comprises the steps: obtaining first-type blood vessel image data and second-type blood vessel image data of a first object, and the registration relation between the first-type blood vessel image data and the second-type blood vessel image data; according to the registration relationship, determining a diameter mapping relationship between the first type of blood vessel image data and the second type of blood vessel image data based on a first blood vessel diameter of the first type of blood vessel image frame and a second blood vessel diameter of the second type of blood vessel image frame; according to a diameter mapping relation, adjusting a blood vessel diameter corresponding to a blood vessel image frame in the first type of blood vessel image data to obtain a target intracavity blood vessel diameter; and mapping the target intracavity blood vessel diameter to the blood vessel diameter of the corresponding second type blood vessel image frame in the second type blood vessel image data. According to the technical scheme provided by the embodiment of the invention, the external image of the blood vessel can be calibrated by utilizing high precision of the intracavity image.

A retrieval catheter operable by a single clinician that will neither displace a deployed stent nor cause undue trauma to the vascular lumen or lesion. The retrieval catheter may be sized to accommodate both a guidewire and a balloon wire. The retrieval catheter is easy to navigate through tortuous passageways and will cross a previously deployed stent or stent-graft easily with minimal risk of snagging on the deployed stent or stent graft. The sheath and dilator are adapted to allow a guidewire or balloon wire to pass through the walls of both and to allow the sheath and dilator to move axially with respect to each other.

The present disclosure is directed a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method may include providing a first intravascular device having a distal portion and at least one aperture and positioning the distal portion of the first intravascular device in the vascular wall. The method may further include providing a reentry device having a body and a distal tip, the distal tip having a natural state and a compressed state and inserting the distal tip, in the compressed state, in the distal portion of the first intravascular device. The method may further include advancing the distal tip, in the natural state, through the at least one aperture of the first intravascular device.

An actuated telescoping system for navigation within a vascular lumen and thrombectomy of a thrombus. The system includes a tubular catheter member having an open distal end defining a catheter lumen, a vacuum source, a rotational drive system, a flexible shaft having a channel coupled to the rotational drive system for rotational movement in response thereto, and an optional guidewire selectively inserted at least partially within the flexible shaft. The flexible shaft is at least partially disposed within the tubular catheter member configured for uncoupled rotational and translational motion therein and to optionally define a corkscrew motion in response to rotational driving force by the drive system that results in formation of hydrodynamic vortices within the catheter lumen. The telescoping system can be capable of reversibly transitioning between navigation and thrombectomy modes by differentially disposing and actuating the components and enable faster, more efficient and simpler removal of thromboembolic material.

The invention discloses a microcirculation resistance index calculation method and device based on a multi-modal image, electronic equipment and a storage medium. Comprising the following steps: acquiring a multi-modal image of a target blood vessel section and performing blood vessel lumen contour extraction processing to obtain a blood vessel lumen contour extraction result of the target blood vessel section in each modal image; for each modal image, determining a far-end blood flow and a far-end blood vessel pressure difference of the target blood vessel section based on a blood vessel lumen contour extraction result of the target blood vessel section in the modal image and modal image imaging correlation parameters corresponding to the modal image; based on the near-end blood vessel pressure of the target blood vessel section, the weight data corresponding to each modal image and the far-end blood flow volume and the far-end blood vessel pressure difference of the target blood vessel section in each modal image, the blood vessel microcirculation resistance index of the target blood vessel section is calculated. The microcirculation resistance index of the target blood vessel segment is determined based on the multi-modal image, and the accuracy of the microcirculation resistance index of the target blood vessel segment is improved.

The application relates to a blood vessel model generation method, which comprises the following steps: performing first level set segmentation on a three-dimensional medical image containing blood vessels to obtain a first binary graph sequence containing all blood vessel lumens; selecting a blood vessel branch of interest from a blood vessel model generated based on the first binary graph sequence; extracting a center line and a line radius of the blood vessel branch of interest; generating an initial blood vessel branch of interest level set by using the center line and the line radius, and then performing second level set segmentation to obtain a second binary graph sequence containing only the blood vessel branch of interest, and generating a blood vessel model after reconstruction. The method optimizes the complicated preprocessing operation in the traditional method, improves the model generation speed on the basis of ensuring the model precision.

