70 results about "Piroxicam" patented technology

An analgesic composition, is disclosed which comprises a mixture of piroxicam, dexamethasone, ketamine, lidocaine injection, dimethyl sulfoxide, gabapentin and Vanicream™, preferably in the form of a cream or ointment. The composition is applied topically for the relief of pain of arthritis, neuropathy, post-herpetic (shingles) conditions, sore muscles, tendons and ligaments, and local reactions to insect bites or stings.

The invention provides a herbal formulation useful as a therapeutic and cosmetic applications for the treatment of general skin disorders, the composition comprising at least two or more plant extracts in the form of oil or powder or mixtures thereof, the plant extracts being selected from the group consisting of Gymnena sylvestrae water extract 3 to 6 wt. %; Tridax procumbens water extract 3 to 6 wt. %; its methanolic extract 4 to 6 wt. %, Allium sativum oil hexane extract 1 to 3 wt. %; dried juice of Aloe vera 2 to 6 wt. %; Gum Olibanum powder in the natural form 4 to 7 wt. %; Gum Olibanum resinoid organic solvent extract 3 to 8 wt. %; and resinoid free Gum Olibanum meal 5 to 10 wt. %., optionally, including any drug having anti-inflammatory and wound healing property or mixture thereof, the drug being selected from the group consisting of Disclofenac sodium 1-3 wt. %, Salicyclic acid 1 to 4 wt. %, Piroxicam 1 to 2 wt. %, Turmeric powder 0.1 to 1 wt. %, a base containing aqueous cream or a gel containing carbopol ranging between 1 to 4 wt. %, emulsifying ointment ranging between 20 to 40 wt. %, preservatives ranging between 0.05-0.3% and a humecant ranging between 1-4 wt. %, and remaining water to make 100 wt. %.

The present invention provides a topical formulation containing NSAID, particularly diclofenac. The topical formulation is particularly useful for alleviating pain/inflammation associated with infection caused by herpes virus, especially herpes simplex virus (HSV) and varicella-zoster virus (VZV). Similar relief can be achieved where diclofenac is replaced with another non-steroidal anti-inflammatory drug (NSAID), which includes, without limitation, etodolac, ketorolac, bromfenac, diflunisal, ibuprofen, fenoprofen, ketoprofen, naproxen, suprofen, meclofenamate, mefenamic acid, piroxicam, meloxicam, indomethacin, sulindac, phenylbutazone, oxyphenbutazone, and tolmetin. The topical formulation is further characterized by its fast relief on pain and/or inflammation associated with infection caused by herpes virus, i.e., a complete relief in no more than seven (7) days after the application of the topical formulation on skins of patients.

The invention belongs to the technical field of detection of traditional Chinese medicine preparations, particularly relates to a detection card for rapidly detecting content of illegally added piroxicam (PIR) in traditional Chinese medicine preparations capable of dispelling wind and eliminating dampness and further discloses a method for rapidly detecting content of illegally added piroxicam intraditional Chinese medicine preparations capable of dispelling wind and eliminating dampness. Through the detection card for rapidly detecting content of the illegally added piroxicam in traditionalChinese medicine preparations capable of dispelling wind and eliminating dampness, reaction processes of extracting and developing the piroxicam in traditional Chinese medicine preparations are capable of rapidly carrying out qualitative detection of piroxicam added in the traditional Chinese medicine preparations; a handheld machine capable of carrying out qualitative analysis in the prior art isused for carrying out qualitative detection of the content of piroxicam; the detection card can be used for carrying out rapid on-site detection on the content of the chemical component which is piroxicam in Chinese patent medicines capable of dispelling wind and eliminating dampness; the defects of high cost and high time consumption of the existing instruments are overcome; the problems of highpossibility of occurrence wrong detection and detection omission due to diversity of interference factors in the samples of the existing kit are solved.

A transdermal composition and method to be used as a treatment for plantar fasciitis is provided. Transdermal composition may include a combination of about 2% w/w to about 5% w/w of piroxicam and about 95% w/w to about 98% w/w of a natural permeation enhancement (NPE) composition. The NPE composition may increase the skin permeability, enhancing the transdermal delivery flux of piroxicam via a single transdermal application, thus, reducing the time of treatment. Transdermal composition may be applied upon an area of treatment, which may include myofascial trigger points linked to pain caused by plantar fasciitis, thus treating this condition more effectively. Moreover, employing a long acting NSAID such as piroxicam, in combination with the NPE composition, may act as a faster and effective treatment for an inflammatory process compared to typical treatments.