Telescopic, self-propelled, and side-pump atherectomy devices are provided, each with a flexible sheath, a helically fluted cutter, and a drive assembly. The drive assembly may have a flexible drive shaft that rotates and moves with the lumen of the flexible sheath, a positive displacement pump for transporting the cut tissue, and a flexible drive shaft that may be longer than the flexible sheath to allow reversible telescoping of the drive assembly away from the lumen of the flexible sheath. The positive displacement pump may be a screw pump with a portion of the drive screw exposed to contact the vascular lumen, allowing self-propulsion of the device through the vascular lumen. A reversibly expandable side-pump element may be included at the distal end of the flexible sheath to laterally push the cutter.Improved cutting heads and methods for their manufacture are provided, for cutting a combination of soft and hard plate.

The application discloses a cell-loaded porous hydrogel biomaterial and a preparation method and application thereof. The preparation method of the cell-loaded porous hydrogel biomaterial comprises the following steps: preparing a filamentous or multi-arm sacrificial hydrogel; preparing a matrix hydrogel precursor solution; wherein, the sacrificial hydrogel and / or the matrix hydrogel precursor solution are loaded with living cells; and mixing the sacrificial hydrogel and the matrix hydrogel precursor solution to obtain the cell-loaded porous hydrogel biomaterial. The special-shaped hydrogel such as the filamentous or multi-arm hydrogel is used as a sacrificial template, and after the sacrificial hydrogel is removed, a biomimetic blood vessel lumen form with better connectivity of the pore structure can be obtained, and cells can be loaded in the filamentous sacrificial hydrogel, so that the cells can be released in situ in the three-dimensional pore network, and secondary planting is not needed, and the efficiency and uniformity of cell planting are improved.

The application discloses a kind of based on intravascular imaging optimization three-dimensional vascular model interframe interpolation method;Obtain the sequence image group collected by intravascular imaging technology;And each frame image in sequence image group is carried out denoising processing;Using segmentation algorithm extracts the lumen boundary in each frame image, obtains the two-dimensional profile sequence image group of vascular lumen with frame data;Interpolation times are calculated;According to interpolation times, difference image group is generated, and according to the frame data of each image in difference image group, it is inserted into two-dimensional profile sequence image group;According to the last obtained two-dimensional profile sequence image group, generate high-resolution three-dimensional vascular model.The application is obtained by the frame interpolation technology of image collected by intravascular imaging technology, and the frame distance of adjacent image is reduced, and the continuity and smoothness of three-dimensional vascular model are improved.

This invention belongs to the field of medical interventional devices and 3D reconstruction technology, and particularly relates to a method and system for 3D reconstruction of vascular lumens for vascular interventional surgery. The method includes: controlling the catheter / guidewire within the interventional vessel to move back and forth along the vessel axis to obtain pose data from dual magnetic sensors; obtaining the current frame tangent vector and the tangent vector of the previous adjacent frame based on the pose data, and constructing a local coordinate system; obtaining the axial projection distance based on the pose data and the tangent vector of the previous adjacent frame, and constructing an adaptive radius core equation to obtain the true radius of the vascular lumen; calculating the catheter / guidewire bending angle based on the current frame tangent vector and the tangent vector of the previous adjacent frame, and determining the effective wall-attached frames; generating a point cloud set of the vascular lumen based on the effective wall-attached frames and the true radius of the vascular lumen; and generating a 3D mesh from the point cloud set to complete the 3D reconstruction of the vascular lumen. The solution of this invention is adaptable to vascular interventional scenarios, requires no active rotation, requires no additional image assistance, is low in cost, and has high accuracy.

The invention discloses an automatic pretreatment method for constructing a fluid domain grid based on a blood vessel wall facet. Comprising the steps that an intravascular imaging device generates a three-dimensional blood vessel wall facet file and converts the blood vessel wall facet file into a. Obj format; identifying and processing blood vessel wall facets formed in the blood vessel wall facet file, identifying openings, and numbering the openings in sequence; repairing each identified opening to form a watertight facet with a color attribute; and outputting the three-dimensional watertight blood fluid domain body grid. According to the method, the fluid domain body mesh is directly constructed based on the facet information, secondary processing such as curved surface fitting and smoothing on the blood vessel wall is not needed, the precise structure of the blood vessel lumen is kept, and subsequent high-precision numerical calculation is facilitated. The boundary information is determined by marking the repairing facet, manual analysis and boundary appointing through an interactive interface are not needed, the processing steps are simplified, the pretreatment time is shortened, and the operation complexity is reduced.