The invention relates to a piroxicam-containing transdermal-absorption preparation and a preparation method thereof. The transdermal-absorption preparation comprises piroxicam serving as an active ingredient, and levobupivacaine or pharmaceutically acceptable salt thereof serving as an absorption enhancer. According to the transdermal absorption preparation, the piroxicam has extremely excellent transdermal absorbability due to the absorption promoting effect of the levobupivacaine, and the effect is a specific effect generated by the combination of levobupivacaine and piroxicam, wherein a relatively good effect can be achieved as long as a small amount of levobupivacaine is provided. The piroxicam-containing transdermal absorption preparation, namely a patch, is extremely useful in clinical application and has a great medical effect.

The invention relates to a pharmaceutical preparation of piroxicam and process for preparation, wherein the pharmaceutical preparation comprises 0.5-10 weight parts of piroxicam as active composition, 5-95 weight parts of medicinal adjuvant, and 5-90 weight parts of casting agent. The preparation has the advantages of easiness in use, higher safety and reliability, and better analgesic and analgesic effects.

The present invention discloses a Fengtongning composite preparation and a preparation method thereof. The composite preparation is prepared from the following raw medicines, by weight, 6-12 parts of thunder god vine, 8-20 parts of sabia japonica maxim, 7-15 parts of incised notopterygium rhizome and root, 6-12 parts of wild celery, 3-10 parts of rheum, 6-12 parts of common monkshood mother-root, 5-10 parts of angelica archang lica, 7-15 parts of kusnezoff monkshood mother-root, 7-15 parts of angelica, 8-20 parts of Chinese clematis root and rhizome, 8-15 parts of piroxicam, 10-20 parts of diclofenac sodium, 7-15 parts of oryzanol, 8-18 parts of vitamin B1, and 6-12 parts of vitamin B6. The composite preparation has effects of rheumatism removing, blood circulation activating, blood stasis dissipating, meridian passage dredging, swelling subsiding and analgesia, and provides significant treatment effects for bone and muscle pain, gouty arthritis, rheumatism, rheumatoid arthritis, osteoarthritis and the like, wherein the total efficiency is 97.35%.

The invention provides a piroxicam gel preparation and a preparation method of the piroxicam gel preparation. The gel preparation comprises the following components in percentages by weight: 0.1-1% of piroxicam, 0.3-1.2% of Carbomer 940, 0.1-1% of tromethamine, 1-10% of ethanol, 6-15% of propylene glycol, 0.6-1.5% polyethylene glycol 400, 0.006-0.015%Edetate Disodium, and 1.2-2.1% of triethanolamine. Piroxicam is dissolved by using tromethamine to solve the problem that tromethamine is difficult to dissolve in water, the penetrability of piroxicam to the skin is improved, the absorption rate of piroxicam through the skin is increased, the curative effect is obviously improved by local topical administration for curing the local pain, and a novel administration method for the patients is also provided. The gel preparation is semi-solid gel having good transdermal absorption property; the piroxicam is completely dissolved and dispersed in the gel preparation, thereby facilitating the pain relief for the patient. The preparation process is simple, and the preparation is stable and reliable in quality.

The invention provides a Chinese and western medicine compound medicine for treating osteoarthritis. The Chinese and western medicine compound medicine for treating osteoarthritis is composed of traditional Chinese medicine components and western medicine components, the traditional Chinese medicine components comprise Chinese starjasmine stem, radix salviae miltiorrhizae, radix astragali, liquorice, native copper, herba epimedii and radix cyathulae, and the western medicine components comprise glucosamine, yak bone collagen peptide, piroxicam and aluminum hydroxide. The natural Chinese herbalmedicines and western medicines are organically combined, compatibility and applicability of the Chinese and western medicines are adjusted, and the Chinese and western medicine compound medicine fortreating osteoarthritis is prepared. The Chinese and western medicine compound medicine for treating osteoarthritis improves a microcirculation, promotes blood flow, reduces swelling and pain, increases bone density while quickly treating osteoarthritis, protects gastric mucosa, avoids side effects, has a good applicability to patients, and fundamentally improves healing effects of patients withmild, moderate and severe osteoarthritis.