Circulatory assist devices and methods are disclosed herein. In some variations, a circulatory assist system may be configured for placement in a cardiovascular lumen (e.g., aorta) and include a pump arrangement comprising a pump region configured to receive blood, an outflow region, and a pump in the pump region and configured to drive the received blood toward the outflow region. The circulatory assist system may further include a vascular seal configured to form a peripheral seal between the pump arrangement and an inner wall of the cardiovascular lumen.

The utility model generally relates to the technical field of medical instruments, in particular to a vascular bypass end-side anastomosis deformable supporting device which comprises a main supporting body, an auxiliary supporting body and a connecting piece. The main supporting body is used for being arranged in a receptor blood vessel lumen to expand the vessel wall to assist anastomosis. The auxiliary supporting body is arranged on the main supporting body and used for being placed in a donor blood vessel lumen to expand the vessel wall for end-side anastomosis. The connecting piece is connected to the main supporting body and / or the auxiliary supporting body. The main support body is arranged in the lumen to expand and support the proximal end and the telecentric end of a receptor blood vessel; and expanding and supporting the donor blood vessel through the auxiliary support body, and performing end-side anastomosis. The three-way lumen of a donor blood vessel and a receptor blood vessel is internally supported, anastomotic stoma suturing is completed under supporting, knotting is not performed after two-needle suturing, the supporting body is pulled out from the unknotted opening through the connecting piece, and finally knotting is performed to seal the whole anastomotic stoma. An anastomosis platform with a clear visual field is established for an operator, and the probability of technical errors is reduced.

Systems and methods disclosed herein provide a method for real-time PCI steering. A method includes receiving one or more images of a blood vessel from an imaging modality system, the blood vessel having a lumen, a lumen surface, and a wall; constructing a 3D model of the blood vessel based on the one or more images; segmenting one or more materials between the lumen and the wall of the blood vessel; reconstructing the blood vessel based on the one or more images; assigning material characteristics to the reconstructed surface of the blood vessel; determining wall thickness, plaque thickness, lumen area, plaque eccentricity, and one or more plaque components; real-time guidance of an interventional procedure based on the 3D reconstructed vascular lumen surface and the segmented material; and performing balloon pre-dilation, percutaneous coronary intervention, and post-balloon dilation using the 3D reconstructed vascular lumen surface and the segmented material.

An apparatus includes processor circuitry configured to communicate with an intravascular imaging catheter. The processor circuitry is configured to output a first screen display to a display in communication with the processor circuitry, the first screen display including an intravascular image obtained by the intravascular imaging catheter, wherein the intravascular image includes a vascular lumen and vascular tissue. The processor circuitry is further configured to: receive a single user input on the intravascular image identifying a location within a region of interest; and automatically determine the boundary of the region of interest in response to the single user input, wherein the boundary surrounds the location identified by the single user input. The processor circuitry is further configured to output a second screen display to the display, the second screen display including the intravascular image and the boundary of the region of interest superimposed on the intravascular image.

A cannula system for intubating a blood vessel has a cannula having a distal end and a proximal end. The cannula defines a cannula lumen. The cannula system also includes a tip on the distal end of the cannula. The tip defines a tip lumen connected to the cannula lumen. The tip is changeable between a first shape and a second shape. The first shape has a first width dimensioned to fit through a lumen of a blood vessel. The second shape has a second width that is greater than the first width and is sized to engage the vascular lumen and secure the tip in position within the vascular lumen.

This application relates to an external catheter, a delivery component, and a delivery system. The main catheter body has an axial lumen and includes an external catheter bendable section and an external catheter push section along the axial direction. The external catheter bendable section has a first axial bending resistance portion extending along the axial direction. The first axial bending resistance portion is configured to resist bending of the external catheter bendable section along the axial plane in which the first axial bending resistance portion is located. The external catheter push section has a second axial bending resistance portion extending along the axial direction. The second axial bending resistance portion is configured to resist bending of the external catheter push section along the axial plane in which the second axial bending resistance portion is located. An angle may be formed between the axial planes of the first and second axial bending resistance portions. This configuration creates a circumferential angular misalignment between the first and second axial bending resistance portions of the external catheter, allowing them to bend in different planes, enabling three-dimensional bending of the external catheter and smooth passage through various vascular lumens of various shapes within the body.