The invention discloses application of piroxicam in preparation of a medicine for treating skin ulcer and a preparation method of the medicine. The medicine is prepared from piroxicam and pharmaceutically acceptable auxiliary materials. The piroxicam can promote migration of human umbilical vein endothelial cells (HUVEC cells) under high glucose stimulation, so that healing of diabetic foot ulcerwounds is promoted; and the piroxicam has a remarkable curative effect on skin ulcer, especially diabetic foot ulcer.

An adhesive patch is provided in which piroxicam is formulated as a non-steroidal anti-inflammatory analgesic. In particular, provided is a piroxicam-containing transdermally absorbable adhesive patch in which an absorption promoter to piroxicam is formulated to achieve high anti-inflammatory and analgesic effects without inhibiting releasing of these drugs. The piroxicam-containing transdermally absorbable adhesive patch contains piroxicam as a medicinal component and oxybuprocaine or a pharmaceutically acceptable salt thereof as an absorption promoter. In the piroxicam-containing transdermally absorbable adhesive patch, the content of piroxicam is from 0.1% to 5% by weight to the total weight of a drug-containing plaster and the content of oxybuprocaine or the pharmaceutically acceptable salt thereof is from 1% to 30% by weight to the total weight of the drug-containing plaster.

The invention discloses piroxicam tablets and a preparation process and purposes thereof. The product consists of piroxicam, lactose, pregelatinized starch, hydroxypropyl methyl cellulose, carboxymethyl starch sodium, polysorbate-80, 15% pregelatinized starch for slushing, superfine silica powder, magnesium stearate and a gastric soluble film coating premix. The production method comprises the steps: preparing tablet cores, coating and the like. The piroxicam tablets are used for treating 30 cases of rheumatoid arthritis, have good curative effects of diminishing inflammation and relieving pain and have slight influence on erythrocyte sedimentation rate, the total effective rate is 88 percent, and the piroxicam tablets have the characteristics of low administration frequency, stable blood concentration, long duration and the like.

The invention discloses an eye nursing gel and a preparation method of the eye nursing gel. The eye nursing gel is mainly prepared from the following components in parts by weight: 3-10 parts of hydroxypropyl methyl cellulose, 1-4 parts of guar gum, 0.1-0.3 part of nedocromil sodium, 0.1-0.5 part of betaxolol, 0.2-0.6 part of piroxicam, 0.1-0.3 part of sulphate, 0.1-0.2 part of dipotassium glycyrrhizinate, 0.05-0.15 part of bacitracin, 0.8-1.2 parts of epinephrine bitartrate, 1.5-3 parts of taurine, 0.3-1 part of procyanidine, 0.4-1 part of vitamin A, 0.4-1 part of vitamin B12, 0.01-0.03 part of a preservative, 2-5 parts of a buffer agent, 2-8 parts of an iso-osmotic agent, and 70-120 parts of a gel substrate. According to the eye nursing gel, the components are mixed to accelerate the recovery of the injured eye tissue, prevent the infectious complications, and alleviate the eye discomfort, and therefore, a very good nursing role is played on the eyes; the eye nursing gel can effectively alleviate eyestrain, eliminate black eyes and edemas on the peripheries of the eyes, resist wrinkles as well as activate and relax the skin, and has certain effects for preventing shortsightedness, recovering the vision health, controlling and preventing eye diseases, and the like.

The invention discloses a 1,3-benzothiazinone compound which has a chemical structural formula as shown in the description, in the formula, R1 is C1-C4 straight chain alkyl or methyl carbethoxy respectively; and R2 is a heterocyclic compound or substituted phenyl. The compound disclosed by the invention has activity equivalent to or higher than those of known medicines such as meloxicam and piroxicam at a cell level, has anti-inflammation, anti-cancer and antibacterial activity, has toxicity lower than those of xicam compounds in the market, and is safe and effective.