The application discloses a recyclable intracranial artery stent system and belongs to the technical field of medical auxiliary instruments. The recyclable intracranial artery stent system comprises a stent and a recycling device. The stent comprises a stent body and a recyclable joint arranged at the proximal end of the stent body. The recycling device comprises a recycling catheter, a push rod and a recycling cage. The push rod is arranged inside the recycling catheter and can slide in the recycling catheter. The recycling cage is connected to the distal end of the push rod and can grasp the joint for recycling. The recyclable intracranial artery stent system can relieve intracranial artery stenosis in a short period, repair the vascular lumen structure, and take out the stent from the body after the intracranial artery lumen structure is repaired and stabilized, thereby avoiding long-term retention of the stent and effectively reducing the loss of the effective lumen of the intracranial artery. The stent can be recycled and replaced according to the recovery of the blood vessel and the stent fitting degree, the treatment scheme can be adjusted in the subsequent period, the problem of in-stent restenosis is solved, and the treatment effect of patients with intracranial artery stenosis is ensured.

The application discloses an estimation method of an angle between an ultrasonic beam and a blood flow movement direction, a calibration system and a method. The estimation method of the angle between the ultrasonic beam and the blood flow movement direction comprises the following steps: training a neural network model based on image datasets composed of ultrasonic blood vessel wall images with different deflection angles of different blood vessels in advance; calling the neural network model to segment an ultrasonic blood vessel wall image of a blood vessel to be estimated to obtain a blood vessel cross-section graph; acquiring pixel points forming a blood vessel lumen boundary and calculating a lumen area; analyzing time sequence changes of the lumen area by using a time sequence analysis method; if the time sequence changes of the lumen area are stable, fitting an elliptical geometric graph corresponding to the blood vessel cross-section; otherwise, fitting a convex hull geometric graph; and estimating the angle between the ultrasonic beam and the blood flow movement direction by using a formula, wherein a is a long semi-axis of the geometric graph, and b is a short semi-axis of the geometric graph. The application can accurately estimate the angle between the ultrasonic beam and the blood flow movement direction.

This invention relates to a non-vascular lumen stent and its preparation method. The non-vascular lumen stent includes a stent body and an anti-displacement protrusion structure. The stent body is configured as a mesh-like structure, which is formed by spirally winding and interweaving at least one braided filament along the axial direction. The anti-displacement protrusion structure is formed by winding the anti-displacement protrusion structure braided filament, protruding from the outer surface of the stent body and inclined relative to the axial direction of the stent body. The stent body and the anti-displacement protrusion structure are integrally wound from the anti-displacement protrusion structure braided filament.

The application discloses application of all-trans retinoic acid in preparation of a drug for hemangiogenic differentiation of dental pulp stem cells, wherein the hemangiogenic differentiation comprises at least one of the following cases: at least one of the following is increased: tubule length, connection point number, blood vessel lumen volume and lumen number; blood vessel extension length is increased or sprouting is increased; blood vessel formation speed is accelerated; blood vessel density is increased; and expression amount of a blood vessel regulation related gene or amount of a related protein is increased. The application finds that a retinoic acid signal channel is a candidate target point for promoting hemangiogenic differentiation of the dental pulp stem cells in a starvation environment and can be applied to dental pulp regeneration treatment, and therefore, the application has a wide application prospect in the field of the dental pulp regeneration treatment.

The invention discloses an inter-frame interpolation method for optimizing a three-dimensional blood vessel model based on intravascular imaging. Acquiring a sequence image group acquired by an intravascular imaging technology; carrying out denoising processing on each frame of image in the sequence image group; extracting a lumen boundary in each frame of image by adopting a segmentation algorithm to obtain a two-dimensional contour sequence image group of the blood vessel lumen with frame data; calculating the number of interpolations; generating a difference image group according to the interpolation times, and inserting the frame data of each image in the difference image group into the two-dimensional contour sequence image group; and generating a high-resolution three-dimensional blood vessel model according to the finally obtained two-dimensional contour sequence image group. According to the invention, through the inter-frame interpolation technology of the images acquired by the intravascular imaging technology, the frame distance between the adjacent images is reduced, and the continuity and smoothness of the three-dimensional blood vessel model are improved.